Alarmingly High Incidence of Eosinophilia in Barabanki and Neighboring Districts of Eastern Uttar Pradesh: A Prospective Hospital-Based Study
Eosinophilia is very common among rural poulation in Barabanki and neighbouring districts with no access to hygienic mode of stool disposition. Significant proportions of these children are suffering from anemia, undernutrition, anorexia, pain abdomen, cough and hence long term morbidity. This adds to the DALY of a developing country like India. All these chronic problems are preventable and treatable with simple corrective steps of which the most important ones are access to safe drinking water and toilet. The present study was conducted to study clinical and laboratory profile of patients with eosinophilia and to identif...
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Thakur, N., Rai, N. Tags: Research Letter Source Type: research

Histoplasma capsulatum Infection with Extensive Lytic Bone Lesions Mimicking LCH
We report a case of histoplasmosis, caused by H. capsulatum var. capsulatum with extensive lytic bone lesions in a 13 year old immunocompetent boy who presented with prolonged fever, weight loss and multiple boggy swellings. He responded to amphotericin and is currently on Itraconazole. This case is unique for extensive osteolytic lesions with H. capsulatum var. capsulatum infection in an immunocompetent child. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Mathews, D. M., John, R., Verghese, V., Parmar, H., Chaudhary, N., Mishra, S., Mathew, L. Tags: Case Reports Source Type: research

Acute Abdominal Pain as a Presenting Symptom of Beriberi in a Pediatric Patient
Vitamin B1 (thiamine) plays a fundamental role in the proper functioning of the nervous and cardiovascular systems and in glucose metabolism. Because of the inability of the human body to store large amounts of vitamin, continuous restoration through diet is necessary. In the pediatric population, thiamine deficiency has a broad spectrum of clinical presentations, making diagnosis difficult. In this article, we report the case of a 7-month-old child with thiamine deficiency presented with neurological symptoms and simulation of acute abdomen. The patient received thiamine replacement, which resulted in rapid reversal of me...
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Nogueira, R. J. N., Godoy, J. E., Souza, T. H. Tags: Case Reports Source Type: research

N-acetylcysteine in Cleistanthus collinus Poisoning: A Report of Two Cases in Children
We report two previously healthy male siblings of pediatric age group who ingested the liquid extracted from crushed leaves of this plant given to them by their mother as a means of deliberate harm. Both patients developed distal renal tubular acidosis, with hypokalemia. The younger sibling also developed myocardial toxicity. Other significant findings noted include hypocalcemia, hypomagnesemia and elevated liver enzymes. Both patients received supportive care along with N-acetylcysteine infusion, and showed complete recovery within 10 days. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Sharma, S., Rameshkumar, R., Mahadevan, S. Tags: Case Reports Source Type: research

Hematological Differences among Malaria Patients in Rural and Urban Ghana
Conclusion: These results indicate that children living in urban setting may experience a greater anemic effect to malaria as compared with those living in a rural setting. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Iqbal, S. A., Botchway, F., Badu, K., Wilson, N. O., Dei-Adomakoh, Y., Dickinson-Copeland, C. M., Chinbuah, H., Adjei, A. A., Wilson, M., Stiles, J. K., Driss, A. Tags: Original Papers Source Type: research

Impact of Telemedicine in the Screening for Congenital Heart Disease in a Center from Northeast Brazil
Conclusion: The implementation of a screening process model for congenital heart diseases can change the context of patients with congenital heart diseases in poor regions. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: de Araujo, J. S. S., Regis, C. T., Gomes, R. G. S., Mourato, F. A., Mattos, S. d. S. Tags: Original Papers Source Type: research

Efficacy and Safety of Saccharomyces boulardii in Acute Rotavirus Diarrhea: Double Blind Randomized Controlled Trial from a Developing Country
Conclusions: The present trial showed that SB is effective and safe in acute rotavirus diarrhea. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Das, S., Gupta, P. K., Das, R. R. Tags: Original Papers Source Type: research

