Feature impact assessment: a new score to identify relevant metabolomics features in artificial neural networks using validated labels
ConclusionFIA is a novel score ranking feature impact, helping interpreting ANN in the metabolomics field. (Source: Metabolomics)
Source: Metabolomics - March 25, 2023 Category: Biology Source Type: research

Aberrations in the early pregnancy serum metabolic profile in women with prediabetes at two years postpartum
ConclusionElevated serum concentrations of small HDL particles in early pregnancy associate with prediabetes and insulin resistance at two years postpartum. The serum metabolic profile during pregnancy might be used to identify women at increased risk for type 2 diabetes. (Source: Metabolomics)
Source: Metabolomics - March 24, 2023 Category: Biology Source Type: research

No skin off your back: the sampling and extraction of sebum for metabolomics
ConclusionSebum has a huge potential beyond skin research and understanding how one ’s physiological state affects or reflects on the skin metabolome via the sebaceous glands itself or by interactions with sebaceous secretion, will open doors for simpler biomonitoring. Sebum acts as a sink to environmental metabolites and has applications awaiting to be explored, such as biosecur ity, cross-border migration, localised exposure to harmful substances, and high-throughput population screening. These applications will be possible with rapid advances in volatile headspace and lipidomics method development as well as the abili...
Source: Metabolomics - March 24, 2023 Category: Biology Source Type: research

Aberrations in the early pregnancy serum metabolic profile in women with prediabetes at two years postpartum
ConclusionElevated serum concentrations of small HDL particles in early pregnancy associate with prediabetes and insulin resistance at two years postpartum. The serum metabolic profile during pregnancy might be used to identify women at increased risk for type 2 diabetes. (Source: Metabolomics)
Source: Metabolomics - March 24, 2023 Category: Biology Source Type: research

Correction: Model-driven data curation pipeline for LC –MS-based untargeted metabolomics
(Source: Metabolomics)
Source: Metabolomics - March 16, 2023 Category: Biology Source Type: research

Mass spectrometry DDA parameters and global coverage of the metabolome: Spectral molecular networks of momordica cardiospermoides plants
ConclusionContributing to ongoing efforts and conversations on improving DDA strategies, this study proposes a framework in which multiple DDA parameters are utilized to increase the coverage of ions acquired and improve the global coverage of MN, propagated annotations, and the chemical classification performed. (Source: Metabolomics)
Source: Metabolomics - March 15, 2023 Category: Biology Source Type: research

Impact of in vitro phytohormone treatments on the metabolome of the leafy liverwort Radula complanata (L.) Dumort
ConclusionExogenous phytohormone application caused clear metabolic shifts inRadula complanata that deviate from the responses of vascular plants. Further identification of the selected metabolite features can reveal metabolic biomarkers unique to liverworts and provide more insight into liverwort stress responses. (Source: Metabolomics)
Source: Metabolomics - March 9, 2023 Category: Biology Source Type: research

Bioherbicidal Activity and Metabolic Profiling of Allelopathic Metabolites of Three Cassia species using UPLC-qTOF-MS/MS and Molecular Networking
Conclusion: The present study recommends further evaluation ofCassia extracts as a potential source of allelopathic compounds in agricultural systems. (Source: Metabolomics)
Source: Metabolomics - March 9, 2023 Category: Biology Source Type: research

Impact of in vitro phytohormone treatments on the metabolome of the leafy liverwort Radula complanata (L.) Dumort
ConclusionExogenous phytohormone application caused clear metabolic shifts inRadula complanata that deviate from the responses of vascular plants. Further identification of the selected metabolite features can reveal metabolic biomarkers unique to liverworts and provide more insight into liverwort stress responses. (Source: Metabolomics)
Source: Metabolomics - March 9, 2023 Category: Biology Source Type: research

Bioherbicidal Activity and Metabolic Profiling of Allelopathic Metabolites of Three Cassia species using UPLC-qTOF-MS/MS and Molecular Networking
Conclusion: The present study recommends further evaluation ofCassia extracts as a potential source of allelopathic compounds in agricultural systems. (Source: Metabolomics)
Source: Metabolomics - March 9, 2023 Category: Biology Source Type: research

Model-driven data curation pipeline for LC –MS-based untargeted metabolomics
ConclusionThe developed pipeline allowed confirming data robustness by comparing the experimental results with expected values predicted by the model. New quality control practices were introduced to assess the analytical quality of data. (Source: Metabolomics)
Source: Metabolomics - March 1, 2023 Category: Biology Source Type: research