Circadian Genes and Risk of Prostate Cancer in the Prostate Cancer Prevention Trial
Conclusions: We did not find strong evidence that circadian gene variants influenced prostate cancer risk in men who were not on finasteride treatment. There were suggestive associations between NPAS2 variants and prostate cancer risk among men using finasteride, which warrants further investigations. This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 10, 2018 Category: Molecular Biology Authors: Lisa W. Chu, Cathee Till, Baiyu Yang, Catherine M. Tangen, Phyllis J. Goodman, Kai Yu, Yong Zhu, Summer Han, Ashraful M. Hoque, Christine Ambrosone, Ian Thompson, Robin Leach, Ann W. Hsing Tags: BRIEF COMMUNICATION Source Type: research
Genetic and Small Molecule Inhibition of Arylamine N ‐acetyltransferase 1 Reduces Anchorage‐Independent Growth in Human Breast Cancer Cell Line MDA‐MB‐231
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 9, 2018 Category: Molecular Biology Authors: Marcus W. Stepp, Mark A. Doll, Samantha M. Carlisle, J. Christopher States, David W. Hein Tags: RESEARCH ARTICLE Source Type: research
Genetic and small molecule inhibition of arylamine N ‐acetyltransferase 1 reduces anchorage‐independent growth in human breast cancer cell line MDA‐MB‐231
Molecular Carcinogenesis,Volume 57, Issue 4, Page 549-558, April 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 9, 2018 Category: Molecular Biology Source Type: research
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Molecular Carcinogenesis,Volume 57, Issue 4, Page 549-558, April 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 9, 2018 Category: Molecular Biology Source Type: research
FTO regulates the chemo ‐radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β‐catenin through mRNA demethylation
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 9, 2018 Category: Molecular Biology Authors: Shun Zhou, Zhou ‐Lan Bai, Di Xia, Zhi‐Jun Zhao, Ren Zhao, Yan‐Yang Wang, Hong Zhe Tags: RESEARCH ARTICLE Source Type: research
Issue Information ‐ Ed Board
(Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 5, 2018 Category: Molecular Biology Tags: Issue Information Source Type: research
Sohlh1 suppresses glioblastoma cell proliferation, migration, and invasion by inhibition of Wnt/ β‐catenin signaling
Glioblastoma (GBM) is the most aggressive and highly invasive type of astrocytic tumors. Despite advances in diagnosis and therapy, the prognosis and survival time remain poor. Identifying key mediators of tumor cell proliferation, migration, and invasion is crucial to the development of new and more effective therapies. In this paper, we report the novel role of Spermatogenesis‐ and oogenesis‐ specific basic helix‐loop‐helix transcription factor1 (Sohlh1) in the inhibition of Wnt/β‐catenin signaling and aggressive behaviors in GBM cells. Immunohistochemistry was performed to examine the expression of Sohlh1 and...
Source: Molecular Carcinogenesis - January 5, 2018 Category: Molecular Biology Authors: Xinyu Liu, Qing Gao, Na Zhao, Xiaoli Zhang, Weiwei Cui, Jinhao Sun, Jiang Fu, Jing Hao Tags: RESEARCH ARTICLE Source Type: research
Oncogene RNA helicase DDX6 promotes the process of c ‐Myc expression in gastric cancer cells
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - January 1, 2018 Category: Molecular Biology Authors: Kohei Taniguchi, Ayako Iwatsuki, Nobuhiko Sugito, Haruka Shinohara, Yuki Kuranaga, Yuki oshikawa, Toshihiro Tajirika, Manabu Futamura, Kazuhiro Yoshida, Kazuhisa Uchiyama, Yukihiro Akao Tags: RESEARCH ARTICLE Source Type: research
Mitochondrial dysfunction RAD51, and Ku80 proteolysis promote apoptotic effects of Dinaciclib in Bcl ‐xL silenced cells
In the present study, we investigated the effect of CDK inhibitors (ribociclib, palbociclib, seliciclib, AZD5438, and dinaciclib) on malignant human glioma cells for cell viability, apoptosis, oxidative stress, and mitochondrial function using various assays. None of the CDK inhibitors induced cell death at a clinically relevant concentration. However, low nanomolar concentrations of dinaciclib showed higher cytotoxic activity against Bcl‐xL silenced cells in a time‐ and concentration‐dependent manner. This effect was not seen with other CDK inhibitors. The apoptosis‐inducing capability of dinaciclib in Bcl‐xL si...
Source: Molecular Carcinogenesis - December 30, 2017 Category: Molecular Biology Authors: Daniel R. Premkumar, Esther P. Jane, Swetha Thambireddy, Philip A. Sutera, Jonathon M. Cavaleri, Ian F. Pollack Tags: RESEARCH ARTICLE Source Type: research
Suppression of STAT3 NH2 ‐Terminal Domain Chemosensitizes Medulloblastoma Cells by Activation of Protein Inhibitor of Activated STAT3 via de‐repression by MicroRNA‐21
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - December 27, 2017 Category: Molecular Biology Authors: Sutapa Ray, Don W Coulter, Shawn D Gray, Jason A Sughroue, Shrabasti Roychoudhury, Erin M McIntyre, Nagendra K Chaturvedi, Kishor K Bhakat, Shantaram S Joshi, Timothy R McGuire, John G Sharp Tags: RESEARCH ARTICLE Source Type: research
Inhibition of autophagy potentiates the anti ‐metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - December 27, 2017 Category: Molecular Biology Authors: Huimin Wang, Limin Wang, Limin Cao, Qicheng Zhang, Qianqian Song, Zhaowei Meng, Xiang Wu, Ke Xu Tags: RESEARCH ARTICLE Source Type: research
Suppression of STAT3 NH2 ‐terminal domain chemosensitizes medulloblastoma cells by activation of protein inhibitor of activated STAT3 via de‐repression by microRNA‐21
Molecular Carcinogenesis,Volume 57, Issue 4, Page 536-548, April 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - December 27, 2017 Category: Molecular Biology Source Type: research
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Molecular Carcinogenesis,Volume 57, Issue 4, Page 536-548, April 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - December 27, 2017 Category: Molecular Biology Source Type: research
Inhibition of autophagy potentiates the anti ‐metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells
Molecular Carcinogenesis,Volume 57, Issue 4, Page 522-535, April 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - December 26, 2017 Category: Molecular Biology Source Type: research
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Molecular Carcinogenesis,Volume 57, Issue 4, Page 522-535, April 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - December 26, 2017 Category: Molecular Biology Source Type: research
