Evaluation of Usefulness of Propiverine Hydrochloride in Poor Responders to Previous Anticholinergics
LUTS: Lower Urinary Tract Symptoms,Volume 10, Issue 2, Page 116-121, May 2018. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 5, 2016 Category: Urology & Nephrology Authors: Naoya MASUMORI , Yuya FUNATO , Yasunobu YAMAGUCHI , Kunio ITOH Source Type: research

Tadalafil Improves Symptoms, Erectile Function and Quality of Life in Patients with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (KYU ‐PRO Study)
ConclusionsThese results indicate that tadalafil 5 mg once daily would be effective and well tolerated treatment in Japanese men with BPH‐LUTS. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 5, 2016 Category: Urology & Nephrology Authors: Ryosuke TAKAHASHI, Minoru MIYAZATO, Hisae NISHII, Yasuhiro SUMINO, Kazuo TAKAYAMA, Masako ONZUKA, Takuma OSHIRO, Seiichi SAITO, Naohiro FUJIMOTO, Hiromitsu MIMATA, Masatoshi ETO Tags: ORIGINAL ARTICLE Source Type: research

Tadalafil 5 mg Once Daily Improves Lower Urinary Tract Symptoms and Erectile Dysfunction: A Systematic Review and Meta ‐analysis
ObjectivesWe carried out a systematic review and meta‐analysis to assess tadalafil 5 mg once‐daily for the treatment of lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). MethodsA literature review was performed to identify all published randomized double‐blind, placebo‐controlled trials of tadalafil 5 mg once‐daily for the treatment of LUTS and ED. The search included the following databases: MEDLINE, EMBASE, and the Cochrane Controlled Trials Register. The reference lists of the retrieved studies were also investigated. ResultsThirteen publications involving a total of 3973 patients were used in...
Source: LUTS: Lower Urinary Tract Symptoms - November 5, 2016 Category: Urology & Nephrology Authors: Yilin WANG, Yiping BAO, Jie LIU, Lijun DUAN, Yuanshan CUI Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of Usefulness of Propiverine Hydrochloride in Poor Responders to Previous Anticholinergics
In this study, a specific drug use–results survey was conducted in poor responders to other anticholinergics to evaluate the usefulness of propiverine hydrochloride. MethodsIn this survey, propiverine hydrochloride was administered for 12 weeks to poor responders to previous anticholinergics, and its usefulness was evaluated by the overactive bladder symptom score (OABSS). ResultsA total of 3851 subjects at 680 institutions were enrolled in the survey. Of the 3624 subjects included in the safety evaluation (male 1899, female 1725, mean age 73.4 years), 2932 were included in the efficacy evaluation (male...
Source: LUTS: Lower Urinary Tract Symptoms - November 5, 2016 Category: Urology & Nephrology Authors: Naoya MASUMORI, Yuya FUNATO, Yasunobu YAMAGUCHI, Kunio ITOH Tags: ORIGINAL ARTICLE Source Type: research

Issue information
(Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 13, 2016 Category: Urology & Nephrology Tags: Issue information Source Type: research

Comparative Efficacy and Tolerability of Antimuscarinic Agents and the Selective β3‐Adrenoceptor Agonist, Mirabegron, for the Treatment of Overactive Bladder: Which is More Preferable as an Initial Treatment?
ConclusionThe present study suggests that mirabegron seems to have priority as an initial therapy with a distinct efficacy/tolerability balance. Mirabegron also represents a reasonable alternative to antimuscarinics for patients who had insufficient efficacy and poor tolerability. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Minoru KOBAYASHI, Akinori NUKUI, Takao KAMAI Tags: ORIGINAL ARTICLE Source Type: research

Radiation Exposure During Videourodynamics: Establishing Risk Factors
ConclusionsWe have shown that increased radiation exposure as measure with Dose Area Product during VUDS was significantly associated with larger BMI, female gender, larger bladder capacity, presence of VUR, junior operator, and higher number of fill cycles. Further studies are now underway to attempt to reduce exposure based on these findings. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Benjamin M. BRUCKER, Lysanne CAMPEAU, Eva FONG, Sidhartha KALRA, Nirit ROSENBLUM, Victor W. NITTI Tags: ORIGINAL ARTICLE Source Type: research

