Pathogenic sphingosine 1-phosphate pathway in psoriasis: a critical review of its pathogenic significance and potential as a therapeutic target
Sphingosine-1-phosphate (S1P) is a sphingolipid mediator that exerts a variety of biological functions, including immune, cardiovascular, and neurological regulation as well as tumor promotion, through high-af... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 18, 2023 Category: Lipidology Authors: Yuechun Zhao, Yuheng Zhang, Jiaqi Li, Ningxin Zhang, Qiubai Jin, Yuxia Qi and Ping Song Tags: Review Source Type: research

The association between the body roundness index and the risk of colorectal cancer: a cross-sectional study
Colorectal cancer (CRC), has a link between obesity, especially visceral fat. The body roundness index (BRI) can more accurately assess body fat and visceral fat levels. It is, however, unknown whether BRI is ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 18, 2023 Category: Lipidology Authors: Wenxing Gao, Lujia Jin, Dingchang Li, Yue Zhang, Wen Zhao, Yingjie Zhao, Jingwang Gao, Lin Zhou, Peng Chen and Guanglong Dong Tags: Research Source Type: research

Leucine supplementation in maternal high-fat diet alleviated adiposity and glucose intolerance of adult mice offspring fed a postweaning high-fat diet
Combined maternal and postnatal high-fat (HF) diet intake predisposes offspring to metabolic dysregulation during adulthood. As the inhibitory effects of leucine consumption on obesity and metabolic disorders ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 15, 2023 Category: Lipidology Authors: Juhae Kim, Juyoung Kim and Young Hye Kwon Tags: Research Source Type: research

Excessive exogenous cholesterol activating intestinal LXR α-ABCA1/G5/G8 signaling pathway can not reverse atherosclerosis in ApoE−/− mice
The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce cardiovascular and cerebrovascular diseases. However, the influence and relevance of exogen... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 15, 2023 Category: Lipidology Authors: Xichao Yu, Xue Ding, Han Feng, Yunhui Bi, Yu Li, Jinjun Shan and Huimin Bian Tags: Research Source Type: research

In vitro, in vivo, and in silico analysis of synbiotics as preventive interventions for lipid metabolism in ethanol-induced adipose tissue injury
The risk of alcoholic liver disease (ALD) is increased by excessive ethanol drinking. For the prevention of ALD, the effects of ethanol on the liver, adipose tissue, and gut are crucial. Interestingly, garlic ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 13, 2023 Category: Lipidology Authors: Dhara Patel, Pooja Rathaur, Kirti Parwani, Farhin Patel, Dixa Sharma, Kaid Johar and Palash Mandal Tags: Research Source Type: research