Effect of Neonatal Unit Interventions Designed to Increase Breastfeeding in Preterm Infants: An Overview of Systematic Reviews
CONCLUSION: There is ample evidence to support investment in KMC, avoidance of bottles during breastfeed establishment, cup feeding, and QI bundles targeted at better supporting breastfeeding in neonatal units to increase prevalence of breastfeeding in preterm infants and promote equal access to breastmilk. Stratifying effects by relevant subgroups is a research priority.PMID:38513630 | DOI:10.1159/000536660 (Source: Neonatology)
Source: Neonatology - March 21, 2024 Category: Perinatology & Neonatology Authors: Cathie Hilditch Alice R Rumbold Amy Keir Philippa Middleton Judith Gomersall Source Type: research

Effect of Neonatal Unit Interventions Designed to Increase Breastfeeding in Preterm Infants: An Overview of Systematic Reviews
CONCLUSION: There is ample evidence to support investment in KMC, avoidance of bottles during breastfeed establishment, cup feeding, and QI bundles targeted at better supporting breastfeeding in neonatal units to increase prevalence of breastfeeding in preterm infants and promote equal access to breastmilk. Stratifying effects by relevant subgroups is a research priority.PMID:38513630 | DOI:10.1159/000536660 (Source: Neonatology)
Source: Neonatology - March 21, 2024 Category: Perinatology & Neonatology Authors: Cathie Hilditch Alice R Rumbold Amy Keir Philippa Middleton Judith Gomersall Source Type: research

Less Invasive Surfactant Administration Compared to Intubation, Surfactant, Rapid Extubation Method in Preterm Neonates: An Umbrella Review
CONCLUSIONS: All the included systematic reviews and meta-analyses reported LISA to be more effective than INSURE in terms of need for mechanical ventilation and death or BPD. However, the quality of the published systematic reviews has been mostly deficient. Future systematic reviews should focus on reporting quality.PMID:38503270 | DOI:10.1159/000537903 (Source: Neonatology)
Source: Neonatology - March 19, 2024 Category: Perinatology & Neonatology Authors: Ilari Kuitunen Kati R äsänen Source Type: research

Breastfeeding the Infant Born Premature: Opportunity and Optimism
Neonatology. 2024 Mar 19:1-3. doi: 10.1159/000537899. Online ahead of print.NO ABSTRACTPMID:38503275 | DOI:10.1159/000537899 (Source: Neonatology)
Source: Neonatology - March 19, 2024 Category: Perinatology & Neonatology Authors: Malika D Shah Daniel T Robinson Source Type: research

Less Invasive Surfactant Administration Compared to Intubation, Surfactant, Rapid Extubation Method in Preterm Neonates: An Umbrella Review
CONCLUSIONS: All the included systematic reviews and meta-analyses reported LISA to be more effective than INSURE in terms of need for mechanical ventilation and death or BPD. However, the quality of the published systematic reviews has been mostly deficient. Future systematic reviews should focus on reporting quality.PMID:38503270 | DOI:10.1159/000537903 (Source: Neonatology)
Source: Neonatology - March 19, 2024 Category: Perinatology & Neonatology Authors: Ilari Kuitunen Kati R äsänen Source Type: research

Breastfeeding the Infant Born Premature: Opportunity and Optimism
Neonatology. 2024 Mar 19:1-3. doi: 10.1159/000537899. Online ahead of print.NO ABSTRACTPMID:38503275 | DOI:10.1159/000537899 (Source: Neonatology)
Source: Neonatology - March 19, 2024 Category: Perinatology & Neonatology Authors: Malika D Shah Daniel T Robinson Source Type: research

Less Invasive Surfactant Administration Compared to Intubation, Surfactant, Rapid Extubation Method in Preterm Neonates: An Umbrella Review
CONCLUSIONS: All the included systematic reviews and meta-analyses reported LISA to be more effective than INSURE in terms of need for mechanical ventilation and death or BPD. However, the quality of the published systematic reviews has been mostly deficient. Future systematic reviews should focus on reporting quality.PMID:38503270 | DOI:10.1159/000537903 (Source: Neonatology)
Source: Neonatology - March 19, 2024 Category: Perinatology & Neonatology Authors: Ilari Kuitunen Kati R äsänen Source Type: research

Breastfeeding the Infant Born Premature: Opportunity and Optimism
Neonatology. 2024 Mar 19:1-3. doi: 10.1159/000537899. Online ahead of print.NO ABSTRACTPMID:38503275 | DOI:10.1159/000537899 (Source: Neonatology)
Source: Neonatology - March 19, 2024 Category: Perinatology & Neonatology Authors: Malika D Shah Daniel T Robinson Source Type: research

Elevated Urine Hyaluronan Concentrations Are Associated with an Unfavorable Respiratory Outcome in Preterm Neonates at 40 Weeks Postmenstrual Age
CONCLUSION: Neonatal urine screening for HA could identify infants at risk for death or need for respiratory support at term-corrected age (40 weeks PMA). The relationship between elevated HA at 1 week and an unfavorable 40 week outcome was stronger in infants with lower GA.PMID:38484718 | DOI:10.1159/000535185 (Source: Neonatology)
Source: Neonatology - March 14, 2024 Category: Perinatology & Neonatology Authors: Peter Mathew MacFarlane Zhengyi Chen Nori Minich Catherine Ann Mayer Richard John Martin Juliann Marie Di Fiore Thomas Michael Raffay Anna Maria Hibbs Source Type: research

