Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo
Publication date: Available online 19 September 2020Source: Molecular MetabolismAuthor(s): Melanie J. Mittenbühler, Katarzyna Saedler, Hendrik Nolte, Lara Kern, Jun Zhou, Shu-Bing Qian, Lydia Meder, Roland T. Ullrich, Jens C. Brüning, F. Thomas Wunderlich (Source: Molecular Metabolism)
Source: Molecular Metabolism - October 1, 2020 Category: Endocrinology Source Type: research

Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling
Publication date: Available online 22 September 2020Source: Molecular MetabolismAuthor(s): Feixiang Yuan, Hanrui Yin, Yalan Deng, Fuxin Jiao, Haizhou Jiang, Yuguo Niu, Shanghai Chen, Hao Ying, Qiwei Zhai, Yan Chen, Feifan Guo (Source: Molecular Metabolism)
Source: Molecular Metabolism - October 1, 2020 Category: Endocrinology Source Type: research

Anticancer strategy targeting the energy metabolism of tumor cells surviving a low-nutrient acidic microenvironment (R1)
Publication date: Available online 30 September 2020Source: Molecular MetabolismAuthor(s): Yuki Maeda, Ryota Kikuchi, Junichiro Kawagoe, Takao Tsuji, Nobuyuki Koyama, Kazuhiro Yamaguchi, Hiroyuki Nakamura, Kazutetsu Aoshiba (Source: Molecular Metabolism)
Source: Molecular Metabolism - October 1, 2020 Category: Endocrinology Source Type: research

Dysregulated lipid metabolism links NAFLD to cardiovascular disease
Publication date: Available online 1 October 2020Source: Molecular MetabolismAuthor(s): Audrey Deprince, Joel T. Haas, Bart Staels (Source: Molecular Metabolism)
Source: Molecular Metabolism - October 1, 2020 Category: Endocrinology Source Type: research

Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome
Publication date: Available online 8 September 2020Source: Molecular MetabolismAuthor(s): Annick V. Hartstra, Valentina Schüppel, Sultan Imangaliyev, Anouk Schrantee, Andrei Prodan, Didier Collard, Evgeni Levin, Geesje Dallinga-Thie, Mariette T. Ackermans, Maaike Winkelmeijer, Stefan R. Havik, Amira Metwaly, Ilias Lagkouvardos, Anika Nier, Ina Bergheim, Mathias Heikenwalder, Andreas Dunkel, Aart J. Nederveen, Gerhard Liebisch, Giulia Mancano (Source: Molecular Metabolism)
Source: Molecular Metabolism - October 1, 2020 Category: Endocrinology Source Type: research

Prolonged fasting drives a program of metabolic inflammation in human adipose tissue
Publication date: Available online 28 September 2020Source: Molecular MetabolismAuthor(s): Pouneh K. Fazeli, Yang Zhang, John O'Keefe, Tristan Pesaresi, Mingyue Lun, Brian Lawney, Matthew L. Steinhauser (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 29, 2020 Category: Endocrinology Source Type: research

Adipocytes Fail to Maintain Cellular Identity During Obesity Due to Reduced PPARγ Activity and Elevated TGFβ-SMAD Signaling
Publication date: Available online 28 September 2020Source: Molecular MetabolismAuthor(s): Hyun Cheol Roh, Manju Kumari, Solaema Taleb, Danielle Tenen, Christopher Jacobs, Anna Lyubetskaya, Linus T.-Y. Tsai, Evan D. Rosen (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 29, 2020 Category: Endocrinology Source Type: research

Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis
Publication date: Available online 28 September 2020Source: Molecular MetabolismAuthor(s): Anna Fenzl, Oana Cristina Kulterer, Katrin Spirk, Goran Mitulović, Rodrig Marculescu, Martin Bilban, Sabina Baumgartner-Parzer, Alexandra Kautzky-Willer, Lukas Kenner, Jorge Plutzky, Loredana Quadro, Florian W. Kiefer (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 29, 2020 Category: Endocrinology Source Type: research

P2Y2R contributes to the development of diabetic nephropathy by inhibiting autophagy response
Publication date: Available online 25 September 2020Source: Molecular MetabolismAuthor(s): Theodomir Dusabimana, So Ra Kim, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 26, 2020 Category: Endocrinology Source Type: research

Glucagon-like Peptide-1 Receptor co-agonists for the treatment of metabolic disease
Publication date: Available online 25 September 2020Source: Molecular MetabolismAuthor(s): Laurie L. Baggio, Daniel J. Drucker (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 26, 2020 Category: Endocrinology Source Type: research

Reversal of Diet-induced Hepatic Steatosis by Peripheral CB1 Receptor Blockade in Mice is p53/miRNA-22/SIRT1/PPARα Dependent
Publication date: Available online 26 September 2020Source: Molecular MetabolismAuthor(s): Shahar Azar, Shiran Udi, Adi Drori, Rivka Hadar, Alina Nemerovski, Kiran V. Vemuri, Maya Miller, Dana Sherill-Rofe, Yhara Arad, Devorah Gur-Wahnon, Xiaoling Li, Alexandros Makriyannis, Danny Ben-Zvi, Yuval Tabach, Iddo Z. Ben-Dov, Joseph Tam (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 26, 2020 Category: Endocrinology Source Type: research

Over-expression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling
Publication date: Available online 22 September 2020Source: Molecular MetabolismAuthor(s): Feixiang Yuan, Hanrui Yin, Yalan Deng, Fuxin Jiao, Haizhou Jiang, Yuguo Niu, Shanghai Chen, Hao Ying, Qiwei Zhai, Yan Chen, Feifan Guo (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 23, 2020 Category: Endocrinology Source Type: research

Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice
Publication date: Available online 18 September 2020Source: Molecular MetabolismAuthor(s): Sarah Saget, Rong Cong, Lyvianne Decourtye, Marie-Laure Endale, Laetitia Martinerie, Clémence Girardet, Claire Perret, Maud Clemessy, Patricia Leneuve, Laetitia Dinard, Badreddine Mohand Oumoussa, Dominique Farabos, Antonin Lamazière, Marc Lombès, Marthe Moldes, Bruno Fève, David Tregouet, Yves Le Bouc, Laurent Kappeler (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 20, 2020 Category: Endocrinology Source Type: research

Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo
Publication date: Available online 19 September 2020Source: Molecular MetabolismAuthor(s): Melanie J. Mittenbühler, Katarzyna Saedler, Hendrik Nolte, Lara Kern, Jun Zhou, Shu-Bing Qian, Lydia Meder, Roland T. Ullrich, Jens C. Brüning, F. Thomas Wunderlich (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 20, 2020 Category: Endocrinology Source Type: research

Regulation of lymphatic function and injury by nitrosative stress in obese mice
Publication date: Available online 14 September 2020Source: Molecular MetabolismAuthor(s): Sonia Rehal, Raghu P. Kataru, Geoffrey E. Hespe, Jung Eun Baik, Hyeung Ju Park, Catherine Ly, JinYeon Shin, Babak J. Mehrara (Source: Molecular Metabolism)
Source: Molecular Metabolism - September 15, 2020 Category: Endocrinology Source Type: research