[Retracted] Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK ‑JNK‑mediated AKT/mTOR signaling pathway
Mol Med Rep. 2024 Apr;29(4):60. doi: 10.3892/mmr.2024.13184. Epub 2024 Feb 23.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion and migration assay data shown in Fig. 1B and C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article had already been published prior to its ...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Shuping You Weihong Li Yun Guan Source Type: research
[Corrigendum] Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans
Mol Med Rep. 2024 Apr;29(4):62. doi: 10.3892/mmr.2024.13186. Epub 2024 Feb 23.ABSTRACTSubsequently to the publication of this paper, the authors' have realized that Fig. 2A on p. 3927 was published featuring an error; specifically, there was an unintentional duplication of one of the representative images chosen for the figure (the same image was selected to represent the 'BRCA/Normal' and 'Tumor/LUSC' experiments). Additionally, the sample numbers in Fig. 2A were also incorrect. The correct sample numbers are as follows: 3 samples of breast tissue, 12 samples of breast cancer tissue, 3 samples of normal cervical tissue, 9...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ying Liu Wenfeng Yu Peng Ren Ting Zhang Source Type: research
NLRP3 deficiency protects against acetaminophen ‑induced liver injury by inhibiting hepatocyte pyroptosis
Mol Med Rep. 2024 Apr;29(4):61. doi: 10.3892/mmr.2024.13185. Epub 2024 Feb 23.ABSTRACTAcetaminophen (APAP) overdose is the primary cause of drug‑induced acute liver failure in numerous Western countries. NLR family pyrin domain containing 3 (NLRP3) inflammasome activation serves a pivotal role in the pathogenesis of various forms of acute liver injury. However, the cellular source for NLRP3 induction and its involvement during APAP‑induced hepatotoxicity have not been thoroughly investigated. In the present study, hematoxylin and eosin staining was performed to assess histopathological changes of liver tissue. Immunohi...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Xinying Yuan Peng Chen Xiaoyu Luan Chaoqun Yu Longyu Miao Yaru Zuo Anxu Liu Tianyi Sun Guohu Di Source Type: research
Effect of prothymosin α on neuroplasticity following cerebral ischemia‑reperfusion injury
Mol Med Rep. 2024 Apr;29(4):59. doi: 10.3892/mmr.2024.13183. Epub 2024 Feb 23.ABSTRACTProthymosin α (ProT), a highly acidic nuclear protein with multiple cellular functions, has shown potential neuroprotective properties attributed to its anti‑necrotic and anti‑apoptotic activities. The present study aimed to investigate the beneficial effect of ProT on neuroplasticity after ischemia‑reperfusion injury and elucidate its underlying mechanism of action. Primary cortical neurons were either treated with ProT or overexpressing ProT by gene transfection and exposed to oxygen‑glucose deprivation for 2 h in vitro. Immuno...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ai-Chiang Lee Shih-Huang Tai Yi-Yun Chen Sheng-Yang Huang Chao-Liang Wu E-Jian Lee Source Type: research
[Retracted] Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK ‑JNK‑mediated AKT/mTOR signaling pathway
Mol Med Rep. 2024 Apr;29(4):60. doi: 10.3892/mmr.2024.13184. Epub 2024 Feb 23.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion and migration assay data shown in Fig. 1B and C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article had already been published prior to its ...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Shuping You Weihong Li Yun Guan Source Type: research
[Corrigendum] Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans
Mol Med Rep. 2024 Apr;29(4):62. doi: 10.3892/mmr.2024.13186. Epub 2024 Feb 23.ABSTRACTSubsequently to the publication of this paper, the authors' have realized that Fig. 2A on p. 3927 was published featuring an error; specifically, there was an unintentional duplication of one of the representative images chosen for the figure (the same image was selected to represent the 'BRCA/Normal' and 'Tumor/LUSC' experiments). Additionally, the sample numbers in Fig. 2A were also incorrect. The correct sample numbers are as follows: 3 samples of breast tissue, 12 samples of breast cancer tissue, 3 samples of normal cervical tissue, 9...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ying Liu Wenfeng Yu Peng Ren Ting Zhang Source Type: research
NLRP3 deficiency protects against acetaminophen ‑induced liver injury by inhibiting hepatocyte pyroptosis
Mol Med Rep. 2024 Apr;29(4):61. doi: 10.3892/mmr.2024.13185. Epub 2024 Feb 23.ABSTRACTAcetaminophen (APAP) overdose is the primary cause of drug‑induced acute liver failure in numerous Western countries. NLR family pyrin domain containing 3 (NLRP3) inflammasome activation serves a pivotal role in the pathogenesis of various forms of acute liver injury. However, the cellular source for NLRP3 induction and its involvement during APAP‑induced hepatotoxicity have not been thoroughly investigated. In the present study, hematoxylin and eosin staining was performed to assess histopathological changes of liver tissue. Immunohi...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Xinying Yuan Peng Chen Xiaoyu Luan Chaoqun Yu Longyu Miao Yaru Zuo Anxu Liu Tianyi Sun Guohu Di Source Type: research
Effect of prothymosin α on neuroplasticity following cerebral ischemia‑reperfusion injury