Impact of Androgen Deprivation Therapy on Volume Reduction and Lower Urinary Tract Symptoms in Patients with Prostate Cancer
ConclusionsIn this study, we observed that ADT significantly reduced TPV and improved LUTS in patients with PCa and moderate to severe LUTS, but increased nocturia in patients with mild LUTS. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Satoshi WASHINO, Masaru HIRAI, Kimitoshi SAITO, Yutaka KOBAYASHI, Yoshiaki ARAI, Tomoaki MIYAGAWA Tags: ORIGINAL ARTICLE Source Type: research

Long ‐term Persistence with Mirabegron versus Solifenacin in Women with Overactive Bladder: Prospective, Randomized Trial
ObjectivesTo compare persistence with medication and the reasons for discontinuation of mirabegron or solifenacin therapy up to12 months in women with overactive bladder (OAB). MethodsFemale OAB patients who presented to women's urology clinics were enrolled in a prospective, randomized, two‐arm study. Patients were randomized to receive mirabegron at 25–50 mg (n = 76) or solifenacin at 2.5–5 mg (n = 72). The persistence rate and the reasons for discontinuation were investigated up to 12 months. ResultsThe 12‐month persistence rate was 12.2% in the mir...
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Manami KINJO, Yuki SEKIGUCHI, Yasukuni YOSHIMURA, Kikuo NUTAHARA Tags: ORIGINAL ARTICLE Source Type: research

Comment on: “Effect on Sexual Function of Patients and Patients' Spouses After Midurethal Sling Procedure for Stress Urinary Incontinence: A Prospective Single Center Study”
(Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Antonio Simone LAGAN À, Valentina Lucia LA ROSA, Agnese Maria Chiara RAPISARDA, Salvatore Giovanni VITALE Tags: LETTER TO THE EDITOR Source Type: research

Safety and Effectiveness of Mirabegron in Patients with Overactive Bladder in a Real ‐World Clinical Setting: A Japanese Post‐Marketing Study
This study examined prescribing patterns, adverse drug reaction (ADR) incidence, and treatment effectiveness. MethodsFull medical histories, including prior/concomitant drug use, were collected before initiating mirabegron treatment. After 12 weeks mirabegron, physicians assessed ADR incidence and treatment effectiveness. Residual urine volume was assessed and patients completed the Overactive Bladder Symptom Score (OABSS) and International Prostate Symptom Score‐Quality of Life (I‐PSS QoL) surveys at Baseline and 12 weeks. Data were collected between April 2012 and July 2014. ResultsOf 9795 OAB patients ...
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Yumiko NOZAWA, Daisuke KATO, Hiromi TABUCHI, Kentarou KUROISHI Tags: ORIGINAL ARTICLE Source Type: research

Serum Testosterone Levels Are Negatively Correlated with International Prostate Symptom Score and Transitional Prostate Volume
ConclusionsAs total testosterone levels decrease, both International Prostate Symptom Score and transitional prostate volume increase significantly. These findings provide evidence of the presence of more severe lower urinary tract symptoms and larger transitional prostate volume in aging men. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Ji S. SHIM, Jae H. KIM, Yong S. YOON, Hoon CHOI, Jae Y. PARK, Jae H. BAE Tags: ORIGINAL ARTICLE Source Type: research

Testing of a New Portable Device for Dynamic Bladder Pressure Monitoring
ConclusionThe portable dynamic bladder pressure monitoring device is conducive to the dynamic monitoring of bladder pressure in patients with neurogenic bladder caused by spinal cord injury. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Lingfeng LIU, Kang ZHAO, Fan CHEN, Jian WU, Zhaofeng YANG, Ming CHEN, Linbo MAO, Jiurong HAN Tags: ORIGINAL ARTICLE Source Type: research

Potential Primary Endpoint for Exploratory Clinical Trial in Patients with Overactive Bladder: A Systematic Literature Review
ConclusionsOur findings suggest that volume voided per micturition is a useful symptom for evaluating OAB candidate compounds in a small sample size and represents an effective primary endpoint, especially in exploratory clinical trials. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2016 Category: Urology & Nephrology Authors: Shingo IINO, Masayuki KANEKO, Mamoru NARUKAWA Tags: ORIGINAL ARTICLE Source Type: research

