How do urinary incontinence types affect sexual function and quality of life for Turkish women?
ConclusionThe sexual function of women with MUI was affected more adversely than the other UI subtypes. There was no statistically significant difference between the UI subtypes according to IIQ ‐7 scores, but when we examined the scores, MUI and UUI were found to have more negative effects on QoL. Clinicians and continence nurses should make routine evaluations of sexual function and QoL for women according to UI subtypes. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 27, 2020 Category: Urology & Nephrology Authors: Dilek Bilgic, Nezihe Kizilkaya Beji Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 12, Issue 2, Page 107-107, May 2020. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 26, 2020 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Contemporary use of prescription medications for neurogenic lower urinary tract dysfunction
ConclusionsThis is the first study to analyze the use of medical therapy for NLUTD in a large outpatient setting. Further prospective evaluation of patient satisfaction and efficacy of both single anticholinergic medication and dual therapy is needed. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 23, 2020 Category: Urology & Nephrology Authors: Aidan Kennedy, Alana Christie, Rena D. Malik, Philippe E. Zimmern Tags: ORIGINAL ARTICLE Source Type: research

Longitudinal changes in patient ‐reported outcomes after artificial urinary sphincter implantation
AbstractObjectiveTo evaluate the time course of lower urinary tract symptoms (LUTS) after artificial urinary sphincter (AUS) implantation based on individual longitudinal changes of patient ‐reported outcomes.MethodsThis retrospective study included 66 male patients with severe urinary incontinence who were treated with primary AUS implantation between 2009 and 2019. International Consultation on Incontinence Questionnaire ‐Short Form (ICIQ‐SF) and International Prostate Symptom Score (IPSS) questionnaires were used to evaluate continence status and LUTS preoperatively, 1, 3, and 12 months after activation, an...
Source: LUTS: Lower Urinary Tract Symptoms - April 12, 2020 Category: Urology & Nephrology Authors: Minato Yokoyama, Hitoshi Masuda, Masaya Ito, Yuma Waseda, Shingo Moriyama, Masahiro Toide, Yusuke Uchida, Sho Uehara, Toshiki Kijima, Soichiro Yoshida, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii Tags: ORIGINAL ARTICLE Source Type: research

Our experiences in bipolar radiofrequency thermotherapy system as an alternative treatment in LUTS
In this study we found there was 48.8% increase in Qmax, 72.1% decrease in IPSS, 70.8% decrease in the QoL score, 51.1% decrease in PVR of 80 patients who underwent bipolar radiofrequency prostate ablation. The bipolar radiofrequency prostate thermotherapy system can be safely applied as an outpatient treatment in high‐risk cases or for those who are anxious about surgical interventions. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 30, 2020 Category: Urology & Nephrology Authors: Özbay Engin, Salar Remzi, Öncel Halil Ferat Tags: ORIGINAL ARTICLE Source Type: research

The prevalence of urinary incontinence in men and women aged 40  years or over in China, Taiwan and South Korea: A cross‐sectional, prevalence‐based study
ConclusionUI was associated with substantial problems, including an adverse impact on HRQoL. Medication failed to satisfy many individuals with UI. Efforts to educate the public and physicians about the impact of UI could improve diagnosis and treatment rates. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 24, 2020 Category: Urology & Nephrology Authors: Budiwan Sumarsono, Jar Jar Jong, Jian ‐Ye Wang, Limin Liao, Kyu‐Sung Lee, Tag Keun Yoo, Shih‐Ping Liu, Yao‐Chi Chuang Tags: ORIGINAL ARTICLE Source Type: research

The effect of transobturator tape operation on sexual functions of a patient with stress urinary incontinence and patient's spouse
AbstractPurposeThis prospective study aimed to investigate the effects of transobturator tape (TOT) procedure on patients with stress urinary incontinence (SUI) and their spouses' sexual function.Material and methodsA total of 157 patients with SUI who underwent TOT operation between January 2017 and May 2019 and their spouses were included. All patients enrolled filled out the Incontinence Impact Questionnaire (IIQ ‐7), the Urogenital Distress Inventory (UDI‐6), the Female Sexual Function Index (FSFI), and patients' spouses filled out International Index of Erectile Function (IIEF‐5) before surgery and 6 months afte...
Source: LUTS: Lower Urinary Tract Symptoms - March 13, 2020 Category: Urology & Nephrology Authors: S üleyman Cemil Oğlak, Mehmet Obut Tags: ORIGINAL ARTICLE Source Type: research

