Two Cases of Mange Mite (Sarcoptes scabiei) Infestation in Long-Tailed Goral (Naemorhedus caudatus) in Republic of Korea
We report 2 cases of mange mite, Sarcoptes scabiei, infestation in long-tailed gorals. Mange mites were sampled in the skin legions of the 2 long-tailed gorals, which were rescued in 2 different regions, Uljin-gun, Gyeongsangbuk-do and Cheorwon-gun, Gangwon-do, Korea. Our results showed that the ectoparasite was the itch mite that burrowed into skin and caused scabies on the morphological inspection and placed within the phylogenetic relations of the species. The present study confirmed for the first time in Korea that mange mites are pathogenic scabies of long-tailed goral. Closer surveillance of this pathogenic ectoparas...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Da Som Park Jin Choi Hee-Jong Kim Jin-Yong Kim Min-Han Kim Jin-Young Lee Jeong Chan Moon Hee-Bok Park KyungMin Park Jun Hee Yun Yeonsu Oh Seongjun Choe Ki-Jeong Na Jongmin Yoon Source Type: research
Demodex Blepharitis: An Analysis of Nine Patients
Korean J Parasitol. 2022 Dec;60(6):429-432. doi: 10.3347/kjp.2022.60.6.429. Epub 2022 Dec 22.ABSTRACTInflammatory eyelid symptoms are common in primary care and there have been several reports on Demodex blepharitis. In the present study, we evaluate the 9 patients with Demodex blepharitis, who showed inflammation of the eyelids, dry eye, and cylindrical dandruff at the base of the eyelashes. The causative species from all patients was Demodex folliculorum of either the adult or nymph stage. Two patients had recurrent chalazion and 3 patients had keratitis. Weekly lid scrubs with 50% tee tree oil were performed for 6 weeks...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Young Il Lee Min Seo Kyong Jin Cho Source Type: research
Leishmania Vaccines: the Current Situation with Its Promising Aspect for the Future
Korean J Parasitol. 2022 Dec;60(6):379-391. doi: 10.3347/kjp.2022.60.6.379. Epub 2022 Dec 22.ABSTRACTLeishmaniasis is a serious parasitic disease caused by Leishmania spp. transmitted through sandfly bites. This disease is a major public health concern worldwide. It can occur in 3 different clinical forms: cutaneous, mucocutaneous, and visceral Leishmaniasis (CL, MCL, and VL, respectively), caused by different Leishmania spp. Currently, licensed vaccines are unavailable for the treatment of human Leishmaniasis. The treatment and prevention of this disease rely mainly on chemotherapeutics, which are highly toxic and have an...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Rasit Dinc Source Type: research
Genetic Diversity and Clustering of the Rhoptry Associated Protein-1 of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo
In this study, genetic analysis of PkRAP1 in a larger number of P. knowlesi samples from Malaysian Borneo was conducted. The PkRAP1 of these P. knowlesi isolates was PCR-amplified and sequenced. The newly obtained PkRAP1 gene sequences (n = 34) were combined with those from the previous study (n = 26) and analysed for polymorphism and natural selection. Sequence analysis revealed a higher genetic diversity of PkRAP1 compared to the previous study. Exon II of the gene had higher diversity (π = 0.0172) than exon I (π = 0.0128). The diversity of the total coding region (π = 0.0167) was much higher than those of RAP1 orthol...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Ummi Wahidah Azlan Yee Ling Lau Mun Yik Fong Source Type: research
In Vitro Evaluation of Two Novel Antimalarial Derivatives of SKM13: SKM13-MeO and SKM13-F
Korean J Parasitol. 2022 Dec;60(6):401-407. doi: 10.3347/kjp.2022.60.6.401. Epub 2022 Dec 22.ABSTRACTAntimalarial drugs play an important role in the control and treatment of malaria, a deadly disease caused by the protozoan parasite Plasmodium spp. The development of novel antimalarial agents effective against drug-resistant malarial parasites is urgently needed. The novel derivatives, SKM13-MeO and SKM13-F, were designed based on an SKM13 template by replacing the phenyl group with electron-donating (-OMe) or electron-withdrawing groups (-F), respectively, to reverse the electron density. A colorimetric assay was used to...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Thuy-Tien Thi Trinh Young-Ah Kim Hyelee Hong Linh Thi Thuy Le Hayoung Jang Soon-Ai Kim Hyun Park Hak Sung Kim Seon-Ju Yeo Source Type: research