Mol Med Rep. 2024 Apr;29(4):59. doi: 10.3892/mmr.2024.13183. Epub 2024 Feb 23.ABSTRACTProthymosin α (ProT), a highly acidic nuclear protein with multiple cellular functions, has shown potential neuroprotective properties attributed to its anti‑necrotic and anti‑apoptotic activities. The present study aimed to investigate the beneficial effect of ProT on neuroplasticity after ischemia‑reperfusion injury and elucidate its underlying mechanism of action. Primary cortical neurons were either treated with ProT or overexpressing ProT by gene transfection and exposed to oxygen‑glucose deprivation for 2 h in vitro. Immuno...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ai-Chiang Lee Shih-Huang Tai Yi-Yun Chen Sheng-Yang Huang Chao-Liang Wu E-Jian Lee Source Type: research
[Retracted] Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK ‑JNK‑mediated AKT/mTOR signaling pathway
Mol Med Rep. 2024 Apr;29(4):60. doi: 10.3892/mmr.2024.13184. Epub 2024 Feb 23.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion and migration assay data shown in Fig. 1B and C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article had already been published prior to its ...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Shuping You Weihong Li Yun Guan Source Type: research
[Corrigendum] Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans
Mol Med Rep. 2024 Apr;29(4):62. doi: 10.3892/mmr.2024.13186. Epub 2024 Feb 23.ABSTRACTSubsequently to the publication of this paper, the authors' have realized that Fig. 2A on p. 3927 was published featuring an error; specifically, there was an unintentional duplication of one of the representative images chosen for the figure (the same image was selected to represent the 'BRCA/Normal' and 'Tumor/LUSC' experiments). Additionally, the sample numbers in Fig. 2A were also incorrect. The correct sample numbers are as follows: 3 samples of breast tissue, 12 samples of breast cancer tissue, 3 samples of normal cervical tissue, 9...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ying Liu Wenfeng Yu Peng Ren Ting Zhang Source Type: research
NLRP3 deficiency protects against acetaminophen ‑induced liver injury by inhibiting hepatocyte pyroptosis
Mol Med Rep. 2024 Apr;29(4):61. doi: 10.3892/mmr.2024.13185. Epub 2024 Feb 23.ABSTRACTAcetaminophen (APAP) overdose is the primary cause of drug‑induced acute liver failure in numerous Western countries. NLR family pyrin domain containing 3 (NLRP3) inflammasome activation serves a pivotal role in the pathogenesis of various forms of acute liver injury. However, the cellular source for NLRP3 induction and its involvement during APAP‑induced hepatotoxicity have not been thoroughly investigated. In the present study, hematoxylin and eosin staining was performed to assess histopathological changes of liver tissue. Immunohi...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Xinying Yuan Peng Chen Xiaoyu Luan Chaoqun Yu Longyu Miao Yaru Zuo Anxu Liu Tianyi Sun Guohu Di Source Type: research
Effect of prothymosin α on neuroplasticity following cerebral ischemia‑reperfusion injury
Mol Med Rep. 2024 Apr;29(4):59. doi: 10.3892/mmr.2024.13183. Epub 2024 Feb 23.ABSTRACTProthymosin α (ProT), a highly acidic nuclear protein with multiple cellular functions, has shown potential neuroprotective properties attributed to its anti‑necrotic and anti‑apoptotic activities. The present study aimed to investigate the beneficial effect of ProT on neuroplasticity after ischemia‑reperfusion injury and elucidate its underlying mechanism of action. Primary cortical neurons were either treated with ProT or overexpressing ProT by gene transfection and exposed to oxygen‑glucose deprivation for 2 h in vitro. Immuno...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ai-Chiang Lee Shih-Huang Tai Yi-Yun Chen Sheng-Yang Huang Chao-Liang Wu E-Jian Lee Source Type: research
[Retracted] Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK ‑JNK‑mediated AKT/mTOR signaling pathway
Mol Med Rep. 2024 Apr;29(4):60. doi: 10.3892/mmr.2024.13184. Epub 2024 Feb 23.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion and migration assay data shown in Fig. 1B and C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article had already been published prior to its ...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Shuping You Weihong Li Yun Guan Source Type: research
[Corrigendum] Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans
Mol Med Rep. 2024 Apr;29(4):62. doi: 10.3892/mmr.2024.13186. Epub 2024 Feb 23.ABSTRACTSubsequently to the publication of this paper, the authors' have realized that Fig. 2A on p. 3927 was published featuring an error; specifically, there was an unintentional duplication of one of the representative images chosen for the figure (the same image was selected to represent the 'BRCA/Normal' and 'Tumor/LUSC' experiments). Additionally, the sample numbers in Fig. 2A were also incorrect. The correct sample numbers are as follows: 3 samples of breast tissue, 12 samples of breast cancer tissue, 3 samples of normal cervical tissue, 9...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Ying Liu Wenfeng Yu Peng Ren Ting Zhang Source Type: research
NLRP3 deficiency protects against acetaminophen ‑induced liver injury by inhibiting hepatocyte pyroptosis
Mol Med Rep. 2024 Apr;29(4):61. doi: 10.3892/mmr.2024.13185. Epub 2024 Feb 23.ABSTRACTAcetaminophen (APAP) overdose is the primary cause of drug‑induced acute liver failure in numerous Western countries. NLR family pyrin domain containing 3 (NLRP3) inflammasome activation serves a pivotal role in the pathogenesis of various forms of acute liver injury. However, the cellular source for NLRP3 induction and its involvement during APAP‑induced hepatotoxicity have not been thoroughly investigated. In the present study, hematoxylin and eosin staining was performed to assess histopathological changes of liver tissue. Immunohi...
Source: Molecular Medicine Reports - February 23, 2024 Category: Molecular Biology Authors: Xinying Yuan Peng Chen Xiaoyu Luan Chaoqun Yu Longyu Miao Yaru Zuo Anxu Liu Tianyi Sun Guohu Di Source Type: research