Association Between Ambient Temperature and Lower Urinary Tract Symptoms: A Hospital ‐Based Cross‐Sectional Analysis
ObjectivesTo date, there is no overall agreement as to risk of ambient temperature for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Thus, we focused on ambient temperature as an environmental factor affecting LUTS and attempted to explain the temperature differences in LUTS severity in cases in real clinical practice. MethodsThis was a multicenter, cross‐sectional survey. The study involved 1612 men aged 40 years and older who visited 23 university hospitals in 10 major areas in South Korea between September 2010 and December 2011. The participants who had good overall mental and physic...
Source: LUTS: Lower Urinary Tract Symptoms - July 20, 2016 Category: Urology & Nephrology Authors: Sung Ryul SHIM, Jae Heon KIM, Seung Whan DOO, Won Jae YANG, Eun Seop SONG, Yun Seob SONG Tags: ORIGINAL ARTICLE Source Type: research

Association Between Ambient Temperature and Lower Urinary Tract Symptoms: A Hospital‐Based Cross‐Sectional Analysis
ObjectivesTo date, there is no overall agreement as to risk of ambient temperature for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Thus, we focused on ambient temperature as an environmental factor affecting LUTS and attempted to explain the temperature differences in LUTS severity in cases in real clinical practice. MethodsThis was a multicenter, cross‐sectional survey. The study involved 1612 men aged 40 years and older who visited 23 university hospitals in 10 major areas in South Korea between September 2010 and December 2011. The participants who had good overall mental and physic...
Source: LUTS: Lower Urinary Tract Symptoms - July 20, 2016 Category: Urology & Nephrology Authors: Sung Ryul SHIM, Jae Heon KIM, Seung Whan DOO, Won Jae YANG, Eun Seop SONG, Yun Seob SONG Tags: ORIGINAL ARTICLE Source Type: research

Role of Bladder Dysfunction in Men with Lower Urinary Tract Symptoms Refractory to Alpha ‐blocker Therapy: A Video‐urodynamic Analysis
ConclusionApproximately one‐third of male LUTS was due to bladder dysfunction. A man older than 70 years with LUTS and TPV less than 30 mL usually indicates the presence of bladder dysfunction rather than BOO. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - July 1, 2016 Category: Urology & Nephrology Authors: Yuan ‐Hong JIANG, Chun‐Hou LIAO, Hann‐Chorng KUO Tags: ORIGINAL ARTICLE Source Type: research

Health Related Quality of Life in Patients with Side ‐Effects after Antimuscarinic Treatment for Overactive Bladder
This study was designed to investigate the patients' satisfaction by quality weight of health status as affected by the side‐effects of OAB medications. Patients who had OAB symptoms lasting longer than 3 months and have experienced side‐effects after any antimuscarinic treatments filled in the EQ‐5D questionnaire. The enrolled patients had two EQ‐5D questionnaires for two different health statuses, i.e., presence or absence of side‐effects. Quality weight was calculated using the ED‐5D health status score with Korean tariff. ResultsOne hundred patients were enrolled and completed the HR‐QoL questionnaire. Th...
Source: LUTS: Lower Urinary Tract Symptoms - June 12, 2016 Category: Urology & Nephrology Authors: Aram KIM, Kyu ‐Sung LEE, Rangrhee JUNG, Selee NA, Joon‐chul KIM, Hyeong Gon KIM, Myung‐Soo CHOO Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of Voiding Parameters in Healthy Women Using Sound Analysis
ObjectivesSonouroflowmetry represents a novel method for estimating urinary flow parameters. The aim of this study was to compare the urinary flow parameters acquired using sonouroflowmetry with those of standard uroflowmetry in healthy female volunteers. MethodsThirty‐six healthy female volunteers (aged 25–54 years) were subjected to standard uroflowmetry. Simultaneously, subjects dialed a dedicated number on a mobile phone and kept recording until urination was finished. Sound data were analyzed and compared to the uroflowmetry data. Of 218 recordings, 183 were included in the final analysis. Thirty‐four...
Source: LUTS: Lower Urinary Tract Symptoms - June 12, 2016 Category: Urology & Nephrology Authors: Marcel GÄRTNER, Jan KRHUT, Petr HURTIK, Michal BURDA, Katarina ZVAROVA, Peter ZVARA Tags: ORIGINAL ARTICLE Source Type: research