Elevated Urine Hyaluronan Concentrations Are Associated with an Unfavorable Respiratory Outcome in Preterm Neonates at 40 Weeks Postmenstrual Age
CONCLUSION: Neonatal urine screening for HA could identify infants at risk for death or need for respiratory support at term-corrected age (40 weeks PMA). The relationship between elevated HA at 1 week and an unfavorable 40 week outcome was stronger in infants with lower GA.PMID:38484718 | DOI:10.1159/000535185 (Source: Neonatology)
Source: Neonatology - March 14, 2024 Category: Perinatology & Neonatology Authors: Peter Mathew MacFarlane Zhengyi Chen Nori Minich Catherine Ann Mayer Richard John Martin Juliann Marie Di Fiore Thomas Michael Raffay Anna Maria Hibbs Source Type: research

Elevated Urine Hyaluronan Concentrations Are Associated with an Unfavorable Respiratory Outcome in Preterm Neonates at 40 Weeks Postmenstrual Age
CONCLUSION: Neonatal urine screening for HA could identify infants at risk for death or need for respiratory support at term-corrected age (40 weeks PMA). The relationship between elevated HA at 1 week and an unfavorable 40 week outcome was stronger in infants with lower GA.PMID:38484718 | DOI:10.1159/000535185 (Source: Neonatology)
Source: Neonatology - March 14, 2024 Category: Perinatology & Neonatology Authors: Peter Mathew MacFarlane Zhengyi Chen Nori Minich Catherine Ann Mayer Richard John Martin Juliann Marie Di Fiore Thomas Michael Raffay Anna Maria Hibbs Source Type: research

Elevated Urine Hyaluronan Concentrations Are Associated with an Unfavorable Respiratory Outcome in Preterm Neonates at 40 Weeks Postmenstrual Age
CONCLUSION: Neonatal urine screening for HA could identify infants at risk for death or need for respiratory support at term-corrected age (40 weeks PMA). The relationship between elevated HA at 1 week and an unfavorable 40 week outcome was stronger in infants with lower GA.PMID:38484718 | DOI:10.1159/000535185 (Source: Neonatology)
Source: Neonatology - March 14, 2024 Category: Perinatology & Neonatology Authors: Peter Mathew MacFarlane Zhengyi Chen Nori Minich Catherine Ann Mayer Richard John Martin Juliann Marie Di Fiore Thomas Michael Raffay Anna Maria Hibbs Source Type: research

Temporal Trends in Severe Brain Injury and Associated Outcomes in Very Preterm Infants
CONCLUSION: Neither the rates of SBI nor its associated composite outcome of death or NDI improved over time. A notable proportion of preterm infants with SBI faced redirection of care and subsequent mortality, while most survivors exhibited adverse neurodevelopmental challenges. The development of better therapeutic interventions is imperative to improve outcomes for these vulnerable infants.PMID:38471459 | DOI:10.1159/000537801 (Source: Neonatology)
Source: Neonatology - March 12, 2024 Category: Perinatology & Neonatology Authors: Abdul Razak Emily Johnston Alice Stewart Marissa A T Clark Penelope Stevens Margaret Charlton Flora Wong C McDonald Rod W Hunt Suzanne Miller Atul Malhotra Source Type: research

Temporal Trends in Severe Brain Injury and Associated Outcomes in Very Preterm Infants
CONCLUSION: Neither the rates of SBI nor its associated composite outcome of death or NDI improved over time. A notable proportion of preterm infants with SBI faced redirection of care and subsequent mortality, while most survivors exhibited adverse neurodevelopmental challenges. The development of better therapeutic interventions is imperative to improve outcomes for these vulnerable infants.PMID:38471459 | DOI:10.1159/000537801 (Source: Neonatology)
Source: Neonatology - March 12, 2024 Category: Perinatology & Neonatology Authors: Abdul Razak Emily Johnston Alice Stewart Marissa A T Clark Penelope Stevens Margaret Charlton Flora Wong C McDonald Rod W Hunt Suzanne Miller Atul Malhotra Source Type: research

Positive Pressure Ventilation in Preterm Infants in the Delivery Room: A Review of Current Practices, Challenges, and Emerging Technologies
Neonatology. 2024 Mar 11:1-10. doi: 10.1159/000537800. Online ahead of print.ABSTRACTBACKGROUND: A major proportion of preterm neonates require positive pressure ventilation (PPV) immediately after delivery. PPV may be administered through a face mask (FM) or nasal prongs. Current literature indicates that either of these are associated with similar outcomes.SUMMARY: Nonetheless, FM remains the most utilized and the best choice. However, most available FM sizes are too large for extremely preterm infants, which leads to mask leak and ineffective PPV. Challenges to providing effective PPV include poor respiratory drive, com...
Source: Neonatology - March 11, 2024 Category: Perinatology & Neonatology Authors: Shivashankar Diggikar Viraraghavan V Ramaswamy Jenny Koo Arun Prasath Georg M Schm ölzer Source Type: research