Erratum: Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor – neutralizing therapy in patients with inflammatory bowel disease
Nature Medicine 23, 788 (2017). doi:10.1038/nm0617-788d Authors: Nathaniel R West, Ahmed N Hegazy, Benjamin M J Owens, Samuel J Bullers, Bryan Linggi, Sofia Buonocore, Margherita Coccia, Dieter Görtz, Sébastien This, Krista Stockenhuber, Johanna Pott, Matthias Friedrich, Grigory Ryzhakov, Frédéric Baribaud, Carrie Brodmerkel, Constanze Cieluch, Nahid Rahman, Gerhard Müller-Newen, Raymond J Owens, Anja A Kühl, Kevin J Maloy, Scott E Plevy, Satish Keshav, Simon P L Travis & Fiona Powrie (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Nathaniel R West Ahmed N Hegazy Benjamin M J Owens Samuel J Bullers Bryan Linggi Sofia Buonocore Margherita Coccia Dieter G ö rtz S é bastien This Krista Stockenhuber Johanna Pott Matthias Friedrich Grigory Ryzhakov Fr é d é ric Baribaud Carrie Brodme Tags: Erratum Source Type: research

Erratum: Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents
Nature Medicine 23, 788 (2017). doi:10.1038/nm0617-788c Authors: Nicole E Burma, Robert P Bonin, Heather Leduc-Pessah, Corey Baimel, Zoe F Cairncross, Michael Mousseau, Jhenkruthi Vijaya Shankara, Patrick L Stemkowski, Dinara Baimoukhametova, Jaideep S Bains, Michael C Antle, Gerald W Zamponi, Catherine M Cahill, Stephanie L Borgland, Yves DeKoninck & Tuan Trang (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Nicole E Burma Robert P Bonin Heather Leduc-Pessah Corey Baimel Zoe F Cairncross Michael Mousseau Jhenkruthi Vijaya Shankara Patrick L Stemkowski Dinara Baimoukhametova Jaideep S Bains Michael C Antle Gerald W Zamponi Catherine M Cahill Stephanie L Borgla Tags: Erratum Source Type: research

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Nature Medicine 23, 788 (2017). doi:10.1038/nm0617-788b Authors: Fara Brasó-Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist, Erika Francesch-Domenech, Darren A Plumb, Leila Zakka, Patrycja Gazinska, Gianmaria Liccardi, Pascal Meier, Albert Gris-Oliver, Maggie Chon U Cheang, Anna Perdrix-Rosell, Manar Shafat, Elodie Noël, Nirmesh Patel, Kristen McEachern, Maurizio Scaltriti, Pau Castel, Farzana Noor, Richard Buus, Sumi Mathew, Johnathan Watkins, Violeta Serra, Pierfrancesco Marra, Anita Grigoriadis & Andrew N Tutt (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Fara Bras ó -Maristany Simone Filosto Steven Catchpole Rebecca Marlow Jelmar Quist Erika Francesch-Domenech Darren A Plumb Leila Zakka Patrycja Gazinska Gianmaria Liccardi Pascal Meier Albert Gris-Oliver Maggie Chon U Cheang Anna Perdrix-Rosell Manar Sha Tags: Erratum Source Type: research

Corrigendum: SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia
Nature Medicine 23, 788 (2017). doi:10.1038/nm0617-788a Authors: Constanze Schneider, Thomas Oellerich, Hanna-Mari Baldauf, Sarah-Marie Schwarz, Dominique Thomas, Robert Flick, Hanibal Bohnenberger, Lars Kaderali, Lena Stegmann, Anjali Cremer, Margarethe Martin, Julian Lohmeyer, Martin Michaelis, Veit Hornung, Christoph Schliemann, Wolfgang E Berdel, Wolfgang Hartmann, Eva Wardelmann, Federico Comoglio, Martin-Leo Hansmann, Alexander F Yakunin, Gerd Geisslinger, Philipp Ströbel, Nerea Ferreirós, Hubert Serve, Oliver T Keppler & Jindrich Cinatl (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Constanze Schneider Thomas Oellerich Hanna-Mari Baldauf Sarah-Marie Schwarz Dominique Thomas Robert Flick Hanibal Bohnenberger Lars Kaderali Lena Stegmann Anjali Cremer Margarethe Martin Julian Lohmeyer Martin Michaelis Veit Hornung Christoph Schliemann W Tags: Corrigendum Source Type: research

Biology and evolution of poorly differentiated neuroendocrine tumors
Nature Medicine 23, 664 (2017). doi:10.1038/nm.4341 Authors: David S Rickman, Himisha Beltran, Francesca Demichelis & Mark A Rubin (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: David S Rickman Himisha Beltran Francesca Demichelis Mark A Rubin Tags: Perspective Source Type: research

