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I was very impressed and somewhat surprised by Drs Minerva Becker and Valentina Garibotto ’s candor regarding the evolution of PET-MR imaging in their preface. Instead of touting PET/MR imaging as a “wonder modality,” they give an elegant and accurate description of the history of PET-MR imaging using the analogy of the Gartner “Hype Cycle.” The initial excitement of high expec tations was followed by the realities of trying to demonstrate the tangible benefits of combining two important modalities into an hybrid modality to justify the high costs to hospital administrators, payors, and patients. (Source: Magneti...
Source: Magnetic Resonance Imaging Clinics of North America - August 21, 2023 Category: Radiology Authors: Suresh K. Mukherji, Lynne Steinbach Tags: Foreword Source Type: research

PET/MR Imaging in Clinical Practice: After Expectations and (Some) Disillusion, a Slope of Enlightenment
Like many other technical innovations, PET/MR hybrid imaging has followed Gartner ’s hype cycle theory that the innovation trigger leads to a peak of inflated expectations, followed by a dip of disillusionment, and finally, a slope of enlightenment leading to a plateau of productivity. Since its introduction in the clinical field in 2010, the method has raised very high expecta tions across almost all clinical applications. The previous issue of the Magnetic Resonance Imaging Clinics of North America about this topic published in 2017 was still influenced by the initial enthusiasm. (Source: Magnetic Resonance Imaging Cli...
Source: Magnetic Resonance Imaging Clinics of North America - August 20, 2023 Category: Radiology Authors: Minerva Becker, Valentina Garibotto Tags: Preface Source Type: research

Update on Positron Emission Tomography/Magnetic Resonance Imaging
Hybrid PET/MRI is highly valuable, having made significant strides in overcoming technical challenges and offering unique advantages such as reduced radiation, precise data coregistration, and motion correction. Growing evidence highlights the value of PET/MRI in broad clinical aspects, including inflammatory and oncological imaging in adults, pregnant women, and pediatrics, potentially surpassing PET/CT. This newly integrated solution may be preferred over PET/CT in many clinical conditions. However, further technological advancements are required to facilitate its broader adoption as a routine diagnostic modality. (Sourc...
Source: Magnetic Resonance Imaging Clinics of North America - August 14, 2023 Category: Radiology Authors: Paniz Sabeghi, Sanaz Katal, Michelle Chen, Farzaneh Taravat, Thomas J. Werner, Babak Saboury, Ali Gholamrezanezhad, Abass Alavi Source Type: research

Recent Advances in Positron Emission Tomography/Magnetic Resonance Imaging Technology
More than a decade has passed since the clinical deployment of the first commercial whole-body hybrid PET/MR scanner in the clinic. The major advantages and limitations of this technology have been investigated from technical and medical perspectives. Despite the remarkable advantages associated with hybrid PET/MR imaging, such as reduced radiation dose and fully simultaneous functional and structural imaging, this technology faced major challenges in terms of mutual interference between MRI and PET components, in addition to the complexity of achieving quantitative imaging owing to the intricate MRI-guided attenuation cor...
Source: Magnetic Resonance Imaging Clinics of North America - August 8, 2023 Category: Radiology Authors: Hossein Arabi, Habib Zaidi Source Type: research

Clinical Value of Hybrid PET/MR Imaging
Hybrid PET/MR imaging offers a unique opportunity to acquire MR imaging and PET information during a single imaging session. PET/MR imaging has numerous advantages, including enhanced diagnostic accuracy, improved disease characterization, and better treatment planning and monitoring. It enables the immediate integration of anatomic, functional, and metabolic imaging information, allowing for personalized characterization and monitoring of neurologic diseases. This review presents recent advances in PET/MR imaging and highlights advantages in clinical practice for neuro-oncology, epilepsy, and neurodegenerative disorders. ...
Source: Magnetic Resonance Imaging Clinics of North America - August 8, 2023 Category: Radiology Authors: Aur élie Kas, Laura Rozenblum, Nadya Pyatigorskaya Source Type: research

The Clinical Added Value of Breast Cancer Imaging Using Hybrid PET/MR Imaging
Dedicated MR imaging is highly performant for the evaluation of the primary lesion and should regularly be added to whole-body PET/MR imaging for the initial staging. PET/MR imaging is highly sensitive for the detection of nodal involvement and could be combined with the high specificity of axillary second look ultrasound for the confirmation of the N staging. For M staging, with the exception of lung lesions, PET/MR imaging is superior to PET/computed tomography, at half the radiation dose. The predictive value of multiparametric imaging with PET/MR imaging holds promise to improve through radiomics and artificial intelli...
Source: Magnetic Resonance Imaging Clinics of North America - August 7, 2023 Category: Radiology Authors: Ismini C. Mainta, Ilektra Sfakianaki, Isaac Shiri, Diomidis Botsikas, Valentina Garibotto Source Type: research

