Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report
CONCLUSIONS: This case demonstrates that Long COVID-19 may develop even after mild disease due to SARS-CoV-2 in fully vaccinated and boosted individuals without comorbidities. Continued monitoring of new SARS-CoV-2 lineages and associated clinical outcomes is warranted. Measures to prevent infection should continue to be implemented including development of new vaccines and antivirals effective against novel variants.PMID:37851721 | PMC:PMC10581372 | DOI:10.1590/0074-02760230069 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Ot ávio Espíndola Paola C Resende Lusiele Guaraldo Guilherme Amaral Calvet Trevon L Fuller Stephanie Lema Suarez Penetra Heloisa Ferreira Pinto Santos Anielle Pina-Costa Michele Fernanda Borges da Silva Isabella Campos Vargas Moraes Fernando Medeiros Ji Source Type: research
Differences in responses to the intracellular macrophage environment between Mycobacterium bovis BCG vaccine strains Moreau and Pasteur
CONCLUSION: Overall, our results show that, compared to Pasteur, BCG Moreau has increased fitness and better endurance in the harsh intracellular environment, also regulating anti-microbial responses (lower IL-1b and MCP-1). These findings contribute to the understanding of the physiology of BCG Moreau and Pasteur in response to the intraphagosomal environment in a THP-1 macrophage model.PMID:37851722 | PMC:PMC10581373 | DOI:10.1590/0074-02760230070 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Paloma Rezende Corr êa Marcos Gustavo Araujo Schwarz Renata Monteiro Maia F átima Maria Figueroa Vergara Milton Oz ório Moraes Leila Mendon ça-Lima Source Type: research
Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report
CONCLUSIONS: This case demonstrates that Long COVID-19 may develop even after mild disease due to SARS-CoV-2 in fully vaccinated and boosted individuals without comorbidities. Continued monitoring of new SARS-CoV-2 lineages and associated clinical outcomes is warranted. Measures to prevent infection should continue to be implemented including development of new vaccines and antivirals effective against novel variants.PMID:37851721 | PMC:PMC10581372 | DOI:10.1590/0074-02760230069 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Ot ávio Espíndola Paola C Resende Lusiele Guaraldo Guilherme Amaral Calvet Trevon L Fuller Stephanie Lema Suarez Penetra Heloisa Ferreira Pinto Santos Anielle Pina-Costa Michele Fernanda Borges da Silva Isabella Campos Vargas Moraes Fernando Medeiros Ji Source Type: research
Differences in responses to the intracellular macrophage environment between Mycobacterium bovis BCG vaccine strains Moreau and Pasteur
CONCLUSION: Overall, our results show that, compared to Pasteur, BCG Moreau has increased fitness and better endurance in the harsh intracellular environment, also regulating anti-microbial responses (lower IL-1b and MCP-1). These findings contribute to the understanding of the physiology of BCG Moreau and Pasteur in response to the intraphagosomal environment in a THP-1 macrophage model.PMID:37851722 | PMC:PMC10581373 | DOI:10.1590/0074-02760230070 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Paloma Rezende Corr êa Marcos Gustavo Araujo Schwarz Renata Monteiro Maia F átima Maria Figueroa Vergara Milton Oz ório Moraes Leila Mendon ça-Lima Source Type: research
Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report
CONCLUSIONS: This case demonstrates that Long COVID-19 may develop even after mild disease due to SARS-CoV-2 in fully vaccinated and boosted individuals without comorbidities. Continued monitoring of new SARS-CoV-2 lineages and associated clinical outcomes is warranted. Measures to prevent infection should continue to be implemented including development of new vaccines and antivirals effective against novel variants.PMID:37851721 | DOI:10.1590/0074-02760230069 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Ot ávio Espíndola Paola C Resende Lusiele Guaraldo Guilherme Amaral Calvet Trevon L Fuller Stephanie Lema Suarez Penetra Heloisa Ferreira Pinto Santos Anielle Pina-Costa Michele Fernanda Borges da Silva Isabella Campos Vargas Moraes Fernando Medeiros Ji Source Type: research
Differences in responses to the intracellular macrophage environment between Mycobacterium bovis BCG vaccine strains Moreau and Pasteur
CONCLUSION: Overall, our results show that, compared to Pasteur, BCG Moreau has increased fitness and better endurance in the harsh intracellular environment, also regulating anti-microbial responses (lower IL-1b and MCP-1). These findings contribute to the understanding of the physiology of BCG Moreau and Pasteur in response to the intraphagosomal environment in a THP-1 macrophage model.PMID:37851722 | DOI:10.1590/0074-02760230070 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Paloma Rezende Corr êa Marcos Gustavo Araujo Schwarz Renata Monteiro Maia F átima Maria Figueroa Vergara Milton Oz ório Moraes Leila Mendon ça-Lima Source Type: research
Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report