Lower urinary tract symptoms and related factors in female university students
ConclusionsLower urinary tract complaints are a common problem. We believe that routine medical screening should be performed for female university students whose living conditions change when they start university; besides, we suggest that well ‐attended and repeatable training programs for healthy living behaviors, urinary habits, and hygiene should be organized for university students. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - February 28, 2020 Category: Urology & Nephrology Authors: Sebahat G ücük, Ülkü M. Ural, Mehmet Kayhan, Adnan Gücük Tags: ORIGINAL ARTICLE Source Type: research

Current management of refractory overactive bladder
AbstractOveractive bladder (OAB) is a common condition affecting one ‐sixth to one‐fifth of the global population. The treatment of refractory OAB remains a challenge for urologists. Current treatment options include the use of combination therapy with antimuscarinic agents and beta‐3 adrenoceptor agonists, and treating underlying curable disorders. Intravesica l botulinum toxin type A (BoNT‐A) injection, percutaneous tibial nerve stimulation, and sacral nerve stimulation are third‐line management therapies suggested by the American Urological Association/Society of Urodynamics, Female Pelvic Medicine& Urogen...
Source: LUTS: Lower Urinary Tract Symptoms - February 20, 2020 Category: Urology & Nephrology Authors: Li ‐Chen Chen, Hann‐Chorng Kuo Tags: REVIEW ARTICLE Source Type: research

Therapeutic effects of Choreito, a traditional Japanese (Kampo) medicine, on detrusor overactivity induced by acetic acid in rats
This study aimed to identify the effects and therapeutic mechanism of CRT on the improvement of detrusor overactivity (DO) using an experimental rat model. Forty ‐five female Sprague‐Dawley rats were equally divided into three groups: intravesical saline instillation with normal food (normal group), intravesical acetic acid (AA) instillation with normal food (AA group), and intravesical AA instillation with CRT (AA with CRT group). To induce a decrease i n bladder capacity, instillation of 0.2% AA was used based on prior studies. Cystometric investigation was employed to clarify the effects of AA and CRT. Microcirculat...
Source: LUTS: Lower Urinary Tract Symptoms - February 4, 2020 Category: Urology & Nephrology Authors: Manabu Ueno, Tomonori Minagawa, Tetsuichi Saito, Tetsuya Imamura, Takashi Nagai, Teruyuki Ogawa, Osamu Ishizuka Tags: ORIGINAL ARTICLE Source Type: research

Quality of life and sexuality after bilateral sacrospinous fixation with vaginal hysterectomy for treatment of primary pelvic organ prolapse
AbstractObjectiveTo investigate the quality of life (QoL) and sexuality in women affected by pelvic organ prolapse (POP) and treated by bilateral sacrospinous ligament fixation (SSLF) with vaginal hysterectomy.MethodsThis is a prospective observational study carried out at Isparta City Hospital from July 2017 to December 2018. A total of 26 sexually active women with symptomatic uterine prolapse POP ‐Q (Pelvic Organ Prolapse Quantification) stage II or higher requiring surgery were included in the study. Short Form Health Survey (SF‐36) was used preoperatively and at 6 months to examine the impacts of vaginal re...
Source: LUTS: Lower Urinary Tract Symptoms - January 30, 2020 Category: Urology & Nephrology Authors: Yakup Yalcin, Melike Demir Caltekin, Serenat Eris Yalcin Tags: ORIGINAL ARTICLE Source Type: research

Flow resistive forces index (QRF): Development and clinical applicability assessment of a novel measure of bladder outlet resistance, aiming to enhance the diagnostic performance of uroflowmetry
AbstractBackgroundCurrently, the diagnostic ability of uroflowmetry, the most widely used urodynamic test available for initial assessment of patients with lower urinary tract symptoms (LUTS), is considered limited by its inability to accurately discriminate between the underlying mechanisms of this condition. To improve the diagnostic accuracy of uroflow, we developed a mathematical formula that calculates the flow resistive forces index (QRF), a novel measure of bladder outflow/urethral resistance, and assessed its clinical applicability compared to the maximum flow rate (Qmax).Materials and MethodsA cross ‐sectional o...
Source: LUTS: Lower Urinary Tract Symptoms - January 29, 2020 Category: Urology & Nephrology Authors: Evangelos Spyropoulos, Ioannis Galanakis, Dimitrios Deligiannis, Aikaterini Spyropoulou, Dimitrios Kotsiris, Aggelos Panagopoulos, Stamatios Mavrikos Tags: ORIGINAL ARTICLE Source Type: research