Ectopic Schistosomiasis Involving Axillary Lymph Nodes
Korean J Parasitol. 2022 Dec;60(6):409-411. doi: 10.3347/kjp.2022.60.6.409. Epub 2022 Dec 22.ABSTRACTAxillary lymph node schistosomiasis is a form of ectopic schistosomiasis, in which the Schistosoma adult worms or eggs are infected in the axillary lymph nodes. A 53-year-old woman visited our hospital with a small mass in the right armpit, which had been present for over 1 month. Histological examination of biopsy samples from the right axillary lymph nodes revealed granulomas containing calcified Schistosoma eggs. This is the first authentic case of ectopic schistosomiasis identified in the axillary lymph nodes.PMID:36588...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Xia Chen Nian'an He Source Type: research
Imaging Manifestations and Misdiagnosis Analysis of Six Cases of Bone Hydatid Disease
Korean J Parasitol. 2022 Dec;60(6):413-417. doi: 10.3347/kjp.2022.60.6.413. Epub 2022 Dec 22.ABSTRACTWe retrospectively evaluated the clinical and imaging features of 6 patients with bone hydatid disease confirmed by surgery and pathological examination. Among the 6 patients, 2 were infected with Echinococcosis granulosus metacestode and 4 were infected with E. multilocularis metacestode. The 2 cases with cystic echinococcosis were diagnosed by computed tomographic (CT) examination, and other 4 cases were diagnosed by magnetic resonance (MR) imaging. On the initial evaluation, 1 case each was misdiagnosed as a giant cell t...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Yanqiu Sun Chunlong Yan Dengfeng Tian Chenhong Zhang Qiang Zhang Source Type: research
A Case of Ocular Sparganosis in China: Episode of Migration from Muscle Cone to Subconjunctiva
Korean J Parasitol. 2022 Dec;60(6):419-421. doi: 10.3347/kjp.2022.60.6.419. Epub 2022 Dec 22.ABSTRACTTo improve our understanding of the migration of sparganum in humans, we report a case of ocular sparganosis having the migratory episode from the muscle cone to the subconjunctiva. A 34-year-old woman was admitted to the Hospital of Anhui Medical University (Hefei, China), in December 2019. She presented with conjunctival hemorrhage and recurrent pain in the left eye. A foreign body was found in the muscle cone of the eye. Two months later, a ribbon-like white material was found under the conjunctiva on slit-lamp examinati...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Xinyuan Chen Yanyuan Fang Liming Tao Miao Liu Kun Liang Source Type: research
Two Cases of Mange Mite (Sarcoptes scabiei) Infestation in Long-Tailed Goral (Naemorhedus caudatus) in Republic of Korea
We report 2 cases of mange mite, Sarcoptes scabiei, infestation in long-tailed gorals. Mange mites were sampled in the skin legions of the 2 long-tailed gorals, which were rescued in 2 different regions, Uljin-gun, Gyeongsangbuk-do and Cheorwon-gun, Gangwon-do, Korea. Our results showed that the ectoparasite was the itch mite that burrowed into skin and caused scabies on the morphological inspection and placed within the phylogenetic relations of the species. The present study confirmed for the first time in Korea that mange mites are pathogenic scabies of long-tailed goral. Closer surveillance of this pathogenic ectoparas...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Da Som Park Jin Choi Hee-Jong Kim Jin-Yong Kim Min-Han Kim Jin-Young Lee Jeong Chan Moon Hee-Bok Park KyungMin Park Jun Hee Yun Yeonsu Oh Seongjun Choe Ki-Jeong Na Jongmin Yoon Source Type: research
Demodex Blepharitis: An Analysis of Nine Patients
Korean J Parasitol. 2022 Dec;60(6):429-432. doi: 10.3347/kjp.2022.60.6.429. Epub 2022 Dec 22.ABSTRACTInflammatory eyelid symptoms are common in primary care and there have been several reports on Demodex blepharitis. In the present study, we evaluate the 9 patients with Demodex blepharitis, who showed inflammation of the eyelids, dry eye, and cylindrical dandruff at the base of the eyelashes. The causative species from all patients was Demodex folliculorum of either the adult or nymph stage. Two patients had recurrent chalazion and 3 patients had keratitis. Weekly lid scrubs with 50% tee tree oil were performed for 6 weeks...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Young Il Lee Min Seo Kyong Jin Cho Source Type: research
