Acknowledgment of reviewers
The quality of a journal depends on several components: the Authors and their work, the Editors and their efforts to attract the best authors and disseminate their work, and the peer review, which maintains scientific integrity, pushes authors to get the most out of their data, and ensures the work is understandable and important for the overall readership. The Editors are very grateful to the following Reviewers who devoted time to produce high-quality reviews of the manuscripts submitted to Kidney International in 2023. (Source: Kidney International)
Source: Kidney International - April 18, 2024 Category: Urology & Nephrology Tags: Acknowledgment Source Type: research
Editorial Board
(Source: Kidney International)
Source: Kidney International - April 18, 2024 Category: Urology & Nephrology Source Type: research
Subscription Information
(Source: Kidney International)
Source: Kidney International - April 18, 2024 Category: Urology & Nephrology Source Type: research
Table of Contents
(Source: Kidney International)
Source: Kidney International - April 18, 2024 Category: Urology & Nephrology Source Type: research
NELL-1 –associated membranous nephropathy linked to skin fairness cream use: insights from an Indian case series
Neural epidermal growth factor-like protein 1 (NELL-1) is an autoantigen associated with both primary and secondary membranous nephropathy (MN) and is described with malignancy, autoimmune diseases, lipoic acid, and traditional indigenous medicines.1 –6 (Source: Kidney International)
Source: Kidney International - April 11, 2024 Category: Urology & Nephrology Authors: Ranjit Narayanan, Sajeesh Sivadas, Anila Abraham Kurien Tags: Research Letter Source Type: research
NELL-1 associated membranous nephropathy linked to skin fairness cream use- insights from an Indian case series
Neural epidermal growth factor-like protein 1 (NELL-1) is an autoantigen associated with both primary and secondary membranous nephropathy (MN) and is described with malignancy, autoimmune diseases, lipoic acid and traditional indigenous medicines (TIM).1-6 (Source: Kidney International)
Source: Kidney International - April 11, 2024 Category: Urology & Nephrology Authors: Ranjit Narayanan, Sajeesh Sivadas, Anila Abraham Kurien Tags: research letter Source Type: research
Unexpected metabolic effects of sodium-glucose cotransporter 2 inhibitors
The sodium-glucose cotransporter 2 (SGLT2) is exclusively expressed in the brush border of the proximal tubule of the kidney, where it effects glucose reabsorption. However, a recent study of young persons with type 2 diabetes (T2D) and early kidney injury showed that treatment with SGLT2 inhibitors (SGLT2i) was associated with significant transcriptional changes across virtually all tubular segments in the kidney.1 SGLT2i are not only effective in treating diabetic kidney disease but also in protecting against both heart and kidney failure in various types of chronic kidney disease (CKD). (Source: Kidney International)
Source: Kidney International - April 10, 2024 Category: Urology & Nephrology Authors: Tilman B. Drueke, Ziad A. Massy Tags: Nephrology Digest Source Type: research
Deciphering missense coding variants with AlphaMissense
Genetic diagnosis promises to guide treatment and manage expectations for patients and physicians. Yet even when a variant in a disease gene is identified, the assignment of pathogenic impact is not always possible.1 Of the 215 million possible substitutions in approximately 19,900 genes, 71 million are missense mutations that result in an amino acid substitution rather than a stop codon or a frameshift.2 Only 4 million missense variants have been observed, of which approximately 2% have been clinically classified as pathogenic or benign by testing companies and collected in the public ClinVar repository. (Source: Kidney International)
Source: Kidney International - April 10, 2024 Category: Urology & Nephrology Authors: Zhicheng Pan, Chandra L. Theesfeld Tags: Nephrology Digest Source Type: research
The key role of altered tubule cell lipid metabolism in kidney disease development
Kidney epithelial cells have very high energy requirements, which are largely met by fatty acid oxidation. Complex changes in lipid metabolism are observed in patients with kidney disease. Defects in fatty acid oxidation and increased lipid uptake, especially in the context of hyperlipidemia and proteinuria, contribute to this excess lipid build-up and exacerbate kidney disease development. Recent studies have also highlighted the role of increased de novo lipogenesis in kidney fibrosis. The defect in fatty acid oxidation will cause energy starvation. (Source: Kidney International)
