Congenital cytomegalovirus infection in a preterm infant with 22q11.2 deletion syndrome and immunological abnormalities
We report a case of a preterm infant with congenital cytomegalovirus infection complicated with 22q11.2 deletion syndrome and immunological abnormalities. Ultrasonography revealed pulmonary atresia, ventricular septal defect, major aortopulmonary collateral artery, and thymic hypoplasia. His serum chemistry tests on admission revealed immunoglobulin G, A, and M levels of 1,547 mg/dL, 70 mg/dL, and 274 mg/dL, respectively. A surface antigen analysis of the peripheral lymphocytes using flow cytometry revealed the following: relatively low CD4-positive T-cell levels (18.1%; 1,767/μL), very high CD8-positive T-cell levels (58...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Yoshihiko Shitara Etsushi Toyofuku Hideki Doi Takeo Mukai Kohei Kashima Satsuki Kakiuchi Motohiro Kato Naoto Takahashi Source Type: research

Seven-year follow-up of endovascular treatment of iatrogenic brachioradial artery injury complicating percutaneous coronary intervention: a case report
Nagoya J Med Sci. 2024 Feb;86(1):155-159. doi: 10.18999/nagjms.86.1.155.ABSTRACTThe radial artery has been used increasingly for percutaneous coronary intervention because of its safety and feasible access route. Nevertheless, transradial complications are possible because of the variation in radial artery anatomy. We experienced a case of the brachioradial artery injury secondary to catheterization, presenting as hypovolemic shock. A 76-year-old woman presented at our emergency department complaining of effort-induced angina. Coronary angiography via the right radial artery showed critical stenosis in the middle of the le...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Hyeon Wook Kim Sung Soo Kim Hyun Kuk Kim Young Jae Ki Keun Ho Park Dong Hyun Choi Source Type: research

<Editors' Choice> Thoracic endovascular aortic repair and spinal cord injury
Nagoya J Med Sci. 2024 Feb;86(1):16-23. doi: 10.18999/nagjms.86.1.16.ABSTRACTWe previously reported that spinal cord injury following thoracic endovascular aortic repair for a thoracic aortic aneurysm is a micro embolism caused by a vulnerable mural thrombus. Conversely, patients who underwent thoracic endovascular aortic repair for aortic dissection develop spinal cord injury less frequently due to fewer mural thrombi. Paying attention to preserving blood flow toward the spinal cord, namely collateral circulation and steal phenomenon, prevents spinal cord injury following thoracic endovascular aortic repair for aortic dis...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Hiroshi Banno Changi Lee Shuta Ikeda Yohei Kawai Masayuki Sugimoto Kiyoaki Niimi Source Type: research

<Editors' Choice> The relationship between preoperative foot alignment and postoperative outcomes in patients who underwent initial total knee arthroplasty
Nagoya J Med Sci. 2024 Feb;86(1):91-103. doi: 10.18999/nagjms.86.1.91.ABSTRACTWe compared the relationship between foot alignments and quality of life in patients who underwent initial total knee arthroplasty (TKA). Among the patients with knee osteoarthritis (KOA) who underwent TKA from May 2015 to May 2017 at our hospital, we focused on those in whom weight-bearing foot radiographs had been evaluated preoperatively. The hallux valgus angle and Meary angle were measured by preoperative radiography, and those with hallux valgus angles of 20 degrees or more were classified into the hallux valgus (HV) group, and those with M...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Aika Hishida Hideki Hiraiwa Izumi Kadono Hidetoshi Yamaguchi Takashi Okada Chiaki Terai Azusa Kayamoto Yoshihiro Nishida Source Type: research

The gonio scratch study: methodology of a multicenter clinical trial establishing a new minimally invasive glaucoma surgery
This study protocol was approved by the institutional review board of Hiroshima University. The trial results will be shared with the scientific community at international conferences and by publication in a peer-reviewed journal. Trial registration number is jRCTs062200003.PMID:38505714 | PMC:PMC10945225 | DOI:10.18999/nagjms.86.1.36 (Source: Nagoya Journal of Medical Science)
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Kana Tokumo Naoki Okada Tsukasa Mochizuki Hiromitsu Onoe Kaori Komatsu Hideaki Okumichi Kazuyuki Hirooka Hideki Mochizuki Mitsunobu Yokoyama Yoshiaki Kiuchi Source Type: research

