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Introduction
We are delighted to introduce our new co-Consulting Editor of Magnetic Resonance Imaging Clinics of North America, Dr Jenny Bencardino. She will join Dr Suresh Mukherji in guiding the editorial focus of the series. (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - October 7, 2023 Category: Radiology Authors: John Vassallo, Jenny T. Bencardino Source Type: research

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Blood perfusion is an essential metabolic process responsible for the delivery of nutrients and removal of metabolic waste products. MR perfusion imaging is an important physiologic imaging technique that has been “around” since our residency years in the “last century”! Historically, perfusion imaging has been limited to academic centers and research trials. However, numerous technical innovations in MR hardware and software over the past 10 years have improved the quality of the MR perfusion data, r esulting in new clinical applications that can be used in daily practice. (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - October 7, 2023 Category: Radiology Authors: Suresh K. Mukherji, Jenny T. Bencardino Tags: Foreword Source Type: research

Dynamic Contrast-Enhanced (DCE) MRI
The non-invasive dynamic contrast-enhanced MRI (DCE-MRI) method provides valuable insights into tissue perfusion and vascularity. Primarily used in oncology, DCE-MRI is typically utilized to assess morphology and contrast agent (CA) kinetics in the tissue of interest. Interpretation of the temporal signatures of DCE-MRI data includes qualitative, semi-quantitative, and quantitative approaches. Recent advances in MRI technology allow simultaneous high spatial and temporal resolutions in DCE-MRI data acquisition on most vendor platforms, enabling the more desirable approach of quantitative data analysis using pharmacokinetic...
Source: Magnetic Resonance Imaging Clinics of North America - October 6, 2023 Category: Radiology Authors: Xin Li, Wei Huang, James H. Holmes Source Type: research

MR Perfusion Imaging: Technical Advances and Clinical Applications
It has been both a pleasure and an honor to serve as the Guest Editors for this special issue of Magnetic Resonance Imaging Clinics of North America, which is focused on MR perfusion imaging. We extend our sincere gratitude to the Editors for entrusting us with this role and for providing us the latitude to curate this impressive collection of articles. We also wish to thank all contributing authors for their expertise, exceptional contributions, and timely submissions, which have made this issue possible. (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - October 5, 2023 Category: Radiology Authors: Ananth J. Madhuranthakam, Max Wintermark Tags: Preface Source Type: research

PET/MR Imaging in Head and Neck Cancer
Head and neck squamous cell carcinoma (HNSCC) can either be examined with hybrid PET/MR imaging systems or sequentially, using PET/CT and MR imaging. Regardless of the acquisition technique, the superiority of MR imaging compared to CT lies in its potential to interrogate tumor and surrounding tissues with different sequences, including perfusion and diffusion. For this reason, PET/MR imaging is preferable for the detection and assessment of locoregional residual/recurrent HNSCC after therapy. In addition, MR imaging interpretation is facilitated when combined with PET. Nevertheless, distant metastases and distant second p...
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Authors: Minerva Becker, Claudio de Vito, Nicolas Dulguerov, Habib Zaidi Source Type: research

CME Accreditation Page
(Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Source Type: research

Clinical Value of Hybrid PET/MRI
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Authors: Minerva Becker, Valentina Garibotto Source Type: research

Copyright
ELSEVIER (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Source Type: research

Contributors
SURESH K. MUKHERJI, MD, MBA, FACR (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Source Type: research

Contents
Suresh K. Mukherji and Lynne S. Steinbach (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Source Type: research

Forthcoming Issues
MR Perfusion (Source: Magnetic Resonance Imaging Clinics of North America)
Source: Magnetic Resonance Imaging Clinics of North America - September 22, 2023 Category: Radiology Source Type: research

MR Perfusion Imaging for Gliomas
Accurate diagnosis and treatment evaluation of patients with gliomas is imperative to make clinical decisions. Multiparametric MR perfusion imaging reveals physiologic features of gliomas that can help classify them according to their histologic and molecular features as well as distinguish them from other neoplastic and nonneoplastic entities. It is also helpful in distinguishing tumor recurrence or progression from radiation necrosis, pseudoprogression, and pseudoresponse, which is difficult with conventional MR imaging. This review provides an update on MR perfusion imaging for the diagnosis and treatment monitoring of ...
Source: Magnetic Resonance Imaging Clinics of North America - August 22, 2023 Category: Radiology Authors: Jina Lee, Melissa M. Chen, Ho-Ling Liu, F. Eymen Ucisik, Max Wintermark, Vinodh A. Kumar Source Type: research

Clinical Interpretation of Intravoxel Incoherent Motion Perfusion Imaging in the Brain
Intravoxel incoherent motion (IVIM) perfusion imaging extracts information on blood motion in biological tissue from diffusion-weighted MR images. The method is attractive from a clinical stand point, because it measures in essence local quantitative perfusion, without intravenous contrast injection. Currently, the clinical interpretation of IVIM perfusion maps focuses on the IVIM perfusion fraction maps, but improvements in image quality of the IVIM pseudo-diffusion maps, using advanced postprocessing tools involving artificial intelligence, could lead to an increased interest in this parameters, as it could provide addit...
Source: Magnetic Resonance Imaging Clinics of North America - August 21, 2023 Category: Radiology Authors: Christian Federau Source Type: research

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I was very impressed and somewhat surprised by Drs Minerva Becker and Valentina Garibotto ’s candor regarding the evolution of PET-MR imaging in their preface. Instead of touting PET/MR imaging as a “wonder modality,” they give an elegant and accurate description of the history of PET-MR imaging using the analogy of the Gartner “Hype Cycle.” The initial excitement of high expec tations was followed by the realities of trying to demonstrate the tangible benefits of combining two important modalities into an hybrid modality to justify the high costs to hospital administrators, payors, and patients. (Source: Magneti...
Source: Magnetic Resonance Imaging Clinics of North America - August 21, 2023 Category: Radiology Authors: Suresh K. Mukherji, Lynne Steinbach Tags: Foreword Source Type: research

PET/MR Imaging in Clinical Practice: After Expectations and (Some) Disillusion, a Slope of Enlightenment
Like many other technical innovations, PET/MR hybrid imaging has followed Gartner ’s hype cycle theory that the innovation trigger leads to a peak of inflated expectations, followed by a dip of disillusionment, and finally, a slope of enlightenment leading to a plateau of productivity. Since its introduction in the clinical field in 2010, the method has raised very high expecta tions across almost all clinical applications. The previous issue of the Magnetic Resonance Imaging Clinics of North America about this topic published in 2017 was still influenced by the initial enthusiasm. (Source: Magnetic Resonance Imaging Cli...
Source: Magnetic Resonance Imaging Clinics of North America - August 20, 2023 Category: Radiology Authors: Minerva Becker, Valentina Garibotto Tags: Preface Source Type: research