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Identification of new phosphorylation sites of CD23 in B-cells of patients with chronic lymphocytic leukemia
(Source: Leukemia Research)
Source: Leukemia Research - May 9, 2018 Category: Hematology Authors: Martina Ma ďarová, Rastislav Mucha, Stanislav Hresko, Zuzana Makarová, Zuzana Gdovinová, Jarmila Szilasiová, Marianna Vitková, Tomáš Guman, Natalia Štecová, Tomas Dobransky Tags: Research paper Source Type: research

The division of chronic myelomonocytic leukemia (cmml)-1 into cmml-0 and cmml-1 according to 2016 world health organization (who) classification has no impact in outcome in a large series of patients from the spanish group of mds
(Source: Leukemia Research)
Source: Leukemia Research - May 9, 2018 Category: Hematology Authors: Blanca Xicoy, Ana Triguero, Esperanza Such, Olga Garc ía, María-José Jiménez, Montserrat Arnán, Teresa Bernal, Marina Diaz-Beya, David Valcárcel, Carme Pedro, Fernando Ramos, María-Luz Amigo, Rosa Collado, Laura Palomo, María-Teresa Ardanaz, Marí Tags: Letter to the Editor Source Type: research

Optimal Use of Novel Agents in Chronic Lymphocytic Leukemia
(Source: Leukemia Research)
Source: Leukemia Research - May 7, 2018 Category: Hematology Authors: Mitchell R. Smith, Robert F. Weiss Source Type: research

High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ na ïve lymphocytes and prevents TTV reactivation
(Source: Leukemia Research)
Source: Leukemia Research - May 2, 2018 Category: Hematology Authors: Lorenzo Iovino, Francesco Mazziotta, Giovanni Carulli, Francesca Guerrini, Riccardo Morganti, Valentina Mazzotti, Fabrizio Maggi, Lisa Macera, Enrico Orciuolo, Gabriele Buda, Edoardo Benedetti, Francesco Caracciolo, Sara Galimberti, Mauro Pistello, Mario Tags: Meeting report Source Type: research

Shifting of Erythroleukemia to Myelodysplastic Syndrome according to the Revised WHO classification: Biologic and Cytogenetic features of Shifted Erythroleukemia
(Source: Leukemia Research)
Source: Leukemia Research - April 28, 2018 Category: Hematology Authors: Sohee Ryu, Hee Sue Park, Sung-Min Kim, Kyongok Im, Jung-Ah Kim, Sang Mee Hwang, Sung-Soo Yoon, Dong Soon Lee Source Type: research

Corrigendum to ’CD41 immune staining of micromegakaryocytes improves the diagnosis of myelodysplastic syndrome and differentiation from pancytopenia’ [leukemia research. 2018; 66: 15-19]
The authors regret that Lifang Huang and Miao Zheng contributed equally to this work and should be considered as co-first authors. (Source: Leukemia Research)
Source: Leukemia Research - April 26, 2018 Category: Hematology Authors: Jinjin Huang, Zhiqiong Wang, Lifang Huang, Miao Zheng Source Type: research

Editorial Board
(Source: Leukemia Research)
Source: Leukemia Research - April 26, 2018 Category: Hematology Source Type: research

Elevated miR-20b-5p expression in peripheral blood mononuclear cells: a novel, independent molecular biomarker of favorable prognosis in chronic lymphocytic leukemia
(Source: Leukemia Research)
Source: Leukemia Research - April 26, 2018 Category: Hematology Authors: Sotirios G. Papageorgiou, Christos K. Kontos, Panagiotis Tsiakanikas, Georgia Stavroulaki, Anthi Bouchla, Diamantina Vasilatou, Efthymia Bazani, Afroditi Lazarakou, Andreas Scorilas, Vasiliki Pappa Tags: Research paper Source Type: research

Phenotype variability of patients with post polycythemia vera and post essential thrombocythemia myelofibrosis is associated with the time to progression from polycythemia vera and essential thrombocythemia
(Source: Leukemia Research)
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Barbara Mora, Toni Giorgino, Paola Guglielmelli, Elisa Rumi, Margherita Maffioli, Alessandro Rambaldi, Marianna Caramella, Rami Komrokji, Jason Gotlib, Jean Jacques Kiladjian, Francisco Cervantes, Timothy Devos, Francesca Palandri, Valerio De Stefano, Mar Tags: Letter to the Editor Source Type: research

