[New Possibilities in Retinal Diagnostics Using OCT Angiography].
CONCLUSION: OCTA provides important three dimensional information on vascular alterations and is already an indispensable diagnostic method. As the procedure takes just a few seconds and can be performed non-invasively, OCTA is well suited as a monitoring method and may allow early diagnosis. In this sense, prospective studies are required to determine precise OCTA analytical strategies for specific diseases. It is very likely that OCTA will revolutionise the diagnosis of retinal and choroidal diseases; however, it is not yet clear estimated to what extent it will replace FA. PMID: 27187882 [PubMed - in process] (Sourc...
Source: Klinische Monatsblatter fur Augenheilkunde - May 19, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Therapeutic Options in Vitreomacular Traction With or Without a Macular Hole].
Authors: Maier M, Abraham S, Frank C, Lohmann CP, Feucht N Abstract Treatment is usually indicated for symptomatic vitreomacular traction (VMT) with or without a full thickness macular hole (FTMH) and without spontaneous resolution. Ultrastructural parameters are evaluated by SD-OCT, in order to classify the vitreoretinal interface and to estimate the success rate of treatment. The resolution rate after therapy with intravitreal Jetrea® (Ocriplasmin) is high (up to 70 %) in patients with symptomatic focal vitreomacular traction (≤ 1500 µm) with or without a macular hole (≤ 250...
Source: Klinische Monatsblatter fur Augenheilkunde - May 19, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Evaluation of Field of Vision in Private Accident Insurance].
Authors: Burggraf MH Abstract A simple new scheme to evaluate defects in field of vision in private accident insurance. PMID: 27187884 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 19, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Clinical Results After Implantation of a New Diffractive, Multifokal Intraocular Lens with a Reduced Near Add Power (+ 2.75 D)].
CONCLUSION: The ZKB00 IOL belongs to a group of novel MIOL with an increased intermediate visual performance. Our study shows good visual acuity at all distances, as well as a high rate of satisfaction and subjectively good image quality. PMID: 27187885 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 19, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Rare Conjunctival Metastasis in Cancer of Unknown Primary Syndrome].
Authors: Paul S, Vogelgesang S, Tost FH PMID: 27187886 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 19, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Seasonal and Perennial Allergic Rhinoconjunctivitis].
Authors: Schröder K, Finis D, Meller S, Buhren BA, Wagenmann M, Geerling G PMID: 27187887 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 19, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Investigation of Color Vision Using Pigment Color Plates and a Tablet PC].
Conclusions: Testing colour vision using book and tablet pc only gives roughly comparable results. However, separation with the book was better and the colour plates differed in validity. For this reason, only some of the colour plates could be used on a tablet PC. PMID: 27159326 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 10, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Retinal OCT: Vitreoretinal Interface].
Authors: Mayer WJ, Haritoglou C Abstract The gold standard for the assessment of the vitreoretinal interface (VRI) is high resolution OCT. It is therefore essential to select the appropriate scan modalities to detect all morphological changes in different diseases, not only at the VRI, but also in all layers of the retina and in the foveal and parafoveal areas. These can be raster scans, radial scans or "en face" scans. Morphological changes at the VRI and especially in the outer retinal layers are good prognostic factors in high resolution OCT for the success of surgery for vitreomacular interface disord...
Source: Klinische Monatsblatter fur Augenheilkunde - May 10, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Economic Short-Term Cost Model for Stereotactic Radiotherapy of Neovascular AMD].
Conclusions: The short-term economic analysis shows that anti-VEGF therapy combined with OT results in savings above the costs for OT itself over a 2 year time horizon. Overall, the approach gives potential cost reductions, if the appropriate indication is followed. PMID: 27130973 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 1, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Comparison of Functional and Morphological Outcome after Aflibercept or Ranibizumab in Chronic Recurrent Neovascular Age-Related Macular Degeneration].
Conclusions: Aflibercept and ranibizumab were similarly effective in improving visual acuity and morphological parameters of patients with recurrent nAMD after four months. There were no statistically significant differences in the therapeutic effects of the two drugs. PMID: 27130974 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 1, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Effect of Morphological and Functional Parameters on Ocular Pulse Amplitudes: An Analysis in Ocular Hypertension and Different Types of Glaucoma].
Conclusions: In this study, we showed that in the NTG group neither demographic nor morphological or functional factors affected OPA. However, in the OHT and POAG groups, OPA was influenced by IOP (measured with DCT), in the OHT and PEX group by MD and in the POAG and PEX groups by gender. PMID: 27130975 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 1, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Influence of Different Ablation Frequencies on the Clinical Results of Photorefractive Keratectomy Using the Same Excimer Laser Platform: A Contralateral Eye Study].
