Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Feb;71(1):1-12. doi: 10.4149/neo_2024_230907N475. Epub 2024 Jan 31.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal in cance...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
The role of polyethylenimine-functionalized gold nanoclusters carrying plasmid CMTM5 in impeding the malignant progression of prostate cancer cells by promoting EGFR endocytosis
In conclusion, the PEI-AuNCs nano-delivery system exhibits good biocompatibility and efficaciously conveys pCMTM5 to PCa cells. Crucially, pCMTM5 does not directly interact with EGFR, and CMTM5 governs the malignant progression of PC3 cells by promoting EGFR endocytosis.PMID:38295104 | DOI:10.4149/neo_2024_231018N544 (Source: Neoplasma)
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Linjin Li Chengpeng Li Feilong Miao Wu Chen Xianghui Kong Ruxian Ye Rui Feng Source Type: research
Expression patterns and pathogenesis of Semaphorin class 4 subfamily proteins in solid tumors
Neoplasma. 2024 Jan 31:230907N475. doi: 10.4149/neo_2024_230907N475. Online ahead of print.ABSTRACTSemaphorins are originally described as regulators of nervous system development. Besides, members of the semaphorin family play important roles in the growth, metastasis, and angiogenesis of solid tumors. In contrast to the other semaphorin subclasses, semaphorin class 4 has both membrane-bound and active soluble forms. Soluble class 4 semaphorins in body fluids (blood and saliva) may serve as potential biomarkers for early diagnosis and prognosis prediction of specific cancers. The class 4 semaphorins also transduce signal ...
Source: Neoplasma - January 31, 2024 Category: Cancer & Oncology Authors: Dongjun Jiang Xiaoli Chen Xiuting Li Jian Qiu Peng Xu Xuezhi Li Source Type: research
