Correction: Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 24, 2024 Category: Research Authors: Amir Mohammad Malvandi, Esra Halilaj, Martina Faraldi, Laura Mangiavini, Simone Cristoni, Valerio Leoni and Giovanni Lombardi Tags: Correction Source Type: research
Immunological profile of lactylation-related genes in Crohn ’s disease: a comprehensive analysis based on bulk and single-cell RNA sequencing data
Crohn's disease (CD) is a disease characterized by intestinal immune dysfunction, often accompanied by metabolic abnormalities. Disturbances in lactate metabolism have been found in the intestine of patients w... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 23, 2024 Category: Research Authors: Jingtong Wu, Yinyin Lv, Pei Hao, Ziyi Zhang, Yongtian Zheng, Ermei Chen and Yanyun Fan Tags: Research Source Type: research
An integrated metabo-lipidomics profile of induced sputum for the identification of novel biomarkers in the differential diagnosis of asthma and COPD
Due to their complexity and to the presence of common clinical features, differentiation between asthma and chronic obstructive pulmonary disease (COPD) can be a challenging task, complicated in such cases als... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 23, 2024 Category: Research Authors: Serena Correnti, Mariaimmacolata Preian ò, Fabia Gamboni, Daniel Stephenson, Corrado Pelaia, Girolamo Pelaia, Rocco Savino, Angelo D’Alessandro and Rosa Terracciano Tags: Research Source Type: research
HTRA1-driven detachment of type I collagen from endoplasmic reticulum contributes to myocardial fibrosis in dilated cardiomyopathy
The aberrant secretion and excessive deposition of type I collagen (Col1) are important factors in the pathogenesis of myocardial fibrosis in dilated cardiomyopathy (DCM). However, the precise molecular mechan... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 22, 2024 Category: Research Authors: Hongjie Shi, Ming Yuan, Jie Cai, Lan Lan, Yumou Wang, Wei Wang, Jianliang Zhou, Bin Wang, Wenjun Yu, Zhe Dong, Dawei Deng, Qiaofeng Qian, Yang Li, Xianwu Zhou and Jinping Liu Tags: Research Source Type: research
Statins as a risk factor for diabetic retinopathy: a Mendelian randomization and cross-sectional observational study
Diabetic retinopathy (DR) is the foremost cause of vision loss among the global working-age population, and statins are among the most frequently prescribed drugs for lipid management in patients with DR. The ... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 22, 2024 Category: Research Authors: Chengming Chen, Huan Zhang, Yanyan Lan, Weiming Yan, Sida Liu, Yixuan Chen, Tingke Xie, Jiayi Ning, Xiaolong Yan, Lei Shang and Jing Han Tags: Research Source Type: research
Acylcarnitines promote gallbladder cancer metastasis through lncBCL2L11-THOC5-JNK axis
This study aimed to determine the... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 22, 2024 Category: Research Authors: Yang Yang, Huaifeng Li, Ke Liu, Lu Zou, Shanshan Xiang, Yajun Geng, Xuechuan Li, Shimei Qiu, Jiahua Yang, Xuya Cui, Lin li, Yang Li, Weijian Li, Siyuan Yan, Liguo Liu, Xiangsong Wu & hellip; Tags: Research Source Type: research
Correction: Detecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 21, 2024 Category: Research Authors: William Humphries, Yongtao Wang, Wei Qiao, Chantal Reina-Ortiz, Mohamed K. Abou-Ghazal, Lamonne M. Crutcher, Jun Wei, Ling-Yuan Kong, Raymond Sawaya, Ganesh Rao, Jeffrey Weinberg, Sujit S. Prabhu, Gregory N. Fuller and Amy B. Heimberger Tags: Correction Source Type: research
Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet
Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 21, 2024 Category: Research Authors: Justyna Godos, Francesca Scazzina, Corrado Patern ò Castello, Francesca Giampieri, José L. Quiles, Mercedes Briones Urbano, Maurizio Battino, Fabio Galvano, Licia Iacoviello, Giovanni de Gaetano, Marialaura Bonaccio and Giuseppe Grosso Tags: Review Source Type: research
