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Effective attenuation of glyphosate ‐induced oxidative stress and granulosa cell apoptosis by vitamins C and E in caprines
The present study aims at assessing the GLP (0.1, 2.0, and 4.0  mg/ml) induced granulosa cells toxicity and evaluating the mitigating effects of vitamins C& E (0.5  mM and 1.0 mM) in healthy caprine antral follicles, cultured in vitro in dose and time (24, 48, and 72 hr) dependent manner and subjected to various cytotoxic and geno‐toxic analysis namely classic histology, EB/AO differential staining, oxidative stress parameters, and antioxidant enzymati c activity. Pesticides are known to cause a wide range of reproductive problems that possess degenerative effects on mammalian fertility. Glyphosate (GLP), a broad...
Source: Molecular Reproduction and Development - November 26, 2018 Category: Reproduction Medicine Authors: Jitender Kumar Bhardwaj, Meenu Mittal, Priyanka Saraf Tags: RESEARCH ARTICLE Source Type: research

Transcriptome analysis provides insights into differentially expressed genes and long noncoding RNAs involved in sex ‐related differences in Amur sturgeon (Acipenser schrenckii)
AbstractIn the present study, the next ‐generation sequencing technology was used to develop a transcriptome database of gonad and liver from 3‐year‐old male and female Amur sturgeons (Acipenser schrenckii). A total of 139,406 unigenes were generated after the Illumina Hiseq. 2500 sequence and assembled by Trinity. The differential expression analysis between male and female obtained 5,199 differentially expressed genes (DEGs) in gonad and 457 DEGs in liver. Gene Ontology enrich analysis showed that the specific DEGs of gonad play a dominant role in reproductive processes. Although the specific DEGs of liver indicate...
Source: Molecular Reproduction and Development - November 26, 2018 Category: Reproduction Medicine Authors: Xin Zhang, Jialong Shi, Yulong Sun, Youfang Zhu, Ziping Zhang, Yilei Wang Tags: RESEARCH ARTICLE Source Type: research

Changes in the uterine metabolome of the cow during the first 7 days after estrus
In conclusion, the metabolome of the bovine uterus changes during early stages of the estrous cycle and is likely to participa te in the regulation of preimplantation embryonic development. Data reported here will serve as the basis for future studies aiming to evaluate maternal regulation of preimplantation embryonic development and optimal conditions for the culture of embryos. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 25, 2018 Category: Reproduction Medicine Authors: Paula Tr íbulo, Leandro Balzano‐Nogueira, Ana Conesa, Luiz G. Siqueira, Peter J. Hansen Tags: RESEARCH ARTICLE Source Type: research

miR ‐34 regulates reproduction by inhibiting the expression of MIH, CHH, EcR, and FAMeT genes in mud crab Scylla paramamosain
In this study, we used bioinformatic tools to identify the target genes of miR‐34 in eyestalk. Six reproduction‐related genes wi th an intact 3′‐untranslated region (UTR), including molt‐inhibiting hormone (MIH), crustacean hyperglycemic hormone (CHH), vitellogenesis‐inhibiting hormone, red pigment concentrating hormone, ecdysone receptor (EcR), and farnesoic acid methyltransferase (FAMeT) were identified. When the 3′ ‐UTR plasmid vectors of the six genes were cotransfected with miR‐34 mimics into 293FT cells, respectively, the luciferase activities of four genes (MIH, CHH, EcR, and FAMeT) were significan...
Source: Molecular Reproduction and Development - November 25, 2018 Category: Reproduction Medicine Authors: Mingcan Zhou, Xiwei Jia, Haifu Wan, Shuhong Wang, Xin Zhang, Ziping Zhang, Yilei Wang Tags: RESEARCH ARTICLE Source Type: research

Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro
This study demonstrates that hesperetin protects oocytes against oxidative stress during aging in vitro. The citrus flavonoid hesperetin has a variety of pharmacological actions, including antioxidant, antiinflammatory, and anticancer activities. This study investigated whether hesperetin prevents aging of oocytes in vitro in which it determined the maturation of nuclear and cytoplasm and the developmental capacity of embryo by modulating the reactive oxygen species (ROS) level. Porcine oocytes were matured in vitro for 44  hr (control) and for an additional 24 hr in the presence of 0, 1, 10, 100, and 250 μM hespere...
Source: Molecular Reproduction and Development - November 23, 2018 Category: Reproduction Medicine Authors: Won ‐Jae Kim, Seung‐Eun Lee, Yun‐Gwi Park, Sang‐Gi Jeong, Eun‐Young Kim, Se‐Pill Park Tags: RESEARCH ARTICLE Source Type: research