Health Related Quality of Life in Patients with Side‐Effects after Antimuscarinic Treatment for Overactive Bladder
This study was designed to investigate the patients' satisfaction by quality weight of health status as affected by the side‐effects of OAB medications. Patients who had OAB symptoms lasting longer than 3 months and have experienced side‐effects after any antimuscarinic treatments filled in the EQ‐5D questionnaire. The enrolled patients had two EQ‐5D questionnaires for two different health statuses, i.e., presence or absence of side‐effects. Quality weight was calculated using the ED‐5D health status score with Korean tariff. ResultsOne hundred patients were enrolled and completed the HR‐QoL questionnaire. Th...
Source: LUTS: Lower Urinary Tract Symptoms - June 12, 2016 Category: Urology & Nephrology Authors: Aram KIM, Kyu‐Sung LEE, Rangrhee JUNG, Selee NA, Joon‐chul KIM, Hyeong Gon KIM, Myung‐Soo CHOO Tags: ORIGINAL ARTICLE Source Type: research

Physiological Roles of Bradykinin and Involvement of Bradykinin B2 Receptor in Urethral Function in Humans and Animals
ConclusionsThe present study provides evidence that bradykinin elicits urethral smooth muscle contraction via the bradykinin B2 receptor, suggesting the potential utility of this receptor as a novel target for the treatment of voiding dysfunction. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 11, 2016 Category: Urology & Nephrology Authors: Kenichiro FUJIMOTO, Taiji YOSHINO, Satoko NAKAJIMA, Hironori YUYAMA, Noriyuki MASUDA, Masahiro TAKEDA Tags: ORIGINAL ARTICLE Source Type: research

Intratesticular Bradykinin Involvement in Rat Testicular Pain Models
ConclusionsHere, we found that intratesticular bradykinin evokes pain behavior via stimulation of bradykinin B2 receptors and that intratesticular acetic acid injection induces intratesticular bradykinin synthesis, consequently leading to pain behavior. These findings suggest that the potential utility of bradykinin B2 receptor antagonists as a novel target for treating urogenital pain. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 11, 2016 Category: Urology & Nephrology Authors: Kenichiro FUJIMOTO, Taiji YOSHINO, Katsuro YOSHIOKA, Hironori YUYAMA, Noriyuki MASUDA, Masahiro TAKEDA Tags: ORIGINAL ARTICLE Source Type: research

Treatment Outcome of Overactive Bladder Patients Receiving Antimuscarinic Therapy for More than One Year
ConclusionSustained therapeutic effects were observed in patients who received 12 months or more of antimuscarinic therapy, even in elderly patients. In addition, side‐effects in patients receiving long‐term therapy were also common but tolerable. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2016 Category: Urology & Nephrology Authors: Sheng ‐Mou HSIAO, Ho‐Hsiung LIN, Hann‐Chorng KUO Tags: ORIGINAL ARTICLE Source Type: research

International Prostate Symptom Score Should Be Considered a Complement Rather Than a Substitute to Generic Preference ‐Based Measures for Measuring Lower Urinary Tract Symptoms Within Economic Evaluation
ConclusionOur findings suggest that the IPSS has comparable discriminant validity to the GQoL instruments and therefore useful for assessing subgroup differences related to urinary symptoms. The weak convergence between the IPSS and the GQoL instruments however suggests that, within economic evaluation, the IPSS should be viewed as a complement rather than a substitute to the GQoL instruments because it captures different quality of life constructs. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2016 Category: Urology & Nephrology Authors: Christine MPUNDU ‐KAAMBWA, Billingsley KAAMBWA, Sarah APPLETON, Sean MARTIN, Gary WITTERT, Robert ADAMS Tags: ORIGINAL ARTICLE Source Type: research

Impact of Living at the Japanese Antarctic Research Expedition Base on Urinary Status
ConclusionThis is the first survey of the urinary status of people living in a polar environment. The findings obtained by questionnaires and voiding dairies indicated that urination and sleep status did not worsen during the stay in Antarctica. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2016 Category: Urology & Nephrology Authors: Atsushi IKEDA, Koji KAWAI, Masakazu TSUTSUMI, Koji YOSHIMURA, Giichiro OHNO, Tatsuhisa HASEGAWA, Hirofumi OOE, Kentaro WATANABE, Jun MIYAZAKI, Hiroyuki NISHIYAMA Tags: ORIGINAL ARTICLE Source Type: research

Role of Bladder Dysfunction in Men with Lower Urinary Tract Symptoms Refractory to Alpha‐blocker Therapy: A Video‐urodynamic Analysis
ConclusionApproximately one‐third of male LUTS was due to bladder dysfunction. A man older than 70 years with LUTS and TPV less than 30 mL usually indicates the presence of bladder dysfunction rather than BOO. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2016 Category: Urology & Nephrology Authors: Yuan‐Hong JIANG, Chun‐Hou LIAO, Hann‐Chorng KUO Tags: ORIGINAL ARTICLE Source Type: research