Self ‐perception of symptoms, medical help seeking, and self‐help strategies of women with interstitial cystitis/painful bladder syndrome
This study aims to investigate the self ‐perception of symptoms, medical help seeking, and self‐help strategies of women with interstitial cystitis (IC).MethodsA mixed method of qualitative and quantitative approaches was employed. The qualitative approach used in ‐depth interviews about the subjective experience of symptoms, medical help seeking, and self‐help strategies for their IC. The quantitative inquiry was conducted by a yes or no response to the question “Did self‐perceived severe symptoms of IC interfere with your daily life?” A loglinear model was applied to investigate the associations bet...
Source: LUTS: Lower Urinary Tract Symptoms - January 21, 2020 Category: Urology & Nephrology Authors: Hui ‐Chun Chen, Chieh‐Yu Liu, Chun‐Hou Liao, Lee‐Ing Tsao Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 12, Issue 1, Page 1-1, January 2020. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 9, 2020 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

How long does the effect of botulinum toxin in neurogenic patients last? An analysis of the subset of “good responders”
ConclusionThe results of our study indicate that the application of BoNT ‐A seems to be an effective and durable treatment in a large number of neurogenic patients after more than 10 years of follow‐up. However, botulinum toxin tolerance occurred in approximately 25% of patients. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 18, 2019 Category: Urology & Nephrology Authors: In ès Dominique, Benjamin Tremblais, Kathleen Charvier, Maria C. S. Nogueira, Philippe Paparel, Nicolas Morel Journel, Alain Ruffion Tags: ORIGINAL ARTICLE Source Type: research

Predictive factors for persistence of preoperative overactive bladder symptoms after transvaginal mesh surgery in women with pelvic organ prolapse
ConclusionTransvaginal mesh surgery eliminates overactive bladder symptoms in about two ‐thirds of pelvic organ prolapse patients. The preoperative International Prostate Symptom Score storage subscore was the most useful predictive factor for the persistence of preoperative overactive bladder symptoms after surgery. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 13, 2019 Category: Urology & Nephrology Authors: Atsushi Otsuka, Kyohei Watanabe, Yuto Matsushita, Hiromitsu Watanabe, Keita Tamura, Daisuke Motoyama, Toshiki Ito, Takayuki Sugiyama, Hideaki Miyake Tags: ORIGINAL ARTICLE Source Type: research

Increased bladder sensation without detrusor overactivity revisited: Use of a five ‐grade sensory measure
AbstractAimsIncreased bladder sensation (IBS) without detrusor overactivity (DO) is still a matter of debate, regarding its clinical relevance, urodynamic nature, underlying pathology, and management. Among these, we present our data focusing on the urodynamic nature of IBS without DO, by applying our five ‐grade sensory measure during urodynamics.MethodsWe enrolled 400 individuals who visited our laboratory for screening of lower urinary tract function, mostly with neurogenic etiologies. They included 74 control, 87 DO (irrespective of IBS), and 239 IBS (defined as first sensation
Source: LUTS: Lower Urinary Tract Symptoms - December 12, 2019 Category: Urology & Nephrology Authors: Fuyuki Tateno, Ryuji Sakakibara, Yosuke Aiba, Osamu Takahashi, Ayami Shimizu, Takeshi Oki Tags: ORIGINAL ARTICLE Source Type: research

Transurethral resection in women with symptomatic keratinizing squamous metaplasia of urinary bladder: A retrospective study of 92 cases
AbstractObjectivesTo investigate the efficacy of transurethral resection (TUR) on relieving urinary symptoms in patients with keratinizing squamous metaplasia (KSM) of the urinary bladder.MethodsData were analyzed from a retrospective study of patients receiving transurethral bipolar plasma resection (bi ‐TUR) treatment for symptomatic KSM. Urinary symptoms were assessed by the International Prostate Symptom Score (IPSS) and a numeric rating scale pain score. Efficacy was assessed using the IPSS to determine changes from baseline in lower urinary tract symptoms (LUTS). Self‐reported quality of l ife (QoL) was assessed ...
Source: LUTS: Lower Urinary Tract Symptoms - November 23, 2019 Category: Urology & Nephrology Authors: Huan Wang, Tie Chong, Xiu ‐Ying Tang, Wen‐Bo Zheng Tags: ORIGINAL ARTICLE Source Type: research

Effects of combined treatment with fesoterodine and mirabegron in a pelvic congestion rat model: Results from in vitro and in vivo functional studies
ConclusionsThe combination of 5 ‐hydroxymethyl tolterodine with mirabegron suggests the potential of synergistic effects in a rat pelvic congestion model. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 21, 2019 Category: Urology & Nephrology Authors: Kimio Sugaya, Hidetomi Yamagami, Saori Nishijima, Katsumi Kadekawa, Masanori Hizue, Yoshihiko Ito, Shizuo Yamada Tags: ORIGINAL ARTICLE Source Type: research

