VIP cortical conductors set the tone for chronic pain
Nature Neuroscience 20, 1037 (2017).
doi:10.1038/nn.4609
Authors: Erika K Harding & Michael W Salter
Loss of inhibition in a circuit in the primary somatosensory cortex that controls the activity of layer 5 neurons drives pain hypersensitivity. Restoring this inhibition resets the inhibitory–excitatory balance, producing analgesia. (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 26, 2017 Category: Neuroscience Authors: Erika K Harding Michael W Salter Tags: News and Views Source Type: research
Helping EGFR inhibition to block cancer
Nature Neuroscience 20, 1035 (2017).
doi:10.1038/nn.4605
Authors: Rolf Warta & Christel Herold-Mende
Effectiveness of EGFR treatment is impaired through an early adaptive response. TNF–JNK–Axl–ERK signaling contributes to this primary resistance to EGFR inhibition and might serve as novel target to improve EGFR inhibition. (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 26, 2017 Category: Neuroscience Authors: Rolf Warta Christel Herold-Mende Tags: News and Views Source Type: research
High-dimensional, single-cell characterization of the brain's immune compartment
Nature Neuroscience 20, 1300 (2017).
doi:10.1038/nn.4610
Authors: Ben Korin, Tamar L Ben-Shaanan, Maya Schiller, Tania Dubovik, Hilla Azulay-Debby, Nadia T Boshnak, Tamar Koren & Asya Rolls (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 24, 2017 Category: Neuroscience Authors: Ben Korin Tamar L Ben-Shaanan Maya Schiller Tania Dubovik Hilla Azulay-Debby Nadia T Boshnak Tamar Koren Asya Rolls Tags: Resource Source Type: research
Functional dissection of signal and noise in MT and LIP during decision-making
Nature Neuroscience 20, 1285 (2017).
doi:10.1038/nn.4611
Authors: Jacob L Yates, Il Memming Park, Leor N Katz, Jonathan W Pillow & Alexander C Huk (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 24, 2017 Category: Neuroscience Authors: Jacob L Yates Il Memming Park Leor N Katz Jonathan W Pillow Alexander C Huk Tags: Article Source Type: research
Necroptosis activation in Alzheimer's disease
Nature Neuroscience 20, 1236 (2017).
doi:10.1038/nn.4608
Authors: Antonella Caccamo, Caterina Branca, Ignazio S Piras, Eric Ferreira, Matthew J Huentelman, Winnie S Liang, Ben Readhead, Joel T Dudley, Elizabeth E Spangenberg, Kim N Green, Ramona Belfiore, Wendy Winslow & Salvatore Oddo (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 24, 2017 Category: Neuroscience Authors: Antonella Caccamo Caterina Branca Ignazio S Piras Eric Ferreira Matthew J Huentelman Winnie S Liang Ben Readhead Joel T Dudley Elizabeth E Spangenberg Kim N Green Ramona Belfiore Wendy Winslow Salvatore Oddo Tags: Article Source Type: research
A circuit-based mechanism underlying familiarity signaling and the preference for novelty
Nature Neuroscience 20, 1260 (2017).
doi:10.1038/nn.4607
Authors: Susanna Molas, Rubing Zhao-Shea, Liwang Liu, Steven R DeGroot, Paul D Gardner & Andrew R Tapper (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 17, 2017 Category: Neuroscience Authors: Susanna Molas Rubing Zhao-Shea Liwang Liu Steven R DeGroot Paul D Gardner Andrew R Tapper Tags: Article Source Type: research
C9orf72 expansion disrupts ATM-mediated chromosomal break repair
Nature Neuroscience 20, 1225 (2017).