Leishmania Vaccines: the Current Situation with Its Promising Aspect for the Future
Korean J Parasitol. 2022 Dec;60(6):379-391. doi: 10.3347/kjp.2022.60.6.379. Epub 2022 Dec 22.ABSTRACTLeishmaniasis is a serious parasitic disease caused by Leishmania spp. transmitted through sandfly bites. This disease is a major public health concern worldwide. It can occur in 3 different clinical forms: cutaneous, mucocutaneous, and visceral Leishmaniasis (CL, MCL, and VL, respectively), caused by different Leishmania spp. Currently, licensed vaccines are unavailable for the treatment of human Leishmaniasis. The treatment and prevention of this disease rely mainly on chemotherapeutics, which are highly toxic and have an...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Rasit Dinc Source Type: research
Genetic Diversity and Clustering of the Rhoptry Associated Protein-1 of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo
In this study, genetic analysis of PkRAP1 in a larger number of P. knowlesi samples from Malaysian Borneo was conducted. The PkRAP1 of these P. knowlesi isolates was PCR-amplified and sequenced. The newly obtained PkRAP1 gene sequences (n = 34) were combined with those from the previous study (n = 26) and analysed for polymorphism and natural selection. Sequence analysis revealed a higher genetic diversity of PkRAP1 compared to the previous study. Exon II of the gene had higher diversity (π = 0.0172) than exon I (π = 0.0128). The diversity of the total coding region (π = 0.0167) was much higher than those of RAP1 orthol...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Ummi Wahidah Azlan Yee Ling Lau Mun Yik Fong Source Type: research
In Vitro Evaluation of Two Novel Antimalarial Derivatives of SKM13: SKM13-MeO and SKM13-F
Korean J Parasitol. 2022 Dec;60(6):401-407. doi: 10.3347/kjp.2022.60.6.401. Epub 2022 Dec 22.ABSTRACTAntimalarial drugs play an important role in the control and treatment of malaria, a deadly disease caused by the protozoan parasite Plasmodium spp. The development of novel antimalarial agents effective against drug-resistant malarial parasites is urgently needed. The novel derivatives, SKM13-MeO and SKM13-F, were designed based on an SKM13 template by replacing the phenyl group with electron-donating (-OMe) or electron-withdrawing groups (-F), respectively, to reverse the electron density. A colorimetric assay was used to...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Thuy-Tien Thi Trinh Young-Ah Kim Hyelee Hong Linh Thi Thuy Le Hayoung Jang Soon-Ai Kim Hyun Park Hak Sung Kim Seon-Ju Yeo Source Type: research
Ectopic Schistosomiasis Involving Axillary Lymph Nodes
Korean J Parasitol. 2022 Dec;60(6):409-411. doi: 10.3347/kjp.2022.60.6.409. Epub 2022 Dec 22.ABSTRACTAxillary lymph node schistosomiasis is a form of ectopic schistosomiasis, in which the Schistosoma adult worms or eggs are infected in the axillary lymph nodes. A 53-year-old woman visited our hospital with a small mass in the right armpit, which had been present for over 1 month. Histological examination of biopsy samples from the right axillary lymph nodes revealed granulomas containing calcified Schistosoma eggs. This is the first authentic case of ectopic schistosomiasis identified in the axillary lymph nodes.PMID:36588...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Xia Chen Nian'an He Source Type: research
Imaging Manifestations and Misdiagnosis Analysis of Six Cases of Bone Hydatid Disease
Korean J Parasitol. 2022 Dec;60(6):413-417. doi: 10.3347/kjp.2022.60.6.413. Epub 2022 Dec 22.ABSTRACTWe retrospectively evaluated the clinical and imaging features of 6 patients with bone hydatid disease confirmed by surgery and pathological examination. Among the 6 patients, 2 were infected with Echinococcosis granulosus metacestode and 4 were infected with E. multilocularis metacestode. The 2 cases with cystic echinococcosis were diagnosed by computed tomographic (CT) examination, and other 4 cases were diagnosed by magnetic resonance (MR) imaging. On the initial evaluation, 1 case each was misdiagnosed as a giant cell t...
Source: Korean Journal of Parasitology - January 2, 2023 Category: Parasitology Authors: Yanqiu Sun Chunlong Yan Dengfeng Tian Chenhong Zhang Qiang Zhang Source Type: research
