LDLR gene rearrangements in Czech FH patients likely arise from one mutational event
Large deletions and duplications within the low-density lipoprotein receptor (LDLR) gene make up approximately 10% of LDLR pathogenic variants found in Czech patients with familial hypercholesterolemia. The goal ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 2, 2024 Category: Lipidology Authors: Kate řina Konečná, Petra Zapletalová, Tomáš Freiberger and Lukáš Tichý Tags: Hypothesis Source Type: research
Reprogramming of lipid metabolism in the tumor microenvironment: a strategy for tumor immunotherapy
Lipid metabolism in cancer cells has garnered increasing attention in recent decades. Cancer cells thrive in hypoxic conditions, nutrient deficiency, and oxidative stress and cannot be separated from alteratio... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 1, 2024 Category: Lipidology Authors: Yuting Wu, Xi Pu, Xu Wang and Min Xu Tags: Review Source Type: research
Predicting the 10-year incidence of dyslipidemia based on novel anthropometric indices, using data mining
The aim was to establish a 10-year dyslipidemia incidence model, investigating novel anthropometric indices using exploratory regression and data mining. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 31, 2024 Category: Lipidology Authors: Alireza Takhttavous, Maryam Saberi-Karimian, Somayeh Ghiasi Hafezi, Habibollah Esmaily, Marzieh Hosseini, Gordon A. Ferns, Elham Amirfakhrian, Mark Ghamsary, Majid Ghayour-Mobarhan and Maryam Alinezhad-Namaghi Tags: Research Source Type: research
Association of hysterectomy with nonalcoholic fatty liver disease among US women
This study thus sought to further probe the association of hysterectomy with NAFLD. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 31, 2024 Category: Lipidology Authors: Shuanghong Jin, Shaoxun Li, Peipei Fang, Chenwei Pan and Shanshan Huang Tags: Research Source Type: research
Association of saturated fatty acids with cancer risk: a systematic review and meta-analysis
Extensive research has explored the link between saturated fatty acids (SFAs) and cardiovascular diseases, alongside other biological dysfunctions. Yet, their association with cancer risk remains a topic of de... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 30, 2024 Category: Lipidology Authors: Jin Mei, Meiyu Qian, Yanting Hou, Maodi Liang, Yao Chen, Cuizhe Wang and Jun Zhang Tags: Review Source Type: research
Correlations between genetically predicted lipid-lowering drug targets and inflammatory bowel disease
Millions of individuals globally suffer from Inflammatory bowel diseases (IBDs). There is a dearth of large population-based investigations on lipid metabolism and IBDs, and it is unclear whether lipid-lowerin... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 29, 2024 Category: Lipidology Authors: Kuiyuan Huang, Shenan Huang and Ming Xiong Tags: Research Source Type: research
Differences between repeated lipid profile measurements in a tertiary hospital over a short time period
Measurement of the plasma lipid profile, mainly low-density lipoprotein cholesterol (LDL-C), is widely used in the management of hospitalized patients as part of their cardiometabolic risk assessment. In commo... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 27, 2024 Category: Lipidology Authors: Or Porat, Marriele Kaplan, Smadar Atlibenkin, Dalia Hasson-Gilad, Amir Karban and Ronen Zalts Tags: Research Source Type: research
Triglyceride-glucose index is a risk factor for breast cancer in China: a cross-sectional study
This research delved into the association between the risk of the Chinese population suffering from breast cancer (BC) and the triglyceride-glucose (TyG) index. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 26, 2024 Category: Lipidology Authors: Jinghua Zhang, Binbin Yin, Ya Xi and Yongying Bai Tags: Research Source Type: research
Yam Gruel alone and in combination with metformin regulates hepatic lipid metabolism disorders in a diabetic rat model by activating the AMPK/ACC/CPT-1 pathway
As independent and correctable risk factors, disturbances in lipid metabolism are significantly associated with type 2 diabetes mellitus (T2DM). This research investigated the mechanism underlying the lipid-re... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 25, 2024 Category: Lipidology Authors: Yanling Dai, Chen Qiu, Diandian Zhang, Mianli Li and Weinan Liu Tags: Research Source Type: research
Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study
The association between lipid and bone metabolism, particularly the role of high-density lipoprotein cholesterol (HDL-C) in regulating bone mineral density (BMD), is of significant interest. Despite numerous s... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 24, 2024 Category: Lipidology Authors: Yongbing Sun, Xin Qi, Xuan Wang, Xinbei Lin, Yang Zhou, Yawei Du, Ao Liu, Xue Lv, Jing Zhou, Zhonglin Li, Xiaoling Wu, Zhi Zou, Michael Zhang, Jiadong Zhu, Feifei Shang, Yongli Li & hellip; Tags: Research Source Type: research
Machine learning-based integration identifies the ferroptosis hub genes in nonalcoholic steatohepatitis
Ferroptosis, is characterized by lipid peroxidation of fatty acids in the presence of iron ions, which leads to cell apoptosis. This leads to the disruption of metabolic pathways, ultimately resulting in liver... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 23, 2024 Category: Lipidology Authors: Longfei Dai, Wenkang Yuan, Renao Jiang, Zhicheng Zhan, Liangliang Zhang, Xinjian Xu, Yuyang Qian, Wenqi Yang and Zhen Zhang Tags: Research Source Type: research
Residual risk of cardiovascular complications in statin-using patients with type 2 diabetes: the Taiwan Diabetes Registry Study
This study was conducted to identify factors associated with these residual risks in patien... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 23, 2024 Category: Lipidology Authors: Chin-Sung Kuo, Nai-Rong Kuo, Yun-Kai Yeh, Yau-Jiunn Lee, Lee-Ming Chuang, Hua-Fen Chen, Ching-Chu Chen, Chun-Chuan Lee, Chih-Cheng Hsu, Hung-Yuan Li, Horng-Yih Ou and Chii-Min Hwu Tags: Research Source Type: research
Dietary patterns derived by reduced rank regression are associated with lipid disorders among Korean adults: a cross-sectional analysis
Lipid disorders are a potent risk factor for cardiovascular diseases. Moreover, the intake of dietary fatty acids has been closely related to blood lipid levels. Therefore, this cross-sectional study examined ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 23, 2024 Category: Lipidology Authors: Hyun Ah Kim, Hye Ran Shin and SuJin Song Tags: Research Source Type: research
Adipokines in atopic dermatitis: the link between obesity and atopic dermatitis
Atopic dermatitis (AD) is a chronic skin condition with intense pruritus, eczema, and dry skin. The recurrent intense pruritus and numerous complications in patients with AD can profoundly affect their quality... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 23, 2024 Category: Lipidology Authors: Shiyun Zhang, Bingjie Zhang, Yuehua Liu and Li Li Tags: Review Source Type: research
A novel lipid metabolism-based risk model associated with immunosuppressive mechanisms in diffuse large B-cell lymphoma
The molecular diversity exhibited by diffuse large B-cell lymphoma (DLBCL) is a significant obstacle facing current precision therapies. However, scoring using the International Prognostic Index (IPI) is inade... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - January 22, 2024 Category: Lipidology Authors: Zhaoli Zhang, Chong Zhao, Shaoxin Yang, Wei Lu and Jun Shi Tags: Research Source Type: research