High Dose Daunorubicin: New standard of care for FLT3 ITD mutant AML
(Source: Leukemia Research)
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Eunice S. Wang, Kristen O ’Dwyer Tags: Commentary Source Type: research

Phenotype variability of patients with post polycythemia vera and post essential thrombocythemia myelofibrosis is associated with the time to progression from polycythemia vera and essential thrombocythemia
(Source: Leukemia Research)
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Barbara Mora, Toni Giorgino, Paola Guglielmelli, Elisa Rumi, Margherita Maffioli, Alessandro Rambaldi, Marianna Caramella, Rami Komrokji, Jason Gotlib, Jean Jacques Kiladjian, Francisco Cervantes, Timothy Devos, Francesca Palandri, Valerio De Stefano, Mar Tags: Letter to the Editor Source Type: research

Monitoring of clonal evolution of double C-KIT exon 17 mutations by Droplet Digital PCR in patients with core-binding factor acute myeloid leukemia
(Source: Leukemia Research)
Source: Leukemia Research - April 22, 2018 Category: Hematology Authors: Yanhong Tan, Zhuang Liu, Wenjun Wang, Guiyang Zhu, Jianli Guo, Xiuhua Chen, Chaofeng Zheng, Zhifang Xu, Jianmei Chang, Fanggang Ren, Hongwei Wang Tags: Research paper Source Type: research

Chinese and Europeans with Acute Myeloid Leukemia Have Discordant Mutation Topographies
(Source: Leukemia Research)
Source: Leukemia Research - April 21, 2018 Category: Hematology Authors: Min Zhang, Jiawei Yin, Qinghua He, Fan Zhang, Hongyu Huang, Biao Wu, Xuedong Wang, Hong Liu, Hongchao Yin, Yan Zeng, Robert Peter Gale, Depei Wu, Bin Yin Source Type: research

Associations of myeloid hematological diseases of the elderly with Osteoporosis: A longitudinal analysis of routine health care data
(Source: Leukemia Research)
Source: Leukemia Research - April 20, 2018 Category: Hematology Authors: Thomas Datzmann, Freya Trautmann, Falko Tesch, Anna Mies, Lorenz C. Hofbauer, Uwe Platzbecker, Jochen Schmitt Tags: Research paper Source Type: research

Cell membrane-bound CD200 signals both via an extracellular domain and following nuclear translocation of a cytoplasmic fragment
(Source: Leukemia Research)
Source: Leukemia Research - April 18, 2018 Category: Hematology Authors: Zhiqi Chen, Andras Kapus, Ismat Khatri, Olha Kos, Fang Zhu, Reginald M. Gorczynski Tags: Research paper Source Type: research

Corrigendum to ’CD41 immune staining of micromegakaryocytes improves the diagnosis of myelodysplastic syndrome and differentiation from pancytopenia’ [leukemia research. 2018; 66: 15-19]
The authors regret that Lifang Huang and Miao Zheng contributed equally to this work and should be considered as co-first authors. (Source: Leukemia Research)
Source: Leukemia Research - April 17, 2018 Category: Hematology Authors: Jinjin Huang, Zhiqiong Wang, Lifang Huang, Miao Zheng Source Type: research

Editorial Board
(Source: Leukemia Research)
Source: Leukemia Research - April 17, 2018 Category: Hematology Source Type: research

The Rising Prevalence of Chronic Myeloid Leukemia in France
(Source: Leukemia Research)
Source: Leukemia Research - April 17, 2018 Category: Hematology Authors: Marc Delord, St éphanie Foulon, Jean-Michel Cayuela, Philippe Rousselot, Julia Bonastre Tags: Research paper Source Type: research

Effect of absolute monocyte count post-transplant on the outcome of patients with acute myeloid leukemia undergoing myeloablative allogeneic hematopoietic stem cell transplant with busulfan and cyclophosphamide conditioning
(Source: Leukemia Research)
Source: Leukemia Research - April 11, 2018 Category: Hematology Authors: Liyuan Tang, Na Wang, Chongyun Xing, Qiang Zhuang, Bin Liang, Lan Sun, Yi Chen, Yan Qian, Zhijian Shen, Songfu Jiang, Kang Yu, Jianhua Feng Tags: Research paper Source Type: research

