Second heart field-specific expression of Nkx2-5 requires promoter proximal interaction with Srf
Publication date: Available online 22 May 2020Source: Mechanisms of DevelopmentAuthor(s): Christopher D. Clark, Kyu-Ho Lee (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 23, 2020 Category: Biology Source Type: research

Regulation of axial and head patterning during planarian regeneration by a commensal bacterium
Publication date: Available online 18 May 2020Source: Mechanisms of DevelopmentAuthor(s): Katherine Williams, Johanna Bischof, Frederick Lee, Kelsie Miller, Jennifer LaPalme, Benjamin Wolfe, Michael Levin (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 20, 2020 Category: Biology Source Type: research

A LCMS-based untargeted lipidomics analysis of cleft palate in mouse
Publication date: Available online 11 May 2020Source: Mechanisms of DevelopmentAuthor(s): Wancong Zhang, Hanxing Zhao, Jiasheng Chen, Xiaoping Zhong, Weiping Zeng, Bingna Zhang, Kai Qi, Zhonglei Li, Jianda Zhou, Lungang Shi, Zhihao He, Shijie Tang (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 12, 2020 Category: Biology Source Type: research

Long noncoding RNA XIST regulates osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting miR-9-5p
Publication date: Available online 8 May 2020Source: Mechanisms of DevelopmentAuthor(s): Chenying Zheng, Chunxiao Bai, Qi Sun, Fan Zhang, Qinsheng Yu, Xueqian Zhao, Shengqian Kang, Jinyu Li, Yusong Jia (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 8, 2020 Category: Biology Source Type: research

Postnatal development in the rat: Changes in Na+ flux, sodium pump molecular activity and membrane lipid composition
Publication date: Available online 7 May 2020Source: Mechanisms of DevelopmentAuthor(s): Paul L. Else (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 7, 2020 Category: Biology Source Type: research

MicroRNA-1-3p enhances osteoblast differentiation of MC3T3-E1 cells by interacting with hypoxia-inducible factor 1 α inhibitor (HIF1AN)
Publication date: Available online 6 May 2020Source: Mechanisms of DevelopmentAuthor(s): Long Zhou, Min Qiu, Lei Yang, Liyu Yang, Yiqi Zhang, Shuai Mu, Hanyi Song (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 6, 2020 Category: Biology Source Type: research

Binary fission in Trichoplax is orthogonal to the subsequent division plane
Publication date: Available online 6 May 2020Source: Mechanisms of DevelopmentAuthor(s): Jorge Zuccolotto-Arellano, Rodrigo Cuervo-González (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 6, 2020 Category: Biology Source Type: research

HYDIN loss-of-function inhibits GATA4 expression and enhances atrial septal defect risk
Publication date: Available online 3 May 2020Source: Mechanisms of DevelopmentAuthor(s): Yu Cao, Junying Guo, Jinping Zhang, Li Li, Hui Wang, Wenjun Ren, Lihong Jiang (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 5, 2020 Category: Biology Source Type: research

Outside Front Cover
Publication date: March 2020Source: Mechanisms of Development, Volume 161Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - March 29, 2020 Category: Biology Source Type: research

Rb family-independent activating E2F increases genome stability, promotes homologous recombination, and decreases non-homologous end joining
Publication date: Available online 23 March 2020Source: Mechanisms of DevelopmentAuthor(s): Xun Pei, Elbert Du, Zhentao Sheng, Wei Du (Source: Mechanisms of Development)
Source: Mechanisms of Development - March 24, 2020 Category: Biology Source Type: research

Outside Front Cover - Journal name, Cover image, Volume issue details, ISSN, Cover Date, Elsevier Logo and Society Logo if required
Publication date: March 2020Source: Mechanisms of Development, Volume 161Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - March 17, 2020 Category: Biology Source Type: research

Editorial Board
Publication date: March 2020Source: Mechanisms of Development, Volume 161Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - March 17, 2020 Category: Biology Source Type: research