Associations of Psychometric Affective Parameters with Urodynamic Investigation for Urinary Frequency
ConclusionThis pilot study revealed an association between psychometric parameters and urodynamic results indicating a common pathway of bladder function and affective complaints. Further research is needed to elucidate which parts of the bladder‐brain axis are involved and how these parts correspond by means of urodynamics. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2016 Category: Urology & Nephrology Authors: Desiree M. J. VRIJENS, Jamie M. A. F. L. DROSSAERTS, Kevin RADEMAKERS, Martijn SMITS, Stefan G. DE WACHTER, Carsten LEUE, Gommert A. VAN KOEVERINGE Tags: ORIGINAL ARTICLE Source Type: research

Prospective Randomized Comparison of Monopolar TURP, Bipolar TURP and Photoselective Vaporization of the Prostate in Patients with Benign Prostatic Obstruction: 36 Months Outcome
ConclusionMonopolar TURP, Bipolar TURP and PVP provides durable and comparable efficacy at 36 months follow up in patients with prostate size
Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2016 Category: Urology & Nephrology Authors: Niraj KUMAR, Pawan VASUDEVA, Anup KUMAR, Harbinder SINGH Tags: ORIGINAL ARTICLE Source Type: research

Issue information
(Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 25, 2016 Category: Urology & Nephrology Tags: Issue information Source Type: research

Initial Use of High ‐Dose Anticholinergics Combined with Alpha‐Blockers for Male Lower Urinary Tract Symptoms with Overactive Bladder: A Prospective, Randomized Preliminary Study
ObjectivesTo evaluate the clinical efficacy of initial combined treatment of alpha‐blocker plus dose‐dependent anticholinergic agent compared to the alpha‐blocker monotherapy in benign prostatic hyperplasia patients with overactive bladder. MethodsMale lower urinary tract symptoms (LUTS) patients with International Prostate Symptom Score (IPSS) of 8 or higher, total overactive bladder Symptom Score (OABSS) of 3 or higher, and 2 points or higher in the OABSS questionnaire number 2 were enrolled. Eligible subjects (total n = 146) were randomly assigned to receive tamsulosin 0.2 mg (Group I, n&thins...
Source: LUTS: Lower Urinary Tract Symptoms - March 29, 2016 Category: Urology & Nephrology Authors: Kyu Won LEE, Kyung Jae HUR, Sang Hoon KIM, Su Yeon CHO, Sang Rak BAE, Bong Hee PARK, Yong Seok LEE, Chang Hee HAN, Hyun Woo KIM Tags: ORIGINAL ARTICLE Source Type: research

Efficacy of Adding Dutasteride to α‐Blocker Therapy Treated Benign Prostatic Hyperplasia Patients with Small Volume Prostate (
Conclusions:Benign prostatic hyperplasia in LUTS patients with small prostates did not show a sustainable benefit from the addition of dutasteride to α‐blocker therapy. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 16, 2016 Category: Urology & Nephrology Authors: Mamoru HASHIMOTO, Nobutaka SHIMIZU, Koichi SUGIMOTO, Sachiko HONGOH, Takafumi MINAMI, Masahiro NOZAWA, Kazuhiro YOSHIMURA, Akihide HIRAYAMA, Hideo TAHARA, Hirotsugu UEMURA Tags: ORIGINAL ARTICLE Source Type: research

Issue information ‐ IFA
(Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 20, 2016 Category: Urology & Nephrology Tags: Issue information ‐ IFA Source Type: research

Issue information ‐ TOC
(Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 20, 2016 Category: Urology & Nephrology Tags: Issue information ‐ TOC Source Type: research

Lowest Acceptable Bladder Capacity for Interpretation of Uroflowmetry Tests in Children
ObjectiveTo determine the age‐specific lowest acceptable value of bladder capacity (LABC) for interpretation of uroflowmetry tests in children. MethodsFrom September 2008 through July 2012, healthy children aged 4–9 years were enrolled. All children were asked to have two sets of uroflowmetry and post‐void residual (PVR) tests. We selected the tests with lower bladder capacity (voided volume+ PVR) of each child to analyze the LABC. Only bell shaped curves were regarded as normal. PVR>20 mL and Qmax 10 mL, Qmax
Source: LUTS: Lower Urinary Tract Symptoms - January 1, 2016 Category: Urology & Nephrology Authors: Shang‐Jen CHANG, Judy Y.‐C. CHEN, I‐Ni CHIANG, Stephen S.‐D. YANG Tags: ORIGINAL ARTICLE Source Type: research

