Journal of Traditional Chinese Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Mechanisms of Dangua Fang in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics
CONCLUSION: DGR extensively corrects the modification of phosphorylation sites to improve corresponding glycolipid metabolism-related protein expression in rats with glycolipid metabolism disorders, thereby regulating glycolipid metabolism through a multi-target and multi-method process.PMID:38504539 | PMC:PMC10927395 | DOI:10.19852/j.cnki.jtcm.20230908.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Heng Xianpei Wang Zhita L I Liang Yang Liuqing Huang Suping Jin Lang H E Weidong Source Type: research

Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy
CONCLUSIONS: Acupuncture can inhibit NCOA4-mediated ferritinophagy and protect neurons against CIRI in a rat model.PMID:38504540 | PMC:PMC10927404 | DOI:10.19852/j.cnki.jtcm.20240203.006 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zhang Xinchang Huang Zheng Huang Peiyan Yang Mengning Zhang Zhihui N I Guangxia Source Type: research

Moxibustion of Zusanli (ST36) and Shenshu (BL23) alleviates the inflammation of rheumatoid arthritis in rats through regulating macrophage migration inhibitory factor/glucocorticoids signaling
CONCLUSION: Reducing MIF to increase CORT and decrease TNF-α by moxibustion treatment in RA. MIF may be a factor for moxibustion to regulate the expression of CORT, but the expression of TNF-α is due to the incomplete regulation of the MIF. This study added to the body of evidence pointing to moxibustion's anti-inflammatory mechanism in the treatment of RA.PMID:38504541 | PMC:PMC10927400 | DOI:10.19852/j.cnki.jtcm.20220602.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zhang Linlin Zhong Yumei L U Wenting Shang Yanan Guo Yanding Luo Xiaochao Chen Yang Luo Kun H U Danhui Y U Huiling Zhou Haiyan Source Type: research

Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Sini decoction against renal fibrosis
J Tradit Chin Med. 2024 Apr;44(2):362-372. doi: 10.19852/j.cnki.jtcm.20230630.003.ABSTRACTOBJECTIVE: To investigate the mechanism by which Sini decoction (, SND) improves renal fibrosis (Rf) in rats based on transforming growth factor β1/Smad (TGF-β1/Smad) signaling pathway.METHODS: Network pharmacology was applied to obtain potentially involved signaling pathways in SND's improving effects on Rf. The targets of SND drug components and the targets of Rf were obtained by searching databases, such as the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCSMP) and GeenCard. The intersection ...
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Wang Yan Deng Fanying Liu Shiqi Wang Yingli Source Type: research

Effectiveness and safety of Jiawei Xiaoyao pill in the treatment of premenstrual syndrome (liver depression, spleen deficiency, and blood-heat syndrome): a multi-center, randomized, placebo-controlled trial
CONCLUSIONS: JXP was superior to the placebo in relieving the symptoms associated with PMS, which signified that JXP may be effective, safe, and well-tolerated as an alternative therapy.PMID:38504543 | PMC:PMC10927397 | DOI:10.19852/j.cnki.jtcm.20231110.003 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: L I Xiyu Yang Yanhong Sun Jian Nie Quanfang Liu Lifen L I Guifen Y U Junping Zhang Zhuangjin X U Yi Zou Ting Shi Yun Source Type: research

Effectiveness and safety of Qidong Huoxue decoction in treatment of acute lung injury and acute respiratory distress syndrome: a randomized, controlled trial
CONCLUSIONS: Our study results show that QDHX in combination with conventional drug therapy can significantly reduce some clinical symptoms in patients with ALI/ARDS.PMID:38504544 | PMC:PMC10927401 | DOI:10.19852/j.cnki.jtcm.2024.02.003 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Y U Zhengqiu Y U Liuda Chen Ye L I Mingjing Cai Wanru Source Type: research

Effectivenss of electroacupuncture for skeletal muscle pain in Parkinson's disease: a Clinical randomized controlled trial
CONCLUSION: Electroacupuncture therapy can effectively improve skeletal muscle pain in patients with Parkinson's disease, reduce the muscle hardness of patients, improve patients' daily life ability, and improve patients' emotional disorders. The degree of skeletal muscle pain in PD patients is correlated with motor ability and emotional disorders, but there is no significant correlation between the degree of skeletal muscle pain and the muscle tone of PD patients.PMID:38504545 | PMC:PMC10927396 | DOI:10.19852/j.cnki.jtcm.20240203.004 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Wang Shaosong Sun Jingqing Feng Qingyin L I Bin Wang Xin Yuan Fan Cui Yingxue Source Type: research

Formulation of international standards of Chinese medicine technology: clinical practice guide of Chinese medicine for cough
CONCLUSION: Based on clinical evidence, ancient literature evaluation, and expert consensus, a clinical practice guideline for Traditional Chinese Medicine (TCM) in the treatment of cough was developed, providing the first current clinical practice guideline for domestic and foreign TCM and Western medicine practitioners, especially respiratory professionals at home and abroad.PMID:38504546 | PMC:PMC10927410 | DOI:10.19852/j.cnki.jtcm.20231016.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Fang Hanyu Hong Zheng L I Deming Zhang Hongchun Shi Yihang L I Xiaojuan Sun Zengtao Chen Wei Zhang Chuchu Z U Yaqi Source Type: research

