Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Publication date: Available online 13 September 2020Source: Molecular MetabolismAuthor(s): Marie Winther-Sørensen, Katrine D. Galsgaard, Alberto Santos, Samuel A.J. Trammell, Karolina Sulek, Rune E. Kuhre, Jens Pedersen, Daniel B. Andersen, Anna S. Hassing, Morten Dall, Jonas T. Treebak, Matthew P. Gillum, Signe S. Torekov, Johanne A. Windeløv, Jenna E. Hunt, Sasha A.S. Kjeldsen, Sara L. Jepsen, Catherine G. Vasilopoulou, Filip K. Knop, Cathrine Ørskov (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 14, 2020 Category: Endocrinology Source Type: research
Maternal obesity causes fetal hypothalamic insulin resistance and disrupts development of hypothalamic feeding pathways
Publication date: Available online 9 September 2020Source: Molecular MetabolismAuthor(s): L. Dearden, S. Buller, I.C. Furigo, D.S. Fernandez-Twinn, S.E. Ozanne (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 10, 2020 Category: Endocrinology Source Type: research
Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells
Publication date: Available online 9 September 2020Source: Molecular MetabolismAuthor(s): Devika P. Bagchi, Akira Nishii, Ziru Li, Jennifer B. DelProposto, Callie A. Corsa, Hiroyuki Mori, Julie Hardij, Brian S. Learman, Carey N. Lumeng, Ormond A. MacDougald (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 10, 2020 Category: Endocrinology Source Type: research
Corrigendum to “Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort” [Molecular Metabolism 34 (2020) 85–96]
Publication date: Available online 8 September 2020Source: Molecular MetabolismAuthor(s): Agné Kulyté, Veroniqa Lundbäck, Cecilia M. Lindgren, Jian'an Luan, Luca A. Lotta, Claudia Langenberg, Peter Arner, Rona J. Strawbridge, Ingrid Dahlman (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 9, 2020 Category: Endocrinology Source Type: research
Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity and are not protected from a hypercaloric diet
Publication date: Available online 9 September 2020Source: Molecular MetabolismAuthor(s): Daniela Rojo, Clara McCarthy, Jesica Raingo, Marcelo Rubinstein (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 9, 2020 Category: Endocrinology Source Type: research
Purification of pancreatic endocrine subsets reveals increased iron metabolism in beta cells
Publication date: Available online 5 August 2020Source: Molecular MetabolismAuthor(s): C. Berthault, W. Staels, R. Scharfmann (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 8, 2020 Category: Endocrinology Source Type: research
Infusion of donor feces affects the gut-brain axis in humans with metabolic syndrome
Publication date: Available online 8 September 2020Source: Molecular MetabolismAuthor(s): Annick V. Hartstra, Valentina Schüppel, Sultan Imangaliyev, Anouk Schrantee, Andrei Prodan, Didier Collard, Evgeni Levin, Geesje Dallinga-Thie, Mariette T. Ackermans, Maaike Winkelmeijer, Stefan R. Havik, Amira Metwaly, Ilias Lagkouvardos, Anika Nier, Ina Bergheim, Mathias Heikenwalder, Andreas Dunkel, Aart J. Nederveen, Gerhard Liebisch, Giulia Mancano (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 8, 2020 Category: Endocrinology Source Type: research
Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP-Binding cassette subfamily G member 1
Publication date: Available online 13 August 2020Source: Molecular MetabolismAuthor(s): Serena Barilla, Ning Liang, Enrichetta Mileti, Raphaëlle Ballaire, Marie Lhomme, Maharajah Ponnaiah, Sophie Lemoine, Antoine Soprani, Jean-Francois Gautier, Ez-Zoubir Amri, Wilfried Le Goff, Nicolas Venteclef, Eckardt Treuter (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 7, 2020 Category: Endocrinology Source Type: research
SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans
Publication date: Available online 5 September 2020Source: Molecular MetabolismAuthor(s): Heeyoung Chae, Robert Augustin, Eva Gatineau, Eric Mayoux, Mohammed Bensellam, Nancy Antoine, Firas Khattab, Bao-Khanh Lai, Davide Brusa, Birgit Stierstorfer, Holger Klein, Bilal Singh, Lucie Ruiz, Michael Pieper, Michael Mark, Pedro L. Herrera, Fiona M. Gribble, Frank Reimann, Anne Wojtusciszyn, Christophe Broca (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 6, 2020 Category: Endocrinology Source Type: research
Corrigendum to “Molecular regulation of urea cycle function by the liver glucocorticoid receptor” [Mol Metab 4 (10) (2015 Oct) 732–740]
Publication date: Available online 5 September 2020Source: Molecular MetabolismAuthor(s): Jürgen G. Okun, Sean Conway, Kathrin V. Schmidt, Jonas Schumacher, Xiaoyue Wang, Roldan de Guia, Annika Zota, Johanna Klement, Oksana Seibert, Achim Peters, Adriano Maida, Stephan Herzig, Adam J. Rose (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 6, 2020 Category: Endocrinology Source Type: research
Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons
Publication date: Available online 6 September 2020Source: Molecular MetabolismAuthor(s): Anthony H. Tsang, Danae Nuzacci, Tamana Darwish, Havish Samudrala, Clémence Blouet (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 6, 2020 Category: Endocrinology Source Type: research
Corrigendum to “Interactions between metabolism and chromatin in plant models” [Mol Metab 38 (Aug 2020) 100951]
Publication date: Available online 4 September 2020Source: Molecular MetabolismAuthor(s): Christian Lindermayr, Eva Esther Rudolf, Jörg Durner, Martin Groth (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 4, 2020 Category: Endocrinology Source Type: research
Gut microbiota impairs insulin clearance in obese mice
Publication date: Available online 26 August 2020Source: Molecular MetabolismAuthor(s): Kevin P. Foley, Soumaya Zlitni, Brittany M. Duggan, Nicole G. Barra, Fernando F. Anhê, Joseph F. Cavallari, Brandyn D. Henriksbo, Cassandra Y. Chen, Michael Huang, Trevor C. Lau, Roxanne Plante, Michael Schwab, André Marette, Jonathan D. Schertzer (Source: Molecular Metabolism)
Source: Molecular Metabolism - August 26, 2020 Category: Endocrinology Source Type: research
Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D
Publication date: Available online 30 July 2020Source: Molecular MetabolismAuthor(s): Dana Avrahami, Yue J. Wang, Jonathan Schug, Eseye Feleke, Long Gao, Chengyang Liu, HPAP Consortium, Ali Naji, Benjamin Glaser, Klaus H. Kaestner (Source: Molecular Metabolism)
Source: Molecular Metabolism - August 21, 2020 Category: Endocrinology Source Type: research
Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy
Publication date: Available online 7 August 2020Source: Molecular MetabolismAuthor(s): Joseph J. Bass, Asif Nakhuda, Colleen S. Deane, Matthew S. Brook, Daniel J. Wilkinson, Bethan E. Phillips, Andrew Philp, Janelle Tarum, Fawzi Kadi, Ditte Andersen, Amadeo Muñoz Garcia, Ken Smith, Iain J. Gallagher, Nathaniel J. Szewczyk, Mark E. Cleasby, Philip J. Atherton (Source: Molecular Metabolism)
Source: Molecular Metabolism - August 21, 2020 Category: Endocrinology Source Type: research