Metabolic Imaging for Radiation Therapy Treatment Planning
The use of hybrid PET/MR imaging for radiotherapy treatment planning has the potential to reduce tumor and organ displacements caused by different scan times and setup changes. Although with mixed results mainly due to single-center studies with small sample size, PET/MR imaging could provide better target delineation, especially by reducing coregistration discrepancies on computed tomography simulation scan and offering better soft tissue contrast. The main limitation to drive stronger conclusions is due to the relatively low availability of hybrid PET/MR imaging systems, mainly limited to large academic centers. (Source:...
Source: Magnetic Resonance Imaging Clinics of North America - August 2, 2023 Category: Radiology Authors: Letizia Deantonio, Francesco Castronovo, Gaetano Paone, Giorgio Treglia, Thomas Zilli Source Type: research

Systematic Review and Metanalysis on the Role of Prostate-Specific Membrane Antigen Positron Emission Tomography/Magnetic Resonance Imaging for Intraprostatic Tumour Assessment
The present systematic review and meta-analysis are focused on the diagnostic accuracy of PSMA PET/MRI in primary prostate cancer assessment. A literature search was conducted on the PubMed database using the terms “PSMA” AND “prostate cancer” or “prostate” AND “PET/MRI” or “PET MRI” or “PET-MRI” or “PET-MR” AND “primary” or “staging.” Ten articles were eligible for analysis after applying the exclusion criteria. PET/MRI showed better diagnostic accuracy in detecting primary PCa compared to multiparametric (mp) MRI and PET alone. The pooled sensitivity and specificity of 68Ga-PSMA PET/MR...
Source: Magnetic Resonance Imaging Clinics of North America - August 2, 2023 Category: Radiology Authors: Paola Mapelli, Samuele Ghezzo, Alessandro Spataro, Carolina Bezzi, Ana Maria Samanes Gajate, Arturo Chiti, Maria Picchio Source Type: research

Abdominal Positron Emission Tomography/Magnetic Resonance Imaging
Hybrid positron emission tomography (PET)/magnetic resonance imaging (MRI) is highly suited for abdominal pathologies. A precise co-registration of anatomic and metabolic data is possible thanks to the simultaneous acquisition, leading to accurate imaging. The literature shows that PET/MRI is at least as good as PET/CT and even superior for some indications, such as primary hepatic tumors, distant metastasis evaluation, and inflammatory bowel disease. PET/MRI allows whole-body staging in a single session, improving health care efficiency and patient comfort. (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - July 31, 2023 Category: Radiology Authors: Álvaro Badenes Romero, Felipe S. Furtado, Madaleine Sertic, Reece J. Goiffon, Umar Mahmood, Onofrio A. Catalano Source Type: research

Pediatric Imaging Using PET/MR Imaging
PET/MR imaging is a one-stop shop technique for pediatric diseases allowing not only an accurate clinical assessment of tumors at staging and restaging but also the diagnosis of neurologic, inflammatory, and infectious diseases in complex cases. Moreover, applying PET kinetic analyses and sequences such as diffusion-weighted imaging as well as quantitative analysis investigating the relationship between disease metabolic activity and cellularity can be applied. Complex radiomics analysis can also be performed. (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - July 28, 2023 Category: Radiology Authors: Chiara Giraudo, Silvia Carraro, Pietro Zucchetta, Diego Cecchin Source Type: research

Four-Dimensional Flow MR Imaging
4D Flow MRI is an advanced imaging technique for comprehensive non-invasive assessment of the cardiovascular system. The capture of the blood velocity vector field throughout the cardiac cycle enables measures of flow, pulse wave velocity, kinetic energy, wall shear stress, and more. Advances in hardware, MRI data acquisition and reconstruction methodology allow for clinically feasible scan times. The availability of 4D Flow analysis packages allows for more widespread use in research and the clinic and will facilitate much needed multi-center, multi-vendor studies in order to establish consistency across scanner platforms...
Source: Magnetic Resonance Imaging Clinics of North America - July 5, 2023 Category: Radiology Authors: Oliver Wieben, Grant S. Roberts, Philip A. Corrado, Kevin M. Johnson, Alejandro Rold án-Alzate Source Type: research

MR Angiography of Pulmonary Vasculature
Pulmonary MR angiography (MRA) is a useful alternative to computed tomographic angiography (CTA) for the study of the pulmonary vasculature. For pulmonary hypertension and partial anomalous pulmonary venous return, a cardiac MR imaging and the pulmonary MRA are useful for flow quantification and planning treatment. For the diagnosis of pulmonary embolism (PE), MRA-PE has been shown to have non-inferior outcomes at 6  months when compared with CTA-PE. Over the last 15 years, pulmonary MRA has become a routine and reliable examination for the workup of pulmonary hypertension and the primary diagnosis of PE at the Universit...
Source: Magnetic Resonance Imaging Clinics of North America - July 5, 2023 Category: Radiology Authors: Liisa L. Bergmann, Jeanne B. Ackman, Jitka Starekova, Alexander Moeller, Scott Reeder, Scott K. Nagle, Mark L. Schiebler Source Type: research

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Source: Magnetic Resonance Imaging Clinics of North America - July 5, 2023 Category: Radiology Source Type: research

MR Angiography: From Head to Toe
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - July 5, 2023 Category: Radiology Authors: Prashant Nagpal, Thomas M. Grist Source Type: research

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Source: Magnetic Resonance Imaging Clinics of North America - July 5, 2023 Category: Radiology Source Type: research