The usefulness of shear wave elastography in evaluating erectile dysfunction severity before and after prostaglandin E1 test
Nagoya J Med Sci. 2024 Feb;86(1):104-109. doi: 10.18999/nagjms.86.1.104.ABSTRACTProstaglandin E1 intracavernous injection test is an established method for diagnosing erectile dysfunction. However, the evaluation is non-objective and often influenced by the evaluator's subjectivity. Herein, we measured and objectively evaluated shear wave elastography results of the corpus cavernosum before and after injection in 16 patients who underwent prostaglandin E1 testing. The response score of prostaglandin E1 tests were "1" in 2 cases, "2" in 2 cases, and "3" in 12 cases. The average transmission velocity before the injection and...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Fumitoshi Sakamoto Seiji Matsumoto Toshikazu Otani Yasuharu Takagi Tokunori Yamamoto Source Type: research

Long-term results of orbicularis oris muscle reconstruction in primary cleft lip repair using the "basket-weave method"
Nagoya J Med Sci. 2024 Feb;86(1):64-71. doi: 10.18999/nagjms.86.1.64.ABSTRACTThe basket-weave method is an orbicularis oris muscle reconstruction method used in primary unilateral cleft lip repair. We compared the long-term results of the basket-weave method with those of a conventional method. For primary unilateral cleft lip repair, we compared the long-term results of 7 cases in which the orbicularis oris muscle was reconstructed by use of the basket-weave method, and of 7 cases in which the reconstruction was performed by use of the conventional method. The average postoperative follow-up period was 12 years and 7 mont...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Masahiro Sasaki Shinji Togashi Yukiko Aihara Kaoru Sasaki Yoichiro Shibuya Junya Oshima Mitsuru Sekido Source Type: research

Nursing-care for family caregivers of terminally ill cancer patients to enhance preparedness for death
This study aims to structuralize nursing-care for preparedness and extract related factors while presenting the implications for improved quality of care. Data from a cross-sectional survey of general ward and palliative care unit nurses in designated cancer care hospitals (n=561) was analyzed with exploratory factor analysis and multiple regression analyses. The results of the analysis, the structure was classified into "Nurse-centered support" and "Support through inter-professional work." Both supports were practiced significantly more frequently in palliative care units than general wards. Related factors in general wa...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Akiko Unesoko Naoki Ozawa Ayumi Sugimura Kazuki Sato Shoko Ando Source Type: research

Protocol of a phase II study investigating the efficacy and safety of trifluridine/tipiracil plus ramucirumab as a third-line or later treatment for advanced gastric cancer
This study will recruit 32 patients according to eligibility criteria and administer FTD/TPI (35 mg/m2) and intravenous ramucirumab (8 mg/kg). The primary endpoint will be the time to treatment failure. The secondary endpoints will include the overall survival time, progression-free survival time, overall response rate, disease control rate, relative dose intensity, and incidence of adverse events. The results will add new insights for improving the late-line treatment of advanced gastric cancer.PMID:38505718 | PMC:PMC10945229 | DOI:10.18999/nagjms.86.1.43 (Source: Nagoya Journal of Medical Science)
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Koki Nakanishi Chie Tanaka Mitsuro Kanda Kazushi Miyata Nozomu Machida Mitsuru Sakai Daisuke Kobayashi Hitoshi Teramoto Akiharu Ishiyama Bin Sato Takashi Oshima Masaki Kajikawa Hidenobu Matsushita Kiyoshi Ishigure Katsuya Yamashita Shinichi Fujitake Satos Source Type: research