Source: Kidney International - April 10, 2024 Category: Urology & Nephrology Authors: Lauren E. Lee, Tomohito Doke, Dhanunjay Mukhi, Katalin Susztak Tags: review Source Type: research
Bridging the knowledge –practice gap in kidney care: insights from a medical student in Thailand
As a medical student at King Chulalongkorn Memorial Hospital, Bangkok, I found the article “Mind the gap in kidney care: translating what we know into what we do” published in Kidney International1 deeply resonant with my observations in our dialysis unit. (Source: Kidney International)
Source: Kidney International - April 5, 2024 Category: Urology & Nephrology Authors: Abhishet Varama Tags: Letter to the Editor Source Type: research
The authors reply
Responding to the letter from Tantisattamo, we are grateful for the interest in our paper on improving kidney care through effective implementation of available scientific knowledge in real-world clinical practices. The author highlighted a framework to help clinicians systematically consider achievable goals in terms of implementation, service, and clinical outcomes.1 We agree that implementation science is advancing and certainly may help to promote the use of effective drugs in real-world settings, such as the use of sodium-glucose cotransporter 2 inhibitors. (Source: Kidney International)
Source: Kidney International - April 5, 2024 Category: Urology & Nephrology Authors: Winston W.S. Fung, Valerie A. Luyckx, Katherine R. Tuttle, writing team and the World Kidney Day Joint Steering Committee Tags: Letter to the Editor Source Type: research
Bridging the knowledge —practice gap in kidney care: insights from a medical student in Thailand
As a medical student at King Chulalongkorn Memorial Hospital, Bangkok, I found the article “Mind the gap in kidney care: translating what we know into what we do” published in Kidney International1 deeply resonant with my observations in our dialysis unit. (Source: Kidney International)
Source: Kidney International - April 5, 2024 Category: Urology & Nephrology Authors: Abhishet Varama Tags: Letter to the Editor Source Type: research
The authors reply
We thank the author for his interest and comments on this important topic on translating what we know into what we do in kidney care1 and for highlighting Thailand ’s success in integrating dialysis and kidney care within its universal health coverage.2 We agreed that this may be a commendable model for extending critical health care services, especially for middle-income countries. Indeed, this was shown in the ESCORT studies in Thailand, where an integrate d comprehensive multidisciplinary kidney care program was shown to delay kidney disease progression, even in resource-limited settings. (Source: Kidney International)
Source: Kidney International - April 5, 2024 Category: Urology & Nephrology Authors: Winston W.S. Fung, Valerie A. Luyckx, Katherine R. Tuttle, writing team and the World Kidney Day Joint Steering Committee Tags: Letter to the Editor Source Type: research
Response to Implementation Science: A Tool to Narrow Know-Do Gap and Widen Equity in Kidney Diseases and Transplantation
Responding to the letter from Tantisattamo et al, we are very grateful for the interest in our paper on improving kidney care through effective implementation of available scientific knowledge into real-world clinical practices. The author highlighted a framework to help clinicians to systematically think of the achievable goal into implementation, service, and clinical outcomes [1]. We agree that implementation science is advancing and certainly may help to promote the usage of effective drugs in real-world settings such as the use of sodium glucose cotransporter 2 inhibitors [2]. (Source: Kidney International)
Source: Kidney International - April 5, 2024 Category: Urology & Nephrology Authors: Winston W.S. Fung, Valerie A. Luyckx, Katherine R. Tuttle, writing team and the World Kidney Day Joint Steering Committee Tags: letters to the editor Source Type: research
Bridging the Knowledge – Practice Gap in Kidney Care: Insights from a Medical Student in Thailand
As a medical student at King Chulalongkorn Memorial Hospital, Bangkok, I found the article 'Mind the gap in kidney care: translating what we know into what we do' published in Kidney International1, deeply resonant with my observations in our Dialysis unit. (Source: Kidney International)
Source: Kidney International - April 5, 2024 Category: Urology & Nephrology Authors: Abhishet Varama Tags: letters to the editor Source Type: research
