[Corrigendum] Upregulation of centromere protein M promotes tumorigenesis:  A potential predictive target for cancer in humans
Mol Med Rep. 2024 Apr;29(4):62. doi: 10.3892/mmr.2024.13186. Epub 2024 Feb 23.ABSTRACTSubsequently to the publication of this paper, the authors' have realized that Fig. 2A on p. 3927 was published featuring an error; specifically, there was an unintentional duplication of one of the representative images chosen for the figure (the same image was selected to represent the 'BRCA/Normal' and 'Tumor/LUSC' experiments). Additionally, the sample numbers in Fig. 2A were also incorrect. The correct sample numbers are as follows: 3 samples of breast tissue, 12 samples of breast cancer tissue, 3 samples of normal cervical tissue, 9...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ying Liu Wenfeng Yu Peng Ren Ting Zhang Source Type: research

NLRP3 deficiency protects against acetaminophen ‑induced liver injury by inhibiting hepatocyte pyroptosis
Mol Med Rep. 2024 Apr;29(4):61. doi: 10.3892/mmr.2024.13185. Epub 2024 Feb 23.ABSTRACTAcetaminophen (APAP) overdose is the primary cause of drug‑induced acute liver failure in numerous Western countries. NLR family pyrin domain containing 3 (NLRP3) inflammasome activation serves a pivotal role in the pathogenesis of various forms of acute liver injury. However, the cellular source for NLRP3 induction and its involvement during APAP‑induced hepatotoxicity have not been thoroughly investigated. In the present study, hematoxylin and eosin staining was performed to assess histopathological changes of liver tissue. Immunohi...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Xinying Yuan Peng Chen Xiaoyu Luan Chaoqun Yu Longyu Miao Yaru Zuo Anxu Liu Tianyi Sun Guohu Di Source Type: research

Effect of prothymosin α on neuroplasticity following cerebral ischemia‑reperfusion injury
Mol Med Rep. 2024 Apr;29(4):59. doi: 10.3892/mmr.2024.13183. Epub 2024 Feb 23.ABSTRACTProthymosin α (ProT), a highly acidic nuclear protein with multiple cellular functions, has shown potential neuroprotective properties attributed to its anti‑necrotic and anti‑apoptotic activities. The present study aimed to investigate the beneficial effect of ProT on neuroplasticity after ischemia‑reperfusion injury and elucidate its underlying mechanism of action. Primary cortical neurons were either treated with ProT or overexpressing ProT by gene transfection and exposed to oxygen‑glucose deprivation for 2 h in vitro. Immuno...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ai-Chiang Lee Shih-Huang Tai Yi-Yun Chen Sheng-Yang Huang Chao-Liang Wu E-Jian Lee Source Type: research

Research advances of MAL family members in tumorigenesis and tumor progression (Review)
Mol Med Rep. 2024 Apr;29(4):57. doi: 10.3892/mmr.2024.13181. Epub 2024 Feb 16.ABSTRACTThe myelin and lymphocyte protein (MAL) family is a novel gene family first identified and characterized in 2002. This family is comprised of seven members, including MAL, MAL2, plasmolipin, MALL, myeloid differentiation‑associated marker (MYADM), MYADML2 and CMTM8, which are located on different chromosomes. In addition to exhibiting extensive activity during transcytosis, the MAL family plays a vital role in the neurological, digestive, respiratory, genitourinary and other physiological systems. Furthermore, the intimate association b...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Mengyao Li Yan Du Xianzhuo Zhang Wence Zhou Source Type: research

[Corrigendum] microRNA ‑181a‑5p functions as an oncogene in renal cell carcinoma
Mol Med Rep. 2024 Apr;29(4):58. doi: 10.3892/mmr.2024.13182. Epub 2024 Feb 16.ABSTRACTFollowing the publication of the above article and a corrigendum in 2018 that corrected details of the correspondence information for authors, errors made in Fig. 5 and the funding details (doi: 10.3892/mmr.2018.9117), an interested reader drew to the authors' attention that, in Fig. 6 on p. 8515 showing the results of cell migration and invasion assay experiments, a pair of data panels were overlapping, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the sam...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Yulin Lai Liwen Zhao Jia Hu Jing Quan Peijie Chen Jinling Xu Xin Guan Yongqing Lai Liangchao Ni Source Type: research

