Erratum: Reply to “Neutrophils are not required for resolution of acute gouty arthritis in mice”
Nature Medicine 23, 526 (2017).
doi:10.1038/nm0417-526b
Authors: Christiane Reinwald, Christine Schauer, Janka Zsófia Csepregi, Deborah Kienhöfer, Daniela Weidner, Marie Malissen, Attila Mocsai, Georg Schett, Martin Herrmann & Markus Hoffmann (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Christiane Reinwald Christine Schauer Janka Zs ófia Csepregi Deborah Kienh öfer Daniela Weidner Marie Malissen Attila Mocsai Georg Schett Martin Herrmann Markus Hoffmann Tags: Erratum Source Type: research
Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
Nature Medicine 23, 526 (2017).
doi:10.1038/nm0417-526a
Authors: Stephanus T Malherbe, Shubhada Shenai, Katharina Ronacher, Andre G Loxton, Gregory Dolganov, Magdalena Kriel, Tran Van, Ray Y Chen, James Warwick, Laura E Via, Taeksun Song, Myungsun Lee, Gary Schoolnik, Gerard Tromp, David Alland, Clifton E Barry, Jill Winter & Gerhard Walzl (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Stephanus T Malherbe Shubhada Shenai Katharina Ronacher Andre G Loxton Gregory Dolganov Magdalena Kriel Tran Van Ray Y Chen James Warwick Laura E Via Taeksun Song Myungsun Lee Gary Schoolnik Gerard Tromp David Alland Clifton E Barry Jill Winter Gerhard Wa Tags: Corrigendum Source Type: research
Untangling the role of mutant histone H3 in diffuse intrinsic pontine glioma
Nature Medicine 23, 413 (2017).
doi:10.1038/nm.4320
Author: Caretha L Creasy
New studies advance the mechanistic understanding of mutant histone H3 in diffuse intrinsic pontine glioma (DIPG) and demonstrate two epigenetic approaches, BET inhibition and EZH2 inhibition, as potential therapeutic strategies for DIPG. (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Caretha L Creasy Tags: News and Views Source Type: research
A mouse recapitulating APOL1-associated kidney disease
Nature Medicine 23, 411 (2017).
doi:10.1038/nm.4318
Authors: Cheryl A Winkler & George W Nelson
In a recent study, researchers generated a mouse model expressing variant APOL1 that recapitulates human kidney disease. Variant APOL1 leads to caspase-1-dependent pyroptosis, which opens the door for the development of new druggable targets to treat APOL1-mediated kidney disease. (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Cheryl A Winkler George W Nelson Tags: News and Views Source Type: research
Autoimmune T cell recognition of alternative-reading-frame-encoded peptides
Nature Medicine 23, 409 (2017).
doi:10.1038/nm.4317
Authors: Jiajie Wei & Jonathan W Yewdell
A recent study shows that a self-peptide generated in pancreatic islet beta cells through the translation of a noncanonical alternative reading frame in human insulin mRNA is recognized by both CD4+ and CD8+ T cells in type 1 diabetes. (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Jiajie Wei Jonathan W Yewdell Tags: News and Views Source Type: research
The Drug Repurposing Hub: a next-generation drug library and information resource
Nature Medicine 23, 405 (2017).
doi:10.1038/nm.4306
Authors: Steven M Corsello, Joshua A Bittker, Zihan Liu, Joshua Gould, Patrick McCarren, Jodi E Hirschman, Stephen E Johnston, Anita Vrcic, Bang Wong, Mariya Khan, Jacob Asiedu, Rajiv Narayan, Christopher C Mader, Aravind Subramanian & Todd R Golub (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Steven M Corsello Joshua A Bittker Zihan Liu Joshua Gould Patrick McCarren Jodi E Hirschman Stephen E Johnston Anita Vrcic Bang Wong Mariya Khan Jacob Asiedu Rajiv Narayan Christopher C Mader Aravind Subramanian Todd R Golub Tags: Correspondence Source Type: research
Correction
Nature Medicine 23, 404 (2017).
doi:10.1038/nm0417-404 (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Tags: Correction Source Type: research
A curious connection: Teasing apart the link between gut microbes and lung disease
Nature Medicine 23, 402 (2017).
doi:10.1038/nm0417-402
Author: Shraddha Chakradhar (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Shraddha Chakradhar Tags: News Source Type: research
Beyond the breath: Exploring sex differences in tuberculosis outside the lungs
Nature Medicine 23, 398 (2017).
doi:10.1038/nm0417-398
Author: Alla Katsnelson (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Alla Katsnelson Tags: News Source Type: research
Science over speed
Nature Medicine 23, 397 (2017).
doi:10.1038/nm.4325 (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Tags: Editorial Source Type: research
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor – neutralizing therapy in patients with inflammatory bowel disease
Nature Medicine 23, 579 (2017).
doi:10.1038/nm.4307
Authors: Nathaniel R West, Ahmed N Hegazy, Benjamin M J Owens, Samuel J Bullers, Bryan Linggi, Sofia Buonocore, Margherita Coccia, Dieter Görtz, Sébastien This, Krista Stockenhuber, Johanna Pott, Matthias Friedrich, Grigory Ryzhakov, Frédéric Baribaud, Carrie Brodmerkel, Constanze Cieluch, Nahid Rahman, Gerhard Müller-Newen, Raymond J Owens, Anja A Kühl, Kevin J Maloy, Scott E Plevy, Carolina Arancibia, Adam Bailey, Ellie Barnes, Beth Bird-Lieberman, Oliver Brain, Barbara Braden, Jane Collier, James East, Lucy Howarth, Satish Keshav, ...
