Publisher Correction: The neuroanatomical–functional paradox in spinal cord injury
Nature Reviews Neurology, Published online: 08 August 2023; doi:10.1038/s41582-023-00865-4Publisher Correction: The neuroanatomical–functional paradox in spinal cord injury (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - August 8, 2023 Category: Neurology Authors: Karim Fouad Phillip G. Popovich Marcel A. Kopp Jan M. Schwab Source Type: research
Redefining cerebral palsies as a diverse group of neurodevelopmental disorders with genetic aetiology
Nature Reviews Neurology, Published online: 03 August 2023; doi:10.1038/s41582-023-00847-6The diagnosis of cerebral palsy is currently made on clinical observations only and does not consider aetiology or pathology. Here, van Eyk and colleagues review the current state of genomic testing in cerebral palsy and highlight the benefits of a ‘genotype-first’ approach for this group of disorders. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - August 3, 2023 Category: Neurology Authors: Clare L. van Eyk Michael C. Fahey Jozef Gecz Source Type: research
Highlights from AAIC 2023
Nature Reviews Neurology, Published online: 03 August 2023; doi:10.1038/s41582-023-00858-3The 2023 Alzheimer’s Association International Conference (AAIC) was held in Amsterdam, Netherlands on the 16–20 July 2023. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - August 3, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
Finger-prick blood test for Alzheimer disease
Nature Reviews Neurology, Published online: 01 August 2023; doi:10.1038/s41582-023-00857-4Biomarkers for Alzheimer disease can be measured from finger-prick blood samples, according to new findings presented at AAIC 2023. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - August 1, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
Nutritional and metabolic factors in amyotrophic lateral sclerosis
Nature Reviews Neurology, Published online: 27 July 2023; doi:10.1038/s41582-023-00845-8Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease classically thought to impact the motor system, but research is now investigating the contribution of non-motor symptoms. Here, the authors explore evidence that highlights the extent to which nutrition and metabolism might contribute to ALS pathogenesis, and discuss the effectiveness of modifying energy balance in ALS. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 27, 2023 Category: Neurology Authors: Albert Ludolph Luc Dupuis Edward Kasarskis Frederik Steyn Shyuan Ngo Christopher McDermott Source Type: research
New CRISPR-based strategies for Alzheimer disease
Nature Reviews Neurology, Published online: 25 July 2023; doi:10.1038/s41582-023-00856-5New findings announced at AAIC 2023 demonstrate the potential of CRISPR-based therapies for Alzheimer disease. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 25, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
New consensus guidelines on vaccination in multiple sclerosis
Nature Reviews Neurology, Published online: 25 July 2023; doi:10.1038/s41582-023-00854-7The European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and European Academy of Neurology (EAN) joint consensus statement on vaccination in people with multiple sclerosis provides highly relevant clinical guidance on immunization strategies in today’s era of effective immunotherapies. Nevertheless, several open questions remain to be addressed. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 25, 2023 Category: Neurology Authors: Uwe K. Zettl Paulus S. Rommer Source Type: research
The 5-HT1F receptor as the target of ditans in migraine — from bench to bedside
Nature Reviews Neurology, Published online: 12 July 2023; doi:10.1038/s41582-023-00842-xDitans are a recently developed drug class for the treatment of acute migraine. In this Review, the authors provide an overview of ditan development, from the initial rationale to the clinical studies that led to the recent FDA approval of the first ditan. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 12, 2023 Category: Neurology Authors: Dimos D. Mitsikostas Christian Waeber Margarita Sanchez-del-Rio Bianca Raffaelli H åkan Ashina Antoinette Maassen van den Brink Anna Andreou Patricia Pozo-Rosich Alan Rapoport Messoud Ashina Michael A. Moskowitz Source Type: research
Implications of immunometabolism for smouldering MS pathology and therapy
Nature Reviews Neurology, Published online: 10 July 2023; doi:10.1038/s41582-023-00839-6Smouldering inflammation encompasses all non-relapsing aspects of inflammatory pathobiology in multiple sclerosis. Here, Bittner and colleagues describe the mechanisms that underlie CNS-compartmentalized smouldering inflammation and review evidence indicating that immunometabolic reprogramming driven by the CNS tissue microenvironment shapes these inflammatory responses. Potential treatments are also discussed. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 10, 2023 Category: Neurology Authors: Stefan Bittner Katrin Pape Luisa Klotz Frauke Zipp Source Type: research
Electrophysiology test for early ALS diagnosis
Nature Reviews Neurology, Published online: 04 July 2023; doi:10.1038/s41582-023-00850-xElectrophysiology test for early ALS diagnosis (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 4, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
Early microbiome changes in neurodegenerative disease
Nature Reviews Neurology, Published online: 04 July 2023; doi:10.1038/s41582-023-00848-5Gut microbiome changes are present in both preclinical Alzheimer disease and prodromal Parkinson disease, new research indicates. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 4, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
Disease-specific modifications of tau protein
Nature Reviews Neurology, Published online: 04 July 2023; doi:10.1038/s41582-023-00851-wDisease-specific modifications of tau protein (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 4, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
A biomarker for mild cognitive impairment
Nature Reviews Neurology, Published online: 04 July 2023; doi:10.1038/s41582-023-00849-4A biomarker for mild cognitive impairment (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 4, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
Fatty acids might slow ALS progression
Nature Reviews Neurology, Published online: 04 July 2023; doi:10.1038/s41582-023-00852-9Fatty acids might slow ALS progression (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 4, 2023 Category: Neurology Authors: Lisa Kiani Source Type: research
Meningeal inflammation as a driver of cortical grey matter pathology and clinical progression in multiple sclerosis
Nature Reviews Neurology, Published online: 03 July 2023; doi:10.1038/s41582-023-00838-7Growing evidence indicates a central role for meningeal inflammation in driving multiple sclerosis (MS) pathology. In this Review, the authors summarize current knowledge regarding structural, cellular and molecular changes to the meninges in MS and discuss the clinical and therapeutic implications. (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - July 3, 2023 Category: Neurology Authors: Roberta Magliozzi Owain W. Howell Massimiliano Calabrese Richard Reynolds Source Type: research
