Wogonin protects against cisplatin-induced acute kidney injury by targeting RIPK1-mediated necroptosis
en Lv & Jun Li (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Xiao-Ming Meng Hai-Di Li Wei-Feng Wu Patrick Ming-Kuen Tang Gui-Ling Ren Li Gao Xiao-Feng Li Yang Yang Tao Xu Tao-Tao Ma Zeng Li Cheng Huang Lei Zhang Xiong-Wen Lv Jun Li Source Type: research

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation
& Jun Li (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Xiao-Ming Meng Gui-Ling Ren Li Gao Qin Yang Hai-Di Li Wei-Feng Wu Cheng Huang Lei Zhang Xiong-wen Lv Jun Li Source Type: research

Neutrophils: a cornerstone of liver ischemia and reperfusion injury
eixeira (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Thiago Henrique Caldeira de Oliveira Pedro Elias Marques Paul Proost Mauro Martins M Teixeira Source Type: research

Immune checkpoint inhibitors in sarcomas: in quest of predictive biomarkers
Bovée (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Robin Veenstra Marie Kostine Anne-Marie Cleton-Jansen Noel FCC de Miranda Judith VMG Bov é e Source Type: research

Experimental models of pancreatic cancer desmoplasia
Senapati (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Sujit Suklabaidya Pujarini Dash Biswajit Das Voddu Suresh Prakash K Sasmal Shantibhusan Senapati Source Type: research

Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer
p; Peter W Hamilton (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Peter Bankhead Jos é A Fern á ndez Darragh G McArt David P Boyle Gerald Li Maurice B Loughrey Gareth W Irwin D Paul Harkin Jacqueline A James Stephen McQuaid Manuel Salto-Tellez Peter W Hamilton Source Type: research

Cholecystectomy as a risk factor of metabolic syndrome: from epidemiologic clues to biochemical mechanisms
u Tian (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Yongsheng Chen Shuodong Wu Yu Tian Source Type: research

Cholecystectomy: a way forward and back to metabolic syndrome ?
Cholecystectomy: a way forward and back to metabolic syndrome? Laboratory Investigation 98, 4 (January 2018). doi:10.1038/labinvest.2017.129 Authors: Gabriella Garruti, David Q-H Wang, Agostino Di Ciaula & Piero Portincasa (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Authors: Gabriella Garruti David Q-H Wang Agostino Di Ciaula Piero Portincasa Source Type: research

Inside the USCAP Journals
Laboratory Investigation 98, 2 (January 2018). doi:10.1038/labinvest.2017.135 (Source: Laboratory Investigation)
Source: Laboratory Investigation - January 3, 2018 Category: Laboratory Medicine Source Type: research

High concordance of a closed-system, RT-qPCR breast cancer assay for HER2 mRNA, compared to clinically determined immunohistochemistry, fluorescence in situ hybridization, and quantitative immunofluorescence
; David L Rimm (Source: Laboratory Investigation)
Source: Laboratory Investigation - December 1, 2017 Category: Laboratory Medicine Authors: Brad E Wasserman Daniel E Carvajal-Hausdorf Kenneth Ho Wendy Wong Natalie Wu Victor C Chu Edwin W Lai Jodi M Weidler Michael Bates Veronique Neumeister David L Rimm Source Type: research

Lung tumor exome files with T-cell receptor recombinations: a mouse model of T-cell infiltrates reflecting mutation burdens
Blanck (Source: Laboratory Investigation)
Source: Laboratory Investigation - December 1, 2017 Category: Laboratory Medicine Authors: Yaping N Tu Wei Lue Tong Timothy J Fawcett George Blanck Source Type: research

Whole tumor section quantitative image analysis maximizes between-pathologists ’ reproducibility for clinical immunohistochemistry-based biomarkers
Whole tumor section quantitative image analysis maximizes between-pathologists’ reproducibility for clinical immunohistochemistry-based biomarkers Laboratory Investigation 97, 1508 (December 2017). doi:10.1038/labinvest.2017.82 Authors: Michael Barnes, Chukka Srinivas, Isaac Bai, Judith Frederick, Wendy Liu, Anindya Sarkar, Xiuzhong Wang, Yao Nie, Bryce Portier, Monesh Kapadia, Olcay Sertel, Elizabeth Little, Bikash Sabata & Jim Ranger-Moore (Source: Laboratory Investigation)
Source: Laboratory Investigation - December 1, 2017 Category: Laboratory Medicine Authors: Michael Barnes Chukka Srinivas Isaac Bai Judith Frederick Wendy Liu Anindya Sarkar Xiuzhong Wang Yao Nie Bryce Portier Monesh Kapadia Olcay Sertel Elizabeth Little Bikash Sabata Jim Ranger-Moore Source Type: research

A simple method based on Sanger sequencing and MS Word wildcard searching to identify Cas9-induced frameshift mutations
Shaohua Yao (Source: Laboratory Investigation)
Source: Laboratory Investigation - December 1, 2017 Category: Laboratory Medicine Authors: Hui Jie Zhuoling Li Ping Wang Linjie Zhao Qian Zhang Xiaomin Yao Xiangrong Song Yinglan Zhao Shaohua Yao Source Type: research

Expression, function, and regulation of the embryonic transcription factor TBX1 in parathyroid tumors
abrina Corbetta (Source: Laboratory Investigation)
Source: Laboratory Investigation - December 1, 2017 Category: Laboratory Medicine Authors: Chiara Verdelli Laura Avagliano Vito Guarnieri Filomena Cetani Stefano Ferrero Leonardo Vicentini Edoardo Beretta Alfredo Scillitani Pasquale Creo Gaetano Pietro Bulfamante Valentina Vaira Sabrina Corbetta Source Type: research

Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses
Gary H Perdew (Source: Laboratory Investigation)
Source: Laboratory Investigation - December 1, 2017 Category: Laboratory Medicine Authors: Gulsum E Muku Tejas S Lahoti Iain A Murray Michael A Podolsky Kayla J Smith Troy D Hubbard Guray Kuzu Krishne Gowda Shantu G Amin Gary H Perdew Source Type: research