(Pro)renin receptor mediates tubular epithelial cell pyroptosis in diabetic kidney disease via DPP4-JNK pathway
(Pro)renin receptor (PRR) is highly expressed in renal tubules, which is involved in physiological and pathological processes. However, the role of PRR, expressed in renal tubular epithelial cells, in diabetic... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - January 5, 2024 Category: Research Authors: Shiying Xie, Shicong Song, Sirui Liu, Qiong Li, Wei Zou, Jianting Ke and Cheng Wang Tags: Research Source Type: research
Risk factors for carotid plaque formation in type 2 diabetes mellitus
Patients with type 2 diabetes mellitus (T2DM) are at higher risk of developing atherosclerosis. Previous studies have analyzed the factors associated with diabetic macrovascular disease, although whether these... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - January 4, 2024 Category: Research Authors: Jin Chen, Wenwen Li, Jingzhu Cao, Yuhan Lu, Chaoqun Wang and Jin Lu Tags: Research Source Type: research
Correction: YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - January 4, 2024 Category: Research Authors: Wen G. Jiang, Lin Ye, Fiona Ruge, Sioned Owen, Tracey Martin, Ping ‑Hui Sun, Andrew J. Sanders, Jane Lane, Lucy Satherley, Hoi P. Weeks, Yong Gao, Cong Wei, Yiling Wu and Malcolm D. Mason Tags: Correction Source Type: research
AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF- κB activation in oral squamous cell carcinoma
Radioresistance and lymph node metastasis are common phenotypes of refractory oral squamous cell carcinoma (OSCC). As a result, understanding the mechanism for radioresistance and metastatic progression is urg... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - January 3, 2024 Category: Research Authors: Hui-Wen Chiu, Hsin-Lun Lee, Hsun-Hua Lee, Hsiao-Wei Lu, Kent Yu-Hsien Lin, Yuan-Feng Lin and Che-Hsuan Lin Tags: Research Source Type: research
Virus-like particle-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice
Neoantigens are patient- and tumor-specific peptides that arise from somatic mutations. They stand as promising targets for personalized therapeutic cancer vaccines. The identification process for neoantigens ... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - January 3, 2024 Category: Research Authors: Ana Barajas, Pep Amengual-Rigo, Anna Pons-Gr ífols, Raquel Ortiz, Oriol Gracia Carmona, Victor Urrea, Nuria de la Iglesia, Juan Blanco-Heredia, Carla Anjos-Souza, Ismael Varela, Benjamin Trinité, Ferran Tarrés-Freixas, Carla Rovirosa, Rosalba Lepore, M Tags: Research Source Type: research