Inter-observer variance and the need for standardization in the morphological classification of myelodysplastic syndrome
(Source: Leukemia Research)
Source: Leukemia Research - April 9, 2018 Category: Hematology Authors: Keiko Sasada, Noriko Yamamoto, Hiroki Masuda, Yoko Tanaka, Ayako Ishihara, Yasushi Takamatsu, Yutaka Yatomi, Waichiro Katsuda, Issei Sato, Hirotaka Matsui, on behalf of the Kyushu regional department of the Japanese Society of Laboratory Hematology Tags: Research paper Source Type: research

Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway
(Source: Leukemia Research)
Source: Leukemia Research - April 5, 2018 Category: Hematology Authors: Theresa Grohmann, Melanie Penke, Stefanie Petzold-Quinque, Susanne Schuster, Sandy Richter, Wieland Kiess, Antje Garten Source Type: research

New rapid method to detect BCR-ABL fusion genes with multiplex RT-qPCR in one-tube at a time
(Source: Leukemia Research)
Source: Leukemia Research - April 4, 2018 Category: Hematology Authors: Yong-Qing Tong, Zhi-Jun Zhao, Bei Liu, An-Yu Bao, Hong-Yun Zheng, Jian Gu, Ying Xia, Mary McGrath, Sinisa Dovat, Chunhua Song, Yan Li Tags: Research paper Source Type: research

Which donor is better when a matched donor is not available domestically? Comparison of outcomes of allogeneic stem cell transplantation with haploidentical and international donors in a homogenous ethnic population
(Source: Leukemia Research)
Source: Leukemia Research - April 3, 2018 Category: Hematology Authors: Hyunkyung Park, Yoo Jin Lee, Sang-Jin Shin, Jayoun Lee, Silvia Park, Inho Kim, Joon-ho Moon, Hyewon Lee, Jun Ho Jang, Sung-Soo Yoon, Youngil Koh Source Type: research

Prognostic factors for thrombosis-free survival and overall survival in polycythemia vera: A retrospective analysis Of 623 PTS With long follow-up
(Source: Leukemia Research)
Source: Leukemia Research - March 31, 2018 Category: Hematology Authors: Ambra Di Veroli, Francesco Buccisano, Alessandro Andriani, Marco Montanaro, Roberto Latagliata, Cristina Santoro, Massimo Breccia, Francesca Spirito, Michele Cedrone, Barbara Anaclerico, Sabrina Leonetti Crescenzi, Raffaele Porrini, Marianna De Muro, Gius Tags: Letter to the Editor Source Type: research

Secreted Wnt antagonists in Leukemia: A road yet to be paved
(Source: Leukemia Research)
Source: Leukemia Research - March 28, 2018 Category: Hematology Authors: Melek Pehlivan, Ceyda Çalışkan, Zeynep Yüce, Hakki Ogun Sercan Source Type: research

Reactive oxygen species activate differentiation gene transcription of acute myeloid leukemia cells via the JNK/c-JUN signaling pathway
Acute myeloid leukemia (AML) is a hematological malignancy that mainly originates from the bone marrow, with affected cells displaying myeloid characteristics. AML cells fail to undergo terminal differentiation and remain immature and proliferative. Process of terminal differentiation could be blocked by deregulation of transcription factors, such as RUNX1 and PU.1 (encoded by SPI-1 gene), that control myeloid differentiation. Mutations or reduced expression of these transcription factors were able to potentiate the development of AML [1,2]. (Source: Leukemia Research)
Source: Leukemia Research - March 27, 2018 Category: Hematology Authors: Chung Fan Lam, Hoi Ting Yeung, Yuk Man Lam, Ray Kit Ng Tags: Research paper Source Type: research

Reactive Oxygen Species Activate Differentiation Gene Transcription of Acute Myeloid Leukemia Cells via the JNK/c-JUN Signaling Pathway
(Source: Leukemia Research)
Source: Leukemia Research - March 27, 2018 Category: Hematology Authors: Chung Fan Lam, Hoi Ting Yeung, Yuk Man Lam, Ray Kit Ng Tags: Research paper Source Type: research

Clinico-Hematological Profile and Thrombotic/Hemorrhagic Events in 150 Chinese Patients with Essential Thrombocythemia
(Source: Leukemia Research)
Source: Leukemia Research - March 27, 2018 Category: Hematology Authors: Dian Zhou, Wei Chen, Hai Cheng, Jian-lin Qiao, Li-li Zhu, Zhen-yu Li, Kai-lin Xu Tags: Research paper Source Type: research