doi:10.1038/nn.4604
Authors: Callum Walker, Saul Herranz-Martin, Evangelia Karyka, Chunyan Liao, Katherine Lewis, Waheba Elsayed, Vera Lukashchuk, Shih-Chieh Chiang, Swagat Ray, Padraig J Mulcahy, Mateusz Jurga, Ioannis Tsagakis, Tommaso Iannitti, Jayanth Chandran, Ian Coldicott, Kurt J De Vos, Mohamed K Hassan, Adrian Higginbottom, Pamela J Shaw, Guillaume M Hautbergue, Mimoun Azzouz & Sherif F El-Khamisy (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 17, 2017 Category: Neuroscience Authors: Callum Walker Saul Herranz-Martin Evangelia Karyka Chunyan Liao Katherine Lewis Waheba Elsayed Vera Lukashchuk Shih-Chieh Chiang Swagat Ray Padraig J Mulcahy Mateusz Jurga Ioannis Tsagakis Tommaso Iannitti Jayanth Chandran Ian Coldicott Kurt J De Vos Moha Tags: Article Source Type: research
Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder
Nature Neuroscience 20, 1217 (2017).
doi:10.1038/nn.4598
Authors: Elaine T Lim, Mohammed Uddin, Silvia De Rubeis, Yingleong Chan, Anne S Kamumbu, Xiaochang Zhang, Alissa M D'Gama, Sonia N Kim, Robert Sean Hill, Arthur P Goldberg, Christopher Poultney, Nancy J Minshew, Itaru Kushima, Branko Aleksic, Norio Ozaki, Mara Parellada, Celso Arango, Maria J Penzol, Angel Carracedo, Alexander Kolevzon, Christina M Hultman, Lauren A Weiss, Menachem Fromer, Andreas G Chiocchetti, Christine M Freitag, George M Church, Stephen W Scherer, Joseph D Buxbaum & Christopher A Walsh (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 17, 2017 Category: Neuroscience Authors: Elaine T Lim Mohammed Uddin Silvia De Rubeis Yingleong Chan Anne S Kamumbu Xiaochang Zhang Alissa M D'Gama Sonia N Kim Robert Sean Hill Arthur P Goldberg Christopher Poultney Nancy J Minshew Itaru Kushima Branko Aleksic Norio Ozaki Mara Parellada Celso Ar Tags: Article Source Type: research
Gut microbiota is critical for the induction of chemotherapy-induced pain
Nature Neuroscience 20, 1213 (2017).
doi:10.1038/nn.4606
Authors: Shiqian Shen, Grewo Lim, Zerong You, Weihua Ding, Peigen Huang, Chongzhao Ran, Jason Doheny, Peter Caravan, Samuel Tate, Kun Hu, Hyangin Kim, Michael McCabe, Bo Huang, Zhongcong Xie, Douglas Kwon, Lucy Chen & Jianren Mao
Chemotherapy-induced pain is a dose-limiting condition that affects 30% of patients undergoing chemotherapy. We found that gut microbiota promotes the development of chemotherapy-induced mechanical hyperalgesia. Oxaliplatin-induced mechanical hyperalgesia was reduced in germ-free mice and in mice pretreated with antibiotics. Rest...
Source: Nature Neuroscience - July 17, 2017 Category: Neuroscience Authors: Shiqian Shen Grewo Lim Zerong You Weihua Ding Peigen Huang Chongzhao Ran Jason Doheny Peter Caravan Samuel Tate Kun Hu Hyangin Kim Michael McCabe Bo Huang Zhongcong Xie Douglas Kwon Lucy Chen Jianren Mao Tags: Brief Communication Source Type: research
Neural reactivations during sleep determine network credit assignment
Nature Neuroscience 20, 1277 (2017).
doi:10.1038/nn.4601
Authors: Tanuj Gulati, Ling Guo, Dhakshin S Ramanathan, Anitha Bodepudi & Karunesh Ganguly (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 10, 2017 Category: Neuroscience Authors: Tanuj Gulati Ling Guo Dhakshin S Ramanathan Anitha Bodepudi Karunesh Ganguly Tags: Article Source Type: research
A causal account of the brain network computations underlying strategic social behavior
Nature Neuroscience 20, 1142 (2017).
doi:10.1038/nn.4602
Authors: Christopher A Hill, Shinsuke Suzuki, Rafael Polania, Marius Moisa, John P O'Doherty & Christian C Ruff (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 10, 2017 Category: Neuroscience Authors: Christopher A Hill Shinsuke Suzuki Rafael Polania Marius Moisa John P O'Doherty Christian C Ruff Tags: Article Source Type: research
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
Nature Neuroscience 20, 1162 (2017).