Simulations of sea urchin early development delineate the role of oriented cell division in the morula-to-blastula transition
Publication date: Available online 9 March 2020Source: Mechanisms of DevelopmentAuthor(s): Lawrence Bodenstein (Source: Mechanisms of Development)
Source: Mechanisms of Development - March 10, 2020 Category: Biology Source Type: research

The gene regulatory control of sea urchin gastrulation
Publication date: Available online 28 February 2020Source: Mechanisms of DevelopmentAuthor(s): Charles A. Ettensohn (Source: Mechanisms of Development)
Source: Mechanisms of Development - February 29, 2020 Category: Biology Source Type: research

Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development
Publication date: Available online 13 February 2020Source: Mechanisms of DevelopmentAuthor(s): Yu-Hsiu Liu, Tz-Chi Lin, Sheng-Ping L. HwangAbstractPharyngeal arches are derived from all three germ layers and molecular interactions among the tissue types are required for proper development of subsequent pharyngeal cartilages; however, the mechanisms underlying this process are not fully described. Here we report that in zebrafish, Pax1a and Pax1b have overlapping and essential functions in pharyngeal pouch morphogenesis and subsequent ceratobranchial cartilage development. Both pax1a and pax1b are co-expressed in pharyngeal...
Source: Mechanisms of Development - February 13, 2020 Category: Biology Source Type: research

Transcriptome analysis of axolotl oropharyngeal explants during taste bud differentiation stages
Publication date: Available online 7 February 2020Source: Mechanisms of DevelopmentAuthor(s): Priya Kohli, Lauren Marazzi, Deborah EastmanAbstractThe Mexican salamander, Ambystoma mexicanum (Axolotl), is an excellent vertebrate model system to understand development and regeneration. Studies in axolotl embryos have provided important insights into taste bud development. Taste bud specification and determination occur in the oropharyngeal endoderm of axolotl embryos during gastrulation and neurulation, respectively, whereas taste bud innervation and taste cell differentiation occur later in development. Axolotl embryos are ...
Source: Mechanisms of Development - February 8, 2020 Category: Biology Source Type: research

Disconnect between the developing eye and craniofacial prominences in the avian embryo
Publication date: Available online 7 February 2020Source: Mechanisms of DevelopmentAuthor(s): Jamil Jomaa, Jessica Martínez-Vargas, Shadya Essaili, Nida Haider, John AbramyanAbstractIn the amniote embryo, the upper jaw and nasal cavities form through coordinated outgrowth and fusion of craniofacial prominences. Adjacent to the embryonic prominences are the developing eyes, which abut the maxillary and lateral nasal prominences. The embryos of extant sauropsids (birds and nonavian reptiles) develop particularly large eyes in comparison to mammals, leading researchers to propose that the developing eye may facilitate ...
Source: Mechanisms of Development - February 8, 2020 Category: Biology Source Type: research

Claudin-7b and Claudin-h are required for controlling cilia morphogenesis in the zebrafish kidney
Publication date: Available online 27 December 2019Source: Mechanisms of DevelopmentAuthor(s): Miaomiao Jin, Donglian Wang, Wenyan Xu, Hong Wang, Ying CaoAbstractClaudins are a family of proteins which are the most important components of the tight junctions. The location of Claudins on the renal tubule epithelial determines its paracellular transport characteristics, but whether Claudins have other functions in kidneys remains still unclear. Here, we showed that the transcripts encoding two Claudin family proteins, claudin-7b (cldn-7b) and claudin-h (cldn-h), were expressed in the transporting cells in the zebrafish prone...
Source: Mechanisms of Development - December 29, 2019 Category: Biology Source Type: research

Functional analysis of engrailed in Tribolium segmentation
Publication date: Available online 26 November 2019Source: Mechanisms of DevelopmentAuthor(s): Jinsung Lim, Chong Pyo ChoeAbstractThe segment-polarity gene engrailed is required for segmentation in the early Drosophila embryo. Loss of Engrailed function results in segmentation defects that vary in severity from pair-rule phenotypes to a lawn phenotype lacking in obvious of segmentation. During segmentation, Engrailed is expressed in stripes with a single segmental periodicity in Drosophila, which is conserved in all arthropods examined so far. To define segments, the segmental stripes of Engrailed induce the segmental stri...
Source: Mechanisms of Development - November 26, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: December 2019Source: Mechanisms of Development, Volume 160Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - November 26, 2019 Category: Biology Source Type: research