Association between the Specific UGT1A1 Promoter Sequence Variant (c-3279T>G) and Unconjugated Neonatal Hyperbilirubinemia
We investigated the association between c-3279T>G and unconjugated neonatal hyperbilirubinemia. In all, 141 neonates were recruited; 63 had hyperbilirubinemia necessitating treatment, and 78 with bilirubin < 7 mg/dl served as the control group. The frequency of occurrence of c-3279T > G allele was significantly higher in the hyperbilirubinemic (49.2%) than in the control group (25.6%). The homozygous (p = 0.001, OR = 17.7 and CI = 3.9–79.3) rather than the heterozygous state (p = 0.3, OR = 0.7 and CI = 0.3–1.6) was associated with hyperbilirubinemia. Among the hyperbilirubinemic group, comparison betwe...
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Tomerak, R. H., Helal, N. F., Shaker, O. G., Yousef, M. A. Tags: Original Papers Source Type: research

A Community-based Study on Growth and Development of Under-Five Children in an Urbanized Village of South Delhi
Conclusions: The study concludes that developmental delay is present in a sizable proportion of children <5 years of age and may be a significant factor in the overall achievement of life’s potential in them. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Dabar, D., Das, R., Nagesh, S., Yadav, V., Mangal, A. Tags: Original Papers Source Type: research

Is the WHO Guide on Essential Practice of Postpartum Newborn Care Used in a District Health Care Facility?
Conclusion: Nurse-midwives’ expertise in the WHO guide on postpartum newborn care cannot be taken for granted. The complexity of this guide demands expertise and makes its use time-consuming and thus its practicability disputable in a setting with limited resources. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Klinkott, R., Mushi, V., Komba, G., Krüger, C., Schultz, A., Stich, A., Stüfe, A., Weber, M., Ehrhardt, S. Tags: Original Papers Source Type: research

Assessment of Adequacy of Supplementation of Vitamin D in Very Low Birth Weight Preterm Neonates: A Randomized Controlled Trial
Conclusion: Vitamin D supplementation in a dose of 1000 IU/day is more effective in maintaining serum calcium, phosphate, ALP, 25-OHD and parathormone levels with lower incidence of skeletal hypomineralization and better growth. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Authors: Mathur, N. B., Saini, A., Mishra, T. K. Tags: Original Papers Source Type: research

In this issue 62/6
(Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 6, 2016 Category: Tropical Medicine Tags: In this issue Source Type: research

Fatal Neonatal Peritoneal Candidiasis Mimicking Mucormycosis--A Case Report and Review of Literature
We report a case of fatal neonatal peritoneal candidiasis which was misdiagnosed as mucormycosis. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - September 27, 2016 Category: Tropical Medicine Authors: Kashyap, B., Kusumakar, K., Kumar Sarin, Y. Tags: Case Report Source Type: research

Irradiance Decay in Fluorescent and Light-emitting Diode-based Phototherapy Devices: A Pilot Study
We set out to determine the rate of decline of irradiance for fluorescent tube (FT) and light-emitting diode (LED) phototherapy devices in resource-limited settings where routine irradiance monitoring is uncommon. Irradiance levels (μW/cm2/nm) were measured weekly using BiliBlanket® II Meter on three FT-based and two LED-based phototherapy devices over a 19 week period. The two LED devices showed stable irradiance levels and did not require any lamp changes. The three FT-based devices showed rapid decline in irradiance, and all required three complete lamp exchanges approximately every 5–6 weeks. FT-based devi...
Source: Journal of Tropical Pediatrics - September 27, 2016 Category: Tropical Medicine Authors: Olusanya, B. O., Osibanjo, F. B., Emokpae, A. A., Slusher, T. M. Tags: Brief Report Source Type: research

Distribution of Eschar in Pediatric Scrub Typhus
Conclusion: Children should be carefully examined for the presence of eschar especially in the skin folds of the genitalia, axillae and groin to make an early diagnosis of scrub typhus. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - September 27, 2016 Category: Tropical Medicine Authors: Rose, W., Rajan, R. J., Punnen, A., Ghosh, U. Tags: Original Papers Source Type: research