Conclusions: Photorefractive keratectomy with a repetition rate of 250 Hz and 500 Hz showed comparable efficacy, safety and predictability in the correction of myopia. There were no significant complications due to the high repetition rate, such as postsurgical corneal haze. PMID: 27130976 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 1, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Fiat Lux: Radium Radiation in 1903 - a Cure for the Blind?]
Authors: Gerstmeyer K, Scholtz SK, Kretz FT, Auffarth GU PMID: 27130977 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - May 1, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Value of Pressure Measurements: Methods and Sources of Errors].
Authors: Rüfer F Abstract Tonometry is still an essential component of diagnostic testing in glaucoma. Functional and morphological investigations can provide very detailed information about the extent of glaucomatous damage. They are useful in the early detection of glaucoma damage; when damage is manifest, they are useful in estimating the rate of progression in follow-up studies. In contrast, tonometric procedures are much less perfect and sensitive and provide no information at all about the extent of glaucoma damage. However, they often provide the first evidence that glaucoma may be present at all and th...
Source: Klinische Monatsblatter fur Augenheilkunde - May 1, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Trabeculotomy Combined with Cataract Surgery in Glaucoma: Outcome in a Rural Setting].
The objective of this study was to examine the outcome of trabeculotomy combined with cataract surgery in patients with glaucoma. Patients and Methods: 142 patients with glaucoma and cataract were included in a retrospective clinical study. All patients were operated on from November 2005 to December 2008 by a single surgeon and with a minimum follow-up of 2 months. Intraocular pressure (IOP), number of antiglaucomatous medications and surgical success rate were assessed at 2 months and at the longest follow-up (at least 1 year). Results: IOP was significantly reduced from 24.1 ± 8.3 mmHg preope...
Source: Klinische Monatsblatter fur Augenheilkunde - April 30, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Switching Therapy from Ranibizumab and/or Bevacizumab to Aflibercept in Neovascular Age-Related Macular Degeneration (AMD): One-Year Results].
Authors: Pfau M, Fassnacht-Riederle HM, Freiberg FJ, Wons JB, Wirth M, Becker MD, Michels S Abstract Background: The presented study is a retrospective evaluation of switching therapy from ranibizumab and/or bevacizumab to aflibercept in neovascular age-related macular degeneration in patients who had previously given an insufficient response to therapy with ranibizumab and/or bevacizumab. Patients and Methods: 96 eyes with neovascular age-related macular degeneration (AMD) were included, which had been pretreated with ranibizumab and/or bevacizumab (T&E), but had responded insufficiently. An injection interval...
Source: Klinische Monatsblatter fur Augenheilkunde - April 30, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Do Naranjo Criteria Still Apply to Ipilimumab-induced Uveitis?
Authors: Guex-Crosier Y PMID: 27116481 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Is it still Necessary to Discontinue Using Daily Wear Soft Contact Lenses for a Period before LASIK?].
DISCUSSION: The differences in the measurements during this study suggest that a modern soft contact lenses should still be discontinued before LASIK. The optimal duration of the discontinuation remains to be determined. PMID: 27116482 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

AcuFocus Corneal Inlay to Correct Presbyopia Using Femto-LASIK. One Year Results of a Prospective Cohort Study.
Authors: Jalali S, Aus der Au W, Shaarawy T Abstract Purpose: To evaluate the safety and efficacy of the AcuFocus small aperture corneal inlay (KAMRA) for the correction of presbyopia using femto-LASIK. Patients and Methods: This is a prospective, non-randomised cohort study including 50 presbyopic patients with hyperopia, emmetropia or mild myopia. The intracorneal inlay was implanted in the non-dominant eye using a VisuMax femtosecond laser (Zeiss 500 kHz) to create a superior-hinged flap. The inlay was centred over the visual axis. Minimum postoperative follow-up was performed for a period of 12 months. R...
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Implantation of an Artificial Iris in 11 Patients].
Conclusions. In patients with major iris defects, the artificial iris allows functionally and aesthetically satisfactory reconstruction of the anterior segment. PMID: 27116484 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Repeated Intrastromal Injections of Voriconazole in Combination with Corneal Debridement for Recalcitrant Fungal Keratitis - a Case Series.
Conclusions: Repeated intrastromal injection of voriconazole in combination with corneal debridement appears to be an effective and safe way to treat recalcitrant fungal keratitis, even in Fusarium keratitis. PMID: 27116485 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Urrets-Zavalia Syndrome after Iris-Claw-Lens Implantation, Inadequate Iridectomy and Acute Glaucoma.
Authors: Arendt P, Gerding H PMID: 27116486 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Therapeutic Use of Botulinum Toxin to Correct Misalignment of the Eyes].
CONCLUSIONS: Botulinum toxin has a lasting effect, especially in children with esotropia. It is minimally invasive and can prevent surgery. If there is subsequent surgery, the dosage may be reduced. Ptosis rates were comparable to those in the literature. PMID: 27116487 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Eyeglasses for Children - a Survey of Daily Practice.