Lifetime physical inactivity is associated with increased risk for Hodgkin and non-Hodgkin lymphoma: A case-control study
(Source: Leukemia Research)
Source: Leukemia Research - March 27, 2018 Category: Hematology Authors: John Lewis Etter, Rikki Cannioto, Kah Teong Soh, Emad Alquassim, Hani Almohanna, Zachary Dunbar, Janine M. Joseph, Sophia Balderman, Francisco Hernandez-Ilizaliturri, Kirsten B. Moysich Source Type: research

Lenalidomide Treatment in Lower Risk Myelodysplastic Syndromes – the experience of a Czech hematology center. (Positive effect of erythropoietin ± prednisone addition to lenalidomide in refractory or relapsed patients)
(Source: Leukemia Research)
Source: Leukemia Research - March 27, 2018 Category: Hematology Authors: Anna Jonasova, Radana Neuwirtova, Helena Polackova, Magda Siskova, Tomas Stopka, Eduard Cmunt, Monika Belickova, Alena Moudra, Lubomir Minarik, Ota Fuchs, Kyra Michalova, Zuzana Zemanova Tags: Research paper Source Type: research

Corrigendum to: Comparison of Induction Therapy in Non-high Risk Acute Promyelocytic Leukemia with Arsenic Trioxide or in Combination with ATRA Leukemia Research 66 (2018) 85 –88
Regarding the survival results, please note that the 2.5-year disease free survival and overall survival in ATO group were 60% and 86% respectively and in ATO plus ATRA group, both disease-free survival and overall survival were 100%. (Source: Leukemia Research)
Source: Leukemia Research - March 20, 2018 Category: Hematology Authors: Ardeshir Ghavamzadeh, Mahdi Jalili, Sharbanoo Rostami, Marjan Yaghmaie, Leyla Sharifi Aliabadi, Seyed Asadollah Mousavi, Mohammad Vaezi, Hossein Kamranzadeh Fumani, Mohammad Jahani, Kamran Alimoghaddam Source Type: research

Editorial Board
(Source: Leukemia Research)
Source: Leukemia Research - March 20, 2018 Category: Hematology Source Type: research

High frequency of dicentric chromosomes detected by multi-centromeric FISH in patients with acute myeloid leukemia and complex karyotype
A complex karyotype (CK) is found in the bone marrow cells of 10 –12% of patients with acute myeloid leukemia (AML) at the initial cytogenetic evaluation [1]. The incidence increases with the age of the patient [1,2]. CK has been variably defined as harboring at least five abnormalities in different studies [3–6]. CK is traditionally regarded as a poor progno stic factor, and it is strongly associated with poor outcomes particularly in patients showing more than five changes in bone marrow cells [7,8]. (Source: Leukemia Research)
Source: Leukemia Research - March 19, 2018 Category: Hematology Authors: Iveta Sarova, Jana Brezinova, Zuzana Zemanova, Sarka Ransdorfova, Karla Svobodova, Silvia Izakova, Lenka Pavlistova, Libuse Lizcova, Adela Berkova, Karolina Skipalova, Lucie Hodanova, Cyril Salek, Anna Jonasova, Kyra Michalova Tags: Research paper Source Type: research

Comparison of intensive, pediatric-inspired therapy with non-intensive therapy in older adults aged 55 –65 years with Philadelphia chromosome-negative acute lymphoblastic leukemia
The results of the treatment of Philadelphia chromosome (Ph)-negative acute lymphoblastic leukemia (ALL) in adults have improved in recent years [1]. The use of pediatric-like protocols in the younger adult (YA) population partially explains this improvement. Intensified pediatric-inspired regimens with continuous dose-intense exposure to chemotherapy and higher cumulative doses of non-myelotoxic drugs such as L-asparaginase and glucocorticoids are currently used by most groups to treat ALL in adult patients [2,3]. (Source: Leukemia Research)
Source: Leukemia Research - March 19, 2018 Category: Hematology Authors: Josep-Maria Ribera, Olga Garc ía, Cristina Gil, Santiago Mercadal, Irene García-Cadenas, Pau Montesinos, Pere Barba, Susana Vives, José González-Campos, Mar Tormo, Jordi Esteve, Aurelio López, María José Moreno, Jordi Ribera, Natalia Alonso, Aranch Tags: Research paper Source Type: research