Research advances of MAL family members in tumorigenesis and tumor progression (Review)
Mol Med Rep. 2024 Apr;29(4):57. doi: 10.3892/mmr.2024.13181. Epub 2024 Feb 16.ABSTRACTThe myelin and lymphocyte protein (MAL) family is a novel gene family first identified and characterized in 2002. This family is comprised of seven members, including MAL, MAL2, plasmolipin, MALL, myeloid differentiation‑associated marker (MYADM), MYADML2 and CMTM8, which are located on different chromosomes. In addition to exhibiting extensive activity during transcytosis, the MAL family plays a vital role in the neurological, digestive, respiratory, genitourinary and other physiological systems. Furthermore, the intimate association b...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Mengyao Li Yan Du Xianzhuo Zhang Wence Zhou Source Type: research

[Corrigendum] microRNA ‑181a‑5p functions as an oncogene in renal cell carcinoma
Mol Med Rep. 2024 Apr;29(4):58. doi: 10.3892/mmr.2024.13182. Epub 2024 Feb 16.ABSTRACTFollowing the publication of the above article and a corrigendum in 2018 that corrected details of the correspondence information for authors, errors made in Fig. 5 and the funding details (doi: 10.3892/mmr.2018.9117), an interested reader drew to the authors' attention that, in Fig. 6 on p. 8515 showing the results of cell migration and invasion assay experiments, a pair of data panels were overlapping, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the sam...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Yulin Lai Liwen Zhao Jia Hu Jing Quan Peijie Chen Jinling Xu Xin Guan Yongqing Lai Liangchao Ni Source Type: research

Research advances of MAL family members in tumorigenesis and tumor progression (Review)
Mol Med Rep. 2024 Apr;29(4):57. doi: 10.3892/mmr.2024.13181. Epub 2024 Feb 16.ABSTRACTThe myelin and lymphocyte protein (MAL) family is a novel gene family first identified and characterized in 2002. This family is comprised of seven members, including MAL, MAL2, plasmolipin, MALL, myeloid differentiation‑associated marker (MYADM), MYADML2 and CMTM8, which are located on different chromosomes. In addition to exhibiting extensive activity during transcytosis, the MAL family plays a vital role in the neurological, digestive, respiratory, genitourinary and other physiological systems. Furthermore, the intimate association b...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Mengyao Li Yan Du Xianzhuo Zhang Wence Zhou Source Type: research

[Corrigendum] microRNA ‑181a‑5p functions as an oncogene in renal cell carcinoma
Mol Med Rep. 2024 Apr;29(4):58. doi: 10.3892/mmr.2024.13182. Epub 2024 Feb 16.ABSTRACTFollowing the publication of the above article and a corrigendum in 2018 that corrected details of the correspondence information for authors, errors made in Fig. 5 and the funding details (doi: 10.3892/mmr.2018.9117), an interested reader drew to the authors' attention that, in Fig. 6 on p. 8515 showing the results of cell migration and invasion assay experiments, a pair of data panels were overlapping, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the sam...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Yulin Lai Liwen Zhao Jia Hu Jing Quan Peijie Chen Jinling Xu Xin Guan Yongqing Lai Liangchao Ni Source Type: research

Research advances of MAL family members in tumorigenesis and tumor progression (Review)
Mol Med Rep. 2024 Apr;29(4):57. doi: 10.3892/mmr.2024.13181. Epub 2024 Feb 16.ABSTRACTThe myelin and lymphocyte protein (MAL) family is a novel gene family first identified and characterized in 2002. This family is comprised of seven members, including MAL, MAL2, plasmolipin, MALL, myeloid differentiation‑associated marker (MYADM), MYADML2 and CMTM8, which are located on different chromosomes. In addition to exhibiting extensive activity during transcytosis, the MAL family plays a vital role in the neurological, digestive, respiratory, genitourinary and other physiological systems. Furthermore, the intimate association b...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Mengyao Li Yan Du Xianzhuo Zhang Wence Zhou Source Type: research