Regulation of Numb during planar cell polarity establishment in the Drosophila eye
Publication date: Available online 31 October 2019Source: Mechanisms of DevelopmentAuthor(s): Pedro M. Domingos, Andreas Jenny, Keon F. Combie, David del Alamo, Marek Mlodzik, Hermann Steller, Bertrand MollereauAbstractThe establishment of planar cell polarity (PCP) in the Drosophila eye requires correct specification of the R3/R4 pair of photoreceptor cells, determined by a Frizzled mediated signaling event that specifies R3 and induces Delta to activate Notch signaling in the neighboring cell, specifying it as R4. Here, we investigated the role of the Notch signaling negative regulator Numb in the specification of R3/R4 ...
Source: Mechanisms of Development - November 1, 2019 Category: Biology Source Type: research

Editorial “MOD”
Publication date: Available online 21 October 2019Source: Mechanisms of DevelopmentAuthor(s): Roberto Mayor (Source: Mechanisms of Development)
Source: Mechanisms of Development - October 22, 2019 Category: Biology Source Type: research

Initiation and early growth of the skull vault in zebrafish
Publication date: Available online 20 October 2019Source: Mechanisms of DevelopmentAuthor(s): Michelle Kanther, Alexandra Scalici, Azman Rashid, Kelly Miao, Ella Van Deventer, Shannon FisherAbstractThe zebrafish offers powerful advantages as a model system for examining the growth of the skull vault and the formation of cranial sutures. The zebrafish is well suited for large–scale genetic screens, available in large numbers, and continual advances in genetic engineering facilitate precise modeling of human genetic disorders. Most importantly, zebrafish are continuously accessible for imaging during critical periods o...
Source: Mechanisms of Development - October 22, 2019 Category: Biology Source Type: research

The discovery of the fundamental role of VEGF in the development of the vascular system
This article summarizes the fundamental contributions that have been made in the early days of angiogenesis research to define the involvement of VEGF/VEGFRs in the developing vasculature.Graphical abstract (Source: Mechanisms of Development)
Source: Mechanisms of Development - October 20, 2019 Category: Biology Source Type: research

In vivo assessment of gonad status, secondary sex characteristics and spawning in transparent Casper zebrafish
In this study, the effects of DES on reproduction were determined in a novel way by using transparent Casper zebrafish that allow direct visualization of gonad status over time. Changes in gonad status with DES treatment were correlated with effects on secondary sex characteristics (i.e., genital vent size and breeding tubercles) spawning and embryo production. The results suggest that the Casper zebrafish is a useful model for studying dynamics of reproductive events in vertebrate gonads in vivo and for determining effects of EDCs on zebrafish reproduction. (Source: Mechanisms of Development)
Source: Mechanisms of Development - October 19, 2019 Category: Biology Source Type: research

The Hedgehog receptor Patched1 regulates proliferation, neurogenesis, and axon guidance in the embryonic spinal cord
Publication date: Available online 18 October 2019Source: Mechanisms of DevelopmentAuthor(s): Angelo Iulianella, Danielle Stanton-TurcotteAbstractThe formation of the vertebrate nervous system depends on the complex interplay of morphogen signaling pathways and cell cycle progression to establish distinct cell fates. The Sonic hedgehog (Shh) signaling pathway is well understood to promote ventral cell fates in the developing spinal cord. A key regulator of Shh signaling is its receptor Patched1 (Ptch1). However, because the Ptch1 null mutation is lethal early in mouse embryogenesis, its role in controlling cell cycle progr...
Source: Mechanisms of Development - October 19, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: October 2019Source: Mechanisms of Development, Volume 159Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - September 21, 2019 Category: Biology Source Type: research