Initial Use of High‐Dose Anticholinergics Combined with Alpha‐Blockers for Male Lower Urinary Tract Symptoms with Overactive Bladder: A Prospective, Randomized Preliminary Study
ObjectivesTo evaluate the clinical efficacy of initial combined treatment of alpha‐blocker plus dose‐dependent anticholinergic agent compared to the alpha‐blocker monotherapy in benign prostatic hyperplasia patients with overactive bladder. MethodsMale lower urinary tract symptoms (LUTS) patients with International Prostate Symptom Score (IPSS) of 8 or higher, total overactive bladder Symptom Score (OABSS) of 3 or higher, and 2 points or higher in the OABSS questionnaire number 2 were enrolled. Eligible subjects (total n = 146) were randomly assigned to receive tamsulosin 0.2 mg (Group I, n&thins...
Source: LUTS: Lower Urinary Tract Symptoms - January 1, 2016 Category: Urology & Nephrology Authors: Kyu Won LEE, Kyung Jae HUR, Sang Hoon KIM, Su Yeon CHO, Sang Rak BAE, Bong Hee PARK, Yong Seok LEE, Chang Hee HAN, Hyun Woo KIM Tags: ORIGINAL ARTICLE Source Type: research

Urothelial Dysfunction and Chronic Inflammation in Diabetic Patients with Overactive Bladder
ObjectivesTo investigate urothelial dysfunction, suburothelial inflammation, and muscarinic receptor expression in diabetic patients with overactive bladder (OAB). MethodsA total 19 patients with OAB and diabetes mellitus (DM), 14 OAB patients without DM, and 10 healthy control subjects were enrolled in the study. Immunofluorescence staining of E‐cadherin, zonula occludens‐1 (ZO‐1), tryptase (mast cell activation), and apoptosis tests on the bladder urothelium and suburothelium were performed. Tissue muscarinic receptor M2, M3, and purinergic receptor P2X3 levels were measured by Western blotting. Video urodynamic st...
Source: LUTS: Lower Urinary Tract Symptoms - January 1, 2016 Category: Urology & Nephrology Authors: Chung‐Cheng WANG, Hann‐Chorng KUO Tags: ORIGINAL ARTICLE Source Type: research

Prediction of Mid ‐Urethral Sling Failure with Clinical Findings and Urodynamics
ObjectiveMid‐urethral slings (MUS) become a standard, minimally invasive surgery to treat urinary stress incontinence. Our aim is to investigate the contribution of preoperative urodynamics to mid‐urethral slings success and determine predictors for choosing mid‐urethral sling route. MethodsWomen with stress urinary incontinence and who desired surgical correction of their incontinence were included in the study. The selection of the procedure was according to an algorithm used in an institution. Urodynamic and baseline factors that may be associated with surgery failure were analyzed. ResultsA total of 159 patients ...
Source: LUTS: Lower Urinary Tract Symptoms - December 4, 2015 Category: Urology & Nephrology Authors: Serdar AYDIN, Çağrı ARIOĞLU AYDIN, Fırat ERSAN Tags: ORIGINAL ARTICLE Source Type: research

Coping and Help‐Seeking Behaviors for Management of Urinary Incontinence
ConclusionsWhile women mostly do not prefer to seek medical advice for UI, men tend to go to doctors more often than women. Except for treatment seeking behaviors, both men and women are practicing coping methods for the management of UI such as going frequently to the toilet, keeping feet warm, hot application to perineum etc. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 1, 2015 Category: Urology & Nephrology Authors: Dilek BILGIC, Nezihe KIZILKAYA BEJI, Ayfer OZBAS, Ikbal CAVDAR, Ergul ASLAN, Onay YALCIN Tags: ORIGINAL ARTICLE Source Type: research

Coping and Help ‐Seeking Behaviors for Management of Urinary Incontinence
ConclusionsWhile women mostly do not prefer to seek medical advice for UI, men tend to go to doctors more often than women. Except for treatment seeking behaviors, both men and women are practicing coping methods for the management of UI such as going frequently to the toilet, keeping feet warm, hot application to perineum etc. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 1, 2015 Category: Urology & Nephrology Authors: Dilek BILGIC, Nezihe KIZILKAYA BEJI, Ayfer OZBAS, Ikbal CAVDAR, Ergul ASLAN, Onay YALCIN Tags: ORIGINAL ARTICLE Source Type: research

