Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
CONCLUSIONS: Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.PMID:37878831 | PMC:PMC10599233 | DOI:10.1590/0074-02760230116 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Bruna de Paula Fonseca Carlos Medicis Morel Source Type: research

Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells
CONCLUSION: Therefore, we believe that BZ has a beneficial role as it reduces inflammation in infected fat cells.PMID:37878830 | PMC:PMC10599316 | DOI:10.1590/0074-02760220295 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Leyllane Rafael Moreira Ana Carla Silva C íntia Nascimento da Costa Oliveira Claudeir Dias da Silva J únior Amanda Vasconcelos Nascimento Kamila K ássia Dos Santos Oliveira Ana Karine de Ara újo Soares Karina Lidianne Alc ântara Saraiva Milena de Pai Source Type: research

Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
CONCLUSIONS: Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.PMID:37878831 | PMC:PMC10599233 | DOI:10.1590/0074-02760230116 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Bruna de Paula Fonseca Carlos Medicis Morel Source Type: research

Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells
CONCLUSION: Therefore, we believe that BZ has a beneficial role as it reduces inflammation in infected fat cells.PMID:37878830 | PMC:PMC10599316 | DOI:10.1590/0074-02760220295 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Leyllane Rafael Moreira Ana Carla Silva C íntia Nascimento da Costa Oliveira Claudeir Dias da Silva J únior Amanda Vasconcelos Nascimento Kamila K ássia Dos Santos Oliveira Ana Karine de Ara újo Soares Karina Lidianne Alc ântara Saraiva Milena de Pai Source Type: research

Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
CONCLUSIONS: Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.PMID:37878831 | PMC:PMC10599233 | DOI:10.1590/0074-02760230116 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Bruna de Paula Fonseca Carlos Medicis Morel Source Type: research

Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells
CONCLUSION: Therefore, we believe that BZ has a beneficial role as it reduces inflammation in infected fat cells.PMID:37878830 | PMC:PMC10599316 | DOI:10.1590/0074-02760220295 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Leyllane Rafael Moreira Ana Carla Silva C íntia Nascimento da Costa Oliveira Claudeir Dias da Silva J únior Amanda Vasconcelos Nascimento Kamila K ássia Dos Santos Oliveira Ana Karine de Ara újo Soares Karina Lidianne Alc ântara Saraiva Milena de Pai Source Type: research

Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
CONCLUSIONS: Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.PMID:37878831 | PMC:PMC10599233 | DOI:10.1590/0074-02760230116 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Bruna de Paula Fonseca Carlos Medicis Morel Source Type: research

Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells
CONCLUSION: Therefore, we believe that BZ has a beneficial role as it reduces inflammation in infected fat cells.PMID:37878830 | PMC:PMC10599316 | DOI:10.1590/0074-02760220295 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Leyllane Rafael Moreira Ana Carla Silva C íntia Nascimento da Costa Oliveira Claudeir Dias da Silva J únior Amanda Vasconcelos Nascimento Kamila K ássia Dos Santos Oliveira Ana Karine de Ara újo Soares Karina Lidianne Alc ântara Saraiva Milena de Pai Source Type: research

Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
CONCLUSIONS: Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.PMID:37878831 | PMC:PMC10599233 | DOI:10.1590/0074-02760230116 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Bruna de Paula Fonseca Carlos Medicis Morel Source Type: research

Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells
CONCLUSION: Therefore, we believe that BZ has a beneficial role as it reduces inflammation in infected fat cells.PMID:37878830 | DOI:10.1590/0074-02760220295 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Leyllane Rafael Moreira Ana Carla Silva C íntia Nascimento da Costa Oliveira Claudeir Dias da Silva J únior Amanda Vasconcelos Nascimento Kamila K ássia Dos Santos Oliveira Ana Karine de Ara újo Soares Karina Lidianne Alc ântara Saraiva Milena de Pai Source Type: research

Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
CONCLUSIONS: Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.PMID:37878831 | DOI:10.1590/0074-02760230116 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 25, 2023 Category: Infectious Diseases Authors: Bruna de Paula Fonseca Carlos Medicis Morel Source Type: research

Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report
CONCLUSIONS: This case demonstrates that Long COVID-19 may develop even after mild disease due to SARS-CoV-2 in fully vaccinated and boosted individuals without comorbidities. Continued monitoring of new SARS-CoV-2 lineages and associated clinical outcomes is warranted. Measures to prevent infection should continue to be implemented including development of new vaccines and antivirals effective against novel variants.PMID:37851721 | PMC:PMC10581372 | DOI:10.1590/0074-02760230069 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Ot ávio Espíndola Paola C Resende Lusiele Guaraldo Guilherme Amaral Calvet Trevon L Fuller Stephanie Lema Suarez Penetra Heloisa Ferreira Pinto Santos Anielle Pina-Costa Michele Fernanda Borges da Silva Isabella Campos Vargas Moraes Fernando Medeiros Ji Source Type: research

Differences in responses to the intracellular macrophage environment between Mycobacterium bovis BCG vaccine strains Moreau and Pasteur
CONCLUSION: Overall, our results show that, compared to Pasteur, BCG Moreau has increased fitness and better endurance in the harsh intracellular environment, also regulating anti-microbial responses (lower IL-1b and MCP-1). These findings contribute to the understanding of the physiology of BCG Moreau and Pasteur in response to the intraphagosomal environment in a THP-1 macrophage model.PMID:37851722 | PMC:PMC10581373 | DOI:10.1590/0074-02760230070 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Paloma Rezende Corr êa Marcos Gustavo Araujo Schwarz Renata Monteiro Maia F átima Maria Figueroa Vergara Milton Oz ório Moraes Leila Mendon ça-Lima Source Type: research

Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report
CONCLUSIONS: This case demonstrates that Long COVID-19 may develop even after mild disease due to SARS-CoV-2 in fully vaccinated and boosted individuals without comorbidities. Continued monitoring of new SARS-CoV-2 lineages and associated clinical outcomes is warranted. Measures to prevent infection should continue to be implemented including development of new vaccines and antivirals effective against novel variants.PMID:37851721 | PMC:PMC10581372 | DOI:10.1590/0074-02760230069 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Ot ávio Espíndola Paola C Resende Lusiele Guaraldo Guilherme Amaral Calvet Trevon L Fuller Stephanie Lema Suarez Penetra Heloisa Ferreira Pinto Santos Anielle Pina-Costa Michele Fernanda Borges da Silva Isabella Campos Vargas Moraes Fernando Medeiros Ji Source Type: research

Differences in responses to the intracellular macrophage environment between Mycobacterium bovis BCG vaccine strains Moreau and Pasteur
CONCLUSION: Overall, our results show that, compared to Pasteur, BCG Moreau has increased fitness and better endurance in the harsh intracellular environment, also regulating anti-microbial responses (lower IL-1b and MCP-1). These findings contribute to the understanding of the physiology of BCG Moreau and Pasteur in response to the intraphagosomal environment in a THP-1 macrophage model.PMID:37851722 | PMC:PMC10581373 | DOI:10.1590/0074-02760230070 (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - October 18, 2023 Category: Infectious Diseases Authors: Paloma Rezende Corr êa Marcos Gustavo Araujo Schwarz Renata Monteiro Maia F átima Maria Figueroa Vergara Milton Oz ório Moraes Leila Mendon ça-Lima Source Type: research