The cannabis paradox: when age matters
Nature Medicine 23, 661 (2017). doi:10.1038/nm.4348 Authors: Andrés Ozaita & Ester Aso New evidence in mouse models reveals that exposure to Δ9-tetrahydrocannabinol (THC), the main psychoactive component in Cannabis sativa, might improve cognitive performance in aging animals. (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Andr é s Ozaita Ester Aso Tags: News and Views Source Type: research

Patrolling monocytes sense peripheral infection and induce cytokine-mediated neuronal dysfunction
Nature Medicine 23, 659 (2017). doi:10.1038/nm.4349 Authors: Josef Priller & Chotima Böttcher A new study reveals that virus-associated activation of a subset of circulating monocytes results in the release of the proinflammatory cytokine tumor necrosis factor (TNF)-α, which induces increased turnover of synapses in the brain and learning deficits in mice. (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Josef Priller Chotima B ö ttcher Tags: News and Views Source Type: research

A role for neutrophils in asthma exacerbations
Nature Medicine 23, 658 (2017). doi:10.1038/nm.4351 Author: William W Busse A recent study has found that rhinovirus-induced exacerbation of asthma is in part mediated by the release of neutrophil extracellular traps and double-stranded DNA by neutrophils in the airway. (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: William W Busse Tags: News and Views Source Type: research

Understanding cancer from the stem cells up
Nature Medicine 23, 656 (2017). doi:10.1038/nm.4353 Authors: Christopher A Eide & Brian J Druker A new study that uses an integrated single-cell transcriptomics approach to characterize cancer stem cell populations during treatment with molecularly targeted therapies offers insights into disease evolution and points to new therapeutic targets. (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Christopher A Eide Brian J Druker Tags: News and Views Source Type: research

Viral vanguard: Designing cancer-killing viruses to chase metastatic tumors
Nature Medicine 23, 652 (2017). doi:10.1038/nm0617-652 Author: Shraddha Chakradhar (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Shraddha Chakradhar Tags: News Source Type: research

Biased for benefit: Stimulating the world's most popular drug targets with more nuance
Nature Medicine 23, 649 (2017). doi:10.1038/nm0617-649 Author: Dyani Lewis (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Dyani Lewis Tags: News Source Type: research

Source code: Putting metagenomics to the test in the clinic
Nature Medicine 23, 645 (2017). doi:10.1038/nm0617-645 Author: Carrie Arnold (Source: Nature Medicine)
Source: Nature Medicine - June 6, 2017 Category: General Medicine Authors: Carrie Arnold Tags: News Source Type: research

Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells
Nature Medicine 23, 885 (2017). doi:10.1038/nm.4347 Authors: Anwesha Sanyal, Robbie B Mailliard, Charles R Rinaldo, Deena Ratner, Ming Ding, Yue Chen, Jennifer M Zerbato, Nicholas S Giacobbi, Narasimhan J Venkatachari, Bruce K Patterson, Amanda Chargin, Nicolas Sluis-Cremer & Phalguni Gupta (Source: Nature Medicine)
Source: Nature Medicine - May 29, 2017 Category: General Medicine Authors: Anwesha Sanyal Robbie B Mailliard Charles R Rinaldo Deena Ratner Ming Ding Yue Chen Jennifer M Zerbato Nicholas S Giacobbi Narasimhan J Venkatachari Bruce K Patterson Amanda Chargin Nicolas Sluis-Cremer Phalguni Gupta Tags: Technical Report Source Type: research

Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice
Nature Medicine 23, 869 (2017). doi:10.1038/nm.4343 Authors: Sabine Harlander, Désirée Schönenberger, Nora C Toussaint, Michael Prummer, Antonella Catalano, Laura Brandt, Holger Moch, Peter J Wild & Ian J Frew (Source: Nature Medicine)
Source: Nature Medicine - May 29, 2017 Category: General Medicine Authors: Sabine Harlander D é sir é e Sch ö nenberger Nora C Toussaint Michael Prummer Antonella Catalano Laura Brandt Holger Moch Peter J Wild Ian J Frew Tags: Article Source Type: research

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
Nature Medicine 23, 850 (2017). doi:10.1038/nm.4345 Authors: Hao Wu, Eduardo Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix, Gemma Xifra, Josep M Mercader, David Torrents, Rémy Burcelin, Wifredo Ricart, Rosie Perkins, José Manuel Fernàndez-Real & Fredrik Bäckhed (Source: Nature Medicine)
Source: Nature Medicine - May 22, 2017 Category: General Medicine Authors: Hao Wu Eduardo Esteve Valentina Tremaroli Muhammad Tanweer Khan Robert Caesar Louise Manner å s-Holm Marcus St å hlman Lisa M Olsson Matteo Serino Merc è Planas-F è lix Gemma Xifra Josep M Mercader David Torrents R é my Burcelin Wifredo Ricart Rosie Tags: Article Source Type: research