Acute kidney injury and continuous renal replacement therapy in children; what pediatricians need to know.
Authors: Cho MH, Kang HG
Abstract
Acute kidney injury (AKI) is abrupt deterioration of renal function, and its diagnosis relies upon creatinine measurements and urine output. AKI is associated with higher morbidity and mortality, and is a risk factor of development of chronic kidney disease. There is no proven medication for AKI. Therefore prevention and early detection are important. Physicians need to be aware of the risk factors for AKI, and monitor renal function in high risk patients. AKI management includes optimization of volume status and renal perfusion, avoidance of nephrotoxic agents, and suffic...
Source: Korean Journal of Pediatrics - October 26, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Respiratory Syncytial Virus-Associated Seizures in Korean Children during 2011/01 -2016/12.
Conclusion: Although FS is the most common RSV-associated seizure, the proportion of complex FS was higher than that of general FS. Transient cytotoxic edema may be a pathogenic mechanism of RSV-related encephalopathy with seizure.
PMID: 30360041 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 26, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Diagnostic value of eosinopenia and neutrophil to lymphocyte ratio on early onset neonatal sepsis.
Conclusion: Eosinopenia has a high specificity value as a diagnostic marker of EONS and an increased in NLR has a high sensitivity and specificity value as a marker to diagnose EONS.
PMID: 30304894 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Understanding of type 1 diabetes mellitus: What we know and where we go.
Authors: Cheon CK
Abstract
The incidence of type 1 diabetes mellitus (T1DM) in children and adolescents is on the rise world-wide. T1DM is caused by the combined effects of genetic and environmental factors that makes it difficult to predict whether or not an individual will inherit disease. Due to the level of self-care necessary in the maintenance of T1DM, it is crucial for pediatric settings to support achieving optimal glucose control especially when adolescents are beginning to take more responsibility for their own health. Innovative insulin delivery system such as continuous subcutaneous insulin inf...
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Rapidly growing pediatric trampoline-related injuries in Korea: a 10-year single center retrospective study.
Conclusion: In Korea, the mechanism of trampoline injury is similar to that in indoor trampoline parks but is characterized by a smaller space and multi-users. The use of trampolines and injuries in children < 6 years old are increasing rapidly. Prohibiting the use of trampolines by children <6 years old, restricting simultaneous use by multiple children, and ensuring adult supervision should be strictly emphasized. Public awareness and policy guideline development are needed to reduce trampoline-related injuries.
PMID: 30304896 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Changes in the Thyroid Hormone Profiles in Children with Nephrotic Syndrome.
Conclusion: Thyroid hormone profile abnormal findings were observed in 51.6% of pediatric patients with NS. Thyroid hormone levels normalized after remission, regardless of levothyroxine therapy.
PMID: 30304897 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Lymphocyte-monocyte ratio at day 14 of first cisplatin-doxorubicin chemotherapy is associated with treatment outcome of pediatric patients with localized osteosarcoma.
Conclusion: In addition to pretreatment lymphocyte count, LMR during chemotherapy had prognostic significance in pediatric osteosarcoma patients. Further studies involving larger cohorts are necessary to validate our findings.
PMID: 30304898 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Dorsal midline cutaneous stigmata associated with occult spinal dysraphism in pediatric patients.
Conclusion: Our results suggest that adding other dorsal midline cutaneous stigmata, particularly fibrofatty masses, to a sacrococcygeal dimple is associated with OSD or cord tethering requiring surgery. Concurrent presence of other congenital anomalies should be considered a predictable condition for OSD.
PMID: 30304899 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Clinical features and prognostic factors of early-onset sepsis : a 7.5-year experience in one neonatal intensive care unit.
Conclusion: The common pathogens responsible for EOS in NICU patients are GBS and E. coli. Infection caused by Gram-negative bacteria, decreased activity in the early phase of infection, and neutropenia were associated with poor outcomes.
PMID: 30304900 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Genotype-Phenotype Correlations in Pediatric Patients with Myotonic Dystrophy Type 1.
Conclusions: Clinical variables exhibiting statistically significant differences between the subgroups should be the focus for prognosis and preparation of tailored management approaches for patients, and our findings will contribute to achieve this important goal for patients with DM1.
PMID: 30304901 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Current use of safety restraint systems and front seats in Korean children based on the 2008-2015 Korea National Health and Nutrition Examination Survey.
Conclusion: Although the rate of safety-restraint-system use for children is increasing annually, it remains low. Additionally, the use rate of front passenger seats for children is high. To reduce the rates of injury and death of children from traffic accidents, it is necessary to educate on the appropriate use of safety restraint systems according to age and body size and to develop stronger regulations.
PMID: 30304902 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Outcomes of transcatheter closure of ductus arteriosus in infants less than six months of age - A single-center experience.
Conclusion: A relatively higher incidence of major complications was observed in infants less than 6 months of age. The decision regarding treatment modality should be individualized.
PMID: 30304903 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years.
Authors: Kwak M, Yeh HR, Yum MS, Kim HJ, You SJ, Sung KT
Abstract
Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of 10 years. Interferon-alpha (IFN-α) is a protein that exerts its antiviral activity via enhancement of cellular immune response and is reported to be an effective drug for the treatment of SSPE. However, there is currently no consensus regarding the optimal duration of IFN-α therapy. Here, we present a case report of a pat...
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Non-alcoholic fatty liver disease in obese and non-obese pediatric patients.
Conclusions: Non-obese patients present a substantial proportion of pediatric NAFLD cases. Significant abnormal lipid concentrations were found in non-obese and abdominal obesity was important risk factor for non-obese NAFLD.
PMID: 30304905 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
The clinical characteristics and prognosis of subgaleal hemorrhage in newborn.
Conclusion: The morbidity rate was 41.2% due to severe metabolic acidosis. Anemia, hyperbilirubinemia, low Apgar scores, and subdural hemorrhage did not affect the prognosis. The long-term outcomes of neonates with SGH are generally good. Only arterial blood pH was significantly associated with death.
PMID: 30304906 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 13, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