An in vitro model of region-specific rib formation in chick axial skeleton: Intercellular interaction between somite and lateral plate cells
Publication date: Available online 4 September 2019Source: Mechanisms of DevelopmentAuthor(s): Kaoru Matsutani, Koji Ikegami, Hirohiko AoyamaAbstractThe axial skeleton is divided into different regions based on its morphological features. In particular, in birds and mammals, ribs are present only in the thoracic region. The axial skeleton is derived from a series of somites. In the thoracic region of the axial skeleton, descendants of somites coherently penetrate into the somatic mesoderm to form ribs. In regions other than the thoracic, descendants of somites do not penetrate the somatic lateral plate mesoderm. We perform...
Source: Mechanisms of Development - September 5, 2019 Category: Biology Source Type: research

EGL-38/Pax coordinates development in the Caenhorhabditis elegans egg-laying system through EGF pathway dependent and independent functions
Publication date: Available online 6 August 2019Source: Mechanisms of DevelopmentAuthor(s): Allison M. Webb Chasser, Ryan W. Johnson, Helen M. ChamberlinAbstractPaired box (Pax) proteins function as regulators of coordinated development in organogenesis by controlling factors such as cell growth and differentiation necessary to organize multiple cell types into a single, cohesive organ. Previous work has suggested that Pax transcription factors may regulate diverse cell types through participation in inductive cell-to-cell signaling, which has not been well explored. Here we show that EGL-38, a Pax2/5/8 ortholog, coordinat...
Source: Mechanisms of Development - August 7, 2019 Category: Biology Source Type: research

Long-label-retaining mammary epithelial cells are created early in ductal development and distributed throughout the branching ducts
Publication date: Available online 20 July 2019Source: Mechanisms of DevelopmentAuthor(s): Lauren N. Ragle, Robert D. Bruno, Corinne A. Boulanger, Gilbert H. SmithAbstractLong-label retention has been used by many to prove Cairns' immortal strand hypothesis and to identify potential stem cells. Here, we describe two strategies using 5-ethynl-2′-deoxyuridine (EdU) to identify and understand the distribution of long-label-retaining mammary epithelial cells during formation of the mouse mammary ductal system. First, EdU was given upon two consecutive days per week during weeks 4 through 10 and analyzed for label retenti...
Source: Mechanisms of Development - July 21, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: August 2019Source: Mechanisms of Development, Volume 158Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - July 13, 2019 Category: Biology Source Type: research

Use of in vitro electroporation and slice culture for gene function analysis in the mouse embryonic spinal cord
In this study, we have demonstrated the expression of an exogenous gene on one side of the spinal cord by combining two methods—in vitro electroporation of embryonic mouse spinal cord and organ spinal cord slices culture. We took 12-day embryonic mice, injected the green fluorescent protein (pCAGGS-GFP) plasmid into the spinal cord cavity in vitro, and then electroporated. The spinal cord was cut into 300-μm slices using a vibratory microtome. After cultured for 48 h, GFP-positive neurons were clearly observed on one side of the spinal cord, indicating that the exogenous gene was successfully transferred. The ax...
Source: Mechanisms of Development - June 16, 2019 Category: Biology Source Type: research

Nicole Le Douarin and the use of quail-chick chimeras to study the developmental fate of neural crest and hematopoietic cells
This article summarizes the fundamental contribution of Nicole Le Douarin to the discovery and the application of this technique over the last 40 years. (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 24, 2019 Category: Biology Source Type: research

Single origin of the epithelium of the human middle ear
ConclusionDifferent morphological epithelial appearances throughout the tympanic and temporal bone cavities could be explained by different stages of epithelial differentiation rather than different embryologic origin and endodermal rupture does not seem to be a necessity for these cavities to form. (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 21, 2019 Category: Biology Source Type: research