High frequency of dicentric chromosomes detected by multi-centromeric FISH in patients with acute myeloid leukemia and complex karyotype
(Source: Leukemia Research)
Source: Leukemia Research - March 19, 2018 Category: Hematology Authors: Iveta Sarova, Jana Brezinova, Zuzana Zemanova, Sarka Ransdorfova, Karla Svobodova, Silvia Izakova, Lenka Pavlistova, Libuse Lizcova, Adela Berkova, Karolina Skipalova, Lucie Hodanova, Cyril Salek, Anna Jonasova, Kyra Michalova Tags: Research paper Source Type: research

Comparison of intensive, pediatric-inspired therapy with non-intensive therapy in older adults aged 55-65 years with Philadelphia chromosome-negative acute lymphoblastic leukemia
(Source: Leukemia Research)
Source: Leukemia Research - March 19, 2018 Category: Hematology Authors: Josep-Maria Ribera, Olga Garc ía, Cristina Gil, Santiago Mercadal, Irene García-Cadenas, Pau Montesinos, Pere Barba, Susana Vives, José González-Campos, Mar Tormo, Jordi Esteve, Aurelio López, María José Moreno, Jordi Ribera, Natalia Alonso, Aranch Tags: Research paper Source Type: research

Lenalidomide plus dexamethasone for patients with relapsed or refractory multiple myeloma: Final results of a non-interventional study and comparison with the pivotal phase 3 clinical trials
Multiple myeloma (MM) is one of the most common hematological malignancies. It newly affects approximately 21,500 patients (pts) each year in Europe with 15,000 dying from this disease annually [1]. Although, the currently used first-line therapies induce remissions in the majority of pts, relapses are expected to occur in almost all. (Source: Leukemia Research)
Source: Leukemia Research - March 14, 2018 Category: Hematology Authors: Wolfgang Knauf, Ali Aldaoud, Christoph Losem, Johann Mittermueller, Michael Neise, Beate Niemeier, Johanna Harde, Tanja Trarbach, Karin Potthoff Tags: Research paper Source Type: research

Lenalidomide plus dexamethasone for patients with relapsed or refractory multiple myeloma: Final results of a non-interventional study and comparison with the pivotal phase 3 clinical trials
(Source: Leukemia Research)
Source: Leukemia Research - March 14, 2018 Category: Hematology Authors: Wolfgang Knauf, Ali Aldaoud, Christoph Losem, Johann Mittermueller, Michael Neise, Beate Niemeier, Johanna Harde, Tanja Trarbach, Karin Potthoff Tags: Research paper Source Type: research

Safety and efficacy of the CD95-ligand inhibitor asunercept in transfusion-dependent patients with low and intermediate risk MDS
Myelodysplastic syndromes (MDS) are a group of heterogeneous oligoclonal stem cell disorders characterized by peripheral cytopenia and a risk of transformation into acute myeloid leukemia (AML). Anemia is the most frequent symptom and reflects the impaired erythroid cell maturation. (Source: Leukemia Research)
Source: Leukemia Research - March 10, 2018 Category: Hematology Authors: Tobias Boch, Thomas Luft, Georgia Metzgeroth, Maximilian Mossner, Johann-Christoph Jann, Daniel Nowak, Franziska La Meir, Christiane Schumann, Jennifer Klemmer, Susanne Brendel, Harald Fricke, Claudia Kunz, Christel Wei ß, Wolf-Karsten Hofmann, Florian N Tags: Research paper Source Type: research

Safety and Efficacy of the CD95 - Ligand Inhibitor Asunercept in Transfusion - Dependent Patients with Low and Intermediate Risk MDS
(Source: Leukemia Research)
Source: Leukemia Research - March 10, 2018 Category: Hematology Authors: Tobias Boch, Thomas Luft, Georgia Metzgeroth, Maximilian Mossner, Johann-Christoph Jann, Daniel Nowak, Franziska La Meir, Christiane Schumann, Jennifer Klemmer, Susanne Brendel, Harald Fricke, Claudia Kunz, Christel Wei ß, Wolf-Karsten Hofmann, Florian N Tags: Research paper Source Type: research