The following five articles for this Special Issue were previously published and can be found in their respective issues or online
Molecular Reproduction and Development, Volume 85, Issue 11, November 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 20, 2018 Category: Reproduction Medicine Tags: SPECIAL ISSUE ARTICLE Source Type: research

Cover Image, Volume 85, Issue 11, November 2018
(Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 20, 2018 Category: Reproduction Medicine Tags: COVER Source Type: research

Table of Contents, Volume 85, Issue 11, November 2018
Molecular Reproduction and Development, Volume 85, Issue 11, Page 807-808, November 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 20, 2018 Category: Reproduction Medicine Tags: ISSUE INFORMATION Source Type: research

Coordinated expression of the VEGF system components in granulosa cells to develop a pro ‐angiogenic autocrine milieu during ovarian follicle development
In conclusion, the higher mRNA expression forVEGF120a andVEGF164a, the low expression ofsVEGFR2 and absent expression of mRNA forVEGF164b provide evidence of a pro ‐angiogenic autocrine milieu to support granulosa cells during follicle development.This article is protected by copyright. All rights reserved. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 15, 2018 Category: Reproduction Medicine Authors: Diana Zamora ‐Gutiérrez, Adrian Guzmán, Cyndi G Hernández‐Coronado, Héctor Castillo‐Juárez, Francisco Fierro, Carlos G Gutiérrez, Rafael Bojalil, Ana Ma. Rosales‐Torres Tags: RESEARCH ARTICLE Source Type: research

Expression of β‐NGF and high‐affinity NGF receptor (TrKA) in llama (Lama glama) male reproductive tract and spermatozoa
This study extends the knowledge about the participation of β‐NGF/TrkA in llama reproduction, providi ng evidence that may have roles in the regulation of sperm physiology. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 14, 2018 Category: Reproduction Medicine Authors: Luciana M. Sari, Renato Zampini, Martin E. Arga ñaraz, María I. Carretero, Fernanda G. Fumuso, Daniela E. Barraza, Marcelo Ratto, Silvana A. Apichela Tags: RESEARCH ARTICLE Source Type: research

Lipidomic profile as a non ‐invasive tool to predict endometrial receptivity
This article is protected by copyright. All rights reserved. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 12, 2018 Category: Reproduction Medicine Authors: Daniela Paes Almeida Ferreira Braga, Edson Borges, Adriana Teixeira Godoy, Daniela Antunes Montani, Amanda Souza Setti, Bianca Ferrarini Zanetti, Rita C ássia Sávio Figueira, Marcos Nogueira Eberlin, Edson Guimarães Lo Turco Tags: RESEARCH ARTICLE Source Type: research

Uterine RGS2 expression is regulated by exogenous estrogen and progesterone in ovariectomized mice, and down ‐regulation of RGS2 expression in artificial decidualized ESCs inhibits trophoblast spreading in vitro
This article is protected by copyright. All rights reserved. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 9, 2018 Category: Reproduction Medicine Authors: Manxi Jiang, Liangshan Hu, Baoping Wang, Danxia Chen, Yahong Li, Zhen Zhang, Yan Zhu Tags: RESEARCH ARTICLE Source Type: research

Expression Profiles of Interferon ‐Stimulated Gene 15 and Prostaglandin Synthases in the Ovine Lymph Nodes during Early Pregnancy
In conclusion, the ISG15, COX‐1, COX‐ 2, PTGES and AKR1B1 were up‐regulated in the maternal lymph nodes, which may be beneficial for the development of conceptus, maternal systemic immunoregulation and anti‐luteolysis during early pregnancy in sheep.This article is protected by copyright. All rights reserved. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 8, 2018 Category: Reproduction Medicine Authors: Ling Yang, Qingkai Wang, Yong Liu, Leying Zhang, Wan Lv, Baoliang Liu Tags: RESEARCH ARTICLE Source Type: research

The Eggstraordinary Story of How Life Begins
This article is protected by copyright. All rights reserved. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 8, 2018 Category: Reproduction Medicine Authors: John Parrington, Christophe Arnoult, Rafael A. Fissore Tags: REVIEW ARTICLE Source Type: research

Effective Attenuation of Glyphosate Induced Oxidative Stress and Granulosa Cell Apoptosis by Vitamin C and E in Caprines
This article is protected by copyright. All rights reserved. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 8, 2018 Category: Reproduction Medicine Authors: Jitender Kumar Bhardwaj, Meenu Mittal, Priyanka Saraf Tags: RESEARCH ARTICLE Source Type: research