Authors: Hagander CE, Traber G, Landau K, Jaggi GP Abstract Background: Glasses for children are recommended and prescribed by different groups of professionals. We set out to compare the prescription practices of ophthalmologists, orthoptists and optometrists/opticians in Switzerland. Methods: Online questionnaire on the prescription and recommendation of glasses in fictitious cases of children of different ages, refractive values and symptoms. The questionnaire was sent out to members of the Swiss Ophthalmological Society, Swiss Orthoptics and Schweizerischer Berufsverband für Augenoptik und Optometrie. Resu...
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Unexpected Effect of Calcium Channel Blockers on the Optic Nerve Compartment Syndrome.
Conclusions: To some extent, the optic nerve compartment syndrome is related to the combination of primary open angle glaucoma and Flammer syndrome. On the basis of our results, we hypothesise that treatment of Flammer syndrome may also improve the optic nerve compartment syndrome. PMID: 27116489 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Vision Screening in Zurich].
CONCLUSIONS: Vision screening by the school medical services enrols most of the children from a single age group. The Snellen E charts used for the monocular distance acuity, together with the TNO stereo test, appear to constitute an effective testing combination. Ophthalmological follow-up examinations of the affected children revealed that one third were afflicted by amblyogenic factors. PMID: 27116490 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Transsynaptic Retrograde Degeneration: Clinical Evidence with Homonymous RGCL Loss on OCT.
Conclusions: The homonymous defect of RGCL in patients with retrogeniculate lesions demonstrates the presence of transsynaptic retrograde degeneration. RGCL is a better predictor of visual field defects than RNFL measurement. PMID: 27116491 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Sequential Bilateral Non-Arteritic Anterior Ischaemic Optic Neuropathy in Superficial Intracranial Siderosis.
Authors: Enz TJ, Clavadetscher SC, Gugleta K, Jaggi GP PMID: 27116492 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Acute Lid Swelling: a Series of Unusual Cases, Treatment and Follow-up.
Conclusions: The key to success often lies in the assessment of the patient's history and correctly timed surgery. Dramatic first manifestations were often easier to treat than initially low grade lid swelling. Unclear results, such as a low grade eosinophilia, should not be ignored. PMID: 27116493 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Temporary Medial Upper Eyelid Lagophthalmos after External Dacryocystorhinostomy.
Conclusions. Temporary lagophthalmos can occur as a complication of external dacryocystorhinostomy, most likely due to damage of the (only recently described) superficial buccal and/or zygomatic branches of the facial nerve that run upward to cross over the medial ligament and innervate the medial part of the orbicularis oculi muscle. PMID: 27116494 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Subkutanes Granuloma anulare am Orbitarand kann eine Dermoidzyste imitieren.
Authors: Rothenbuehler SP, Obermann EC, Itin PH, Goldblum D PMID: 27116495 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Endonasal Dacryocystorhinostomy (DCR) with Transcanalicular Endoillumination (TCE) of the Saccus Lacrimalis].
Authors: Hefner J, Klask J, Gerding H Abstract Endonasal dacryocystorhinostomy (DCR) has been established as a standard procedure of lacrimal surgery, since it causes much less tissue damage than ab externo procedures. Diffiulties in visualization of the target area has been a limitation to the transnasal approach. An improvement of the classical endonasal DCR was achieved by the introduction of a transcanalicular endoillumination (TCE) of the lacrimal sac using a 23-Gauge vitreoretinal light probe, which can easily be intubated into the cannaliculi and advanced into the the lacrimal sac. Illumination of the lacrim...
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

A Novel Technique of Plastic Evisceration for Larger Implants.
Authors: Gerding H, Arendt P PMID: 27116497 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Improvement in Visual Function in Patients with Inherited Diseases of the Retina Following Acupuncture Treatment.
Conclusions: The acupuncture protocol improved visual function in our patients with inherited diseases of the retina and was well tolerated. Nevertheless, the long-term effect of this complementary therapy remains to be evaluated. PMID: 27116498 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Malposition of Teeth and Jaws in Patients with Congenital Superior Oblique Palsy.
Conclusions: In this small study, three orthodontic parameters correlated with orthoptic findings in patients with congenital superior oblique palsy. Further studies are needed to establish whether congenital superior oblique palsy is more frequent in patients exhibiting abnormal values of these orthodontic parameters. PMID: 27116499 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Unilateral Loss of Vision after Spinal Surgery in a Patient with Flammer Syndrome.
Authors: Bojinova RI, Konieczka K, Todorova MG PMID: 27116500 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

[Calcified Phthisis Bulbi: Development and Pathology in a Case History].
Authors: Zahiti-Rashiti K, Meyer P, Goldblum D PMID: 27116501 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

SLO Fundus Imaging Is the Most Sensitive Modality of Multimodal Imaging for Macular Microembolisms with Subtle Signs.
