Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 9;364:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods,...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

Evidence of the cooperative response of Blattella germanica gut microbiota to antibiotic treatment
Math Biosci. 2023 Aug 8:109057. doi: 10.1016/j.mbs.2023.109057. Online ahead of print.ABSTRACTGut microbiota plays a key role in host health under normal conditions. However, bacterial composition can be altered by external factors such as antibiotic (AB) intake. While there are many descriptive publications about the effects of AB on gut microbiota composition after treatment, the dynamics and interactions among the bacterial taxa are still poorly understood. In this work, we performed a longitudinal study of gut microbiome dynamics in B. germanica treated with kanamycin. The AB was supplied in three separate periods, giv...
Source: Mathematical Biosciences - August 10, 2023 Category: Statistics Authors: Irene Creus-Mart í Jes ús Marín-Miret Andr és Moya Francisco J Santonja Source Type: research

A topological data analysis study on murine pulmonary arterial trees with pulmonary hypertension
This study analyzes the change in pulmonary arterial morphometry in the presence of HPH using novel methods from topological data analysis (TDA). We employ persistent homology to quantify arterial morphometry for control and HPH mice characterizing normalized arterial trees extracted from micro-computed tomography (micro-CT) images. We normalize generated trees using three pruning algorithms before comparing the topology of control and HPH trees. This proof-of-concept study shows that the pruning method affects the spatial tree statistics and complexity. We find that HPH trees are stiffer than control trees but have more b...
Source: Mathematical Biosciences - August 7, 2023 Category: Statistics Authors: Megan Miller Natalie Johnston Ian Livengood Miya Spinelli Radmila Sazdanovic Mette S Olufsen Source Type: research

A topological data analysis study on murine pulmonary arterial trees with pulmonary hypertension
This study analyzes the change in pulmonary arterial morphometry in the presence of HPH using novel methods from topological data analysis (TDA). We employ persistent homology to quantify arterial morphometry for control and HPH mice characterizing normalized arterial trees extracted from micro-computed tomography (micro-CT) images. We normalize generated trees using three pruning algorithms before comparing the topology of control and HPH trees. This proof-of-concept study shows that the pruning method affects the spatial tree statistics and complexity. We find that HPH trees are stiffer than control trees but have more b...
Source: Mathematical Biosciences - August 7, 2023 Category: Statistics Authors: Megan Miller Natalie Johnston Ian Livengood Miya Spinelli Radmila Sazdanovic Mette S Olufsen Source Type: research

A topological data analysis study on murine pulmonary arterial trees with pulmonary hypertension
This study analyzes the change in pulmonary arterial morphometry in the presence of HPH using novel methods from topological data analysis (TDA). We employ persistent homology to quantify arterial morphometry for control and HPH mice characterizing normalized arterial trees extracted from micro-computed tomography (micro-CT) images. We normalize generated trees using three pruning algorithms before comparing the topology of control and HPH trees. This proof-of-concept study shows that the pruning method affects the spatial tree statistics and complexity. We find that HPH trees are stiffer than control trees but have more b...
Source: Mathematical Biosciences - August 7, 2023 Category: Statistics Authors: Megan Miller Natalie Johnston Ian Livengood Miya Spinelli Radmila Sazdanovic Mette S Olufsen Source Type: research

A two-galectin network establishes mesenchymal condensation phenotype in limb development
Math Biosci. 2023 Aug 4:109054. doi: 10.1016/j.mbs.2023.109054. Online ahead of print.ABSTRACTPrevious work showed that Gal-8 and Gal-1A, two proteins belonging to the galactoside-binding galectin family, are the earliest determinants of the patterning of the skeletal elements of embryonic chicken limbs, and further, that their experimentally determined interactions in the embryonic limb bud can be interpreted via a reaction-diffusion-adhesion (2GL: two galectin plus ligands) model. Here, we use an ordinary differential equation-based approach to analyze the intrinsic switching modality of the 2GL network and characterize ...
Source: Mathematical Biosciences - August 6, 2023 Category: Statistics Authors: T Glimm B Ka źmierczak S A Newman R Bhat Source Type: research

A two-galectin network establishes mesenchymal condensation phenotype in limb development
Math Biosci. 2023 Aug 4:109054. doi: 10.1016/j.mbs.2023.109054. Online ahead of print.ABSTRACTPrevious work showed that Gal-8 and Gal-1A, two proteins belonging to the galactoside-binding galectin family, are the earliest determinants of the patterning of the skeletal elements of embryonic chicken limbs, and further, that their experimentally determined interactions in the embryonic limb bud can be interpreted via a reaction-diffusion-adhesion (2GL: two galectin plus ligands) model. Here, we use an ordinary differential equation-based approach to analyze the intrinsic switching modality of the 2GL network and characterize ...
Source: Mathematical Biosciences - August 6, 2023 Category: Statistics Authors: T Glimm B Ka źmierczak S A Newman R Bhat Source Type: research

Stationary status of discrete and continuous age-structured population models
This article argues how the partition theorem-based approach provides more up-to-date and timely measures to find the status of the population stationarity of a country better than the NRR-based approach. We question the timeliness of the value of NRR in deciding the stationary process of the country. We prove associated theorems on discrete and continuous age distributions and derive measurable functional properties. The partitioning metric captures the underlying age structure dynamic of populations at or near stationarity. As the population growth rates for an ever-increasing number of countries trend towards replacemen...
Source: Mathematical Biosciences - August 4, 2023 Category: Statistics Authors: Arni S R Srinivasa Rao James R Carey Source Type: research

Stationary status of discrete and continuous age-structured population models
This article argues how the partition theorem-based approach provides more up-to-date and timely measures to find the status of the population stationarity of a country better than the NRR-based approach. We question the timeliness of the value of NRR in deciding the stationary process of the country. We prove associated theorems on discrete and continuous age distributions and derive measurable functional properties. The partitioning metric captures the underlying age structure dynamic of populations at or near stationarity. As the population growth rates for an ever-increasing number of countries trend towards replacemen...
Source: Mathematical Biosciences - August 4, 2023 Category: Statistics Authors: Arni S R Srinivasa Rao James R Carey Source Type: research