Diagnostic and prognostic value of proadrenomedullin in neonatal sepsis.
Conclusion: Pro-ADM can be used as a reliable biomarker for neonatal sepsis. High pro-ADM levels were associated with mortality and could be an early indicator of disease outcome.
PMID: 29853940 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 3, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Clinical implications in laboratory parameter values in acute Kawasaki disease for early diagnosis and proper treatment.
Conclusion: The severity of systemic inflammation in KD was reflected in the laboratory values including CRP, neutrophil differential, albumin, and hemoglobin. Observing changes in these laboratory parameters by repeated examinations prior to the peak of inflammation in acute KD may aid in diagnosis of early-presenting KD patients.
PMID: 29853941 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 3, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Differentiation between incomplete Kawasaki disease and secondary hemophagocytic lymphohistiocytosis following Kawasaki disease using N-terminal pro-brain natriuretic peptide.
Conclusion: The NT-proBNP level may be helpful in distinguishing incomplete KD from KD with HLH. The NT-proBNP level should be determined in KD patients with prolonged fever, in addition to the white blood cell count, platelet count, and ferritin level, to evaluate secondary HLH.
PMID: 29853942 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 3, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Epilepsy syndromes during the first year of life and the usefulness of an epilepsy gene panel.
Authors: Lee EH
Abstract
Recent advances in genetics have determined that a number of epilepsy syndromes that occur in the first year of life are associated with genetic etiologies. These syndromes range from benign familial epilepsy syndromes to early-onset epileptic encephalopathies that lead to poor prognoses and severe psychomotor retardation. An early genetic diagnosis can save time and overall cost by reducing the amount of time and resources expended to reach a diagnosis. Furthermore, a genetic diagnosis can provide accurate prognostic information and, in certain cases, enable targeted therapy. Here...
Source: Korean Journal of Pediatrics - May 2, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Sudden unexpected cardio-respiratory arrest after venipuncture in children.
Conclusion: Cardiorespiratory arrest after venipuncture is unpredictable and the probable cause of most cases is a vasovagal reaction. Medical personnel must be aware of the risk of unexpected cardiorespiratory arrest during routine intravenous procedures.
PMID: 29713356 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 2, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
TORCH (toxoplasmosis, rubella, cytomegalovirus, and herpes simplex virus) screening of small for gestational age and intrauterine growth restricted neonates: efficacy study in a single institute in Korea.
Conclusion: Considering the incidence and risk of TORCH in Korea, the financial burden of TORCH screening, and the single positive TORCH finding in our study, we suggest disease-specific screening based on maternal history and the clinical symptoms of the neonate. Regarding CMV, which may present asymptomatically, universal screening may be appropriate upon cost-benefit analysis.
PMID: 29713357 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 2, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
The association of total blood mercury levels and overweight among Korean adolescents: analysis of the Korean National Health and Nutrition Examination Survey (KNHANES) 2010-2013.
Conclusion: Our results suggest an association between total blood mercury levels and overweight in Korean adolescents.
PMID: 29713358 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 2, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Hypercalciuria and febrile convulsion in children under 5 years old.
Conclusion: Our results indicated that there is a statistical association between convulsion and hypercalciuria in children. Since we found this association with a cross-sectional assessment, further studies, especially prospective and controlled designs, are needed.
PMID: 29713359 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 2, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Intestinal duplication revealed by posterior reversible encephalopathy syndrome.
We report a unique case of intestinal duplication detected on posterior reversible encephalopathy syndrome (PRES) in a 13-year-old girl. She was admitted to the pediatric Emergency Department because of generalized seizures. Radiological assessment revealed a large, well-defined, thick-walled cystic lesion in the mid abdomen, suggestive of duplication cyst associated to a PRES. Exploration confirmed the diagnosis of ileal duplication cyst, and the mass was resected. The postoperative course was uneventful. Both hypertension and neurological dysfunction resolved after the mass resection. A followup brain magnetic resonance ...
Source: Korean Journal of Pediatrics - May 2, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Comparison of postnatal catch-up growth according to definitions of small for gestational age infants.
Conclusion: Despite different definitions, there were no significant differences between the two SGA groups in postnatal catch-up growth up to age 24 months, except for height at 6 months. Compared to infants with appropriate catch-up growth, low gestational age and BW were risk factors for failed catch-up growth at 6 months.
PMID: 29628966 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 11, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Augmentation of respiratory muscle activities in preterm infants with feeding desaturation.
Conclusion: This study showed that respiratory muscle activities were augmented during feeding in preterm infants compared to full-term infants. Additionally, respiratory muscle activities were inversely correlated with all clinical variables.
PMID: 29628967 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 11, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Clinical manifestation of Campylobacter enteritis in children.
Conclusion: Age (≥103.5 months) and higher CRP level (≥4.55 mg/dL) were good predictors of Campylobacter enterocolitis. If neither criterion was met, Campylobacter enterocolitis was unlikely (negative predictive value 97.2%). When both criteria were met, Campylobacter enterocolitis was highly likely.
PMID: 29628968 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 11, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Association between vitamin D and urinary tract infection in children.
Conclusion: This study showed that there was a relationship between serum 25(OH)D levels and UTI in children. It seems that 25(OH)D plays a role in the pathogenesis of UTI.
PMID: 29628969 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 11, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Acute kidney injury in pediatric patients with rhabdomyolysis.
Conclusion: The clinical characteristics of pediatric rhabdomyolysis differ from those observed in adult patients. Children with underlying diseases are more vulnerable to rhabdomyolysis-induced AKI. AKI more likely develops in the presence of a high degree of albuminuria.
PMID: 29628970 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 11, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Atypical hemolytic uremic syndrome and eculizumab therapy in children.
Authors: Kim SH, Kim HY, Kim SY
Abstract
Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is mainly plasmapheresis or plasma infusion; however, many children with aHUS will progress to chronic kidney disease despite p...
Source: Korean Journal of Pediatrics - March 25, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
