Whole genome sequencing analysis of Komagataeibacter nataicola reveals its potential in food waste valorisation for cellulose production
CONCLUSION: A more comprehensive genome study of K. nataicola may shed light into biological pathway in BC productivity as well as benefit the analysis of metabolites generated and understanding of biological and chemical interactions in BC production later.PMID:38600404 | DOI:10.1007/s11033-024-09492-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Muhammad Irhamni Haziqi Nasharudin Shing-Wei Siew Hajar Fauzan Ahmad Nazira Mahmud Source Type: research
"Decoding inflammation: glycoprotein a repetition predominant, microRNA-142-3-p, and metastasis associated lung adenocarcinoma transcript 1: as novel inflammatory biomarkers of inflammatory bowel disease"
CONCLUSIONS: Dysregulation of GARP, MALAT1, and miR-142-3p likely contributes to inflammation in IBD by reducing TGF-β. MALAT1 is linked to smoking and age-related changes. These genes have potential as diagnostic markers or therapeutic targets for personalized IBD treatment.PMID:38598005 | DOI:10.1007/s11033-024-09475-9 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Mohammad Reza Lahimchi Mousa Mohammadnia-Afrouzi Rasoul Baharlou Dariush Haghmorad Seyed Hassan Abedi Delaram Arjmandi Masoomeh Hosseini Bahman Yousefi Source Type: research
Current research on the interaction between Helicobacter pylori and macrophages
Mol Biol Rep. 2024 Apr 10;51(1):497. doi: 10.1007/s11033-024-09395-8.ABSTRACTHelicobacter pylori (H. pylori) is a gram-negative bacteria with a worldwide infection rate of 50%, known to induce gastritis, ulcers and gastric cancer. The interplay between H. pylori and immune cells within the gastric mucosa is pivotal in the pathogenesis of H. pylori-related disease. Following H. pylori infection, there is an observed increase in gastric mucosal macrophages, which are associated with the progression of gastritis. H. pylori elicits macrophage polarization, releases cytokines, reactive oxygen species (ROS) and nitric oxide (NO)...
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Yan-Fei Wei Si-An Xie Shu-Tian Zhang Source Type: research
BRAF and RET polymorphism association with thyroid cancer risk, a preliminary study from Khyber Pakhtunkhwa population
CONCLUSION: In conclusion, this study emphasizes the significant association between BRAF polymorphism and thyroid cancer risk, while RET polymorphism showed a less pronounced impact. Further validation using larger and specific datasets is essential to establish conclusive results.PMID:38598020 | DOI:10.1007/s11033-024-09480-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Maryam Batool Najeeb Ullah Khan Hamza Khan Mikhlid H Almutairi Ijaz Ali Brian D Adams Source Type: research
Identification of a novel intronic variant of ATP6V0A2 in a Han-Chinese family with cutis laxa
CONCLUSIONS: In this study, it was identified that ATP6V0A2 gene c. 117 + 5G > T may be the cause of the disease. The non-canonical splicing variants of ATP6V0A2 gene were rarely reported in the past, and this variant expanded the variants spectrum of the gene. The functional study of minigene assay plays a certain role in improving the level of evidence for the pathogenicity of splicing variants, which lays a foundation for prenatal counseling and follow-up gene therapy.PMID:38598037 | DOI:10.1007/s11033-024-09446-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Ying Zhang Mei Sun Na Li Yiran Zhao Fang Zhang Jianbo Shu Yang Liu Chunquan Cai Source Type: research
Silver nanoparticle-induced in vitro flowering in Dendrocalamus strictus (Roxb.) nees and genetic fidelity assessment of regenerants using molecular markers
CONCLUSIONS: It can be inferred that the incorporation of AgNPs during the shoot proliferation phase has the potential to stimulate in vitro flowering in D. strictus. This finding could provide valuable insights into innovative strategies for enhancing crop productivity and genetic manipulation for accelerated breeding and agricultural advancement.PMID:38598057 | DOI:10.1007/s11033-024-09472-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Bharat Singh Rajput M Manokari Nitin J Solanki Dulam Sandhya Mohammad Faisal Abdulrahman A Alatar Mahipal S Shekhawat Source Type: research
Aerobic physical training reduces severe asthma phenotype involving kinins pathway
CONCLUSION: These findings indicate that APT inhibits the severe asthma phenotype by targeting kinin signaling.PMID:38598121 | DOI:10.1007/s11033-024-09474-w (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Maysa Alves Rodrigues Brandao-Rangel Renilson Moraes-Ferreira Anamei Silva-Reis Victor Hugo Souza-Palmeira Francine Maria Almeida Fabiana Regina da Silva Olimpio Carlos Rocha Oliveira Nilsa Regina Damaceno-Rodrigues Jo ão Bosco Pesquero Leonardo Martin F Source Type: research
Whole genome sequencing analysis of Komagataeibacter nataicola reveals its potential in food waste valorisation for cellulose production
