Assessment of association between the rs2270637 polymorphism of VMAT1 gene and risk of bipolar and major depressive disorders
ConclusionThus, the rs2270637 SNP cannot be regarded as a risk locus for BPD or MDD in Iranian population. (Source: Meta Gene)
Source: Meta Gene - February 11, 2020 Category: Genetics & Stem Cells Source Type: research
Evaluate the gene expression of TPT1, EDN3, and ANO7 in prostate cancer tissues and their relation with age, tumor stage and family history
ConclusionsAccording to the above, we are approved a potential of monitoring and screening PCa by targeting TPT1, EDN3, and ANO7 genes expression approach. (Source: Meta Gene)
Source: Meta Gene - February 11, 2020 Category: Genetics & Stem Cells Source Type: research
Intellectual disability; an example of not relying on karyotype or array comparative genomic hybridization alone
Publication date: Available online 7 February 2020Source: Meta GeneAuthor(s): Farhad Khadivi zand, Mohammad Shariati, Amirsaeed Sabeti Aghabozorgi, Sohelia Saberi, Haniyeh Khatib Astaneh, Atefeh Ahmadzadeh, Zohreh Samie, Parisa Ansari, Ariane Sadr Nabavi, Reza Jafarzadeh-EsfehaniAbstractIntellectual disability (ID) is a heterogeneous disorder which could have different etiologies. Among these etiologies, genetic causes are important issues. Genetic and pediatric guidelines have suggested using comparative genomic hybridization (CGH) as the first tire test for the diagnosis of such patients. However, in some ID cases such a...
Source: Meta Gene - February 8, 2020 Category: Genetics & Stem Cells Source Type: research
Dysregulation of cell-free long non-coding RNAs (NEAT2, CTC-471J1.2 and lnc-DC) in Egyptian systemic lupus and lupus nephritis patients
Publication date: Available online 7 February 2020Source: Meta GeneAuthor(s): Amany A. Saleh, Heba E. Kasem, Enas Zahran, Sally M. El-HefnawyAbstractSystemic lupus erythematosus (SLE) is a multisystem autoimmune disorder; lupus nephritis (LN) is the main cause of disability and death in SLE patients. Although long noncoding RNAs (lncRNAs) lack a protein-coding ability, they have a significant role in the regulation of gene expression. We aimed to evaluate cell-free lncRNAs (NEAT2, CTC-471 J1.2 and lnc-DC) as biomarkers for SLE and LN. Quantification of the expression level of cell-free lncRNAs (NEAT2, CTC-471J1.2 and lnc...
Source: Meta Gene - February 8, 2020 Category: Genetics & Stem Cells Source Type: research
Association of FCRL3 rs7528684 polymorphism with risk of Hashimoto's thyroiditis in Iranian patients
ConclusionsThese data showed an association between FCRL3 CC genotype and C allele of rs7528684 SNP and susceptibility to HT, supporting the important role of FCRL3 variants in HT development. (Source: Meta Gene)
Source: Meta Gene - February 5, 2020 Category: Genetics & Stem Cells Source Type: research
