The Utility of Urinary NGAL as an Alternative for Serum Creatinine to Detect Acute Kidney Injury in Infants Exposed to Nephrotoxic Medications in the Neonatal Intensive Care Unit
CONCLUSION: We propose that uNGAL could be used to screen for NTM-AKI and thus replace many blood draws needed in those exposed to NTM. The ideal uNGAL threshold requires further investigation in infants.PMID:38151013 | DOI:10.1159/000535322 (Source: Neonatology)
Source: Neonatology - December 27, 2023 Category: Perinatology & Neonatology Authors: Christine Stoops Hailey Gavigan Kelli Krallman Nekayla Anderson Russell Griffin Cara Slagle Scott House S L Goldstein D J Askenazi Source Type: research

The Utility of Urinary NGAL as an Alternative for Serum Creatinine to Detect Acute Kidney Injury in Infants Exposed to Nephrotoxic Medications in the Neonatal Intensive Care Unit
CONCLUSION: We propose that uNGAL could be used to screen for NTM-AKI and thus replace many blood draws needed in those exposed to NTM. The ideal uNGAL threshold requires further investigation in infants.PMID:38151013 | DOI:10.1159/000535322 (Source: Neonatology)
Source: Neonatology - December 27, 2023 Category: Perinatology & Neonatology Authors: Christine Stoops Hailey Gavigan Kelli Krallman Nekayla Anderson Russell Griffin Cara Slagle Scott House S L Goldstein D J Askenazi Source Type: research

The Utility of Urinary NGAL as an Alternative for Serum Creatinine to Detect Acute Kidney Injury in Infants Exposed to Nephrotoxic Medications in the Neonatal Intensive Care Unit
CONCLUSION: We propose that uNGAL could be used to screen for NTM-AKI and thus replace many blood draws needed in those exposed to NTM. The ideal uNGAL threshold requires further investigation in infants.PMID:38151013 | DOI:10.1159/000535322 (Source: Neonatology)
Source: Neonatology - December 27, 2023 Category: Perinatology & Neonatology Authors: Christine Stoops Hailey Gavigan Kelli Krallman Nekayla Anderson Russell Griffin Cara Slagle Scott House S L Goldstein D J Askenazi Source Type: research

Efficacy of Levetiracetam as Add-On Therapy in the Treatment of Seizures in Neonates
DISCUSSION: Although the cumulative loading dose of LEV was low and the group of infants studied was heterogeneous, the efficacy of LEV as add-on therapy for the treatment of seizures in neonates was limited. The highest seizure reduction rate was seen after LDC administration.PMID:38113859 | DOI:10.1159/000535499 (Source: Neonatology)
Source: Neonatology - December 19, 2023 Category: Perinatology & Neonatology Authors: Mathies Rondagh Linda S De Vries Cacha M P C D Peeters-Scholte Selma C Tromp Sylke J Steggerda Source Type: research

Efficacy of Levetiracetam as Add-On Therapy in the Treatment of Seizures in Neonates
DISCUSSION: Although the cumulative loading dose of LEV was low and the group of infants studied was heterogeneous, the efficacy of LEV as add-on therapy for the treatment of seizures in neonates was limited. The highest seizure reduction rate was seen after LDC administration.PMID:38113859 | DOI:10.1159/000535499 (Source: Neonatology)
Source: Neonatology - December 19, 2023 Category: Perinatology & Neonatology Authors: Mathies Rondagh Linda S De Vries Cacha M P C D Peeters-Scholte Selma C Tromp Sylke J Steggerda Source Type: research

Efficacy of Levetiracetam as Add-On Therapy in the Treatment of Seizures in Neonates
DISCUSSION: Although the cumulative loading dose of LEV was low and the group of infants studied was heterogeneous, the efficacy of LEV as add-on therapy for the treatment of seizures in neonates was limited. The highest seizure reduction rate was seen after LDC administration.PMID:38113859 | DOI:10.1159/000535499 (Source: Neonatology)
Source: Neonatology - December 19, 2023 Category: Perinatology & Neonatology Authors: Mathies Rondagh Linda S De Vries Cacha M P C D Peeters-Scholte Selma C Tromp Sylke J Steggerda Source Type: research

Efficacy of Levetiracetam as Add-On Therapy in the Treatment of Seizures in Neonates
DISCUSSION: Although the cumulative loading dose of LEV was low and the group of infants studied was heterogeneous, the efficacy of LEV as add-on therapy for the treatment of seizures in neonates was limited. The highest seizure reduction rate was seen after LDC administration.PMID:38113859 | DOI:10.1159/000535499 (Source: Neonatology)
Source: Neonatology - December 19, 2023 Category: Perinatology & Neonatology Authors: Mathies Rondagh Linda S De Vries Cacha M P C D Peeters-Scholte Selma C Tromp Sylke J Steggerda Source Type: research

Efficacy of Levetiracetam as Add-On Therapy in the Treatment of Seizures in Neonates
DISCUSSION: Although the cumulative loading dose of LEV was low and the group of infants studied was heterogeneous, the efficacy of LEV as add-on therapy for the treatment of seizures in neonates was limited. The highest seizure reduction rate was seen after LDC administration.PMID:38113859 | DOI:10.1159/000535499 (Source: Neonatology)
Source: Neonatology - December 19, 2023 Category: Perinatology & Neonatology Authors: Mathies Rondagh Linda S De Vries Cacha M P C D Peeters-Scholte Selma C Tromp Sylke J Steggerda Source Type: research