Cost‐Effectiveness Analysis of Long‐Term Intermittent Self‐Catheterization with Hydrophilic‐Coated and Uncoated Catheters in Patients with Spinal Cord Injury in Japan
ConclusionsThe ICER of 3.8 million yen (US$ 31 405) falls well within the Japanese societal willingness to pay per QALY gained; therefore, hydrophilic‐coated catheters can be considered highly cost‐effective in Japan compared with uncoated catheters. However, because of the lack of relevant studies, a number of key parameters could not be based on Japanese data, and further research among people with SCI in Japan is recommended. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 30, 2015 Category: Urology & Nephrology Authors: Toyohiko WATANABE, Shingo YAMAMOTO, Momokazu GOTOH, Tadanori SAITOH, Osamu YOKOYAMA, Tatsunori MURATA, Masayuki TAKEDA Tags: ORIGINAL ARTICLE Source Type: research

Pathophysiological and Therapeutic Considerations for Non ‐Neurogenic Lower Urinary Tract Dysfunction in Children
Non‐neurogenic lower urinary tract dysfunction (LUTD) in children is very common in clinical practice and is important as an underlying cause of lower urinary tract symptoms, urinary tract infection and vesicoureteral reflux in affected children. LUTD in children is caused by multiple factors and might be related with a delay in functional maturation of the lower urinary tract. Behavioral and psychological problems often co‐exist in children with LUTD and bowel dysfunction. Recent findings in functional brain imaging suggest that bladder bowel dysfunction and behavioral and psychiatric disorders in children might share...
Source: LUTS: Lower Urinary Tract Symptoms - November 30, 2015 Category: Urology & Nephrology Authors: Hidehiro KAKIZAKI, Masafumi KITA, Masaki WATANABE, Naoki WADA Tags: REVIEW ARTICLE Source Type: research

Cost ‐Effectiveness Analysis of Long‐Term Intermittent Self‐Catheterization with Hydrophilic‐Coated and Uncoated Catheters in Patients with Spinal Cord Injury in Japan
ConclusionsThe ICER of 3.8 million yen (US$ 31 405) falls well within the Japanese societal willingness to pay per QALY gained; therefore, hydrophilic‐coated catheters can be considered highly cost‐effective in Japan compared with uncoated catheters. However, because of the lack of relevant studies, a number of key parameters could not be based on Japanese data, and further research among people with SCI in Japan is recommended. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 30, 2015 Category: Urology & Nephrology Authors: Toyohiko WATANABE, Shingo YAMAMOTO, Momokazu GOTOH, Tadanori SAITOH, Osamu YOKOYAMA, Tatsunori MURATA, Masayuki TAKEDA Tags: ORIGINAL ARTICLE Source Type: research

High ‐Frequency Continuous Pulsed Magnetic Stimulation Does Not Adversely Affect Development on Whole Body Organs in Female Sprague–Dawley Rats
ConclusionsPulsed magnetic stimulation exerted no apparent adverse effect on the various organs, hormone levels, body weight, and daily behaviors in female rats. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - October 15, 2015 Category: Urology & Nephrology Authors: Eiichi SATO, Tomonori YAMANISHI, Yasuo IMAI, Masashi KOBAYASHI, Taku SAKAMOTO, Yuko ONO, Akiko FUJII, Takehiko YAMAGUCHI, Tsukasa NAKAMURA, Yoshihiko UEDA Tags: ORIGINAL ARTICLE Source Type: research

Degarelix Versus Goserelin Plus Bicalutamide in the Short ‐Term Relief of Lower Urinary Tract Symptoms in Prostate Cancer Patients: Results of a Pooled Analysis
ConclusionAn early, significant and clinically more pronounced improvement of LUTS, especially in patients with moderate‐to‐severe LUTS or advanced PCa, was seen with degarelix vs. goserelin plus bicalutamide. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - October 7, 2015 Category: Urology & Nephrology Authors: Malcolm MASON, Pierre RICHAUD, Zsolt BOSNYAK, Anders MALMBERG, Anders NEIJBER Tags: ORIGINAL ARTICLE Source Type: research

