Effect of 2% Topical Lidocaine Gel on Discomfort from Electrical Stimulation During Nerve Conduction Studies- A Prospective Double-Blind Placebo-Controlled Study
CONCLUSION: The results indicate that topical lidocaine 2% gel reduces discomfort associated with NCS. However, despite the statistical significance, clear clinical significance may be lacking. Clinical implementation may be considered for the subgroups that showed the greatest benefit. Further studies that incorporate more efficient drug delivery methods may yield better results.PMID:37791113 | PMC:PMC10543085 | DOI:10.2147/LRA.S426076 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - October 4, 2023 Category: Anesthesiology Authors: Kefah Al-Hayk Mahmoud M Smadi Lina M Elsalem Ahmed Yassin Suha Aqaileh Deema H Obiedat Ahmad Kefah Al-Hayk Majdi Al Qawasmeh Raid Kofahi Khalid El-Salem Source Type: research
Systemic Ropivacaine Concentrations Following Local Infiltration Analgesia and Femoral Nerve Block in Older Patients Undergoing Total Knee Arthroplasty
CONCLUSION: Administration of a fixed 225 mg dose of ropivacaine for local infiltration analgesia with epinephrine and femoral nerve block results in plasma ropivacaine concentrations below the toxicity threshold, indicating their safety. The use of local infiltration analgesia with epinephrine provides a greater safety margin, as local infiltration analgesia without epinephrine may lead to ropivacaine concentrations associated with symptoms of local anesthetic toxicity.PMID:37731601 | PMC:PMC10508276 | DOI:10.2147/LRA.S425353 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - September 21, 2023 Category: Anesthesiology Authors: Sigita Kazune Inga Nurka Matiss Zolmanis Arturs Paulausks Dace Bandere Source Type: research
