Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research
