Serum Testosterone and Non ‐alcoholic Fatty Liver Disease in Men and Women in the US
ConclusionsIn this nationally representative sample of adults in the US, low total testosterone levels were associated with suspected NAFLD in men and postmenopausal women independent of known risk factors.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - March 1, 2018 Category: Gastroenterology Authors: Jeong Yoon Yim, Jinju Kim, Donghee Kim, Aijaz Ahmed Tags: Original Article Source Type: research
Unanticipated Increases in Hepatic Steatosis among HIV Patients Receiving MR Antagonist Eplerenone for NAFLD
ConclusionsThe unexpected observation of increased hepatic steatosis with administration of eplerenone led to early termination of the investigation. While limited due to the small number of participants and the open‐label design, the present study provides data to suggest that mineralocorticoid receptor antagonism with eplerenone may not be an effective approach to treat hepatic steatosis in HIV or the general population. Additional research is needed to determine the pathophysiologic mechanism behind these unanticipated observations.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - March 1, 2018 Category: Gastroenterology Authors: Chloe S. Chaudhury, Julia B. Purdy, Chia ‐Ying Liu, Caryn G. Morse, Takara L. Stanley, David Kleiner, Colleen Hadigan Tags: Brief Definitive Report Source Type: research
Analysis of genotyping for predicting liver injury marker, Procollagen III in persons at risk of non ‐alcoholic fatty liver disease
ConclusionsGenotyping therefore has limited value for predicting severe liver disease in at‐risk individuals identified in a community setting.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - March 1, 2018 Category: Gastroenterology Authors: Jane I. Grove, Prarthana Thiagarajan, Stuart Astbury, Rebecca Harris, Toby Delahooke, I. Neil Guha, Guruprasad P Aithal Tags: Original Article Source Type: research
Reproducibility of EASL criteria and modified RECIST in patients treated with sorafenib
ConclusionsThe reproducibility of the EASLc and mRECIST in assessing treatment outcomes was high in patients with advanced HCC treated with sorafenib.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - March 1, 2018 Category: Gastroenterology Authors: Mi Young Jeon, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang ‐Hyub Han, Song‐Ee Baek, Hye Soo Kim, Seung Up Kim, Mi Suk Park Tags: Original Article Source Type: research
Validation of the Baveno VI and the expanded Baveno VI criteria to identify patients who could avoid screening endoscopy
ConclusionsIn this Asian cohort study, the Baveno VI criteria was able to identify who could safely avoid screening endoscopy. The expanded Baveno VI criteria could spare more endoscopies but also could increase the odds of missing a HRV.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - March 1, 2018 Category: Gastroenterology Authors: Joohwan Bae, Dong Hyun Sinn, Wonseok Kang, Geum ‐Youn Gwak, Moon Seok Choi, Yong‐Han Paik, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik Tags: Original Article Source Type: research
Identification of Recombinant Strains in HCV Genotype 1 and 3: Is it needed?
This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - February 26, 2018 Category: Gastroenterology Authors: Jaba Zarkua, Mamuka Zakalashvili, Robert G. Gish, David Metreveli Tags: Letter to the Editor Source Type: research
Osteoporosis in chronic liver disease
This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - February 26, 2018 Category: Gastroenterology Authors: N úria Guañabens, Albert Parés Tags: Reviews Source Type: research
Hepatitis C virus direct ‐acting antivirals therapy impacts on extracellular vesicles microRNAs content and on their immunomodulating properties
Liver International, EarlyView. (Source: Liver International)
Source: Liver International - February 24, 2018 Category: Gastroenterology Source Type: research
Acute kidney injury, but not sepsis, is associated with higher procedure ‐related bleeding in patients with decompensated cirrhosis
Liver International, EarlyView. (Source: Liver International)
Source: Liver International - February 24, 2018 Category: Gastroenterology Source Type: research
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Liver International, Ahead of Print. (Source: Liver International)
Source: Liver International - February 24, 2018 Category: Gastroenterology Source Type: research
Hepatitis C virus direct ‐acting antivirals therapy impacts on extracellular vesicles microRNAs content and on their immunomodulating properties
ConclusionsEnrichment of immunomodulatory microRNAs in exosomes of HCV patients was correlated with their inhibitory activity on innate immune cells function. Direct‐acting antivirals (DAA) treatment was observed to revert both microRNA content and functional profiles of systemic exosomes towards those of healthy donors. Exosome‐associated microRNAs may provide valuable biomarkers to monitor immune response recovery. (Source: Liver International)
Source: Liver International - February 24, 2018 Category: Gastroenterology Authors: Laura Santangelo, Veronica Bordoni, Claudia Montaldo, Eleonora Cimini, Alessandra Zingoni, Cecilia Battistelli, Gianpiero D'Offizi, Maria R. Capobianchi, Angela Santoni, Marco Tripodi, Chiara Agrati Tags: ORIGINAL ARTICLE Source Type: research
Low molecular weight heparin does not increase bleeding and mortality post endoscopic variceal band ligation in cirrhotic patients
ConclusionsLMWH does not increase the risk of post‐procedural bleeding and does not affect survival of cirrhotic patients undergoing prophylactic EVL.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - February 22, 2018 Category: Gastroenterology Authors: Marcello Bianchini, Giulia Cavani, Ambra Bonaccorso, Laura Turco, Francesco Vizzutti, Alessandro Sartini, Stefano Gitto, Alberto Merighi, Federico Banchelli, Erica Villa, Filippo Schepis Tags: Original Article Source Type: research
Improvement of hepatic fibrosis and patient ‐reported outcomes in non‐alcoholic steatohepatitis treated with selonsertib
Liver International, EarlyView. (Source: Liver International)
Source: Liver International - February 22, 2018 Category: Gastroenterology Source Type: research
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Liver International, Ahead of Print. (Source: Liver International)
Source: Liver International - February 22, 2018 Category: Gastroenterology Source Type: research