Rod fracture after multiple-rod technique for adult spinal deformity: a case report
Nagoya J Med Sci. 2024 Feb;86(1):135-141. doi: 10.18999/nagjms.86.1.135.ABSTRACTHere we report the case of a 71-year-old woman who complained of lower back and left leg pain due to rod fracture following instrumented fusion using the lateral lumbar interbody fusion and multi-rod technique to treat adult spinal deformity. Radiographic images revealed bilateral rod fractures at L4-5 and pseudoarthrosis at L2-5; lower lumbar lordosis was minimal, but upper lumbar hyperlordosis was noted. The patient underwent revision surgery, which included posterior spinal instrument replacement, L3-4 and L4-5 lateral lumbar interbody fusio...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Ippei Yamauchi Hiroaki Nakashima Masaaki Machino Sadayuki Ito Naoki Segi Ryoji Tauchi Tetsuya Ohara Noriaki Kawakami Shiro Imagama Source Type: research

Anxiety evaluated by the Hospital Anxiety and Depression Scale as a predictor of postoperative nausea and vomiting: a pilot study
In conclusion, the findings indicate that the HADS is worth investigating as a predictor of PONV.PMID:38505720 | PMC:PMC10945218 | DOI:10.18999/nagjms.86.1.72 (Source: Nagoya Journal of Medical Science)
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Tatsuro Yokoyama Takahiro Tamura Kazuki Nishida Ryohei Ito Kimitoshi Nishiwaki Source Type: research

Factors associated with perineal pain on the first postnatal day after vaginal delivery: a cross-sectional study of primiparous women
Nagoya J Med Sci. 2024 Feb;86(1):52-63. doi: 10.18999/nagjms.86.1.52.ABSTRACTMany women report postpartum perineal pain due to perineal trauma after vaginal delivery. Perineal pain after giving birth declines over time; however, perineal trauma and pain negatively impact on the women's quality of life and their ability to care for their children. The degree of perineal trauma and instrument delivery with episiotomy are associated with perineal pain. Nevertheless, no studies have examined factors related to postpartum perineal pain, including weight changes during pregnancy as well as the course of delivery so far. We aimed...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Akiko Yamada Yuki Takahashi Masami Hirose Yurika Usami Saho Maruya Koji Tamakoshi Source Type: research

Development and validation of nursing students' moral sensitivity questionnaire in Taiwan
The objective of this study was to develop a reliable tool for assessing moral sensitivity among nursing students. The questionnaire was developed following a rigorous approach, consisting of three stages process, combining the Schwartz-Barcott and Kim hybrid model of concept development with the methodology suggested by Devellis and Waltz. A total of 297 nursing students (287 females, 10 males; mean age: 18.7 years) participated in the study, with five invalid questionnaires excluded from the analysis. The questionnaire's reliability was established through internal consistency and test-retest reliability analyses. Furthe...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Hsiao-Lu Lee Chiu-Mieh Huang Source Type: research

Relationship between exercise habits and physical function in children aged 9-12 years
In conclusion, exercise regardless of exercise level for at least 30 min per day, 2 days per week, for at least 1 year is important for skeletal muscle mass and instantaneous lower limb muscular strength development in school-aged children.PMID:38505723 | PMC:PMC10945223 | DOI:10.18999/nagjms.86.1.24 (Source: Nagoya Journal of Medical Science)
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Daiki Takahashi Tadashi Ito Yuji Ito Kentaro Natsume Koji Noritake Nobuhiko Ochi Hideshi Sugiura Source Type: research

Safety of antiplatelet therapy during the perioperative period of revascularization surgery for moyamoya disease patients with ischemic onset
This study aimed to determine the impact of antiplatelet agents on adult moyamoya disease patients with ischemic onset during the perioperative period. From January 2016 to December 2020, 183 consecutive combined (direct and indirect) revascularization surgeries for moyamoya disease patients were performed. Among these surgeries, 96 consecutive combined revascularization surgeries for adult moyamoya disease patients with ischemic onset were analyzed and perioperative ischemic and hemorrhagic complications were reviewed. Antiplatelet agents were continued during the perioperative period including on the day of surgery and t...
Source: Nagoya Journal of Medical Science - March 20, 2024 Category: International Medicine & Public Health Authors: Akihiro Nakamura Syuntaro Takasu Yukio Seki Ryuta Saito Source Type: research