Pharmacological potential of (L.) P. Royen (Sapodilla): a narrative review
J Tradit Chin Med. 2024 Apr;44(2):403-407. doi: 10.19852/j.cnki.jtcm.2024.02.001.ABSTRACTHerbal medicine is safe and effective in treating various diseases. Traditional herbal medicine plays a tremendous role in treatment of various diseases and accompanying complications, hence herbal medicine requires remarkable attention in further research for the development of numerous active formulations for treatment of health troubles. The plant needs special consideration for development and research of unidentified compound and characterization of novel active molecules that overcome multiple pathological abnormalities. The genu...
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Priyanka Sharma Aakash Deep Harish Kumar Nitin Bansal Sanjiv Kumar None Arun Davinder Kumar Source Type: research

Complementary and alternative medicine on cognitive defects and neuroinflammation after sepsis
J Tradit Chin Med. 2024 Apr;44(2):408-416. doi: 10.19852/j.cnki.jtcm.20240203.002.ABSTRACTSepsis-associated encephalopathy (SAE) is a common manifestation of sepsis, ranging from mild confusion and delirium to severe cognitive impairment and deep coma. SAE is associated with higher mortality and long-term outcomes, particularly substantial declines in cognitive function. The mechanisms of SAE probably include neuroinflammation that is mediated by systemic inflammation and ischemic lesions in the brain, a disrupted blood-brain barrier, oxidative stress, neurotransmitter dysfunction, and severe microglial activation. Increas...
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: L I Zhenxuan Wang Xuerui Luis Ulloa Ayman Youssef Bai Yunjing X U Xiaolong Liu Qingquan Source Type: research

Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials
CONCLUSION: The current Meta-analysis revealed that HQ-based TCM yields higher efficacy and safety than Western Medicine alone for the treatment of DPN, although further well-designed RCTs are required to validate these findings.PMID:38504529 | PMC:PMC10927399 | DOI:10.19852/j.cnki.jtcm.2024.02.004 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Ping Jing Hao Hongzheng W U Zhenqi Zou Meijuan L I Zuojing Cheng Gang Source Type: research

Efficacy and safety of extracorporeal shock wave therapy combined with sodium hyaluronate in treatment of knee osteoarthritis: a systematic review and Meta-analysis
CONCLUSIONS: Medium to low quality evidence showed that ESWT combined with HA offers an inexpensive, well-tolerated, safe, and effective method to improve pain and functionality in patients with KOA. However, tightly controlled, randomized, large multicenter trials are warranted to validate the current findings.PMID:38504530 | PMC:PMC10927402 | DOI:10.19852/j.cnki.jtcm.20231226.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zhou Mingwang Dong Zhuanli Wei Changhao Feng Lufang Wang Xiaoping Liu Haiping J I Xing Yang Kehu L I Shenghua Source Type: research

Polyphyllin I enhances tumor necrosis factor-related apoptosis-inducing ligand-induced inhibition of human osteosarcoma cell growth downregulating the Wnt/ β-catenin pathway
CONCLUSION: The combination of PPI and TRAIL is potentially a novel treatment strategy of osteosarcoma.PMID:38504531 | PMC:PMC10927409 | DOI:10.19852/j.cnki.jtcm.2024.02.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Chang Junli Zhao Fulai Sun Xingyuan M A Xiaoping Zhao Peng Zhou Chujie Shi Binhao G U Wenchao Wang Yongjun Yang Yanping Source Type: research

Anti-inflammatory mechanism of the non-volatile ingredients originated from Guanghuoxiang () based on high performance liquid chromatography-heated electron spray ionization-high resolution mass spectroscope and cell metabolomics
CONCLUSION: The non-volatile ingredients of patchouli had good anti-inflammatory effect and exerted its curative effect by regulating endogenous metabolic pathway to reduce inflammatory response.PMID:38504532 | PMC:PMC10927411 | DOI:10.19852/j.cnki.jtcm.20240203.003 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Jing Wenguang Lin Xiaoyu L I Chu Zhao Xiaoliang Cheng Xianlong Wang Penglong Wei Feng M A Shuangcheng Source Type: research

Emodin suppresses alkali burn-induced corneal inflammation and neovascularization by the vascular endothelial growth factor receptor 2 signaling pathway
CONCLUSION: This study provides a new avenue for evaluating the molecular mechanisms underlying corneal inflammation and neovascularization. Emodin might be a promising new therapeutic option for corneal alkali burns.PMID:38504533 | PMC:PMC10927407 | DOI:10.19852/j.cnki.jtcm.20240203.005 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zheng Xueying Guo Liang Lai Siyi L I Fengyue Liang Mingli Liu Wanting Meng Chun Liu Guanghui Source Type: research