[Corrigendum] microRNA ‑181a‑5p functions as an oncogene in renal cell carcinoma
Mol Med Rep. 2024 Apr;29(4):58. doi: 10.3892/mmr.2024.13182. Epub 2024 Feb 16.ABSTRACTFollowing the publication of the above article and a corrigendum in 2018 that corrected details of the correspondence information for authors, errors made in Fig. 5 and the funding details (doi: 10.3892/mmr.2018.9117), an interested reader drew to the authors' attention that, in Fig. 6 on p. 8515 showing the results of cell migration and invasion assay experiments, a pair of data panels were overlapping, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the sam...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Yulin Lai Liwen Zhao Jia Hu Jing Quan Peijie Chen Jinling Xu Xin Guan Yongqing Lai Liangchao Ni Source Type: research

Research advances of MAL family members in tumorigenesis and tumor progression (Review)
Mol Med Rep. 2024 Apr;29(4):57. doi: 10.3892/mmr.2024.13181. Epub 2024 Feb 16.ABSTRACTThe myelin and lymphocyte protein (MAL) family is a novel gene family first identified and characterized in 2002. This family is comprised of seven members, including MAL, MAL2, plasmolipin, MALL, myeloid differentiation‑associated marker (MYADM), MYADML2 and CMTM8, which are located on different chromosomes. In addition to exhibiting extensive activity during transcytosis, the MAL family plays a vital role in the neurological, digestive, respiratory, genitourinary and other physiological systems. Furthermore, the intimate association b...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Mengyao Li Yan Du Xianzhuo Zhang Wence Zhou Source Type: research

[Corrigendum] microRNA ‑181a‑5p functions as an oncogene in renal cell carcinoma
Mol Med Rep. 2024 Apr;29(4):58. doi: 10.3892/mmr.2024.13182. Epub 2024 Feb 16.ABSTRACTFollowing the publication of the above article and a corrigendum in 2018 that corrected details of the correspondence information for authors, errors made in Fig. 5 and the funding details (doi: 10.3892/mmr.2018.9117), an interested reader drew to the authors' attention that, in Fig. 6 on p. 8515 showing the results of cell migration and invasion assay experiments, a pair of data panels were overlapping, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the sam...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Yulin Lai Liwen Zhao Jia Hu Jing Quan Peijie Chen Jinling Xu Xin Guan Yongqing Lai Liangchao Ni Source Type: research

Research advances of MAL family members in tumorigenesis and tumor progression (Review)
Mol Med Rep. 2024 Apr;29(4):57. doi: 10.3892/mmr.2024.13181. Epub 2024 Feb 16.ABSTRACTThe myelin and lymphocyte protein (MAL) family is a novel gene family first identified and characterized in 2002. This family is comprised of seven members, including MAL, MAL2, plasmolipin, MALL, myeloid differentiation‑associated marker (MYADM), MYADML2 and CMTM8, which are located on different chromosomes. In addition to exhibiting extensive activity during transcytosis, the MAL family plays a vital role in the neurological, digestive, respiratory, genitourinary and other physiological systems. Furthermore, the intimate association b...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Mengyao Li Yan Du Xianzhuo Zhang Wence Zhou Source Type: research

[Corrigendum] microRNA ‑181a‑5p functions as an oncogene in renal cell carcinoma
Mol Med Rep. 2024 Apr;29(4):58. doi: 10.3892/mmr.2024.13182. Epub 2024 Feb 16.ABSTRACTFollowing the publication of the above article and a corrigendum in 2018 that corrected details of the correspondence information for authors, errors made in Fig. 5 and the funding details (doi: 10.3892/mmr.2018.9117), an interested reader drew to the authors' attention that, in Fig. 6 on p. 8515 showing the results of cell migration and invasion assay experiments, a pair of data panels were overlapping, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the sam...
Source: Molecular Medicine Reports - February 16, 2024 Category: Molecular Biology Authors: Yulin Lai Liwen Zhao Jia Hu Jing Quan Peijie Chen Jinling Xu Xin Guan Yongqing Lai Liangchao Ni Source Type: research