Efficacy of Levetiracetam as Add-On Therapy in the Treatment of Seizures in Neonates
DISCUSSION: Although the cumulative loading dose of LEV was low and the group of infants studied was heterogeneous, the efficacy of LEV as add-on therapy for the treatment of seizures in neonates was limited. The highest seizure reduction rate was seen after LDC administration.PMID:38113859 | DOI:10.1159/000535499 (Source: Neonatology)
Source: Neonatology - December 19, 2023 Category: Perinatology & Neonatology Authors: Mathies Rondagh Linda S De Vries Cacha M P C D Peeters-Scholte Selma C Tromp Sylke J Steggerda Source Type: research

Intrauterine Inflammation, Excessive Fetal Growth and Respiratory Morbidities in Moderate-To-Late Preterm Neonates
CONCLUSION: Together with the incidence of respiratory distress syndrome and gestational age, chorioamnionitis and high birth-weight z-scores were associated with an increased incidence of respiratory morbidities in moderate-to-late preterm neonates. The deleterious impact of intrauterine inflammation on the lungs may be common in neonates of virtually all gestational ages. Traditional admission policy of neonatal intensive care units based on a threshold birth-weight, may leave a group of neonates without close observation despite their increased risks for respiratory morbidities.PMID:38104557 | DOI:10.1159/000534163 (Source: Neonatology)
Source: Neonatology - December 17, 2023 Category: Perinatology & Neonatology Authors: Kyoko Yokoi Osuke Iwata Satoru Kobayashi Hideo Jinnou Shin Kato Shinji Saitoh Haruo Goto Source Type: research

Intrauterine Inflammation, Excessive Fetal Growth and Respiratory Morbidities in Moderate-To-Late Preterm Neonates
CONCLUSION: Together with the incidence of respiratory distress syndrome and gestational age, chorioamnionitis and high birth-weight z-scores were associated with an increased incidence of respiratory morbidities in moderate-to-late preterm neonates. The deleterious impact of intrauterine inflammation on the lungs may be common in neonates of virtually all gestational ages. Traditional admission policy of neonatal intensive care units based on a threshold birth-weight, may leave a group of neonates without close observation despite their increased risks for respiratory morbidities.PMID:38104557 | DOI:10.1159/000534163 (Source: Neonatology)
Source: Neonatology - December 17, 2023 Category: Perinatology & Neonatology Authors: Kyoko Yokoi Osuke Iwata Satoru Kobayashi Hideo Jinnou Shin Kato Shinji Saitoh Haruo Goto Source Type: research

Intrauterine Inflammation, Excessive Fetal Growth and Respiratory Morbidities in Moderate-To-Late Preterm Neonates
CONCLUSION: Together with the incidence of respiratory distress syndrome and gestational age, chorioamnionitis and high birth-weight z-scores were associated with an increased incidence of respiratory morbidities in moderate-to-late preterm neonates. The deleterious impact of intrauterine inflammation on the lungs may be common in neonates of virtually all gestational ages. Traditional admission policy of neonatal intensive care units based on a threshold birth-weight, may leave a group of neonates without close observation despite their increased risks for respiratory morbidities.PMID:38104557 | DOI:10.1159/000534163 (Source: Neonatology)
Source: Neonatology - December 17, 2023 Category: Perinatology & Neonatology Authors: Kyoko Yokoi Osuke Iwata Satoru Kobayashi Hideo Jinnou Shin Kato Shinji Saitoh Haruo Goto Source Type: research

Preterm Formula, Fortified or Unfortified Human Milk for Very Preterm Infants, the PREMFOOD Study: A Parallel Randomised Feasibility Trial
CONCLUSIONS: Randomisation to UHM, FHM, and PTF diets by opt-out consent was acceptable to parents and clinical teams, associated with safe growth profiles and no significant differences in body composition. Our data provide justification to proceed to a larger RCT.PMID:38091960 | DOI:10.1159/000535498 (Source: Neonatology)
Source: Neonatology - December 13, 2023 Category: Perinatology & Neonatology Authors: Luke Mills Karyn E Chappell Robby Emsley Afshin Alavi Izabela Andrzejewska Shalini Santhakumaran Richard Nicholl John Chang Sabita Uthaya Neena Modi Source Type: research

Preterm Formula, Fortified or Unfortified Human Milk for Very Preterm Infants, the PREMFOOD Study: A Parallel Randomised Feasibility Trial
CONCLUSIONS: Randomisation to UHM, FHM, and PTF diets by opt-out consent was acceptable to parents and clinical teams, associated with safe growth profiles and no significant differences in body composition. Our data provide justification to proceed to a larger RCT.PMID:38091960 | DOI:10.1159/000535498 (Source: Neonatology)
Source: Neonatology - December 13, 2023 Category: Perinatology & Neonatology Authors: Luke Mills Karyn E Chappell Robby Emsley Afshin Alavi Izabela Andrzejewska Shalini Santhakumaran Richard Nicholl John Chang Sabita Uthaya Neena Modi Source Type: research

Preterm Formula, Fortified or Unfortified Human Milk for Very Preterm Infants, the PREMFOOD Study: A Parallel Randomised Feasibility Trial
CONCLUSIONS: Randomisation to UHM, FHM, and PTF diets by opt-out consent was acceptable to parents and clinical teams, associated with safe growth profiles and no significant differences in body composition. Our data provide justification to proceed to a larger RCT.PMID:38091960 | DOI:10.1159/000535498 (Source: Neonatology)
Source: Neonatology - December 13, 2023 Category: Perinatology & Neonatology Authors: Luke Mills Karyn E Chappell Robby Emsley Afshin Alavi Izabela Andrzejewska Shalini Santhakumaran Richard Nicholl John Chang Sabita Uthaya Neena Modi Source Type: research