Reference intervals for CTX and P1NP in a multi-ethnic Malaysian cohort
CONCLUSION: The reference intervals for plasma CTX and serum PINP for older Malaysian men and post-menopausal women are somewhat different to other published studies from the region, emphasising the importance of establishing specific reference intervals for each population.PMID:38155380 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: R Z Tan S C Thambiah T P Loh S Vasikaran S S Yeap Source Type: research
Species-specific PCR primers for simultaneous detection of Aspergillus fumigatus, Aspergillus terreus, Candida albicans and Candida glabrata in invasive fungal infections
In conclusion, this quadruplex PCR assay is specific, rapid and reliable to detect A. fumigatus, A. terreus, C. albicans and C. glabrata simultaneously.PMID:38155381 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: Y K M Ismadi S Mohamad A Harun Source Type: research
Clinicopathological characteristics of myelodysplastic syndromes with del(5q) in Taiwan
CONCLUSION: The bone marrow morphology, clinical features, and prognosis of Taiwanese MDS patients with del(5q) were different from those associated with MDS with isolated del(5q) as defined in the current WHO classification. Researchers should compare different geographic regions and racial populations to determine whether geographic and racial differences exist with respect to MDS with del(5q).PMID:38155382 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: C F Yang C Y Hsu L T Hsiao S W Chen S S Chuang Source Type: research
Antifungal susceptibility profile and biofilm-producing capability of Candida tropicalis isolates in a tertiary medical centre
CONCLUSION: The C. tropicalis isolates from our centre were resistant only to triazole agents, with the highest resistance rate being recorded for fluconazole and the lowest for posaconazole. While this is not by itself alarming, the fact that our isolates were prolific biofilm producers means that even azole-susceptible isolates can be paradoxically refractory to antifungal therapy.PMID:38155383 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S D Navarathinam H M Neoh T L Tan A A Wahab M N Mohd Nizam Tzar C H Ding Source Type: research
Placenta microRNA profile of patient with Obstetric Antiphospholipid Syndrome
In this study, we aimed to profile miRNA expressions from placenta tissue of patients with APS. Differentially expressed miRNAs were determined for its targeted genes and pathways. Agilent microarray platform was used to measure placental microRNA expressions between normal placental tissue and those obtained from patients with APS. Differentially expressed miRNAs were detected using GeneSpring GX software 14.2 and sequences were mapped using TargetScan software to generate the predicted target genes. Pathway analysis for the genes was then performed on PANTHER and REACTOME software. Selected miRNAs and their associated ge...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: M A Mohamad A W Ahmad Asnawi M S Suhiman J Sathar A R Hayati N S Abdul Rahim M A Masri N Abdul Hamid S Nurul Farihah N Mohamad Nor M M Nur Fariha Source Type: research
Epidemiology of neonatal pneumothorax developed spontaneously and during respiratory supports in neonatal intensive care units
CONCLUSIONS: The most common type of pneumothorax was spontaneous in-onset. Neonates on HFV had the highest and those on nCPAPt the lowest rate of pneumothorax. Improving training of resuscitation techniques at birth and strategies of use of invasive modes of respiratory support may reduce incidences of all types of pneumothorax.PMID:38155385 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: N Y Boo E L Lee Ang None The Malaysian National Neonatal Registry Source Type: research
Suction rectal biopsy (SRB) in Hirschsprung's Disease: Is a single macroscopically adequate sample sufficient?
In conclusion, single sample SRBs can be adequately diagnostic and cost-effective in low-resource settings, providing valuable insights for healthcare facilities in Malaysia and other developing countries. The use of adjunctive techniques such as calretinin staining may improve diagnostic accuracy while maintaining cost-effectiveness. Further prospective studies with larger sample sizes are needed to validate these findings.PMID:38155386 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: P K Bal S A Nah W M R Wan Mohamad Noor M T Md Nor S Singaravel W S Tan Y W Tan A Sanmugam Source Type: research
CD47 and CD36 expressions in the placenta of mothers with chorioamnionitis
DISCUSSION: Our study showed CD47 was expressed in the neutrophils and it was associated with poorer perinatal outcomes and it may have a role in the pathogenesis of chorioamnionitis.PMID:38155387 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: B S Hanim R A Rahim M F Mohd Salleh H Zakaria N Abd Shukor Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
The circulating cells with blast-like morphology in transient abnormal myelopoiesis of Down syndrome are unique and deserve a specific name: Would the term "megakaryogones" serve this purpose?
Malays J Pathol. 2023 Dec;45(3):479-480.ABSTRACTNo abstract available.PMID:38155389 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S B Kahwash K Nicol Source Type: research
Abstracts of the International Congress of Pathology & amp; Laboratory Medicine 2023: Precision Medicine: Revolutionizing Pathology in Genomic Era, organised by the College of Pathologists, Academy of Medicine of Malaysia and at World Trade Centre Kuala Lumpur on 20-22 September 2023
Malays J Pathol. 2023 Dec;45(3):481-566.ABSTRACTNo abstract available.PMID:38155390 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Source Type: research
Abstracts of the National Pathology Conference 2023 by Perak Pathology Services held at Hotel Casuarina Ipoh Perak on 2nd and 3rd August 2023
Malays J Pathol. 2023 Dec;45(3):567-591.ABSTRACTNo abstract available.PMID:38155391 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Source Type: research
MJP going green
Malays J Pathol. 2023 Dec;45(3):315.ABSTRACTNo abstract available.PMID:38155374 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: G C Tan S K Cheong Source Type: research
Biomarkers for colorectal cancer chemotherapy: Recent updates and future perspective
Malays J Pathol. 2023 Dec;45(3):317-331.ABSTRACTDuring the last few decades, the treatment options available for patients with metastatic colorectal cancer (mCRC) have undergone continuous improvements, transitioning from conventional chemotherapy to targeted therapy. These therapeutic innovations have led to significant improvements in patient clinical outcomes. However, there remains a need to improve the outcome for many CRC patients. Chemotherapy remains a cornerstone of CRC treatment, but the wide variability in tumour response and adverse reactions to chemotherapy poses a challenge to cancer treatment management. As ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: P Y Lee F S Md Azhan T Y Low Source Type: research
Urolithiasis: History, epidemiology, aetiologic factors and management
Malays J Pathol. 2023 Dec;45(3):333-352.ABSTRACTUrolithiasis is defined as a disease diagnosed by the presence of one or more stones in the urinary tract. It is one of the oldest and most widespread diseases known to man, their discovery and characterisation chronology began with the civilisation's history. This pathology has a multifactorial aetiology, very frequent worldwide with geographic and racial variation, their prevalence is increasing in lockstep with socioeconomic development. In fact, this disorder affects between 2 and 20% of the population, with an approximate recurrence rate of 30% to 50% in 5 years. Further...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: R Kachkoul G B Touimi G El Mouhri R El Habbani M Mohim A Lahrichi Source Type: research
