The road to precision psychiatry: translating genetics into disease mechanisms
Nature Neuroscience 19, 1397 (2016).
doi:10.1038/nn.4409
Authors: Michael J Gandal, Virpi Leppa, Hyejung Won, Neelroop N Parikshak & Daniel H Geschwind (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 25, 2016 Category: Neuroscience Authors: Michael J Gandal Virpi Leppa Hyejung Won Neelroop N Parikshak Daniel H Geschwind Tags: Review Source Type: research
The origin and natural history of autism spectrum disorders
Nature Neuroscience 19, 1390 (2016).
doi:10.1038/nn.4427
Author: James C Harris
Refined social phenotyping of syndromic and idiopathic forms of autism, combined with advances in genetics, animal models of syndromes and brain imaging, may facilitate discovery of shared brain mechanisms that will lead to new treatments. The reversal of social deficits in animal models is promising for eventual translation into therapeutics. (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 25, 2016 Category: Neuroscience Authors: James C Harris Tags: Commentary Source Type: research
Psychiatric distress in animals versus animal models of psychiatric distress
Nature Neuroscience 19, 1387 (2016).
doi:10.1038/nn.4397
Author: Robert M Sapolsky (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 25, 2016 Category: Neuroscience Authors: Robert M Sapolsky Tags: Commentary Source Type: research
On being a circuit psychiatrist
Nature Neuroscience 19, 1385 (2016).
doi:10.1038/nn.4419
Author: Joshua A Gordon (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 25, 2016 Category: Neuroscience Authors: Joshua A Gordon Tags: Commentary Source Type: research
Back to basics: luring industry back into neuroscience
Nature Neuroscience 19, 1383 (2016).
doi:10.1038/nn.4429
Author: Steven E Hyman (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 25, 2016 Category: Neuroscience Authors: Steven E Hyman Tags: Correspondence Source Type: research
Focus on psychiatric disorders
Nature Neuroscience 19, 1381 (2016).
doi:10.1038/nn.4434
Nature Neuroscience presents a Focus issue highlighting progress in basic and clinical sciences advancing mental health research. (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 25, 2016 Category: Neuroscience Tags: Editorial Source Type: research
The brain adapts to dishonesty
Nature Neuroscience 19, 1727 (2016).
doi:10.1038/nn.4426
Authors: Neil Garrett, Stephanie C Lazzaro, Dan Ariely & Tali Sharot (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 23, 2016 Category: Neuroscience Authors: Neil Garrett Stephanie C Lazzaro Dan Ariely Tali Sharot Tags: Article Source Type: research
Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
Nature Neuroscience 19, 1619 (2016).
doi:10.1038/nn.4428
Authors: Anusha Mishra, James P Reynolds, Yang Chen, Alexander V Gourine, Dmitri A Rusakov & David Attwell (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 23, 2016 Category: Neuroscience Authors: Anusha Mishra James P Reynolds Yang Chen Alexander V Gourine Dmitri A Rusakov David Attwell Tags: Article Source Type: research
Gravity orientation tuning in macaque anterior thalamus
Nature Neuroscience 19, 1566 (2016).
doi:10.1038/nn.4423
Authors: Jean Laurens, Byounghoon Kim, J David Dickman & Dora E Angelaki
Gravity may provide a ubiquitous allocentric reference to the brain's spatial orientation circuits. Here we describe neurons in the macaque anterior thalamus tuned to pitch and roll orientation relative to gravity, independently of visual landmarks. We show that individual cells exhibit two-dimensional tuning curves, with peak firing rates at a preferred vertical orientation. These results identify a thalamic pathway for gravity cues to influence perception, action and spatial cognit...
Source: Nature Neuroscience - October 23, 2016 Category: Neuroscience Authors: Jean Laurens Byounghoon Kim J David Dickman Dora E Angelaki Tags: Brief Communication Source Type: research
TRPA1 mediates sensation of the rate of temperature change in Drosophila larvae
Nature Neuroscience 20, 34 (2017).
doi:10.1038/nn.4416
Authors: Junjie Luo, Wei L Shen & Craig Montell (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 16, 2016 Category: Neuroscience Authors: Junjie Luo Wei L Shen Craig Montell Tags: Article Source Type: research
Organization of long-range inputs and outputs of frontal cortex for top-down control
Nature Neuroscience 19, 1733 (2016).
doi:10.1038/nn.4417
Authors: Siyu Zhang, Min Xu, Wei-Cheng Chang, Chenyan Ma, Johnny Phong Hoang Do, Daniel Jeong, Tiffany Lei, Jiang Lan Fan & Yang Dan (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 16, 2016 Category: Neuroscience Authors: Siyu Zhang Min Xu Wei-Cheng Chang Chenyan Ma Johnny Phong Hoang Do Daniel Jeong Tiffany Lei Jiang Lan Fan Yang Dan Tags: Resource Source Type: research
Synaptic scaling rule preserves excitatory –inhibitory balance and salient neuronal network dynamics
Nature Neuroscience 19, 1690 (2016).
doi:10.1038/nn.4415
Authors: Jérémie Barral & Alex D Reyes (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 16, 2016 Category: Neuroscience Authors: J érémie Barral Alex D Reyes Tags: Article Source Type: research
Layer 4 fast-spiking interneurons filter thalamocortical signals during active somatosensation
Nature Neuroscience 19, 1647 (2016).
doi:10.1038/nn.4412
Authors: Jianing Yu, Diego A Gutnisky, S Andrew Hires & Karel Svoboda (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 16, 2016 Category: Neuroscience Authors: Jianing Yu Diego A Gutnisky S Andrew Hires Karel Svoboda Tags: Article Source Type: research
Antagonistic negative and positive neurons of the basolateral amygdala
Nature Neuroscience 19, 1636 (2016).
doi:10.1038/nn.4414
Authors: Joshua Kim, Michele Pignatelli, Sangyu Xu, Shigeyoshi Itohara & Susumu Tonegawa (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 16, 2016 Category: Neuroscience Authors: Joshua Kim Michele Pignatelli Sangyu Xu Shigeyoshi Itohara Susumu Tonegawa Tags: Article Source Type: research
Functional and structural underpinnings of neuronal assembly formation in learning
Nature Neuroscience 19, 1553 (2016).
doi:10.1038/nn.4418
Authors: Anthony Holtmaat & Pico Caroni (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 16, 2016 Category: Neuroscience Authors: Anthony Holtmaat Pico Caroni Tags: Review Source Type: research