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A novel animal model of primary blast lung injury and its pathological changes in mice
CONCLUSION The self-made mini shock tube simulation device can be used to establish the animal model of PBLI successfully. Pathological changes of PBLI mice were characterized by mechanical damage and inflammatory response in lung tissue. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: INDEPENDENT SUBMISSIONS Source Type: research

Prehospital activation of a coordinated multidisciplinary hospital response in preparation for patients with severe hemorrhage: A statewide data linkage study of the New South Wales “Code Crimson” pathway
This study reports the initial experience of an Australian “Code Crimson” (CC) pathway facilitating early multidisciplinary care for these patients. METHODS This data-linkage study combined prehospital databases with a trauma registry of patients with an Injury Severity Score greater than 12 between 2017 and 2019. Four groups were created; prehospital CC activation with and without in-hospital links and patients with inpatient treatment consistent with CC, without one being activated. Diagnostic accuracy was estimated using capture-recapture methodology to replace the missing cell (no prehospital CC and Injury S...
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: INDEPENDENT SUBMISSIONS Source Type: research

Emergency department return visits and hospital admissions in trauma team assessed patients initially discharged from the emergency department: A population-based cohort study
CONCLUSION Patients discharged directly have high rates of ED return visits but low rates of hospital admission or delayed surgical intervention. Trauma services should expand quality assurance initiatives to capture return visits, understand any gaps in clinical service provision, and aim to minimize unnecessary ED return visits. LEVEL OF EVIDENCE Prognostic/Epidemiological; Level IV. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: INDEPENDENT SUBMISSIONS Source Type: research

Differences in time-critical interventions and radiological examinations between adult and older trauma patients: A national register-based study
CONCLUSION Older trauma patients were less likely to receive advanced prehospital care compared with younger adults. Older patients with very severe injuries received fewer time-critical interventions and radiological examinations. Improved dispatch of doctor/paramedic teams to older adults and assessment of the impact the observed differences have on outcome are future research priorities. LEVEL OF EVIDENCE Therapeutic/Care Management; Level III. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: INDEPENDENT SUBMISSIONS Source Type: research

Intravenous lidocaine for the management of traumatic rib fractures: A double-blind randomized controlled trial (INITIATE program of research)
CONCLUSION These results demonstrate that lidocaine has a beneficial analgesic effect in patients with TRFs. Future work is needed to evaluate lidocaine's ability to reduce patient important consequences of inadequate analgesia. LEVEL OF EVIDENCE Therapeutic/Care Management; Level II. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: INDEPENDENT SUBMISSIONS Source Type: research

The anchor point algorithm: A morphometric analysis of anatomic landmarks to guide placement of temporary aortic Rescue stent grafts for noncompressible torso hemorrhage
CONCLUSION Simple anatomic metrics offer rapid triage in this study population to one of three presized stent grafts and predict the location of key vascular branches. Confirmatory human trials will be essential to demonstrate safety and effectiveness of this approach. LEVEL OF EVIDENCE Prognostic/Epidemiological; Level IV. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: INDEPENDENT SUBMISSIONS Source Type: research

Youth violence prevention can be enhanced by geospatial analysis of trauma registry data
BACKGROUND Geographic information systems (GIS) have been used to understand relationships between trauma mechanisms, locations, and social determinants for injury prevention. We hypothesized that GIS analysis of trauma center registry data for assault patients aged 14 years to 29 years with census tract data would identify geospatial and structural determinants of youth violence. METHODS Admissions to a Level I trauma center from 2010 to 2019 were retrospectively reviewed to identify assaults in those 14 years to 29 years. Prisoners were excluded. Home and injury scene addresses were geocoded. Cluster analysis ...
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2021 WTA PODIUM PAPER Source Type: research

Derivation and validation of an improved pediatric shock index for predicting need for early intervention and outcomes in pediatric trauma
CONCLUSION We derived the PSI and rPSI for use in pediatric trauma using empiric, age-based SI cutoffs. The PSI and rPSI achieved higher positive predictive values and similar negative predictive values to SIPA in predicting the need for early blood transfusion and mortality. LEVEL OF EVIDENCE Prognostic/Epidemiological; level III. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2021 PTS PODIUM PAPER Source Type: research

Establishing national stakeholder priorities for quality improvement in pediatric trauma care: Consensus results using a modified Delphi process
CONCLUSION System-level quality improvement priorities for pediatric trauma care should focus resources on developing and implementing minimum pediatric standards for injury care, frontline provider training, stabilization protocols, imaging guidelines, and local pediatric champions. LEVEL OF EVIDENCE Therapeutic/Care Management; Level IV. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2021 PTS PODIUM PAPER Source Type: research

Scalable deep learning algorithm to compute percent pulmonary contusion among patients with rib fractures
CONCLUSION We developed a scalable deep learning algorithm to automate percent pulmonary contusion calculating using chest computed tomography scans of adults admitted with rib fractures. Open code sharing and collaborative research are needed to validate our algorithm and exploratory analysis at a large scale. Transfer learning can help harness the full potential of big data and high-performing algorithms to bring precision medicine to the bedside. LEVEL OF EVIDENCE Prognostic and epidemiological, Level III. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2022 EAST QUICK SHOT Source Type: research

Fibrinogen supplementation for the trauma patient: Should you choose fibrinogen concentrate over cryoprecipitate?
CONCLUSION Fibrinogen supplementation in the form of FC for the traumatic hemorrhagic patient is associated with improved outcomes and reduced transfusion requirements as compared with Cryo. Further studies are required to evaluate the optimal method of fibrinogen supplementation in the resuscitation of trauma patients. LEVEL OF EVIDENCE Therapeutic/Care Management; Level III. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2022 EAST PODIUM PAPER Source Type: research

Which hospital-acquired conditions matter the most in trauma? An evidence-based approach for prioritizing trauma program improvement
CONCLUSION We describe a method for comparing the contributions of HACs to outcomes of hospitalized trauma patients. Our findings suggest that trauma program improvement efforts should prioritize pneumonia prevention. LEVEL OF EVIDENCE Therapeutic/Care Management; Level IV. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2020 AAST POSTER Source Type: research

Burnout reduction in acute care surgeons: Impact of faculty schedule change at a level 1 trauma and tertiary care center
CONCLUSION This study demonstrates that implementing a weekly, 12-hour call schedule can improve factors leading to burnout. Improvements were noted in surgeon and family groups alike, signifying both subjective improvements and observed change in the surgeons' behavior, without compromising clinical productivity. LEVEL OF EVIDENCE Therapeutic/Care Management; Level III. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2021 AAST QUICK SHOT Source Type: research

Cellular microRNAs correlate with clinical parameters in multiple injury patients
CONCLUSION Systemic microRNAs were associated with poor outcomes in PtPs, and results are consistent with previously described trends in critically ill patients. These early biomarkers of inflammation might provide predictive utility in early complicated recovery diagnosis and prognosis. Because of their potential to regulate immune responses, microRNAs may provide therapeutic targets for immunomodulation. LEVEL OF EVIDENCE Diagnostic Tests/Criteria; Level II. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: 2021 AAST PODIUM PAPER Source Type: research

Another milestone reached: Emergency general surgery verification program
No abstract available (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - September 27, 2022 Category: Surgery Tags: EDITORIAL Source Type: research