CONCLUSION: A more comprehensive genome study of K. nataicola may shed light into biological pathway in BC productivity as well as benefit the analysis of metabolites generated and understanding of biological and chemical interactions in BC production later.PMID:38600404 | DOI:10.1007/s11033-024-09492-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Muhammad Irhamni Haziqi Nasharudin Shing-Wei Siew Hajar Fauzan Ahmad Nazira Mahmud Source Type: research
"Decoding inflammation: glycoprotein a repetition predominant, microRNA-142-3-p, and metastasis associated lung adenocarcinoma transcript 1: as novel inflammatory biomarkers of inflammatory bowel disease"
CONCLUSIONS: Dysregulation of GARP, MALAT1, and miR-142-3p likely contributes to inflammation in IBD by reducing TGF-β. MALAT1 is linked to smoking and age-related changes. These genes have potential as diagnostic markers or therapeutic targets for personalized IBD treatment.PMID:38598005 | DOI:10.1007/s11033-024-09475-9 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Mohammad Reza Lahimchi Mousa Mohammadnia-Afrouzi Rasoul Baharlou Dariush Haghmorad Seyed Hassan Abedi Delaram Arjmandi Masoomeh Hosseini Bahman Yousefi Source Type: research
Current research on the interaction between Helicobacter pylori and macrophages
Mol Biol Rep. 2024 Apr 10;51(1):497. doi: 10.1007/s11033-024-09395-8.ABSTRACTHelicobacter pylori (H. pylori) is a gram-negative bacteria with a worldwide infection rate of 50%, known to induce gastritis, ulcers and gastric cancer. The interplay between H. pylori and immune cells within the gastric mucosa is pivotal in the pathogenesis of H. pylori-related disease. Following H. pylori infection, there is an observed increase in gastric mucosal macrophages, which are associated with the progression of gastritis. H. pylori elicits macrophage polarization, releases cytokines, reactive oxygen species (ROS) and nitric oxide (NO)...
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Yan-Fei Wei Si-An Xie Shu-Tian Zhang Source Type: research
BRAF and RET polymorphism association with thyroid cancer risk, a preliminary study from Khyber Pakhtunkhwa population
CONCLUSION: In conclusion, this study emphasizes the significant association between BRAF polymorphism and thyroid cancer risk, while RET polymorphism showed a less pronounced impact. Further validation using larger and specific datasets is essential to establish conclusive results.PMID:38598020 | DOI:10.1007/s11033-024-09480-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Maryam Batool Najeeb Ullah Khan Hamza Khan Mikhlid H Almutairi Ijaz Ali Brian D Adams Source Type: research
Identification of a novel intronic variant of ATP6V0A2 in a Han-Chinese family with cutis laxa
CONCLUSIONS: In this study, it was identified that ATP6V0A2 gene c. 117 + 5G > T may be the cause of the disease. The non-canonical splicing variants of ATP6V0A2 gene were rarely reported in the past, and this variant expanded the variants spectrum of the gene. The functional study of minigene assay plays a certain role in improving the level of evidence for the pathogenicity of splicing variants, which lays a foundation for prenatal counseling and follow-up gene therapy.PMID:38598037 | DOI:10.1007/s11033-024-09446-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Ying Zhang Mei Sun Na Li Yiran Zhao Fang Zhang Jianbo Shu Yang Liu Chunquan Cai Source Type: research
Silver nanoparticle-induced in vitro flowering in Dendrocalamus strictus (Roxb.) nees and genetic fidelity assessment of regenerants using molecular markers
CONCLUSIONS: It can be inferred that the incorporation of AgNPs during the shoot proliferation phase has the potential to stimulate in vitro flowering in D. strictus. This finding could provide valuable insights into innovative strategies for enhancing crop productivity and genetic manipulation for accelerated breeding and agricultural advancement.PMID:38598057 | DOI:10.1007/s11033-024-09472-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Bharat Singh Rajput M Manokari Nitin J Solanki Dulam Sandhya Mohammad Faisal Abdulrahman A Alatar Mahipal S Shekhawat Source Type: research
Aerobic physical training reduces severe asthma phenotype involving kinins pathway
CONCLUSION: These findings indicate that APT inhibits the severe asthma phenotype by targeting kinin signaling.PMID:38598121 | DOI:10.1007/s11033-024-09474-w (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Maysa Alves Rodrigues Brandao-Rangel Renilson Moraes-Ferreira Anamei Silva-Reis Victor Hugo Souza-Palmeira Francine Maria Almeida Fabiana Regina da Silva Olimpio Carlos Rocha Oliveira Nilsa Regina Damaceno-Rodrigues Jo ão Bosco Pesquero Leonardo Martin F Source Type: research
Whole genome sequencing analysis of Komagataeibacter nataicola reveals its potential in food waste valorisation for cellulose production
CONCLUSION: A more comprehensive genome study of K. nataicola may shed light into biological pathway in BC productivity as well as benefit the analysis of metabolites generated and understanding of biological and chemical interactions in BC production later.PMID:38600404 | DOI:10.1007/s11033-024-09492-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 10, 2024 Category: Molecular Biology Authors: Muhammad Irhamni Haziqi Nasharudin Shing-Wei Siew Hajar Fauzan Ahmad Nazira Mahmud Source Type: research
