The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil
Mem Inst Oswaldo Cruz. 2024 Feb 12;119:e230208. doi: 10.1590/0074-02760230208. eCollection 2024.ABSTRACTTwenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include ...
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Rodrigo Almeida-Paes Antonio Carlos Francesconi do Valle Dayvison Francis Saraiva Freitas Priscila Marques de Macedo Rosely Maria Zancop é-Oliveira Maria Clara Gutierrez-Galhardo Source Type: research

Simple and promising paper-based electrochemical platform for serological detection of American tegumentary leishmaniasis
CONCLUSIONS: Our platform could allow the diagnosis, management, and monitoring of leishmaniasis while being an extremely simple and environmentally friendly technology.PMID:38359306 | PMC:PMC10868376 | DOI:10.1590/0074-02760230149 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Daniela E Barraza Paula I Nanni Mar ía E Bracamonte Roberto E Chaile Carla B Goy Leonardo Acu ña Jorge D Marco Rossana E Madrid Source Type: research

The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil
Mem Inst Oswaldo Cruz. 2024 Feb 12;119:e230208. doi: 10.1590/0074-02760230208. eCollection 2024.ABSTRACTTwenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include ...
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Rodrigo Almeida-Paes Antonio Carlos Francesconi do Valle Dayvison Francis Saraiva Freitas Priscila Marques de Macedo Rosely Maria Zancop é-Oliveira Maria Clara Gutierrez-Galhardo Source Type: research

Simple and promising paper-based electrochemical platform for serological detection of American tegumentary leishmaniasis
CONCLUSIONS: Our platform could allow the diagnosis, management, and monitoring of leishmaniasis while being an extremely simple and environmentally friendly technology.PMID:38359306 | PMC:PMC10868376 | DOI:10.1590/0074-02760230149 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Daniela E Barraza Paula I Nanni Mar ía E Bracamonte Roberto E Chaile Carla B Goy Leonardo Acu ña Jorge D Marco Rossana E Madrid Source Type: research

The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil
Mem Inst Oswaldo Cruz. 2024 Feb 12;119:e230208. doi: 10.1590/0074-02760230208. eCollection 2024.ABSTRACTTwenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include ...
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Rodrigo Almeida-Paes Antonio Carlos Francesconi do Valle Dayvison Francis Saraiva Freitas Priscila Marques de Macedo Rosely Maria Zancop é-Oliveira Maria Clara Gutierrez-Galhardo Source Type: research

Simple and promising paper-based electrochemical platform for serological detection of American tegumentary leishmaniasis
CONCLUSIONS: Our platform could allow the diagnosis, management, and monitoring of leishmaniasis while being an extremely simple and environmentally friendly technology.PMID:38359306 | PMC:PMC10868376 | DOI:10.1590/0074-02760230149 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Daniela E Barraza Paula I Nanni Mar ía E Bracamonte Roberto E Chaile Carla B Goy Leonardo Acu ña Jorge D Marco Rossana E Madrid Source Type: research

The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil
Mem Inst Oswaldo Cruz. 2024 Feb 12;119:e230208. doi: 10.1590/0074-02760230208. eCollection 2024.ABSTRACTTwenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include ...
Source: Memorias do Instituto Oswaldo Cruz - February 15, 2024 Category: Infectious Diseases Authors: Rodrigo Almeida-Paes Antonio Carlos Francesconi do Valle Dayvison Francis Saraiva Freitas Priscila Marques de Macedo Rosely Maria Zancop é-Oliveira Maria Clara Gutierrez-Galhardo Source Type: research

Leishmania (Leishmania) infantum DNA detection in Nyssomyia neivai in Vale do Ribeira, Paran á, Brazil
CONCLUSIONS: The detection of L. infantum in Ny. neivai draws attention due to its abundance and anthropophily in the State of Paraná. Moreover, this finding is considered as an alert and suggests that the vector competence of Ny. neivai and the criteria for its incrimination should be carried out, given its wide distribution in southern of Brazil.PMID:38324879 | PMC:PMC10836809 | DOI:10.1590/0074-02760230173 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 7, 2024 Category: Infectious Diseases Authors: Let ícia Cristina Morelli Daniela de Pita-Pereira Constan ça Britto Thais de Ara újo-Pereira Lucas Alexandre Farias de Souza Kelly de Oliveira Germano Andrey Jos é de Andrade Magda Clara Vieira da Costa-Ribeiro Source Type: research

