A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers
CONCLUSION: This study successfully developed and validated a novel, robust, sensitive, and specific plasma-based DNA methylation panel, offering a promising strategy for the early detection of GICs.PMID:37918207 | DOI:10.1016/j.neo.2023.100941 (Source: Neoplasia)
Source: Neoplasia - November 2, 2023 Category: Cancer & Oncology Authors: Yanmiao Dai Hui Li Qianqian Wu Jie Wang Kai Wang Sujuan Fei Bing Pei Lishuang Song Guangxia Chen Yong Ma Chenjing Xia Shangmin Xiong Minxue Zheng Ying Xue Guodong Zhao Hongwei Xu Source Type: research
A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers
CONCLUSION: This study successfully developed and validated a novel, robust, sensitive, and specific plasma-based DNA methylation panel, offering a promising strategy for the early detection of GICs.PMID:37918207 | DOI:10.1016/j.neo.2023.100941 (Source: Neoplasia)
Source: Neoplasia - November 2, 2023 Category: Cancer & Oncology Authors: Yanmiao Dai Hui Li Qianqian Wu Jie Wang Kai Wang Sujuan Fei Bing Pei Lishuang Song Guangxia Chen Yong Ma Chenjing Xia Shangmin Xiong Minxue Zheng Ying Xue Guodong Zhao Hongwei Xu Source Type: research
A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers
CONCLUSION: This study successfully developed and validated a novel, robust, sensitive, and specific plasma-based DNA methylation panel, offering a promising strategy for the early detection of GICs.PMID:37918207 | DOI:10.1016/j.neo.2023.100941 (Source: Neoplasia)
Source: Neoplasia - November 2, 2023 Category: Cancer & Oncology Authors: Yanmiao Dai Hui Li Qianqian Wu Jie Wang Kai Wang Sujuan Fei Bing Pei Lishuang Song Guangxia Chen Yong Ma Chenjing Xia Shangmin Xiong Minxue Zheng Ying Xue Guodong Zhao Hongwei Xu Source Type: research
A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers
CONCLUSION: This study successfully developed and validated a novel, robust, sensitive, and specific plasma-based DNA methylation panel, offering a promising strategy for the early detection of GICs.PMID:37918207 | DOI:10.1016/j.neo.2023.100941 (Source: Neoplasia)
Source: Neoplasia - November 2, 2023 Category: Cancer & Oncology Authors: Yanmiao Dai Hui Li Qianqian Wu Jie Wang Kai Wang Sujuan Fei Bing Pei Lishuang Song Guangxia Chen Yong Ma Chenjing Xia Shangmin Xiong Minxue Zheng Ying Xue Guodong Zhao Hongwei Xu Source Type: research
Acral melanoma: new insights into the immune and genomic landscape
Neoplasia. 2023 Oct 30;46:100947. doi: 10.1016/j.neo.2023.100947. Online ahead of print.ABSTRACTAcral melanoma is a rare subtype of melanoma that arises on the non-hair bearing skin of the nail bed, palms of the hand and soles of the feet. It is unique among melanomas in not being linked to ultraviolet radiation (UVR) exposure from the sun, and, as such, its incidence is similar across populations who are of Asian, Hispanic, African and European origin. Although research into acral melanoma has lagged behind that of sun-exposed cutaneous melanoma, recent studies have begun to address the unique genetics and immune features...
Source: Neoplasia - November 1, 2023 Category: Cancer & Oncology Authors: Larissa Anastacio DaCosta Carvalho Flavia C Aguiar Keiran S M Smalley Patricia A Possik Source Type: research
Innate immunity: Looking beyond T-cells in radiation and immunotherapy combinations
Neoplasia. 2023 Oct 30;46:100940. doi: 10.1016/j.neo.2023.100940. Online ahead of print.ABSTRACTRadiation therapy is an established and effective anti-cancer treatment modality. Extensive pre-clinical experimentation has demonstrated that the pro-inflammatory properties of irradiation may be synergistic with checkpoint immunotherapy. Radiation induces double-stranded DNA breaks (dsDNA). Sensing of the dsDNA activates the cGAS/STING pathway, producing Type 1 interferons essential to recruiting antigen-presenting cells (APCs). Radiation promotes cytotoxic CD8 T-cell recruitment by releasing tumour-associated antigens capture...
Source: Neoplasia - November 1, 2023 Category: Cancer & Oncology Authors: R A McMahon C D'Souza P J Neeson S Siva Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | PMC:PMC9630038 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | PMC:PMC9630038 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | PMC:PMC9630038 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | PMC:PMC9630038 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | PMC:PMC9630038 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Corrigendum to Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1 α/miR-494/Survivin signaling pathway [Volume 32 Number xxx Month 2022 pp. 100821]
Neoplasia. 2022 Dec;34:100843. doi: 10.1016/j.neo.2022.100843. Epub 2022 Oct 22.NO ABSTRACTPMID:37873727 | DOI:10.1016/j.neo.2022.100843 (Source: Neoplasia)
Source: Neoplasia - October 24, 2023 Category: Cancer & Oncology Authors: Hongchang Li Xianhao Su Jindong Li Weiyan Liu Gaofeng Pan Anwei Mao Jiazhe Liu Qing Zhang Longhua Rao Xiaofeng Xie Xia Sheng Source Type: research
Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells
CONCLUSION: Our data with the HPV-dependent release of HMGB1 and increased expression of CD137 following RCT provide a hint for increased immunogenicity underlining the better prognosis for HPV positive tumors following RCT.PMID:37857049 | PMC:PMC10589749 | DOI:10.1016/j.neo.2023.100944 (Source: Neoplasia)
Source: Neoplasia - October 19, 2023 Category: Cancer & Oncology Authors: Fridolin Grottker Simon Gehre Clara M Reichardt Azzaya Sengedorj Tina Jost Thorsten Rieckmann Markus Hecht Antoniu-Oreste Gostian Benjamin Frey Rainer Fietkau Udo S Gaipl Michael R ückert Source Type: research
Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells
CONCLUSION: Our data with the HPV-dependent release of HMGB1 and increased expression of CD137 following RCT provide a hint for increased immunogenicity underlining the better prognosis for HPV positive tumors following RCT.PMID:37857049 | PMC:PMC10589749 | DOI:10.1016/j.neo.2023.100944 (Source: Neoplasia)
Source: Neoplasia - October 19, 2023 Category: Cancer & Oncology Authors: Fridolin Grottker Simon Gehre Clara M Reichardt Azzaya Sengedorj Tina Jost Thorsten Rieckmann Markus Hecht Antoniu-Oreste Gostian Benjamin Frey Rainer Fietkau Udo S Gaipl Michael R ückert Source Type: research
