Correction: Challenge accepted: Uncovering the role of rare genetic variants in Alzheimer ’s disease
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - November 1, 2022 Category: Neurology Authors: Marzieh Khani, Elizabeth Gibbons, Jose Bras and Rita Guerreiro Tags: Correction Source Type: research
Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (part 2): the 2021 pre-symposium of the 15th international conference on Alzheimer ’s and Parkinson’s diseases
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - November 1, 2022 Category: Neurology Authors: Sharyn L. Rossi, Preeti Subramanian, Guojun Bu, Adriana Di Polo, Todd E. Golde and Diane E. Bovenkamp Tags: Meeting report Source Type: research
Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (Part 1): the 2021 pre-symposium of the 15th international conference on Alzheimer ’s and Parkinson’s diseases
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - October 31, 2022 Category: Neurology Authors: Sharyn L. Rossi, Preeti Subramanian, Guojun Bu, Adriana Di Polo, Todd E. Golde and Diane E. Bovenkamp Tags: Meeting report Source Type: research
The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer ’s disease?
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - October 21, 2022 Category: Neurology Authors: Yanzhuang Wang and Sam Gandy Tags: Perspective Source Type: research
Tau interactome and RNA binding proteins in neurodegenerative diseases
Pathological tau aggregation is a primary neuropathological feature of many neurodegenerative diseases. Intriguingly, despite the common presence of tau aggregates in these diseases the affected brain regions,... (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - October 17, 2022 Category: Neurology Authors: Tomas Kavanagh, Aditi Halder and Eleanor Drummond Tags: Review Source Type: research
Liver-ing in your head rent free: peripheral ApoE4 drives CNS pathology
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - October 4, 2022 Category: Neurology Authors: Lesley R. Golden and Lance A. Johnson Tags: Research highlight Source Type: research
Author response to “post-infection cognitive impairments in a cohort of elderly patients with COVID-19”
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 26, 2022 Category: Neurology Authors: Yu-Hui Liu, Ye-Ran Wang, Qing-Hua Wang, Juan Liu and Yan-Jiang Wang Tags: Letter to the Editor Source Type: research
To the editor: Response to post-infection cognitive impairments in a cohort of elderly patients with COVID-19, by Wang, Y.J. et al. (2021)
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 25, 2022 Category: Neurology Authors: Rahmouni Nesrine, Rosa-Neto Pedro and Brunet Alain Tags: Letter to the Editor Source Type: research
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer ’s disease pathology and brain diseases
ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of the most influential risk factors for ... (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 24, 2022 Category: Neurology Authors: Rosal ía Fernández-Calle, Sabine C. Konings, Javier Frontiñán-Rubio, Juan García-Revilla, Lluís Camprubí-Ferrer, Martina Svensson, Isak Martinson, Antonio Boza-Serrano, José Luís Venero, Henrietta M. Nielsen, Gunnar K. Gouras and Tomas Deierborg Tags: Review Source Type: research
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity
Alzheimer ’s Disease (AD) affects millions globally, but therapy development is lagging. New experimental systems that monitor neuronal functions in conditions approximating the AD brain may be beneficial for i... (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 21, 2022 Category: Neurology Authors: Yi-Chen Hsieh, Joseph Negri, Amy He, Richard V. Pearse II, Lei Liu, Duc M. Duong, Lori B. Chibnik, David A. Bennett, Nicholas T. Seyfried and Tracy L. Young-Pearse Tags: Research article Source Type: research
Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits in a mouse model of DLB/PD
Although ɑ-synuclein (ɑ-syn) spreading in age-related neurodegenerative diseases such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) has been extensively investigated, the role of aging in the... (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 5, 2022 Category: Neurology Authors: Michiyo Iba, Ross A. McDevitt, Changyoun Kim, Roshni Roy, Dimitra Sarantopoulou, Ella Tommer, Byron Siegars, Michelle Sallin, Somin Kwon, Jyoti Misra Sen, Ranjan Sen and Eliezer Masliah Tags: Research article Source Type: research
LRP1 is a neuronal receptor for α-synuclein uptake and spread
The aggregation and spread of α-synuclein (α-Syn) protein and related neuronal toxicity are the key pathological features of Parkinson’s disease (PD) and Lewy body dementia (LBD). Studies have shown that patho... (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 2, 2022 Category: Neurology Authors: Kai Chen, Yuka A. Martens, Axel Meneses, Daniel H. Ryu, Wenyan Lu, Ana Caroline Raulin, Fuyao Li, Jing Zhao, Yixing Chen, Yunjung Jin, Cynthia Linares, Marshall Goodwin, Yonghe Li, Chia-Chen Liu, Takahisa Kanekiyo, David M. Holtzman & hellip; Tags: Research article Source Type: research
Trem2 deletion enhances tau dispersion and pathology through microglia exosomes
Alzheimer ’s disease (AD) is a neurodegenerative disorder that manifests sequential Aβ and tau brain pathology with age-dependent onset. Variants in the microglial immune receptor TREM2 are associated with enha... (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 2, 2022 Category: Neurology Authors: Bing Zhu, Yan Liu, Spring Hwang, Kailey Archuleta, Huijie Huang, Alex Campos, Rabi Murad, Juan Pi ña-Crespo, Huaxi Xu and Timothy Y. Huang Tags: Research article Source Type: research
CD8+ T cells in neurodegeneration: friend or foe?
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - September 2, 2022 Category: Neurology Authors: Dan Hu, Weiming Xia and Howard L. Weiner Tags: Perspective Source Type: research
Correction: Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
(Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - August 30, 2022 Category: Neurology Authors: A. Harrison Brody, Sarah Helena Nies, Fulin Guan, Levi M. Smith, Bandhan Mukherjee, Santiago A. Salazar, Suho Lee, Tu Kiet T. Lam and Stephen M. Strittmatter Tags: Correction Source Type: research