Phase I study of KRP ‐116D, a 50% w/w dimethyl sulfoxide aqueous solution, on the systemic absorption from bladder by intravesical instillation in healthy Japanese subjects
AbstractObjectiveThis was a single ‐institution, single‐dose, single‐arm phase 1 study in healthy adult males to evaluate the safety and absorption of dimethyl sulfoxide (DMSO) from the bladder into the body when KRP‐116D (a 50% w/w DMSO solution) was intravesically administered and allowed to remain in the bladder for 15 m inutes.MethodsSix healthy adult males were enrolled in this study. KRP ‐116D (50 mL) was instilled directly into the bladder via a catheter where it was allowed to remain for 15 minutes under lidocaine anesthesia in accordance with the usage of RIMSO‐50 (50% w/w DMSO sol...
Source: LUTS: Lower Urinary Tract Symptoms - November 5, 2019 Category: Urology & Nephrology Authors: Hideyo Shimada, Makoto Yono, Yuya Hojo, Yuka Hamamura, Atsushi Ootsuki Tags: ORIGINAL ARTICLE Source Type: research

Surgical results in women with detrusor underactivity and stress urinary incontinence undergoing suburethral sling procedure —Predictive factors for successful outcome
ConclusionsFor women with SUI and coexistent DU who underwent suburethral sling procedure, low IIQ ‐7 (≤6) scores and higher Qmax (≥6 mL/s) are predictors for improvement of surgical outcome. A Qmax of
Source: LUTS: Lower Urinary Tract Symptoms - November 4, 2019 Category: Urology & Nephrology Authors: Ching ‐Jung Chen, Soon‐Chin Yeoh, Hsin‐Tzu Yeh, Sheng‐Mou Hsiao, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Long ‐standing nonulcerative bladder pain syndrome: Impact of Thiele massage on bladder and sexual domains
AbstractPurpose: To assess the efficacy of Thiele massage (TM) as monotherapy for nonulcerative interstitial cystitis/bladder pain syndrome (IC/BPS).Methods: A prospective evaluation of 40 women with IC/BPS who underwent TM was conducted. TM was initially administrated by a physiotherapist and then self ‐administrated at home twice weekly for 16 weeks. Patients were assessed every 4 weeks on an outpatient basis. Assessment tools included 3‐day voiding diaries, the Likert visual analog scale (VAS) for pain, and the Interstitial Cystitis Symptom Index (ICSI) and the Interstitial Cystitis Prob lem Index (ICP...
Source: LUTS: Lower Urinary Tract Symptoms - October 23, 2019 Category: Urology & Nephrology Authors: Ahmed S. El ‐Hefnawy, Hanan Mohamed Mohamed Soliman, Shaimaa Omar Mohamed Abd‐Elbary, Wafaa Ismail Shereif Tags: ORIGINAL ARTICLE Source Type: research

Relationship between frailty and lower urinary tract symptoms among community ‐dwelling adults
ConclusionsIndividuals with LUTS are potentially frailer than those without LUTS. Although the influence of frailty on LUTS is different depending on the measurement tool, attention for frailty is necessary for subjects with LUTS. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - October 22, 2019 Category: Urology & Nephrology Authors: Osamu Soma, Shingo Hatakeyama, Atsushi Imai, Teppei Matsumoto, Itsuto Hamano, Naoki Fujita, Hiromichi Iwamura, Teppei Okamoto, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Shigeyuki Nakaji, Chikara O Tags: ORIGINAL ARTICLE Source Type: research

Effects of low ‐frequency intravaginal electrical stimulation on female urinary incontinence, quality of life, and urinary symptoms: A pilot study
This study investigated the effects of a low ‐frequency home‐based incontinence therapy device on quality of life (QoL) and urinary symptoms in women with urinary incontinence. From May 2017 to February 2018, 34 patients, aged ≥ 20 years, with involuntary urine leakage>2 times/week, were recruited to this study. Patients with severe pelvic organ prolapse, pregnancy, virgin status, and psychological problems were excluded. The incontinence home ‐care device treatments were administered in 12‐minute sessions, twice daily for 8 weeks. Simultaneously, hyperthermic conditions of 35°C to 40...
Source: LUTS: Lower Urinary Tract Symptoms - October 8, 2019 Category: Urology & Nephrology Authors: Sangrak Bae, Kyu Won Lee, Hyun Cheol Jeong, Bong Hee Park, Woong Jin Bae, Yong Seok Lee, Chang Hee Han, Sung Hak Kang, Sae Woong Kim Tags: ORIGINAL ARTICLE Source Type: research