AURKB promotes bladder cancer progression by deregulating the p53 DNA damage response pathway via MAD2L2
Bladder cancer (BC) is the most common urinary tract malignancy. Aurora kinase B (AURKB), a component of the chromosomal passenger protein complex, affects chromosomal segregation during cell division. Mitotic... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 21, 2024 Category: Research Authors: Linzhi Li, Pengcheng Jiang, Weimin Hu, Fan Zou, Ming Li, Ting Rao, Yuan Ruan, Weimin Yu, Jinzhuo Ning and Fan Cheng Tags: Research Source Type: research
Potential anti-tumor effects of regulatory T cells in the tumor microenvironment: a review
Regulatory T cells (Tregs) expressing the transcription factor FoxP3 are essential for maintaining immunological balance and are a significant component of the immunosuppressive tumor microenvironment (TME). S... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 20, 2024 Category: Research Authors: Yu Li, Cangang Zhang, Aimin Jiang, Anqi Lin, Zaoqu Liu, Xiangshu Cheng, Wanting Wang, Quan Cheng, Jian Zhang, Ting Wei and Peng Luo Tags: Review Source Type: research
Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques
Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and are useful models for cancer immunotherapy; but mechanistic data are lacking regarding the ... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 19, 2024 Category: Research Authors: Simon Deycmar, Brendan J. Johnson, Karina Ray, George W. Schaaf, Declan Patrick Ryan, Cassandra Cullin, Brandy L. Dozier, Betsy Ferguson, Benjamin N. Bimber, John D. Olson, David L. Caudell, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, Emily C. R Tags: Research Source Type: research
The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications
Lipid metabolism is widely reprogrammed in tumor cells. Lipid droplet is a common organelle existing in most mammal cells, and its complex and dynamic functions in maintaining redox and metabolic balance, regu... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 18, 2024 Category: Research Authors: Boer Deng, Weimin Kong, Xiaochang Shen, Chao Han, Ziyi Zhao, Shuning Chen, Chunxiao Zhou and Victoria Bae-Jump Tags: Review Source Type: research
Modulation of hippocampal protein expression by a brain penetrant biologic TNF- α inhibitor in the 3xTg Alzheimer’s disease mice
Biologic TNF- α inhibitors (bTNFIs) can block cerebral TNF-α in Alzheimer’s disease (AD) if these macromolecules can cross the blood–brain barrier (BBB). Thus, a model bTNFI, the extracellular domain of type II... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 18, 2024 Category: Research Authors: Nataraj Jagadeesan, G. Chuli Roules, Devaraj V. Chandrashekar, Joshua Yang, Sanjana Kolluru and Rachita K. Sumbria Tags: Research Source Type: research
Development and validation of predictive models for myopia onset and progression using extensive 15-year refractive data in children and adolescents
Global myopia prevalence poses a substantial public health burden with vision-threatening complications, necessitating effective prevention and control strategies. Precise prediction of spherical equivalent (S... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 17, 2024 Category: Research Authors: Jing Zhao, Yanze Yu, Yiming Li, Feng Li, Zhe Zhang, Weijun Jian, Zhi Chen, Yang Shen, Xiaoying Wang, Zhengqiang Ye, Chencui Huang and Xingtao Zhou Tags: Research Source Type: research
Redox proteomics of PANC-1 cells reveals the significance of HIF-1 signaling protein oxidation in pancreatic ductal adenocarcinoma pathogenesis
Protein cysteine oxidation is substantially involved in various biological and pathogenic processes, but its implications in pancreatic cancer development remains poorly understood. (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - March 16, 2024 Category: Research Authors: Chaochao Tan, Lichun Chen, Xiaoyu Guan, Wenyi Huang, Yinhong Feng, Ziyi Li, Ling Wu, Xiangping Huang, Qianhui Ouyang, Sixiang Liu, Ying Huang and Jiliang Hu Tags: Research Source Type: research