Conclusions. Macular ischemia due to microemboli can show obvious fundus signs as hemorrhages, cotton wool spots and non perfusion or can present in a subclinical fashion. The SLO picture has a higher image contrast and higher resolution compared to conventional fundus photography and so can precisely delineate ischemic changes of the inner retina causing the unexplained visual loss. PMID: 27116502 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Peripheral Bilateral Telangiectasiae in Multiple Sclerosis Patients Treated with Interferon B1a.
Authors: de Massougnes S, Borruat FX, Ambresin A PMID: 27116503 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Anatomical and Functional Results of Lamellar Macular Holes Surgery.
Conclusion: We demonstrated improvement in postoperative vision and the anatomical reconstruction of the anatomical contour of the fovea in most eyes with symptomatic lamellar holes. These findings indicate that vitrectomy, membranectomy and ILM peeling with gas tamponade is a beneficial treatment of symptomatic lamellar macular holes. PMID: 27116504 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion.
Authors: Konstantinidis L, Bissig A, Pournaras JA, Wolfensberger TJ Abstract Background: Without treatment, the natural history of central retinal vein occlusion (CRVO) can result in severe loss of vision. Material and Methods: This was a retrospective study of 10 eyes with CRVO treated with pars plana vitrectomy (PPV), combined with radial optic neurotomy. The patients completed a minimum of 5 years follow-up. Results: Median age at the time of surgery was 67 ± 14 years. Median follow-up was 79 ± 9 months. Ischaemic changes were present in 4 patients pre-operatively. Basel...
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Increased Prevalence of Flammer Syndrome in Patients with Retinitis Pigmentosa.
Conclusion: Retinitis pigmentosa patients suffer significantly more often from symptoms and signs of the Flammer syndrome than control subjects. This includes low body mass index, low blood pressure, feeling cold, migraine, increased smell perception and perfectionism. The reason for this association between retinitis pigmentosa and Flammer syndrome and the potential implications need to be determined. PMID: 27116506 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Transient Subfoveal Fluid and Visual Loss after Ocriplasmin.
Conclusions: In the light of the documented adverse effects of the registration trial, the relatively high rate of subfoveal fluid after injecting ocriplasmin was surprising. Possible causes include enzymatic lysis of the matrix between the outer segments of the photoreceptors and the microvilli of the RPE-cells, or barrier disturbances in the RPE through lysis of the zonulae occludentes. PMID: 27116507 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

A Novel Recessive RPGRIP1 Mutation Causing Leber Congenital Amaurosis.
Conclusions: Identifying new mutations in Leber congenital amaurosis-related genes and their clinical manifestations can improve our understanding of the disease and could help to stratify the population for potential therapies. PMID: 27116508 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Acid Violet 17: a New Dye for Chromovitrectomy?
Conclusions: Preclinical tests indicate that AV17 has toxic and undesired effects at concentrations much lower than claimed by suppliers. Against the background of these data and the first observations of adverse clinical effects, it seems advisable to be cautious when using AV17. PMID: 27116509 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Effect of Risk Alleles in CFH, C3, and VEGFA on the Response to Intravitreal Bevacizumab in Tunisian Patients with Neovascular Age-related Macular Degeneration.
Conclusions. The VEGF haplotype TGA could be used as a marker for poor visual prognosis in Tunisian patients with neovascular AMD treated with bevacizumab. PMID: 27116510 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Long-term Results of Intravitreal Anti-VEGF Injections in Wet AMD: A Meta-Analysis.
Conclusions: The results of this meta-analysis clearly indicate that intravitreal anti-VEGF injection therapy is capable of maintaining visual acuity on a long-term basis of at least 4-5 years. PMID: 27116511 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Swiss Family with Dominant Stargardt Disease Caused by a Recurrent Mutation in the ELOVL4 Gene.
Authors: Tran HV, Moret E, Vaclavik V, Marcelli F, Abitbol MM, Munier FL, Schorderet DF PMID: 27116512 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Incidence and Surgical Management of Simultaneous Bilateral Retinal Detachment.
Conclusion: The incidence of bilateral simultaneous RD appears to be very low and surgical success rates are excellent. Bilateral pre-operative dilated fundoscopy is mandatory, as the majority of patients have unilateral symptoms. PMID: 27116513 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Angioid Streaks in Types I and II Congenital Dyserythropoietic Anaemia (CDA).
Conclusions. This is the first report of AS in CDA II and the first follow-up in CDA I. No evidence of progression was seen within this period of time. Longer follow-up is needed to detect whether AS progresses. All patients with AS should be seen by an ophthalmologist on a regular basis. The risk of CNV is given. Therapy is possible and the outcome is best if the CNV is recognised and treated early. PMID: 27116514 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 28, 2016 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research