Single-cell multiplex chromatin and RNA interactions in ageing human brain
Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07239-wWe introduce multinucleic acid interaction mapping in single cells (MUSIC), for concurrent profiling of multiplex chromatin interactions, gene expression and RNA–chromatin associations within individual nuclei, as a tool for exploring chromatin architecture and transcription. (Source: Nature AOP)
Source: Nature AOP - March 27, 2024 Category: Research Authors: Xingzhao Wen Zhifei Luo Wenxin Zhao Riccardo Calandrelli Tri C. Nguyen Xueyi Wan John Lalith Charles Richard Sheng Zhong Source Type: research

The complex circumstellar environment of supernova 2023ixf
Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07116-6Using ultraviolet data as well as a comprehensive set of further multiwavelength observations of the supernova 2023ixf, a reliable bolometric light curve is derived that indicates the heating nature of the early emission. (Source: Nature AOP)
Source: Nature AOP - March 27, 2024 Category: Research Authors: E. A. Zimmerman I. Irani P. Chen A. Gal-Yam S. Schulze D. A. Perley J. Sollerman A. V. Filippenko T. Shenar O. Yaron S. Shahaf R. J. Bruch E. O. Ofek A. De Cia T. G. Brink Y. Yang S. S. Vasylyev S. Ben Ami M. Aubert A. Badash J. S. Bloom P. J. Brown K. De Source Type: research

Revealing uncertainty in the status of biodiversity change
This study presents an approach to deal with spatial, temporal and phylogenetic non-independence in large-scale analyses of biodiversity change, improving trend estimation and inference across scales. (Source: Nature AOP)
Source: Nature AOP - March 27, 2024 Category: Research Authors: T. F. Johnson A. P. Beckerman D. Z. Childs T. J. Webb K. L. Evans C. A. Griffiths P. Capdevila C. F. Clements M. Besson R. D. Gregory G. H. Thomas E. Delmas R. P. Freckleton Source Type: research

Climate velocities and species tracking in global mountain regions
Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07264-9An analysis of the rate at which isotherms are shifting in mountain regions worldwide identifies 17 key regions with particularly high vertical isotherm shift velocities, and provides insight into how these shifts affect species ranges. (Source: Nature AOP)
Source: Nature AOP - March 27, 2024 Category: Research Authors: Wei-Ping Chan Jonathan Lenoir Guan-Shuo Mai Hung-Chi Kuo I-Ching Chen Sheng-Feng Shen Source Type: research

Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF
Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07250-1DCAF5 has a quality-control function for SWI/SNF complexes and promotes the degradation of incompletely assembled SWI/SNF complexes in the absence of SMARCB1. (Source: Nature AOP)
Source: Nature AOP - March 27, 2024 Category: Research Authors: Sandi Radko-Juettner Hong Yue Jacquelyn A. Myers Raymond D. Carter Alexis N. Robertson Priya Mittal Zhexin Zhu Baranda S. Hansen Katherine A. Donovan Moritz Hunkeler Wojciech Rosikiewicz Zhiping Wu Meghan G. McReynolds Shourya S. Roy Burman Anna M. Schmok Source Type: research