doi:10.1038/nn.4597
Authors: Thais F Galatro, Inge R Holtman, Antonio M Lerario, Ilia D Vainchtein, Nieske Brouwer, Paula R Sola, Mariana M Veras, Tulio F Pereira, Renata E P Leite, Thomas Möller, Paul D Wes, Mari C Sogayar, Jon D Laman, Wilfred den Dunnen, Carlos A Pasqualucci, Sueli M Oba-Shinjo, Erik W G M Boddeke, Suely K N Marie & Bart J L Eggen (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 3, 2017 Category: Neuroscience Authors: Thais F Galatro Inge R Holtman Antonio M Lerario Ilia D Vainchtein Nieske Brouwer Paula R Sola Mariana M Veras Tulio F Pereira Renata E P Leite Thomas M รถ ller Paul D Wes Mari C Sogayar Jon D Laman Wilfred den Dunnen Carlos A Pasqualucci Sueli M Oba-Shin Tags: Resource Source Type: research
Reorganization of corticospinal output during motor learning
Nature Neuroscience 20, 1133 (2017).
doi:10.1038/nn.4596
Authors: Andrew J Peters, Jun Lee, Nathan G Hedrick, Keelin O'Neil & Takaki Komiyama (Source: Nature Neuroscience)
Source: Nature Neuroscience - July 3, 2017 Category: Neuroscience Authors: Andrew J Peters Jun Lee Nathan G Hedrick Keelin O'Neil Takaki Komiyama Tags: Article Source Type: research
Addendum: A viral strategy for targeting and manipulating interneurons across vertebrate species
Nature Neuroscience 20, 1033 (2017).
doi:10.1038/nn0717-1033d
Author: Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi, Lihua Guo, Qing Xu, Runpeng Liu, Congyi Lu, Jianhua Chu, Michael C Avery, Mohammad S Rashid, Myungin Baek, Amanda L Jacob, Gordon B Smith, Daniel E Wilson, Georg Kosche, Illya Kruglikov, Tomasz Rusielewicz, Vibhakar C Kotak, Todd M Mowery, Stewart A Anderson, Edward M Callaway, Jeremy S Dasen, David Fitzpatrick, Valentina Fossati, Michael A Long, Scott Noggle, John H Reynolds, Dan H Sanes, Bernardo Rudy, Guoping Feng & Gord Fishell (Source: Nature Neuroscience)
Source: Nature Neuroscience - June 27, 2017 Category: Neuroscience Authors: Jordane Dimidschstein Qian Chen Robin Tremblay Stephanie L Rogers Giuseppe-Antonio Saldi Lihua Guo Qing Xu Runpeng Liu Congyi Lu Jianhua Chu Michael C Avery Mohammad S Rashid Myungin Baek Amanda L Jacob Gordon B Smith Daniel E Wilson Georg Kosche Illya Kr Tags: Addendum Source Type: research
Corrigendum: A viral strategy for targeting and manipulating interneurons across vertebrate species
Nature Neuroscience 20, 1033 (2017).
doi:10.1038/nn0717-1033c
Author: Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi, Lihua Guo, Qing Xu, Runpeng Liu, Congyi Lu, Jianhua Chu, Michael C Avery, Mohammad S Rashid, Myungin Baek, Amanda L Jacob, Gordon B Smith, Daniel E Wilson, Georg Kosche, Illya Kruglikov, Tomasz Rusielewicz, Vibhakar C Kotak, Todd M Mowery, Stewart A Anderson, Edward M Callaway, Jeremy S Dasen, David Fitzpatrick, Valentina Fossati, Michael A Long, Scott Noggle, John H Reynolds, Dan H Sanes, Bernardo Rudy, Guoping Feng & Gord Fishell (Source: Nature Neuroscience)
Source: Nature Neuroscience - June 27, 2017 Category: Neuroscience Authors: Jordane Dimidschstein Qian Chen Robin Tremblay Stephanie L Rogers Giuseppe-Antonio Saldi Lihua Guo Qing Xu Runpeng Liu Congyi Lu Jianhua Chu Michael C Avery Mohammad S Rashid Myungin Baek Amanda L Jacob Gordon B Smith Daniel E Wilson Georg Kosche Illya Kr Tags: Corrigendum Source Type: research