CONCLUSIONS: This case demonstrates that Long COVID-19 may develop even after mild disease due to SARS-CoV-2 in fully vaccinated and boosted individuals without comorbidities. Continued monitoring of new SARS-CoV-2 lineages and associated clinical outcomes is warranted. Measures to prevent infection should continue to be implemented including development of new vaccines and antivirals effective against novel variants.PMID:37851721 | DOI:10.1590/0074-02760230069 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Ot ávio Espíndola Paola C Resende Lusiele Guaraldo Guilherme Amaral Calvet Trevon L Fuller Stephanie Lema Suarez Penetra Heloisa Ferreira Pinto Santos Anielle Pina-Costa Michele Fernanda Borges da Silva Isabella Campos Vargas Moraes Fernando Medeiros Ji Source Type: research
Differences in responses to the intracellular macrophage environment between Mycobacterium bovis BCG vaccine strains Moreau and Pasteur
CONCLUSION: Overall, our results show that, compared to Pasteur, BCG Moreau has increased fitness and better endurance in the harsh intracellular environment, also regulating anti-microbial responses (lower IL-1b and MCP-1). These findings contribute to the understanding of the physiology of BCG Moreau and Pasteur in response to the intraphagosomal environment in a THP-1 macrophage model.PMID:37851722 | DOI:10.1590/0074-02760230070 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Paloma Rezende Corr êa Marcos Gustavo Araujo Schwarz Renata Monteiro Maia F átima Maria Figueroa Vergara Milton Oz ório Moraes Leila Mendon ça-Lima Source Type: research
Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Mem Inst Oswaldo Cruz. 2023 Oct 9;118:e230044. doi: 10.1590/0074-02760230044. eCollection 2023.ABSTRACTLipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell types in the...
Source: Memorias do Instituto Oswaldo Cruz - October 11, 2023 Category: Infectious Diseases Authors: Suelen Silva Gomes Dias Tamires Cunha-Fernandes Vinicius Cardoso Soares Cec ília Jg de Almeida Patricia T Bozza Source Type: research
Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Mem Inst Oswaldo Cruz. 2023 Oct 9;118:e230044. doi: 10.1590/0074-02760230044. eCollection 2023.ABSTRACTLipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell types in the...
Source: Memorias do Instituto Oswaldo Cruz - October 11, 2023 Category: Infectious Diseases Authors: Suelen Silva Gomes Dias Tamires Cunha-Fernandes Vinicius Cardoso Soares Cec ília Jg de Almeida Patricia T Bozza Source Type: research
Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Mem Inst Oswaldo Cruz. 2023 Oct 9;118:e230044. doi: 10.1590/0074-02760230044. eCollection 2023.ABSTRACTLipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell types in the...
Source: Memorias do Instituto Oswaldo Cruz - October 11, 2023 Category: Infectious Diseases Authors: Suelen Silva Gomes Dias Tamires Cunha-Fernandes Vinicius Cardoso Soares Cec ília Jg de Almeida Patricia T Bozza Source Type: research
Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Mem Inst Oswaldo Cruz. 2023 Oct 9;118:e230044. doi: 10.1590/0074-02760230044. eCollection 2023.ABSTRACTLipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell types in the...
Source: Memorias do Instituto Oswaldo Cruz - October 11, 2023 Category: Infectious Diseases Authors: Suelen Silva Gomes Dias Tamires Cunha-Fernandes Vinicius Cardoso Soares Cec ília Jg de Almeida Patricia T Bozza Source Type: research
Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Mem Inst Oswaldo Cruz. 2023 Oct 9;118:e230044. doi: 10.1590/0074-02760230044. eCollection 2023.ABSTRACTLipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell types in the...
Source: Memorias do Instituto Oswaldo Cruz - October 11, 2023 Category: Infectious Diseases Authors: Suelen Silva Gomes Dias Tamires Cunha-Fernandes Vinicius Cardoso Soares Cec ília Jg de Almeida Patricia T Bozza Source Type: research
Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Mem Inst Oswaldo Cruz. 2023 Oct 9;118:e230044. doi: 10.1590/0074-02760230044. eCollection 2023.ABSTRACTLipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell types in the...
Source: Memorias do Instituto Oswaldo Cruz - October 11, 2023 Category: Infectious Diseases Authors: Suelen Silva Gomes Dias Tamires Cunha-Fernandes Vinicius Cardoso Soares Cec ília Jg de Almeida Patricia T Bozza Source Type: research
First report of putative Leishmania RNA virus 2 (LRV2) in Leishmania infantum strains from canine and human visceral leishmaniasis cases in the southeast of Brazil
CONCLUSIONS: To the best of our knowledge, this is the first detection of LRV2 in the New World.PMID:37729273 | PMC:PMC10511063 | DOI:10.1590/0074-02760230071 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - September 20, 2023 Category: Infectious Diseases Authors: Felipe Dutra R êgo Eduardo S érgio da Silva Valeriana Valadares Lopes Rafael Gon çalves Teixeira-Neto Vin ícius Silva Belo Ant ônio Augusto Fonseca Júnior Diego Andrade Pereira Heber Paulino Pena M árcia Dalastra Laurenti Gabriela V Ara újo V âni Source Type: research
