Nanoscale scythe cuts molecular tethers using mechanical forces
Nature, Published online: 10 April 2024; doi:10.1038/d41586-024-00909-9Nanoscale systems that release small molecules have potential therapeutic and industrial uses, but can result in low numbers of molecules reaching their target. A release system triggered by mechanical force offers a fresh approach. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Iwona Nierengarten Source Type: research
Scalable, high-quality 2D telluride nanosheets for energy and catalysis applications
Nature, Published online: 10 April 2024; doi:10.1038/d41586-024-01006-7An innovative solid-state lithiation strategy allows the exfoliation of layered transition-metal tellurides into nanosheets in an unprecedentedly short time, without sacrificing their quality. The observation of physical phenomena typically seen in highly crystalline TMT nanosheets opens the way to their use in applications such as batteries and micro-supercapacitors. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Source Type: research
Wildlife boost in African forests certified for sustainable logging
Nature, Published online: 10 April 2024; doi:10.1038/d41586-024-00878-zIs there a conservation benefit if tropical forests that are affected by logging gain certification from the Forest Stewardship Council? An analysis of the biodiversity outcomes in such tropical forests provides answers. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Julia E. Fa Source Type: research
Frans de Waal (1948–2024), primatologist who questioned the uniqueness of human minds
Nature, Published online: 10 April 2024; doi:10.1038/d41586-024-01071-yResearcher and prolific science communicator who laid bare the social lives of apes. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Andrew Whiten Source Type: research
How to supercharge cancer-fighting cells: give them stem cell skills
Nature, Published online: 10 April 2024; doi:10.1038/d41586-024-01043-2The bioengineered immune players called CAR T cells last longer and work better if pumped up with a large dose of a protein that makes them resemble stem cells. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Sara Reardon Source Type: research
Peter Higgs: science mourns giant of particle physics
Nature, Published online: 10 April 2024; doi:10.1038/d41586-024-01069-6The British physicist, who has died aged 94, predicted the existence of the Higgs boson in the 1960s. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Davide Castelvecchi Source Type: research
FOXO1 is a master regulator of memory programming in CAR T cells
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07300-8The transcription factor FOXO1 has a key role in human T cell memory, and manipulating FOXO1 expression could provide a way to enhance CAR T cell therapies by increasing CAR T cell persistence and antitumour activity. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Alexander E. Doan Katherine P. Mueller Andy Y. Chen Geoffrey T. Rouin Yingshi Chen Bence Daniel John Lattin Martina Markovska Brett Mozarsky Jose Arias-Umana Robert Hapke In-Young Jung Alice Wang Peng Xu Dorota Klysz Gabrielle Zuern Malek Bashti Patrick J Source Type: research
Necroptosis blockade prevents lung injury in severe influenza
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07265-8A newly developed RIPK3 inhibitor blocks necroptosis of lung cells, reduces lung inflammation and prevents mortality in a mouse model of influenza A virus infection. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Avishekh Gautam David F. Boyd Sameer Nikhar Ting Zhang Ioannis Siokas Lee-Ann Van de Velde Jessica Gaevert Victoria Meliopoulos Bikash Thapa Diego A. Rodriguez Kathy Q. Cai Chaoran Yin Daniel Schnepf Julius Beer Carly DeAntoneo Riley M. Williams Maria Shu Source Type: research
Bitter taste receptor activation by cholesterol and an intracellular tastant
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07253-yCryo-electron microscopy structures of the type 2 taste receptor TAS2R14 in complex with Ggust and Gi1 identify cholesterol as an orthosteric agonist and the bitter tastant cmpd28.1 as a positive allosteric modulator and agonist. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Yoojoong Kim Ryan H. Gumpper Yongfeng Liu D. Dewran Kocak Yan Xiong Can Cao Zhijie Deng Brian E. Krumm Manish K. Jain Shicheng Zhang Jian Jin Bryan L. Roth Source Type: research
Terahertz electric-field-driven dynamical multiferroicity in SrTiO3
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07175-9We demonstrate the emergence of magnetism induced by a terahertz electric field in SrTiO3. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: M. Basini M. Pancaldi B. Wehinger M. Udina V. Unikandanunni T. Tadano M. C. Hoffmann A. V. Balatsky S. Bonetti Source Type: research
A hybrid topological quantum state in an elemental solid
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07203-8A hybrid topological phase of matter is discovered in the simple elemental-solid arsenic and explored using tunnelling microscopy, photoemission spectroscopy and a theoretical analysis. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Md Shafayat Hossain Frank Schindler Rajibul Islam Zahir Muhammad Yu-Xiao Jiang Zi-Jia Cheng Qi Zhang Tao Hou Hongyu Chen Maksim Litskevich Brian Casas Jia-Xin Yin Tyler A. Cochran Mohammad Yahyavi Xian P. Yang Luis Balicas Guoqing Chang Weisheng Zhao Titu Source Type: research
Direct observation of a magnetic-field-induced Wigner crystal
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07212-7A magnetic-field-induced Wigner crystal in Bernal-stacked bilayer graphene was directly imaged using high-resolution scanning tunnelling microscopy and its structural properties as a function of electron density, magnetic field and temperature were examined. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Yen-Chen Tsui Minhao He Yuwen Hu Ethan Lake Taige Wang Kenji Watanabe Takashi Taniguchi Michael P. Zaletel Ali Yazdani Source Type: research
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07295-2Studies on the µ-opioid receptor using fluorescent labelling of intracellular residues and energy transfer experiments in the presence of different ligands with or without G-protein binding reveals conformational changes that correlate to ligand efficacy. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Jiawei Zhao Matthias Elgeti Evan S. O ’Brien Cec ília P. Sár Amal EI Daibani Jie Heng Xiaoou Sun Elizabeth White Tao Che Wayne L. Hubbell Brian K. Kobilka Chunlai Chen Source Type: research
FSC-certified forest management benefits large mammals compared to non-FSC
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07257-8Camera-trap images of 55 mammal species in 14 logging concessions in western equatorial Africa reveal greater animal encounter rates in FSC-certified than in non-certified forests, especially for large mammals and species of high conservation priority. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Joeri A. Zwerts E. H. M. Sterck Pita A. Verweij Fiona Maisels Jaap van der Waarde Emma A. M. Geelen Georges Belmond Tchoumba Hermann Frankie Donfouet Zebaze Marijke van Kuijk Source Type: research
Distal colonocytes targeted by C. rodentium recruit T-cell help for barrier defence
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07288-1The murine enteropathogen Citrobacter rodentium targets a specific subset of absorptive intestinal epithelial cells in the mid–distal colon, which stimulate T cells to produce sustained IL-22 signals to mitigate further spread of the pathogen. (Source: Nature AOP)
Source: Nature AOP - April 10, 2024 Category: Research Authors: Carlene L. Zindl C. Garrett Wilson Awalpreet S. Chadha Lennard W. Duck Baiyi Cai Stacey N. Harbour Yoshiko Nagaoka-Kamata Robin D. Hatton Min Gao David A. Figge Casey T. Weaver Source Type: research