Characterisation of an area of coexistent visceral and cutaneous leishmaniasis transmission in the State of Piau í, Brazil
CONCLUSION: Our results indicate the presence of risk areas for ACL and AVL in the municipality of Altos and highlight the importance of entomological surveillance to further understand a possible role of Lu. longipalpis in ACL transmission.PMID:38324880 | PMC:PMC10841424 | DOI:10.1590/0074-02760230181 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 7, 2024 Category: Infectious Diseases Authors: Silvia Alc ântara Vasconcelos Raimundo Leoberto Torres de Sousa En éas Costa Junior Jo ão Paulo Diniz E Souza Diane Cavalcante Ant ônio Carlos Lima da Silva Ivete Lopes de Mendon ça Jacenir Mallet Clarissa Romero Teixeira Guilherme Loureiro Werneck T Source Type: research

Leishmania (Leishmania) infantum DNA detection in Nyssomyia neivai in Vale do Ribeira, Paran á, Brazil
CONCLUSIONS: The detection of L. infantum in Ny. neivai draws attention due to its abundance and anthropophily in the State of Paraná. Moreover, this finding is considered as an alert and suggests that the vector competence of Ny. neivai and the criteria for its incrimination should be carried out, given its wide distribution in southern of Brazil.PMID:38324879 | PMC:PMC10836809 | DOI:10.1590/0074-02760230173 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 7, 2024 Category: Infectious Diseases Authors: Let ícia Cristina Morelli Daniela de Pita-Pereira Constan ça Britto Thais de Ara újo-Pereira Lucas Alexandre Farias de Souza Kelly de Oliveira Germano Andrey Jos é de Andrade Magda Clara Vieira da Costa-Ribeiro Source Type: research

Characterisation of an area of coexistent visceral and cutaneous leishmaniasis transmission in the State of Piau í, Brazil
CONCLUSION: Our results indicate the presence of risk areas for ACL and AVL in the municipality of Altos and highlight the importance of entomological surveillance to further understand a possible role of Lu. longipalpis in ACL transmission.PMID:38324880 | PMC:PMC10841424 | DOI:10.1590/0074-02760230181 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - February 7, 2024 Category: Infectious Diseases Authors: Silvia Alc ântara Vasconcelos Raimundo Leoberto Torres de Sousa En éas Costa Junior Jo ão Paulo Diniz E Souza Diane Cavalcante Ant ônio Carlos Lima da Silva Ivete Lopes de Mendon ça Jacenir Mallet Clarissa Romero Teixeira Guilherme Loureiro Werneck T Source Type: research

The absence of eosinophils is associated with early metastatic lesions in Leishmania amazonensis-infected mice
CONCLUSION: These results suggest a protective role of eosinophils in delaying the disease caused by L. amazonensis, although several limitations of this mice strain must be considered.PMID:38198296 | PMC:PMC10777375 | DOI:10.1590/0074-02760220242 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - January 10, 2024 Category: Infectious Diseases Authors: Greg ório Guilherme Almeida Tassiane Ass íria Martins Luehring Pierre Henrique de Menezes Paix ão Rodrigo Pedro Soares Andr é Luís Branco de Barros Rubens Lima do Monte-Neto Wagner Luiz Tafuri Deborah Aparecida Negr ão-Corrêa Ricardo Gon çalves Source Type: research

Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research

Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
CONCLUSIONS: Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR.PMID:38126526 | PMC:PMC10727046 | DOI:10.1590/0074-02760230115 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Ana Carolina Bastos de Lima Veronica Gon çalves Mendes Roberto Rodrigues Ferreira Lindice Mitie Nisimura Samuel Iwao Maia Horita Henrique H Veloso Andr éa R Costa Gilberto Marcelo S da Silva Luiz Henrique C Sangenis Marcelo T Holanda Lorena Rimolo Ademi Source Type: research

Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain
CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research