A matched ‐pair analysis of patients with medium‐sized prostates (50 cc) treated for male LUTS with HoLEP or TURP
AbstractObjectivesTo evaluate perioperative parameters, early functional outcomes, and the safety profile in a matched ‐pair analysis of lower urinary tract symptom (LUTS) patients treated with holmium laser enucleation of the prostate (HoLEP) or transurethral resection of the prostate (TURP).MethodsWe conducted a retrospective, matched ‐pair analysis of 2011 men treated for LUTS in our institution from 2013 to 2017. In the final analysis, 197 patients (HoLEP n = 97; TURP n = 98) were matched for prostate size (50 cc), age, and body mass index, and both cohorts were compared for demographic parameters, clinical ...
Source: LUTS: Lower Urinary Tract Symptoms - September 30, 2019 Category: Urology & Nephrology Authors: Giuseppe Magistro, Thilo Westhofen, Christian G. Stief, Philipp Weinhold Tags: ORIGINAL ARTICLE Source Type: research

Cardiovascular safety of antimuscarinic add ‐on therapy in patients with overactive bladder who had a suboptimal response to mirabegron monotherapy: A post hoc analysis from the Japanese MILAI II study
ConclusionA favorable CV safety profile was observed following long ‐term combination treatment with mirabegron and an antimuscarinic in patients with OAB symptoms. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 29, 2019 Category: Urology & Nephrology Authors: Takao Katoh, Yasuhiko Igawa, Osamu Yamaguchi, Daisuke Kato, Takuya Hamada, Kentaro Kuroishi Tags: ORIGINAL ARTICLE Source Type: research

Association between the neutrophil ‐to‐lymphocyte ratio and intravesical prostatic protrusion in men with benign prostatic hyperplasia
AbstractObjectiveTo analyze the association between neutrophil ‐to‐lymphocyte ratio (NLR) and intravesical prostatic protrusion (IPP) in men with benign prostatic hyperplasia.MethodsTwo hundred and fifty men aged>50  years who presented with lower urinary tract symptoms at our institution between 2014 and 2018 were analyzed. Pearson's method was used for analysis of the correlation between NLR and IPP. Multivariate logistic regression analysis was used to identify predictors of IPP. Further analysis according to total prostate volume (TPV) was performed.ResultsThe NLR correlated positively with IPP (Pearson's r = 0.459,P
Source: LUTS: Lower Urinary Tract Symptoms - September 14, 2019 Category: Urology & Nephrology Authors: Mun Su Chung, Yun Jung Yang, Seung Hwan Lee, Byung Il Yoon Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 175-175, September 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 10, 2019 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Hyperlipidemia as a risk factor for discontinuation of prescribed antimuscarinics among geriatric overactive bladder patients
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 255-256, September 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 10, 2019 Category: Urology & Nephrology Authors: Yu ‐Chen Chen, Hao‐Wei Chen, Yung‐Shun Juan Tags: LETTER TO THE EDITOR Source Type: research

High incidence of lower urinary tract dysfunction in women with recurrent urinary tract infections
AbstractThe aim of this study was to evaluate lower urinary tract dysfunction (LUTD) in women with recurrent urinary tract infections (UTIs). One hundred consecutive female patients with recurrent UTIs who underwent videourodynamic study (VUDS) were included. Another 25 women free from recurrent UTIs served as controls. All the underlying diseases, urine analysis and culture results, VUDS findings, and treatment outcomes of voiding dysfunction were carefully reviewed and analyzed. The mean age of the recurrent UTIs patients was 64.0 ± 16.0 years. Storage and voiding dysfunctions were found in 90 (90%) patient...
Source: LUTS: Lower Urinary Tract Symptoms - August 28, 2019 Category: Urology & Nephrology Authors: Ping ‐Jui Lee, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Association of midline prostatic cysts and lower urinary tract symptoms: A case ‐control analysis of 606 transrectal ultrasound findings
ConclusionsThe presence of MPCs is not an independent factor for moderate to severe LUTS, and the size of the MPCs does not have any correlation to LUTS scores either. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 28, 2019 Category: Urology & Nephrology Authors: Bumsoo Park, Sung ‐Ho Ju, Seol Ho Choo Tags: ORIGINAL ARTICLE Source Type: research

Influence of alpha ‐adrenoceptor antagonists therapy on stool form in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia
ConclusionsThis study suggests that silodosin was associated with increased digestive symptoms such as diarrhea and loose stools. Therefore, oral drugs for BPH need to be selected by taking into consideration the possibility of digestive symptoms including both the state and type of stools. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 28, 2019 Category: Urology & Nephrology Authors: Seiji Matsumoto, Sachiko Kasamo, Kazumi Hashizume Tags: ORIGINAL ARTICLE Source Type: research