Source: Nature Medicine - April 3, 2017 Category: General Medicine Authors: Nathaniel R West Ahmed N Hegazy Benjamin M J Owens Samuel J Bullers Bryan Linggi Sofia Buonocore Margherita Coccia Dieter G ö rtz S é bastien This Krista Stockenhuber Johanna Pott Matthias Friedrich Grigory Ryzhakov Fr é d é ric Baribaud Carrie Brodme Tags: Article Source Type: research
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor –neutralizing therapy in patients with inflammatory bowel disease
Nature Medicine 23, 579 (2017).
doi:10.1038/nm.4307
Authors: Nathaniel R West, Ahmed N Hegazy, Benjamin M J Owens, Samuel J Bullers, Bryan Linggi, Sofia Buonocore, Margherita Coccia, Dieter Görtz, Sébastien This, Krista Stockenhuber, Johanna Pott, Matthias Friedrich, Grigory Ryzhakov, Frédéric Baribaud, Carrie Brodmerkel, Constanze Cieluch, Nahid Rahman, Gerhard Müller-Newen, Raymond J Owens, Anja A Kühl, Kevin J Maloy, Scott E Plevy, Carolina Arancibia, Adam Bailey, Ellie Barnes, Beth Bird-Lieberman, Oliver Brain, Barbara Braden, Jane Collier, James East, Lucy Howarth, Satish Keshav, ...
Source: Nature Medicine - April 3, 2017 Category: Journals (General) Authors: Nathaniel R West Ahmed N Hegazy Benjamin M J Owens Samuel J Bullers Bryan Linggi Sofia Buonocore Margherita Coccia Dieter G örtz S ébastien This Krista Stockenhuber Johanna Pott Matthias Friedrich Grigory Ryzhakov Fr édéric Baribaud Carrie Brodmerkel Tags: Article Source Type: research
Refining strategies to translate genome editing to the clinic
Nature Medicine 23, 415 (2017).
doi:10.1038/nm.4313
Authors: Tatjana I Cornu, Claudio Mussolino & Toni Cathomen (Source: Nature Medicine)
Source: Nature Medicine - April 3, 2017 Category: Journals (General) Authors: Tatjana I Cornu Claudio Mussolino Toni Cathomen Tags: Review Source Type: research
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
Nature Medicine 23, 631 (2017).
doi:10.1038/nm.4297
Authors: Matthew D Lynes, Luiz O Leiria, Morten Lundh, Alexander Bartelt, Farnaz Shamsi, Tian Lian Huang, Hirokazu Takahashi, Michael F Hirshman, Christian Schlein, Alexandra Lee, Lisa A Baer, Francis J May, Fei Gao, Niven R Narain, Emily Y Chen, Michael A Kiebish, Aaron M Cypess, Matthias Blüher, Laurie J Goodyear, Gökhan S Hotamisligil, Kristin I Stanford & Yu-Hua Tseng
Brown adipose tissue (BAT) and beige adipose tissue combust fuels for heat production in adult humans, and so constitute an appealing target for the treatment of metabolic disorders...
Source: Nature Medicine - March 27, 2017 Category: General Medicine Authors: Matthew D Lynes Luiz O Leiria Morten Lundh Alexander Bartelt Farnaz Shamsi Tian Lian Huang Hirokazu Takahashi Michael F Hirshman Christian Schlein Alexandra Lee Lisa A Baer Francis J May Fei Gao Niven R Narain Emily Y Chen Michael A Kiebish Aaron M Cypess Tags: Letter Source Type: research
VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer
Nature Medicine 23, 551 (2017).
doi:10.1038/nm.4308
Authors: Jianjun Gao, John F Ward, Curtis A Pettaway, Lewis Z Shi, Sumit K Subudhi, Luis M Vence, Hao Zhao, Jianfeng Chen, Hong Chen, Eleni Efstathiou, Patricia Troncoso, James P Allison, Christopher J Logothetis, Ignacio I Wistuba, Manuel A Sepulveda, Jingjing Sun, Jennifer Wargo, Jorge Blando & Padmanee Sharma
To date, anti-CTLA-4 (ipilimumab) or anti-PD-1 (nivolumab) monotherapy has not been demonstrated to be of substantial clinical benefit in patients with prostate cancer. To identify additional immune-inhibitory pathways in the prostate-tumor microenviro...
Source: Nature Medicine - March 27, 2017 Category: General Medicine Authors: Jianjun Gao John F Ward Curtis A Pettaway Lewis Z Shi Sumit K Subudhi Luis M Vence Hao Zhao Jianfeng Chen Hong Chen Eleni Efstathiou Patricia Troncoso James P Allison Christopher J Logothetis Ignacio I Wistuba Manuel A Sepulveda Jingjing Sun Jennifer Warg Tags: Brief Communication Source Type: research