Similar incidence of typhlitis in patients receiving various doses of daunorubicin or idarubicin as induction for acute myeloid leukemia
Acute myeloid leukemia (AML) is the most common adult acute leukemia with 21,380 estimated new cases and 10,590 estimated deaths in 2017 [1]. For newly diagnosed AML patients, less than 60 years old, induction chemotherapy with infusional standard-dose cytarabine for 7  days plus an anthracycline (either idarubicin or daunorubicin) for 3 days is a National Comprehensive Cancer Network (NCCN) category 1 recommendation and is the standard of care for the last 30 years [2]. Memorial Sloan Kettering Cancer Center uses either idarubicin (IDA) or daunorubicin for th e treatment of AML, the doses of daunorubicin are either 60...
Source: Leukemia Research - March 8, 2018 Category: Hematology Authors: Amanda N. Seddon, Joshua Chaim, Oguz Akin, Esther Drill, Angela G. Michael, Nelly Adel, Martin S. Tallman Tags: Research paper Source Type: research

Comparison of anthracyclines used for induction chemotherapy in patients with FLT3-ITD-mutated acute myeloid leukemia
FMS-like tyrosine kinase 3 (FLT3) gene mutations are found in approximately 30% of newly diagnosed acute myeloid leukemia (AML) patients; internal tandem duplication (ITD) mutations in the juxtamembrane domain of FLT3 account for two-thirds of FLT3 mutations. Patients with FLT3-ITD mutations have a poor prognosis, with shorter remission duration and higher relapse rates than FLT3 wild-type AML patients. Although several tyrosine kinase inhibitors (TKIs) targeting FLT3 improve clinical outcomes of FLT3-ITD-mutated AML, the median survival time of these patients is approximately 1  year. (Source: Leukemia Research)
Source: Leukemia Research - March 8, 2018 Category: Hematology Authors: Eun-Ji Choi, Je-Hwan Lee, Jung-Hee Lee, Han-Seung Park, Sun-Hye Ko, Eun-Hye Hur, Juhyun Moon, Bon-Kwan Goo, Yeonhee Kim, Miee Seol, Young-Shin Lee, Young-Ah Kang, Mijin Jeon, Ji Min Woo, Kyoo-Hyung Lee Tags: Research paper Source Type: research

Similar incidence of typhlitis in patients receiving various doses of daunorubicin or idarubicin as induction for acute myeloid leukemia
(Source: Leukemia Research)
Source: Leukemia Research - March 8, 2018 Category: Hematology Authors: Amanda N. Seddon, Joshua Chaim, Oguz Akin, Esther Drill, Angela G. Michael, Nelly Adel, Martin S. Tallman Tags: Research paper Source Type: research

Comparison of anthracyclines used for induction chemotherapy in patients with FLT3-ITD-mutated acute myeloid leukemia
(Source: Leukemia Research)
Source: Leukemia Research - March 8, 2018 Category: Hematology Authors: Eun-Ji Choi, Je-Hwan Lee, Jung-Hee Lee, Han-Seung Park, Sun-Hye Ko, Eun-Hye Hur, Juhyun Moon, Bon-Kwan Goo, Yeonhee Kim, Miee Seol, Young-Shin Lee, Young-Ah Kang, Mijin Jeon, Ji Min Woo, Kyoo-Hyung Lee Tags: Research paper Source Type: research

Acute myeloid leukemia induction with cladribine: Outcomes by age and leukemia risk
Successful acute myeloid leukemia (AML) induction chemotherapy reduces leukemic cells, restores normal hematopoiesis, and results in complete remission (CR) [1], which is associated with improved prognosis [2,3]. Many induction strategies exist, but for over 40 years the cytarabine/anthracycline regimen has been considered standard (so-called 7  + 3) [4]. The best outcomes occur in younger patients with adequate performance status and favorable risk leukemia. In contrast, older patients (≥60 years) and those with adverse prognostic markers fare poorly [5]. (Source: Leukemia Research)
Source: Leukemia Research - March 6, 2018 Category: Hematology Authors: Martin W. Schoen, Susan K. Woelich, James T. Braun, Dhinesh V. Reddy, Mark J. Fesler, Paul J. Petruska, Carl E. Freter, Jack M. Lionberger Tags: Research paper Source Type: research

Acute Myeloid Leukemia Induction with Cladribine: Outcomes by Age and Leukemia Risk
(Source: Leukemia Research)
Source: Leukemia Research - March 6, 2018 Category: Hematology Authors: Martin W. Schoen, Susan K. Woelich, James T. Braun, Dhinesh V. Reddy, Mark J. Fesler, Paul J. Petruska, Carl E. Freter, Jack M. Lionberger Tags: Research paper Source Type: research