The Importance of Estimating Excess Deaths Regionally During the COVID-19 Pandemic
National or statewide estimates of excess deaths have limited value to understanding the impact of the COVID-19 pandemic regionally. We assessed excess deaths in a 9-county geographically defined population that had low rates of COVID-19 and widescale availability of testing early in the pandemic, well-annotated clinical data, and coverage by 2 medical examiner ’s offices. We compared mortality rates (MRs) per 100,000 person-years in 2020 and 2021 with those in the 2019 reference period and MR ratios (MRRs). (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Suzette J. Bielinski, Sheila M. Manemann, Guilherme S. Lopes, Ruoxiang Jiang, Susan A. Weston, R. Ross Reichard, Aaron D. Norman, Celine M. Vachon, Paul Y. Takahashi, Mandeep Singh, Nicholas B. Larson, V éronique L. Roger, Jennifer L. St. Sauver Tags: Brief report Source Type: research

Management of Patients With Kidney Disease Undergoing Bariatric Surgery
Bariatric surgery is increasingly recognized as a safe and effective treatment for obesity in patients with chronic kidney disease (CKD), including stages 4, 5, and 5D (on dialysis). Among the available surgical methods, sleeve gastrectomy (SG) is the most commonly performed weight loss procedure and is mainly done to facilitate kidney transplantation (KT). However, many KT candidates treated with SG remain on the transplant waiting list for months to years, with some never receiving a transplant. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Aleksandra Kukla, Yogish C. Kudva, Pavel Navratil, Sukhdeep S. Sahi, Roberto P. Benzo, David C. Fipps, Avery E. Erickson, Rachael R. Majorowicz, Matthew M. Clark, Carrie A. Schinstock, Pankaj Shah, Meera Shah, Tayyab S. Diwan Tags: Special article Source Type: research

Aortitis Increases Risk of Relapse and Vascular Events in Takayasu Arteritis
Takayasu arteritis (TA) is a rare panarteritis disease of large vessels including the aorta and its main branches; with an incidence rate of 1.11 per million person-years, it affects mostly women between 20 and 30 years.1 Long-term prognosis is marked by a high relapse rate with need of multiple-line immunosuppressive agents and vascular morbidity due to arterial lesions leading to cardiovascular complications or interventions. Some risk factors have been identified to be associated with higher relapse rate, such as the presence at diagnosis of elevated inflammatory biomarkers, carotidynia, and male sex. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Alexis F. Gu édon, Romain Collot, Christian Agard, Alizée Raimbeau, Antoine Bénichou, Jérôme Connault, Arsène Mekinian, Olivier Espitia Tags: Research letter Source Type: research

Preventing and Responding to Physician Suicide
When Buffalo Bills football player Damar Hamlin had cardiac arrest during the team ’s game on January 2, 2023, the emergency medical response and the decision to cancel the game showed crisis preparedness and sensitivity to the athletes’ emotions.1 Like sports teams, health care teams must be prepared to respond to unexpected critical events. Injury and even untimely death are risks incurred by virtually any worker or professional, including physicians, and one well-documented and concerning risk for physicians is suicide. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Terry L. Hunt, W. Michael Hooten Tags: Perspective and controversy Source Type: research

Older Adults ’ Perceptions of Their Risk and Its Correlation With Coronary Atherosclerosis Burden
Self-rated health (SRH) is an individual ’s self-evaluation of well-being, as influenced by social and biological factors, that correlates with cardiovascular risk factors, cardiovascular disease (CVD), and cardiac and all-cause mortality.1,2 Coronary artery calcium (CAC) scoring, which quantifies the burden of calcified coronary atheros clerosis by cardiac computed tomography, serves as a more exact and personalized measure of CVD risk than traditional 10-year atherosclerotic CVD risk scores by capturing lifetime exposure to traditional risk factors, additional risk enhancers, and genetic predisposition. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Garshasb Soroosh, Zeina Dardari, Candace Howard-Claudio, Pamela Lutsey, Kunihiro Matsushita, Michael Blaha Tags: Research letter Source Type: research

Children ’s Author and Cartoonist Dr. Seuss: Not That Kind of Doctor, But a Medical School Bears His Name
Theodor “Ted” Seuss Geisel was born in Springfield, Massachusetts, on March 2, 1904. His paternal grandfather, Theodor, was a jeweler who emigrated from Germany to the United States in 1867 and bought a brewery. His father managed the brewery until Prohibition banned alcohol sales in 1920, then became a park supervisor for the city of Springfield. One of the city’s parks included a zoo, and young Ted, who showed skill at drawing early in life, frequently sketched the animals. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: David P. Steensma Tags: Stamp vignette on medical science Source Type: research

Floating World by Charles Munch
Art is integrated into the Mayo Clinic environment. Since the original Mayo Clinic Building was finished in 1914, many pieces have been donated or commissioned for patients and staff to enjoy. Each issue of Mayo Clinic Proceedings features a work of art (as interpreted by the author) that is displayed in a building or on the grounds of Mayo Clinic campuses. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Margaret R. Wentz Tags: Art at mayo clinic Source Type: research

Heart Failure and Hypertrophic Cardiomyopathy —Looking Back on Decades of Remarkable Progress
Hypertrophic cardiomyopathy (HCM) is a complex genetic disease that results in pathologic left ventricular hypertrophy with associated heart failure. From its earliest descriptions as “functional” aortic stenosis due to severe ventricular septal hypertrophy,1 there has been tremendous advance in our biologic understanding of HCM. We now understand that clinical HCM can manifest with symptomatic heart failure in a highly diverse way ranging from dynamic left ventricular outflo w tract obstruction1 to nonobstructive HCM with restrictive cardiomyopathy2 or rarely with ventricular arrhythmia and sudden death. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Yogesh N.V. Reddy Tags: Editorial Source Type: research

Insights on Adrenal Hemorrhage
Adrenal hemorrhage refers to bleeding within the capsule of 1 or both adrenal glands. It is perceived as an uncommon clinical entity that is generally poorly understood. It can be encountered in the setting of abdominal trauma or be atraumatic in the presence of predisposing conditions.1 Adrenal hemorrhage is likely to be underrecognized as no clinical features or blood tests can immediately alert to the diagnosis. It is unknown when clinicians should consider adrenal hemorrhage as a relevant contributing factor to illness because of a limited understanding of the full spectrum of adrenal hemorrhage and its predisposing co...
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Yasir S. Elhassan Tags: Editorial Source Type: research

In the Limelight: March 2024
This month ’s feature highlights three articles that appear in the current issue of Mayo Clinic Proceedings. These articles are also featured on the Mayo Clinic Proceedings’ YouTube Channel (https://youtu.be/lzlTn_R_Etw). (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Karl A. Nath Tags: In the limelight Source Type: research

Editorial Board
(Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Source Type: research

Table of Contents
(Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Source Type: research

General Information
(Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Source Type: research

Highlights From the Current Issue – Audiovisual Summary
Karl A. Nath, MBChB, Editor-in-Chief of Mayo Clinic Proceedings, discusses the Editor ’s Choice and Highlights articles appearing in the March 2024 issue. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 1, 2024 Category: Internal Medicine Authors: Karl A. Nath Tags: Issue summary Source Type: research

Degree of Risk Factor Control and Incident Cardiovascular Diseases in Patients With Hypertension
To investigate whether joint risk factor control could reduce the excess risk of cardiovascular disease (CVD) in patients with hypertension. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - February 6, 2024 Category: Internal Medicine Authors: Minghao Kou, Xuan Wang, Hao Ma, Xiang Li, Yoriko Heianza, Lu Qi Tags: Original article Source Type: research