Cognitive burden and polypharmacy in elderly Japanese patients treated with anticholinergics for an overactive bladder
This study aimed to investigate the cognitive burden and polypharmacy in elderly patients treated with anticholinergics for an overactive bladder. We conducted a retrospective study of patients with an overactive bladder receiving treatment at two hospitals in Japan (Nara Medical University Hospital and Saiseikai Nara Hospital). Prescription data were collected from the medical records of the patients registered between January 2013 and April 2014. The Anticholinergic Cognitive Burden Scale was used to estimate the severity of the anticholinergic effects on the cognition of each patient. We collected the prescription data ...
Source: LUTS: Lower Urinary Tract Symptoms - August 27, 2019 Category: Urology & Nephrology Authors: Takako Shiota, Kazumasa Torimoto, Masahiro Okuda, Ryo Iwata, Hiromi Kumamoto, Makito Miyake, Akihide Hirayama, Nobumichi Tanaka, Kiyohide Fujimoto Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of the effect of a new method on the pelvic organ prolapse symptoms
ConclusionThis new method of postural or positional inversion leads to a greater improvement in symptoms of pelvic organ prolapse. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 25, 2019 Category: Urology & Nephrology Authors: Zahra Gorji, Abbas A. Pourmomeny, Maryam Hajhashemy Tags: ORIGINAL ARTICLE Source Type: research

Predictive factors for recovery of voiding function after transurethral prostate surgery in men with small prostate volume and very low detrusor contractility
This study aims to investigate effectiveness and predictors of voiding function recovery after prostate surgery in patients with DU.MethodsMale patients with DU and small total prostate volume (TPV,
Source: LUTS: Lower Urinary Tract Symptoms - August 19, 2019 Category: Urology & Nephrology Authors: Shu ‐Yu Wu, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Further characterization of a novel EP2 and EP3 receptor dual agonist, ONO ‐8055, on lower urinary tract function in normal and lumbar canal stenosis rats
ConclusionsThis agonist did not augment bladder contractility or urethral relaxation in normal rats. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 19, 2019 Category: Urology & Nephrology Authors: Noritoshi Sekido, Jun Kida, Takeya Otsuki, Hiroko Mashimo, Hidekazu Matsuya, Hiroki Okada Tags: ORIGINAL ARTICLE Source Type: research

Efficacy of Tadalafil Therapy and Changes in Oxidative Stress Levels in Male Patients with Lower Urinary Tract Symptoms and Overactive Bladder
The objective findings were assessed using uroflowmetry. Oxidative stress was assessed by determining urinary levels of 8‐hydroxy‐2′‐deoxyguanosine (8‐OHdG) levels with an adjustment for urinary creatinine (CR) concentration.ResultsAfter tadalafil administration, total and individual indices of the OABSS assessment showed significant improvement. In addition, total storage and voiding symptoms that contributed to the IPSS were also significantly improved. The voided volume was increased, and the maximum flow rate was improved after tadalafil treatment (P = .002 and
Source: LUTS: Lower Urinary Tract Symptoms - August 12, 2019 Category: Urology & Nephrology Authors: Tomohiro Matsuo, Yasuyoshi Miyata, Kyohei Araki, Yuta Mukae, Asato Otsubo, Kojiro Ohba, Hideki Sakai Tags: ORIGINAL ARTICLE Source Type: research

The autologous pubovaginal fascial sling: An update in 2019
AbstractThe contemporary management of stress urinary incontinence (SUI) has seen renewed interest in the use of autologous fascia for the formation of a retropubic suburethral sling. Traditionally, it has been used in only the most severe of incontinence cases, such as those women with intrinsic sphincter deficiency, or in patients requiring concomitant reconstructive procedures. In the current climate surrounding transvaginal mesh, many doctors and patients are shying away from the less morbid synthetic midurethral sling. International literature has demonstrated that the fascial sling is a safe and efficacious procedure...
Source: LUTS: Lower Urinary Tract Symptoms - August 12, 2019 Category: Urology & Nephrology Authors: Sophie Plagakis, Vincent Tse Tags: REVIEW ARTICLE Source Type: research