Naftopidil Improves Symptoms in a Rat Model of Tranilast ‐Induced Interstitial Cystitis
ConclusionNaftopidil improved the symptoms of tranilast‐induced IC, such as reduced locomotor activity due to pelvic pain and a shortened interval between bladder contractions. Therefore, naftopidil may be a potential treatment for IC. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 26, 2015 Category: Urology & Nephrology Authors: Kimio SUGAYA, Saori NISHIJIMA, Katsumi KADEKAWA, Katsuhiro ASHITOMI, Tomoyuki UEDA, Hideyuki YAMAMOTO Tags: ORIGINAL ARTICLE Source Type: research

Prediction of Mid‐Urethral Sling Failure with Clinical Findings and Urodynamics
ObjectiveMid‐urethral slings (MUS) become a standard, minimally invasive surgery to treat urinary stress incontinence. Our aim is to investigate the contribution of preoperative urodynamics to mid‐urethral slings success and determine predictors for choosing mid‐urethral sling route. MethodsWomen with stress urinary incontinence and who desired surgical correction of their incontinence were included in the study. The selection of the procedure was according to an algorithm used in an institution. Urodynamic and baseline factors that may be associated with surgery failure were analyzed. ResultsA total of 159 patients ...
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2015 Category: Urology & Nephrology Authors: Serdar AYDIN, Çağrı ARIOĞLU AYDIN, Fırat ERSAN Tags: ORIGINAL ARTICLE Source Type: research

Antioxidant Agent Quercetin Prevents Impairment of Bladder Tissue Contractility and Apoptosis in a Rat Model of Ischemia/Reperfusion Injury
ConclusionQuercetin treatment protects bladder tissue contractility against acute I/R injury by decreasing oxidative stress and apoptosis induced by I/R. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2015 Category: Urology & Nephrology Authors: Ilker TINAY, Tarik E. SENER, Ozge CEVIK, Selin CADIRCI, Hale TOKLU, Sule CETINEL, Göksel SENER, Tufan TARCAN Tags: ORIGINAL ARTICLE Source Type: research

Pathophysiological and Therapeutic Considerations for Non‐Neurogenic Lower Urinary Tract Dysfunction in Children
Non‐neurogenic lower urinary tract dysfunction (LUTD) in children is very common in clinical practice and is important as an underlying cause of lower urinary tract symptoms, urinary tract infection and vesicoureteral reflux in affected children. LUTD in children is caused by multiple factors and might be related with a delay in functional maturation of the lower urinary tract. Behavioral and psychological problems often co‐exist in children with LUTD and bowel dysfunction. Recent findings in functional brain imaging suggest that bladder bowel dysfunction and behavioral and psychiatric disorders in children might share...
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2015 Category: Urology & Nephrology Authors: Hidehiro KAKIZAKI, Masafumi KITA, Masaki WATANABE, Naoki WADA Tags: REVIEW ARTICLE Source Type: research

Effect of Naftopidil on Bladder Microcirculation in a Rat Model of Bladder Outlet Obstruction
ConclusionsNaftopidil improved bladder overactivity as well as the impaired bladder blood flow.caused by bladder‐outlet‐obstruction. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2015 Category: Urology & Nephrology Authors: Tsuyoshi MAJIMA, Tokunori YAMAMOTO, Yasuhito FUNAHASHI, Shun TAKAI, Yoshihisa MATSUKAWA, Masaki YOSHIDA, Momokazu GOTOH Tags: ORIGINAL ARTICLE Source Type: research

Clinical Guideline for Female Lower Urinary Tract Symptoms
The “Japanese Clinical Guideline for Female Lower Urinary Tract Symptoms,” published in Japan in November 2013, contains two algorithms (a primary and a specialized treatment algorithm) that are novel worldwide as they cover female lower urinary tract symptoms other than urinary incontinence. For primary treatment, necessary types of evaluation include querying the patient regarding symptoms and medical history, examining physical findings, and performing urinalysis. The types of evaluations that should be performed for select cases include evaluation with symptom/quality of life (QOL) questionnaires, urination...
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2015 Category: Urology & Nephrology Authors: Satoru TAKAHASHI, Mineo TAKEI, Osamu NISHIZAWA, Osamu YAMAGUCHI, Kumiko KATO, Momokazu GOTOH, Yasukuni YOSHIMURA, Masami TAKEYAMA, Hideo OZAWA, Makoto SHIMADA, Tomonori YAMANISHI, Masaki YOSHIDA, Hikaru TOMOE, Osamu YOKOYAMA, Masayasu KOYAMA Tags: GUIDELINE Source Type: research