The microRNA-306/abrupt regulatory axis controls wing and haltere growth in Drosophila
Publication date: Available online 18 May 2019Source: Mechanisms of DevelopmentAuthor(s): Carolina J. Simoes da Silva, Ismael Sospedra, Ricardo Aparicio, Ana BusturiaAbstractGrowth control relies on extrinsic and intrinsic mechanisms that regulate and coordinate the size and pattern of organisms. This control is crucial for a homeostatic development and healthy physiology. The gene networks acting in this process are large and complex: factors involved in growth control are also important in diverse biological processes and these networks include multiple regulators that interact and respond to intra- and extra-cellular in...
Source: Mechanisms of Development - May 19, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: June 2019Source: Mechanisms of Development, Volume 157Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - May 18, 2019 Category: Biology Source Type: research

The transcription factor Foxp1 regulates the differentiation and function of dendritic cells
In this study, we found that the expression of the transcription factor Foxp1 gradually increased during the maturation of DCs. Then, we constructed a recombinant adenovirus carrying Foxp1-interfering RNA (Ad-simFoxp1) and transfected murine bone marrow-derived DCs in vitro. DCs transfected with Ad-simFoxp1 exhibited markedly lower costimulatory molecules, and decreased cytokines. And Ad-simFoxp1 greatly inhibited mature DC-induced T cell responses. Moreover, in vivo infusion with Ad-simFoxp1-modified DCs significantly delayed the onset of experimental autoimmune encephalomyelitis (EAE). Therefore, adoptive transfection of...
Source: Mechanisms of Development - May 9, 2019 Category: Biology Source Type: research

High temperature limits on developmental canalization in the ascidian Ciona intestinalis
This study reveals a high temperature threshold, occurring over a 1–2 °C range, for normal embryonic development in C. intestinalis. Above that threshold the prevalence of morphological abnormalities increases significantly, beginning with cleavage and gastrula stages, and becoming more pronounced as embryogenesis proceeds. However, even in highly morphologically abnormal temperature disrupted (TD) embryos, muscle, endoderm, notochord, epidermis, and sensory pigment cells are recognizable, as evidenced by histochemical markers or morphology. On the other hand, morphogenesis of the notochord and other structures...
Source: Mechanisms of Development - April 25, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: April 2019Source: Mechanisms of Development, Volume 156Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - April 25, 2019 Category: Biology Source Type: research

Synchronization of Hes1 oscillations coordinates and refines condensation formation and patterning of the avian limb skeleton
Publication date: April 2019Source: Mechanisms of Development, Volume 156Author(s): Ramray Bhat, Tilmann Glimm, Marta Linde-Medina, Cheng Cui, Stuart A. NewmanAbstractThe tetrapod appendicular skeleton is initiated as spatially patterned mesenchymal condensations. The size and spacing of these condensations in avian limb buds are mediated by a reaction-diffusion-adhesion network consisting of galectins Gal-1A, Gal-8 and their cell surface receptors. In cell cultures, the appearance of condensations is synchronized across distances greater than the characteristic wavelength of their spatial pattern. We explored the possible...
Source: Mechanisms of Development - April 16, 2019 Category: Biology Source Type: research

Zebrafish otolith biomineralization requires polyketide synthase
This study will serve as a basis for investigating the role of eNOS signaling and Endothelin-1 signaling during otolith formation. (Source: Mechanisms of Development)
Source: Mechanisms of Development - April 8, 2019 Category: Biology Source Type: research

Prenatal catch-up growth: A study in avian embryos
Publication date: Available online 29 March 2019Source: Mechanisms of DevelopmentAuthor(s): Jacopo P. MortolaAbstractWhether the growth of embryos after a period of stunt becomes accelerated (Catch-Up Growth, CUGr), as it occurs postnatally, has rarely been examined experimentally in any class of animals. Here, hypoxia or cold of different degrees and durations caused growth retardation in chicken embryos during the first or second week of incubation. On average, on the day of removal of the growth-inhibition, the weight of the experimental groups was 73% (wet) and 61% (dry) of control embryos, while near end-incubation (e...
Source: Mechanisms of Development - March 30, 2019 Category: Biology Source Type: research

Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway
Publication date: Available online 20 March 2019Source: Mechanisms of DevelopmentAuthor(s): Leif R. Neitzel, Zachary T. Spencer, Anmada Nayak, Christopher S. Cselenyi, Hassina Benchabane, CheyAnne Q. Youngblood, Alya Zouaoui, Victoria Ng, Leah Stephens, Trevor Hann, James G. Patton, David Robbins, Yashi Ahmed, Ethan LeeAbstractIn a screen for human kinases that regulate Xenopus laevis embryogenesis, we identified Nagk and other components of the UDP-GlcNAc glycosylation salvage pathway as regulators of anteroposterior patterning and Wnt signaling. We find that the salvage pathway does not affect other major embryonic signa...
Source: Mechanisms of Development - March 21, 2019 Category: Biology Source Type: research

Synchronization of Hes1 oscillations coordinate and refine condensation formation and patterning of the avian limb skeleton
Publication date: Available online 10 March 2019Source: Mechanisms of DevelopmentAuthor(s): Ramray Bhat, Tilmann Glimm, Marta Linde-Medina, Cheng Cui, Stuart A. NewmanAbstractThe tetrapod appendicular skeleton is initiated as spatially patterned mesenchymal condensations. The size and spacing of these condensations in avian limb buds are mediated by a reaction-diffusion-adhesion network consisting of galectins Gal-1A, Gal-8 and their cell surface receptors. In cell cultures, the appearance of condensations is synchronized across distances greater than the characteristic wavelength of their spatial pattern. We explored the ...
Source: Mechanisms of Development - March 11, 2019 Category: Biology Source Type: research

Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development
This study reveals another role for hemodynamic force in regulating blood vessel development of the mouse, and opens up a new model to begin elucidating mechanotransduction pathways regulating vascular maturation.Graphical abstractIn normal flow embryos, vascular maturation occurs by the recruitment of vSMCs in the mesoderm to blood vessels exposed to high flow. This is followed by the attachment of the vSMCs to the high-flow vessels. In reduced-flow embryos, the vessels are exposed to lower flow, which minimizes the amount of recruited vSMCs towards any particular vessel. (Source: Mechanisms of Development)
Source: Mechanisms of Development - February 22, 2019 Category: Biology Source Type: research

Detecting coevolution of positively selected in turtles sperm-egg fusion proteins
Publication date: Available online 18 February 2019Source: Mechanisms of DevelopmentAuthor(s): Jingxiu Dong, Hui Jiang, Lei Xiong, Jiawei Zan, Jianjun Liu, Mengli Yang, Kai Zheng, Ziming Wang, Liuwang NieAbstractPhysically interacting sperm-egg proteins have been identified using gene-modified animals in some mammal species. Three proteins are essential for sperm-egg binding: Izumo1 on the sperm surface, and JUNO and CD9 on the egg surface. Most proteins linked to reproductive function evolve rapidly among species by positive selection, and have correlated evolutionary rates to compensate for changes on both the sperm and ...
Source: Mechanisms of Development - February 18, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: February 2019Source: Mechanisms of Development, Volume 155Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - January 31, 2019 Category: Biology Source Type: research

Xenopus slc7a5 is essential for notochord function and eye development
In this study, expression and function of slc7a5 were evaluated in Xenopus laevis embryos that develop without a placenta. Expression of slc7a5 was detected in the notochord and in the eye and it was not co-localized with slc3a2, which helps slc7a5 to localize at the plasma membrane, before the late neurula stage. Loss-of-function experiment with a morpholino antisense oligonucleotide led to defect of neural and non-neural patterning, inhibition of primary neurogenesis, and disruption of eye development. Disruption of neural development and primary neurogenesis was likely due to impaired notochord development as sonic hedg...
Source: Mechanisms of Development - January 7, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: December 2018Source: Mechanisms of Development, Volume 154Author(s): (Source: Mechanisms of Development)
Source: Mechanisms of Development - December 8, 2018 Category: Biology Source Type: research

MoD Special issue on “Developmental Biology in Latin America”
Publication date: December 2018Source: Mechanisms of Development, Volume 154Author(s): Juan R. Riesgo-Escovar, Roberto Mayor, Pablo Wappner, Irene Yan (Source: Mechanisms of Development)
Source: Mechanisms of Development - December 8, 2018 Category: Biology Source Type: research