Efficacy and safety of 25 and 50 μg desmopressin orally disintegrating tablets in Japanese patients with nocturia due to nocturnal polyuria: Results from two phase 3 studies of a multicenter randomized double‐blind placebo‐controlled parallel‐group development program
This study assessed the efficacy and safety of desmopressin orally disintegrating tablets (ODTs) in Japanese males (50 and 25  μg) and females (25 μg) with nocturia due to nocturnal polyuria (NP). Two Phase 3 randomized double‐blind placebo‐controlled studies of 342 males and 190 females with nocturia due to NP were conducted. The primary endpoint was change from baseline in mean number of nocturnal voids. In add ition, time to first awakening to void, nocturnal urine volume, NP index (NPI), and quality of life were assessed during a 12‐week treatment period. In males, 50 and 25 μg desmo...
Source: LUTS: Lower Urinary Tract Symptoms - August 8, 2019 Category: Urology & Nephrology Authors: Osamu Yamaguchi, Kristian V. Juul, Ali Falahati, Toru Yoshimura, Futoshi Imura, Mikiya Kitamura Tags: ORIGINAL ARTICLE Source Type: research

Mirabegron causes vesical and urethral relaxation in rats with spinal cord injury
AbstractThe effects of solifenacin and mirabegron on vesical and urethral function were compared in rats with or without spinal cord injury (SCI). Isovolumetric cystometry and urethral pressure recording were initially performed in intact rats. Then, the bladder neck was ligated under urethane anesthesia, after which a catheter was inserted through the bladder dome for isovolumetric cystometry and another catheter was inserted into the urethra to measure urethral pressure. Solifenacin (0.03 –3 mg/kg) or mirabegron (0.03–3 mg/kg) was injected intravenously, and bladder and urethral activity were recorded. To cre...
Source: LUTS: Lower Urinary Tract Symptoms - August 6, 2019 Category: Urology & Nephrology Authors: Kimio Sugaya, Saori Nishijima, Katsumi Kadekawa, Katsuhiko Noguchi, Tomoyuki Ueda, Hideyuki Yamamoto Tags: ORIGINAL ARTICLE Source Type: research

Prevalence, potential risk factors, and symptomatic bother of lower urinary tract symptoms during and after pregnancy
ConclusionsLUTS were much more prevalent during than after pregnancy, with nocturia and frequency being the most prevalent. Moderate or severe bother was more common during pregnancy than after pregnancy. CS was associated with a decreased prevalence both of storage and voiding LUTS after delivery. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - July 17, 2019 Category: Urology & Nephrology Authors: Zhiyi Li, Tao Xu, Lei Zhang, Lan Zhu Tags: ORIGINAL ARTICLE Source Type: research

Validation of a real ‐time bladder sensation meter during oral hydration in healthy adults: Repeatability and effects of fill rate and ultrasound probe pressure
ConclusionsThis study demonstrated repeatability of real ‐time bladder sensation during a two‐fill oral hydration protocol with ultrasound. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - July 11, 2019 Category: Urology & Nephrology Authors: Derek Sheen, Hiren Kolli, Anna S. Nagle, Zachary Cullingsworth, Naomi N. Vinod, Hameeda A. Naimi, Stefan G. De Wachter, Suzanne E. Mazzeo, Lynn Stothers, John E. Speich, Adam P. Klausner Tags: ORIGINAL ARTICLE Source Type: research

Underactive bladder in aging rats is associated with a reduced number of serotonin ‐expressing cells in the urethra and is improved by serotonin application to the urethra
AbstractThe aim of this study was to determine whether aging ‐related detrusor underactivity (DU) involves a decrease in 5‐hydroxytryptamine (5‐HT‐positive)‐expressing urethral cells and whether 5‐HT stimulation of urethral sensory fibers improves detrusor function. Cystometries were performed in young (6 months) and aged (18–24 months) female Wistar rats. Aged rats with voiding contractions (VC) that were 2SD below the mean of those in young rats were considered to have DU. Bladder voiding efficiency (BVE) was calculated during saline or 5‐HT solution cystometries. Rats were perfusion‐fixed wi...
Source: LUTS: Lower Urinary Tract Symptoms - June 27, 2019 Category: Urology & Nephrology Authors: Ana Coelho, Ana Charrua, Raquel Oliveira, Helena Cavaleiro, C élia D. Cruz, Francisco Cruz Tags: ORIGINAL ARTICLE Source Type: research

Administration of human umbilical cord blood mononuclear cells restores bladder dysfunction in streptozotocin ‐induced diabetic rats
This study evaluated the effect of human umbilical cord blood mononuclear cells (HUCB ‐MNCs) on bladder dysfunction in streptozotocin (STZ; 35 mg/kg, i.v.)‐induced diabetic rats.MethodsAdult male Sprague –Dawley rats (n = 30) were equally divided into three groups: control group, STZ‐diabetic group, and HUCB‐MNC‐treated group (1 × 106 cells). HUCB ‐MNCs were isolated by density gradient centrifugation from eight healthy donors and injected into the corpus cavenosum in STZ‐diabetic rats 4 weeks after the induction of diabetes. Studies were performed 4 weeks after ...
Source: LUTS: Lower Urinary Tract Symptoms - June 16, 2019 Category: Urology & Nephrology Authors: Ecem Kaya ‐Sezginer, Didem Yilmaz‐Oral, Serap Gur Tags: ORIGINAL ARTICLE Source Type: research

Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats
This study investigated the effects of tadalafil on the urethra and detrusor in the initial phase of diabetes in rats.MethodsThirty ‐six female Sprague‐Dawley rats were assigned to a non‐diabetes (ND), diabetes (D), or tadalafil‐treated diabetes (DT) group (n = 12 per group), with the DT group receiving oral tadalafil (2 mg/kg/d) for 7 days before the experiments. Seven weeks after diabetes induction (by a single intra peritoneal injection of streptozotocin), urethral and intravesical pressure were simultaneously recorded in vivo, whereas responses of detrusor strips to potassium chloride (30 mM), ele...
Source: LUTS: Lower Urinary Tract Symptoms - June 16, 2019 Category: Urology & Nephrology Authors: Daisuke Gotoh, Kazumasa Torimoto, Hirotaka Iwasaki, Takashi Iwamoto, Yosuke Morizawa, Shunta Hori, Makito Miyake, Nobumichi Tanaka, Akihide Hirayama, Eiichiro Nishi, Kiyohide Fujimoto Tags: ORIGINAL ARTICLE Source Type: research

Substitution urethroplasty for the treatment of male urethral stricture: Outcomes in an Australian center
ConclusionsSubstitution urethroplasty has a high success rate, durable response, and high patient satisfaction. Standardization of surveillance protocol after urethroplasty is recommended. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 6, 2019 Category: Urology & Nephrology Authors: Yasser Al ‐Hakeem, Amanda Chung, Belinda Chung, Vincent Tse Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 3, Page 87-90, May 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 23, 2019 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Is trigonitis a neglected, imprecise, misunderstood, or forgotten diagnosis?
AbstractTo consolidate our understanding of “trigonitis” and its relevance in current urologic practice, we reviewed the literature on this entity. The MEDLINE, EMBASE, and Cochrane databases (1905 to present) were systematically reviewed for any English language articles addressing the following terms: trigonitis, cystitis trigoni, cysti tis cystica, squamous metaplasia, pseudomembranous trigonitis, vaginal metaplasia, infection or inflammation of the trigone, and trigonitis in recurrent urinary tract infections (rUTI). Abstracts or articles not focused on trigonitis, or those only repeating findings from othe...
Source: LUTS: Lower Urinary Tract Symptoms - April 14, 2019 Category: Urology & Nephrology Authors: Zhina Sadeghi, Gregory MacLennan, Stacy J. Childs, Philippe E. Zimmern Tags: REVIEW ARTICLE Source Type: research

Effect of ureteral stent diameter on ureteral stent ‐related symptoms
ConclusionThis is the first study to show that larger ‐diameter ureteral stents induce significantly worse urinary symptoms. Ureteral stents with smaller diameters are recommended to improve ureteral stent‐related symptoms. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 6, 2019 Category: Urology & Nephrology Authors: Makoto Taguchi, Kenji Yoshida, Motohiko Sugi, Hidefumi Kinoshita, Tadashi Matsuda Tags: ORIGINAL ARTICLE Source Type: research

Development and validation of the International Consultation on Incontinence Modular Questionnaire for Male Lower Urinary Tract Symptoms (ICIQ ‐MLUTS) and the ICIQ‐MLUTS Long Form in Chinese population
ObjectiveThe aim of this study was to develop and validate Chinese versions of the International Consultation on Incontinence Modular Questionnaire for Male Lower Urinary Tract Symptoms (ICIQ ‐MLUTS) and ICIQ‐MLUTS Long Form (LF), and to discuss their potential functions.MethodsThe original ICIQ ‐MLUTS and ICIQ‐MLUTS LF were translated into Chinese after obtaining permission from the International Consultation on Incontinence Modular Questionnaire Advisory Board. Between November 2017 and August 2018, the Chinese versions of the ICIQ‐MLUTS and ICIQ‐MLUTS LF were validated by adminis tering them to male patients...
Source: LUTS: Lower Urinary Tract Symptoms - April 2, 2019 Category: Urology & Nephrology Authors: Weina Huang, Qiang Wang, Jiawei Chen, Peng Wu Tags: ORIGINAL ARTICLE Source Type: research